1i8j A 1.9 BS01 ZN A 1 C119 C121 C129 C119 C121 C129 K194 K246 K194 K246 4.2.1.24 0000287,0004655,0005829,0006782,0006783,0008270,0016829,0033014,0046872 P0ACB2 11444968 400 TDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR 1i8j A 1.9 BS02 DSB A 1 K194 Y200 F203 R204 R215 Q219 K246 Y269 V271 S272 Y311 K194 Y200 F203 R204 R215 Q219 K246 Y269 V271 S272 Y311 K194 K246 K194 K246 4.2.1.24 0000287,0004655,0005829,0006782,0006783,0008270,0016829,0033014,0046872 -logKd/Ki=4.41, IC50=39uM P0ACB2 11444968 350 TDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR 1i8j B 1.9 BS01 ZN B 1 C119 C121 C129 C119 C121 C129 K194 K246 K194 K246 4.2.1.24 0000287,0004655,0005829,0006782,0006783,0008270,0016829,0033014,0046872 P0ACB2 11444968 400 TDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR 1i8j B 1.9 BS02 DSB B 1 S164 Y191 K194 Y200 F203 R204 R215 Q219 K246 Y269 V271 S272 Y311 S164 Y191 K194 Y200 F203 R204 R215 Q219 K246 Y269 V271 S272 Y311 K194 K246 K194 K246 4.2.1.24 0000287,0004655,0005829,0006782,0006783,0008270,0016829,0033014,0046872 P0ACB2 11444968 350 TDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR