1hvy	A	1.9	BS01	D16	A	1	F80 I108 W109 D218 L221 G222 F225 Y258 M311	F55 I83 W84 D193 L196 G197 F200 Y233 M286	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825			-logKd/Ki=6.54, IC50=0.29uM	IC50=29000nM	P04818	11329255	414 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
1hvy	A	1.9	BS02	UMP	A	1	R50 C195 H196 Q214 R215 S216 D218 N226 H256 Y258	R25 C170 H171 Q189 R190 S191 D193 N201 H231 Y233	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825					P04818	11329255	314 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
1hvy	A	1.9	BS03	UMP	B	1	R175 R176	R150 R151	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825					P04818	11329255	315 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
1hvy	B	1.9	BS01	UMP	A	1	R175 R176	R150 R151	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825					P04818	11329255	314 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
1hvy	B	1.9	BS02	D16	B	1	I108 W109 N112 D218 L221 G222 F225 Y258 M311	I83 W84 N87 D193 L196 G197 F200 Y233 M286	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825			-logKd/Ki=6.54, IC50=0.29uM	IC50=29000nM	P04818	11329255	415 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
1hvy	B	1.9	BS03	UMP	B	1	R50 C195 Q214 R215 S216 D218 N226 H256 Y258	R25 C170 Q189 R190 S191 D193 N201 H231 Y233	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825					P04818	11329255	315 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
1hvy	C	1.9	BS01	D16	C	1	F80 I108 W109 D218 L221 G222 F225 Y258 M311	F55 I83 W84 D193 L196 G197 F200 Y233 M286	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825				IC50=29000nM	P04818	11329255	416 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
1hvy	C	1.9	BS02	UMP	C	1	R50 C195 H196 Q214 R215 S216 D218 N226 H256 Y258	R25 C170 H171 Q189 R190 S191 D193 N201 H231 Y233	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825					P04818	11329255	316 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
1hvy	C	1.9	BS03	UMP	D	1	R175 R176	R150 R151	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825					P04818	11329255	317 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
1hvy	D	1.9	BS01	UMP	C	1	R175 R176	R150 R151	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825					P04818	11329255	316 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
1hvy	D	1.9	BS02	D16	D	1	F80 I108 W109 N112 D218 G222 F225 Y258 M311	F55 I83 W84 N87 D193 G197 F200 Y233 M286	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825				IC50=29000nM	P04818	11329255	417 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
1hvy	D	1.9	BS03	UMP	D	1	R50 C195 H196 Q214 R215 S216 D218 N226 H256 Y258	R25 C170 H171 Q189 R190 S191 D193 N201 H231 Y233	E87 W109 Y135 C195 R215 D218	E62 W84 Y110 C170 R190 D193	2.1.1.45	0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0005829,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0071897,0097421,1901363,1990825					P04818	11329255	317 	PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV