1cjb A 2.0 BS01 IRP A 1 Y116 E144 D145 I146 D148 T149 G150 K151 T152 K176 F197 V198 L203 Y115 E143 D144 I145 D147 T148 G149 K150 T151 K175 F196 V197 L202 E144 D145 D148 F197 R210 E143 D144 D147 F196 R209 2.4.2.22,2.4.2.8 0000166,0000287,0000310,0004422,0005737,0005829,0006166,0006178,0016757,0032263,0032264,0032265,0046100,0046872,0052657 Kd=1nM P20035 10433693 300 PIPNNPGAGENAFDPVFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLLKGSRGFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVSEDLSCLKGKHVLIVEDIIDTGKTLVKFCEYLKKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPDHFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKA 1cjb A 2.0 BS02 POP A 1 K77 G78 R112 K114 S115 Y116 R210 K76 G77 R111 K113 S114 Y115 R209 E144 D145 D148 F197 R210 E143 D144 D147 F196 R209 2.4.2.22,2.4.2.8 0000166,0000287,0000310,0004422,0005737,0005829,0006166,0006178,0016757,0032263,0032264,0032265,0046100,0046872,0052657 P20035 10433693 400 PIPNNPGAGENAFDPVFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLLKGSRGFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVSEDLSCLKGKHVLIVEDIIDTGKTLVKFCEYLKKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPDHFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKA 1cjb B 2.0 BS01 IRP B 1 Y116 E144 D145 I146 D148 T149 G150 K151 T152 K176 F197 V198 L203 Y115 E143 D144 I145 D147 T148 G149 K150 T151 K175 F196 V197 L202 E144 D145 D148 F197 R210 E143 D144 D147 F196 R209 2.4.2.22,2.4.2.8 0000166,0000287,0000310,0004422,0005737,0005829,0006166,0006178,0016757,0032263,0032264,0032265,0046100,0046872,0052657 Kd=1nM P20035 10433693 300 PIPNNPGAGENAFDPVFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLLKGSRGFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVSEDLSCLKGKHVLIVEDIIDTGKTLVKFCEYLKKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPDHFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKA 1cjb B 2.0 BS02 POP B 1 K77 G78 R112 K114 Y116 R210 K76 G77 R111 K113 Y115 R209 E144 D145 D148 F197 R210 E143 D144 D147 F196 R209 2.4.2.22,2.4.2.8 0000166,0000287,0000310,0004422,0005737,0005829,0006166,0006178,0016757,0032263,0032264,0032265,0046100,0046872,0052657 P20035 10433693 400 PIPNNPGAGENAFDPVFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLLKGSRGFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVSEDLSCLKGKHVLIVEDIIDTGKTLVKFCEYLKKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPDHFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKA 1cjb C 2.0 BS01 IRP C 1 Y116 E144 D145 I146 D148 T149 G150 K151 T152 K176 F197 V198 L203 Y115 E143 D144 I145 D147 T148 G149 K150 T151 K175 F196 V197 L202 E144 D145 D148 F197 R210 E143 D144 D147 F196 R209 2.4.2.22,2.4.2.8 0000166,0000287,0000310,0004422,0005737,0005829,0006166,0006178,0016757,0032263,0032264,0032265,0046100,0046872,0052657 Kd=1nM P20035 10433693 300 PIPNNPGAGENAFDPVFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLLKGSRGFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVSEDLSCLKGKHVLIVEDIIDTGKTLVKFCEYLKKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPDHFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKATSL 1cjb C 2.0 BS02 POP C 1 K77 G78 R112 K114 Y116 D204 R210 K76 G77 R111 K113 Y115 D203 R209 E144 D145 D148 F197 R210 E143 D144 D147 F196 R209 2.4.2.22,2.4.2.8 0000166,0000287,0000310,0004422,0005737,0005829,0006166,0006178,0016757,0032263,0032264,0032265,0046100,0046872,0052657 P20035 10433693 400 PIPNNPGAGENAFDPVFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLLKGSRGFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVSEDLSCLKGKHVLIVEDIIDTGKTLVKFCEYLKKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPDHFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKATSL 1cjb D 2.0 BS01 IRP D 1 Y116 E144 D145 I146 D148 T149 G150 K151 T152 K176 F197 V198 L203 Y115 E143 D144 I145 D147 T148 G149 K150 T151 K175 F196 V197 L202 E144 D145 D148 F197 R210 E143 D144 D147 F196 R209 2.4.2.22,2.4.2.8 0000166,0000287,0000310,0004422,0005737,0005829,0006166,0006178,0016757,0032263,0032264,0032265,0046100,0046872,0052657 Kd=1nM P20035 10433693 300 PIPNNPGAGENAFDPVFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLLKGSRGFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVSEDLSCLKGKHVLIVEDIIDTGKTLVKFCEYLKKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPDHFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKA 1cjb D 2.0 BS02 POP D 1 K77 G78 R112 K114 Y116 R210 K76 G77 R111 K113 Y115 R209 E144 D145 D148 F197 R210 E143 D144 D147 F196 R209 2.4.2.22,2.4.2.8 0000166,0000287,0000310,0004422,0005737,0005829,0006166,0006178,0016757,0032263,0032264,0032265,0046100,0046872,0052657 P20035 10433693 400 PIPNNPGAGENAFDPVFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLLKGSRGFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVSEDLSCLKGKHVLIVEDIIDTGKTLVKFCEYLKKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPDHFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKA