1jk7 A 1.9 BS01 MN A 1 D92 N124 H173 H248 D87 N119 H168 H243 D64 H66 D92 D95 R96 N124 H125 H173 R221 H248 D59 H61 D87 D90 R91 N119 H120 H168 R216 H243 3.1.3.16 0000070,0000165,0000775,0000776,0000781,0001824,0003723,0004721,0004722,0005515,0005521,0005634,0005654,0005694,0005730,0005737,0005739,0005741,0005815,0005829,0005856,0005925,0005977,0006470,0007283,0008157,0016607,0016787,0016791,0017018,0019901,0019903,0019904,0030182,0030496,0032154,0032922,0032991,0042752,0043153,0043197,0044877,0046822,0046872,0048511,0051301,0060252,0072357,0098793,0098794,0098978 P36873 11535607 400 KLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA 1jk7 A 1.9 BS02 MN A 2 D64 H66 D92 D59 H61 D87 D64 H66 D92 D95 R96 N124 H125 H173 R221 H248 D59 H61 D87 D90 R91 N119 H120 H168 R216 H243 3.1.3.16 0000070,0000165,0000775,0000776,0000781,0001824,0003723,0004721,0004722,0005515,0005521,0005634,0005654,0005694,0005730,0005737,0005739,0005741,0005815,0005829,0005856,0005925,0005977,0006470,0007283,0008157,0016607,0016787,0016791,0017018,0019901,0019903,0019904,0030182,0030496,0032154,0032922,0032991,0042752,0043153,0043197,0044877,0046822,0046872,0048511,0051301,0060252,0072357,0098793,0098794,0098978 P36873 11535607 401 KLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA 1jk7 A 1.9 BS03 OKA A 1 R96 H125 I130 Y134 D220 R221 Y272 C273 F276 R91 H120 I125 Y129 D215 R216 Y267 C268 F271 D64 H66 D92 D95 R96 N124 H125 H173 R221 H248 D59 H61 D87 D90 R91 N119 H120 H168 R216 H243 3.1.3.16 0000070,0000165,0000775,0000776,0000781,0001824,0003723,0004721,0004722,0005515,0005521,0005634,0005654,0005694,0005730,0005737,0005739,0005741,0005815,0005829,0005856,0005925,0005977,0006470,0007283,0008157,0016607,0016787,0016791,0017018,0019901,0019903,0019904,0030182,0030496,0032154,0032922,0032991,0042752,0043153,0043197,0044877,0046822,0046872,0048511,0051301,0060252,0072357,0098793,0098794,0098978 -logKd/Ki=8.52, IC50=3nM IC50=>5000nM P36873 11535607 501 KLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA