1fj4 A 2.35 BS01 TLM A 1 C163 F229 V270 A271 P272 H298 T300 H333 F390 G391 F392 G394 C162 F228 V269 A270 P271 H297 T299 H332 F389 G390 F391 G393 C163 H298 E309 K328 H333 F390 F392 C162 H297 E308 K327 H332 F389 F391 2.3.1.41 0004315,0005737,0005829,0006633,0016746,0016747,0044281,1903966 Kd=26uM -logKd/Ki=4.59, Kd=26uM IC50=12000nM P0A953 11050088 500 KRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKASRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEGAVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHSLGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATLVMRKL 1fj4 B 2.35 BS01 TLM B 1 C163 F229 V270 A271 H298 T300 H333 F390 G391 F392 G394 C162 F228 V269 A270 H297 T299 H332 F389 G390 F391 G393 C163 H298 E309 K328 H333 F390 F392 C162 H297 E308 K327 H332 F389 F391 2.3.1.41 0004315,0005737,0005829,0006633,0016746,0016747,0044281,1903966 Kd=26uM -logKd/Ki=4.59, Kd=26uM IC50=12000nM P0A953 11050088 501 KRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKASRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEGAVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHSLGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATLVMRKL 1fj4 C 2.35 BS01 TLM C 1 C163 F229 V270 A271 P272 H298 T300 H333 F390 G391 F392 G394 C162 F228 V269 A270 P271 H297 T299 H332 F389 G390 F391 G393 C163 H298 E309 K328 H333 F390 F392 C162 H297 E308 K327 H332 F389 F391 2.3.1.41 0004315,0005737,0005829,0006633,0016746,0016747,0044281,1903966 Kd=26uM IC50=12000nM P0A953 11050088 502 KRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKASRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEGAVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHSLGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATLVMRKL 1fj4 D 2.35 BS01 TLM D 1 C163 F229 A271 P272 H298 T300 H333 F390 G391 G394 C162 F228 A270 P271 H297 T299 H332 F389 G390 G393 C163 H298 E309 K328 H333 F390 F392 C162 H297 E308 K327 H332 F389 F391 2.3.1.41 0004315,0005737,0005829,0006633,0016746,0016747,0044281,1903966 Kd=26uM IC50=12000nM P0A953 11050088 503 KRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKASRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEGAVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHSLGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATLVMRKL