1il2 A 2.6 BS01 rna C 0 R26 R28 D29 L30 G31 S32 L33 F35 Q46 F48 R64 R76 N82 N84 E93 P109 D111 N113 H114 V115 N116 T117 E118 E119 E171 G172 A173 R217 E219 D220 R222 A223 R225 I343 F433 M447 E482 R549 T557 T558 R26 R28 D29 L30 G31 S32 L33 F35 Q46 F48 R64 R76 N82 N84 E93 P109 D111 N113 H114 V115 N116 T117 E118 E119 E171 G172 A173 R217 E219 D220 R222 A223 R225 I343 F433 M447 E482 R549 T557 T558 E482 G485 R537 E482 G485 R537 6.1.1.12 0000166,0003676,0004812,0004815,0005524,0005737,0005829,0006412,0006418,0006422,0016874 Kd=3uM P21889 11566892 901 ~ 976 MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEDILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVK 1il2 A 2.6 BS02 AMO A 1 E171 S193 Q195 K198 R217 Q226 F229 Q231 H448 E482 V483 G484 G485 R489 L531 A532 G534 R537 E171 S193 Q195 K198 R217 Q226 F229 Q231 H448 E482 V483 G484 G485 R489 L531 A532 G534 R537 E482 G485 R537 E482 G485 R537 6.1.1.12 0000166,0003676,0004812,0004815,0005524,0005737,0005829,0006412,0006418,0006422,0016874 P21889 11566892 831 MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEDILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVK 1il2 B 2.6 BS01 rna D 0 R1026 R1028 D1029 L1030 G1031 S1032 L1033 F1035 Q1046 F1048 R1064 R1078 N1082 N1084 E1093 P1109 D1111 N1113 H1114 V1115 N1116 T1117 R26 R28 D29 L30 G31 S32 L33 F35 Q46 F48 R64 R78 N82 N84 E93 P109 D111 N113 H114 V115 N116 T117 E1482 G1485 R1537 E482 G485 R537 6.1.1.12 0000166,0003676,0004812,0004815,0005524,0005737,0005829,0006412,0006418,0006422,0016874 Kd=3uM P21889 11566892 1902 ~ 1972 MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEDILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVK 1il2 B 2.6 BS02 AMO B 1 E1171 S1193 K1198 R1217 R1225 Q1226 F1229 Q1231 H1448 H1449 E1482 V1483 G1484 G1485 G1486 R1489 L1531 A1532 G1534 R1537 E171 S193 K198 R217 R225 Q226 F229 Q231 H448 H449 E482 V483 G484 G485 G486 R489 L531 A532 G534 R537 E1482 G1485 R1537 E482 G485 R537 6.1.1.12 0000166,0003676,0004812,0004815,0005524,0005737,0005829,0006412,0006418,0006422,0016874 P21889 11566892 1831 MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEDILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVK