1db4 A 2.2 BS01 CA A 1 H27 G29 G31 D48 H27 G29 G31 D48 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 P14555 7664108 198 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC 1db4 A 2.2 BS02 CA A 2 F23 Y24 G25 Y112 N114 F23 Y24 G25 Y112 N114 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 P14555 7664108 199 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC 1db4 A 2.2 BS03 8IN A 1 L2 F5 H6 Y21 C28 G29 V30 G31 H47 D48 Y51 K62 L2 F5 H6 Y21 C28 G29 V30 G31 H47 D48 Y51 K62 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 -logKd/Ki=7.24, IC50=0.057uM IC50=57.0nM P14555 7664108 200 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC