1ju9 A 2.0 BS01 ZN A 1 C46 H67 C174 C46 H67 C174 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 1.1.1.1 0004022,0004745,0005737,0005829,0008270,0016491,0042572,0042573,0046872 P00327 11601993 375 STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVISGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF 1ju9 A 2.0 BS02 ZN A 2 C97 C100 C103 C111 C97 C100 C103 C111 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 1.1.1.1 0004022,0004745,0005737,0005829,0008270,0016491,0042572,0042573,0046872 P00327 11601993 376 STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVISGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF 1ju9 A 2.0 BS03 NAD A 1 G201 V203 D223 I224 K228 I269 G201 V203 D223 I224 K228 I269 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 1.1.1.1 0004022,0004745,0005737,0005829,0008270,0016491,0042572,0042573,0046872 Ki=1640uM P00327 11601993 377 STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVISGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF 1ju9 B 2.0 BS01 ZN B 1 C46 H67 C174 C46 H67 C174 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 1.1.1.1 0004022,0004745,0005737,0005829,0008270,0016491,0042572,0042573,0046872 P00327 11601993 375 STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVISGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF 1ju9 B 2.0 BS02 ZN B 2 C97 C100 C103 C111 C97 C100 C103 C111 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 1.1.1.1 0004022,0004745,0005737,0005829,0008270,0016491,0042572,0042573,0046872 P00327 11601993 376 STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVISGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF 1ju9 B 2.0 BS03 NAD B 1 G201 V203 D223 I224 I269 T274 G201 V203 D223 I224 I269 T274 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 C46 R47 S48 H51 H67 E68 C97 C100 C103 C111 D115 C174 T178 R369 1.1.1.1 0004022,0004745,0005737,0005829,0008270,0016491,0042572,0042573,0046872 Ki=1640uM P00327 11601993 377 STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVISGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF