1kf6 A 2.7 BS01 OAA A 1 F116 H232 T244 H355 R390 F117 H233 T245 H356 R391 A47 F116 T203 Q230 H232 L242 E245 R248 R287 H355 Y356 R390 A48 F117 T204 Q231 H233 L243 E246 R249 R288 H356 Y357 R391 1.3.5.1 0000104,0000166,0005515,0005829,0005886,0006113,0006974,0008177,0009055,0009061,0016020,0016491,0016627,0019645,0022900,0044780,0045283,0050660,0071949 P00363 11850430 702 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPA 1kf6 A 2.7 BS02 FAD A 1 G11 A15 S36 K37 S43 H44 T45 A48 G50 G51 V157 A191 T192 T203 D211 H355 Y356 E379 R390 S393 S395 L396 L399 G12 A16 S37 K38 S44 H45 T46 A49 G51 G52 V158 A192 T193 T204 D212 H356 Y357 E380 R391 S394 S396 L397 L400 A47 F116 T203 Q230 H232 L242 E245 R248 R287 H355 Y356 R390 A48 F117 T204 Q231 H233 L243 E246 R249 R288 H356 Y357 R391 1.3.5.1 0000104,0000166,0005515,0005829,0005886,0006113,0006974,0008177,0009055,0009061,0016020,0016491,0016627,0019645,0022900,0044780,0045283,0050660,0071949 P00363 11850430 721 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPA 1kf6 B 2.7 BS01 FES B 1 C57 R58 C62 G63 C65 C77 C57 R58 C62 G63 C65 C77 1.3.5.1 0005515,0005829,0005886,0006099,0006113,0008177,0009055,0009061,0016020,0016491,0019645,0044780,0045283,0046872,0051536,0051537,0051538,0051539 P0AC47 11850430 244 AEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACPQFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIATLKPR 1kf6 B 2.7 BS02 F3S B 1 C158 C204 F206 V207 G208 C210 I224 C158 C204 F206 V207 G208 C210 I224 1.3.5.1 0005515,0005829,0005886,0006099,0006113,0008177,0009055,0009061,0016020,0016491,0019645,0044780,0045283,0046872,0051536,0051537,0051538,0051539 P0AC47 11850430 245 AEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACPQFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIATLKPR 1kf6 B 2.7 BS03 SF4 B 1 C148 I149 N150 C151 G152 C154 C214 C148 I149 N150 C151 G152 C154 C214 1.3.5.1 0005515,0005829,0005886,0006099,0006113,0008177,0009055,0009061,0016020,0016491,0019645,0044780,0045283,0046872,0051536,0051537,0051538,0051539 P0AC47 11850430 246 AEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACPQFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIATLKPR 1kf6 B 2.7 BS04 HQO C 1 T205 F206 Q225 K228 T205 F206 Q225 K228 1.3.5.1 0005515,0005829,0005886,0006099,0006113,0008177,0009055,0009061,0016020,0016491,0019645,0044780,0045283,0046872,0051536,0051537,0051538,0051539 -logKd/Ki=6.70, Ki=0.2uM P0AC47 11850430 700 AEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACPQFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIATLKPR 1kf6 C 2.7 BS01 HQO C 1 R28 E29 R28 E29 ? 0000104,0005886,0006113,0009061,0016020,0019645,0044780,0045283 -logKd/Ki=6.70, Ki=0.2uM P0A8Q0 11850430 700 TTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW 1kf6 D 2.7 BS01 HQO C 1 W14 F17 W15 F18 ? 0000104,0005886,0006106,0006113,0009061,0016020,0019645,0044780,0045283 -logKd/Ki=6.70, Ki=0.2uM P0A8Q3 11850430 700 MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGLFPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTLIGVVTI 1kf6 M 2.7 BS01 OAA M 1 F116 H232 L242 T244 H355 R390 F117 H233 L243 T245 H356 R391 F116 H232 R287 H355 Y356 R390 F117 H233 R288 H356 Y357 R391 1.3.5.1 0000104,0000166,0005515,0005829,0005886,0006113,0006974,0008177,0009055,0009061,0016020,0016491,0016627,0019645,0022900,0044780,0045283,0050660,0071949 P00363 11850430 802 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPA 1kf6 M 2.7 BS02 FAD M 1 G11 A12 G13 G14 A15 S36 K37 S43 H44 T45 A48 G50 G51 F156 V157 A191 T192 G193 T203 L242 H355 Y356 E379 R390 S393 S395 L396 L399 G12 A13 G14 G15 A16 S37 K38 S44 H45 T46 A49 G51 G52 F157 V158 A192 T193 G194 T204 L243 H356 Y357 E380 R391 S394 S396 L397 L400 F116 H232 R287 H355 Y356 R390 F117 H233 R288 H356 Y357 R391 1.3.5.1 0000104,0000166,0005515,0005829,0005886,0006113,0006974,0008177,0009055,0009061,0016020,0016491,0016627,0019645,0022900,0044780,0045283,0050660,0071949 P00363 11850430 821 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPA 1kf6 N 2.7 BS01 FES N 1 C57 R58 C62 G63 C65 C77 C57 R58 C62 G63 C65 C77 1.3.5.1 0005515,0005829,0005886,0006099,0006113,0008177,0009055,0009061,0016020,0016491,0019645,0044780,0045283,0046872,0051536,0051537,0051538,0051539 P0AC47 11850430 244 AEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACPQFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIATLKPR 1kf6 N 2.7 BS02 F3S N 1 C158 C204 F206 V207 G208 C210 I224 C158 C204 F206 V207 G208 C210 I224 1.3.5.1 0005515,0005829,0005886,0006099,0006113,0008177,0009055,0009061,0016020,0016491,0019645,0044780,0045283,0046872,0051536,0051537,0051538,0051539 P0AC47 11850430 245 AEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACPQFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIATLKPR 1kf6 N 2.7 BS03 SF4 N 1 C148 I149 N150 C151 G152 C154 C214 V218 C148 I149 N150 C151 G152 C154 C214 V218 1.3.5.1 0005515,0005829,0005886,0006099,0006113,0008177,0009055,0009061,0016020,0016491,0019645,0044780,0045283,0046872,0051536,0051537,0051538,0051539 P0AC47 11850430 246 AEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACPQFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIATLKPR 1kf6 N 2.7 BS04 HQO N 1 T205 F206 Q225 T205 F206 Q225 1.3.5.1 0005515,0005829,0005886,0006099,0006113,0008177,0009055,0009061,0016020,0016491,0019645,0044780,0045283,0046872,0051536,0051537,0051538,0051539 P0AC47 11850430 800 AEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACPQFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIATLKPR 1kf6 O 2.7 BS01 HQO N 1 R28 E29 R28 E29 ? 0000104,0005886,0006113,0009061,0016020,0019645,0044780,0045283 P0A8Q0 11850430 800 TTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW 1kf6 P 2.7 BS01 HQO N 1 W14 F17 W15 F18 ? 0000104,0005886,0006106,0006113,0009061,0016020,0019645,0044780,0045283 P0A8Q3 11850430 800 MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGLFPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTLIGVVTI