1dwd H 3.0 BS01 peptide L 0 E23 I24 G25 M26 P28 W29 D116 H119 P120 C122 Y134 K135 R137 N159 K202 P204 N205 R206 W207 E8 I9 G10 M11 P13 W14 D113 H116 P117 C119 Y134 K135 R137 N164 K212 P214 N217 R218 W219 3.4.21.5 0004252,0005509,0006508,0007596 P00734 1939071 1C~ 14L IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 1dwd H 3.0 BS02 peptide I 0 F34 K36 R73 T74 R75 Y76 I82 F245 F19 K21 R68 T69 R70 Y71 I78 F257 3.4.21.5 0004252,0005509,0006508,0007596 P00734 1939071 1 ~ 10 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 1dwd H 3.0 BS03 MID H 1 H57 Y60A W60D N98 L99 I174 D189 A190 W215 G216 H43 Y47 W50 N95 L96 I179 D199 A200 W227 G228 3.4.21.5 0004252,0005509,0006508,0007596 -logKd/Ki=8.18, Ki=6.6nM Ki=6nM, IC50=690nM, EC50=750nM P00734 1939071 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF