1al8 A 2.2 BS01 FMN A 1 Y25 P77 T78 A79 S106 Q127 Y129 T155 K230 H254 R257 D285 G286 R289 G308 R309 Y25 P77 T78 A79 S106 Q127 Y129 T155 K215 H239 R242 D270 G271 R274 G293 R294 S106 Y129 T155 D157 K230 H254 S106 Y129 T155 D157 K215 H239 1.1.3.15 0003973,0005777,0009853,0009854,0010181,0016491,0051707 P05414 9144771 360 MEITNVNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPRILIDVTNIDMTTTILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLIKNRFVLPPFLTLKNFEGIDLGLSSYVAGQIDRSLSWKDVAWLQTITSLPILVKGVITAEDARLAVQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEISRSHIAADWD 1al8 A 2.2 BS02 DHP A 1 Y24 W108 Y129 F172 H254 R257 Y24 W108 Y129 F166 H239 R242 S106 Y129 T155 D157 K230 H254 S106 Y129 T155 D157 K215 H239 1.1.3.15 0003973,0005777,0009853,0009854,0010181,0016491,0051707 Ki=4.8uM -logKd/Ki=5.32, Ki=4.8uM P05414 9144771 361 MEITNVNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPRILIDVTNIDMTTTILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLIKNRFVLPPFLTLKNFEGIDLGLSSYVAGQIDRSLSWKDVAWLQTITSLPILVKGVITAEDARLAVQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEISRSHIAADWD