1ctr A 2.45 BS01 CA A 1 D20 D22 D24 T26 E31 D20 D22 D24 T26 E31 V35 V35 ? 0000086,0000922,0002027,0005509,0005513,0005515,0005576,0005634,0005654,0005737,0005813,0005819,0005829,0005856,0005876,0005886,0007186,0008076,0010800,0010801,0010856,0010880,0010881,0016020,0016240,0019855,0019901,0021762,0030017,0031432,0031514,0031954,0031982,0032465,0032516,0032991,0034704,0035307,0035458,0043209,0043539,0044305,0044325,0046427,0046872,0048306,0050848,0051343,0051592,0055117,0060314,0060315,0060316,0071346,0071902,0072542,0097225,0098901,0099523,0140056,0140238,1901020,1901842,1901844,1902494,1905913,1990456 P0DP23 7803388 149 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 1ctr A 2.45 BS02 CA A 2 D56 D58 N60 T62 I63 E67 D56 D58 N60 T62 I63 E67 V35 V35 ? 0000086,0000922,0002027,0005509,0005513,0005515,0005576,0005634,0005654,0005737,0005813,0005819,0005829,0005856,0005876,0005886,0007186,0008076,0010800,0010801,0010856,0010880,0010881,0016020,0016240,0019855,0019901,0021762,0030017,0031432,0031514,0031954,0031982,0032465,0032516,0032991,0034704,0035307,0035458,0043209,0043539,0044305,0044325,0046427,0046872,0048306,0050848,0051343,0051592,0055117,0060314,0060315,0060316,0071346,0071902,0072542,0097225,0098901,0099523,0140056,0140238,1901020,1901842,1901844,1902494,1905913,1990456 P0DP23 7803388 150 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 1ctr A 2.45 BS03 CA A 3 D93 D95 N97 Y99 E104 D87 D89 N91 Y93 E98 V35 V35 ? 0000086,0000922,0002027,0005509,0005513,0005515,0005576,0005634,0005654,0005737,0005813,0005819,0005829,0005856,0005876,0005886,0007186,0008076,0010800,0010801,0010856,0010880,0010881,0016020,0016240,0019855,0019901,0021762,0030017,0031432,0031514,0031954,0031982,0032465,0032516,0032991,0034704,0035307,0035458,0043209,0043539,0044305,0044325,0046427,0046872,0048306,0050848,0051343,0051592,0055117,0060314,0060315,0060316,0071346,0071902,0072542,0097225,0098901,0099523,0140056,0140238,1901020,1901842,1901844,1902494,1905913,1990456 P0DP23 7803388 151 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 1ctr A 2.45 BS04 CA A 4 D129 D131 D133 Q135 E140 D123 D125 D127 Q129 E134 V35 V35 ? 0000086,0000922,0002027,0005509,0005513,0005515,0005576,0005634,0005654,0005737,0005813,0005819,0005829,0005856,0005876,0005886,0007186,0008076,0010800,0010801,0010856,0010880,0010881,0016020,0016240,0019855,0019901,0021762,0030017,0031432,0031514,0031954,0031982,0032465,0032516,0032991,0034704,0035307,0035458,0043209,0043539,0044305,0044325,0046427,0046872,0048306,0050848,0051343,0051592,0055117,0060314,0060315,0060316,0071346,0071902,0072542,0097225,0098901,0099523,0140056,0140238,1901020,1901842,1901844,1902494,1905913,1990456 P0DP23 7803388 152 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 1ctr A 2.45 BS05 TFP A 1 M124 E127 A128 V136 M144 M118 E121 A122 V130 M138 V35 V35 ? 0000086,0000922,0002027,0005509,0005513,0005515,0005576,0005634,0005654,0005737,0005813,0005819,0005829,0005856,0005876,0005886,0007186,0008076,0010800,0010801,0010856,0010880,0010881,0016020,0016240,0019855,0019901,0021762,0030017,0031432,0031514,0031954,0031982,0032465,0032516,0032991,0034704,0035307,0035458,0043209,0043539,0044305,0044325,0046427,0046872,0048306,0050848,0051343,0051592,0055117,0060314,0060315,0060316,0071346,0071902,0072542,0097225,0098901,0099523,0140056,0140238,1901020,1901842,1901844,1902494,1905913,1990456 -logKd/Ki=6.00, Kd=1uM Kd=1000nM P0DP23 7803388 153 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA