1a4r A 2.5 BS01 GDP A 1 A13 V14 G15 K16 T17 C18 F28 Q116 D118 L119 S158 A159 L160 A13 V14 G15 K16 T17 C18 F28 Q116 D118 L119 S158 A159 L160 3.6.5.2 0000139,0000322,0002040,0003015,0003161,0003253,0003924,0003925,0005515,0005525,0005737,0005789,0005813,0005819,0005829,0005856,0005886,0005911,0005925,0006897,0006911,0007015,0007030,0007088,0007097,0007163,0007229,0007264,0007399,0008104,0009653,0010591,0010592,0016020,0016787,0017119,0019901,0021762,0030036,0030141,0030154,0030175,0030225,0030307,0030335,0030425,0030496,0030742,0031252,0031256,0031274,0031333,0031435,0031996,0032427,0032467,0032488,0032956,0032991,0034191,0034329,0034332,0035050,0035088,0036336,0036464,0038189,0042802,0042995,0043005,0043025,0043197,0043410,0043525,0044788,0045177,0045198,0045335,0045740,0046330,0046847,0048549,0048664,0051130,0051233,0051489,0051491,0051492,0051496,0051647,0051649,0051683,0051835,0051897,0051988,0060047,0060071,0060501,0060661,0060997,0061630,0070062,0071346,0071944,0072384,0072686,0086101,0090135,0090316,0098685,0098794,0098978,0099159,0099175,1900026 Kd=9.4pM P60953 10211824 200 MQTIKCVVVGDVAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVL 1a4r B 2.5 BS01 GNH B 1 A213 G215 K216 T217 C218 F228 Q316 D318 L319 S358 A359 L360 A13 G15 K16 T17 C18 F28 Q116 D118 L119 S158 A159 L160 3.6.5.2 0000139,0000322,0002040,0003015,0003161,0003253,0003924,0003925,0005515,0005525,0005737,0005789,0005813,0005819,0005829,0005856,0005886,0005911,0005925,0006897,0006911,0007015,0007030,0007088,0007097,0007163,0007229,0007264,0007399,0008104,0009653,0010591,0010592,0016020,0016787,0017119,0019901,0021762,0030036,0030141,0030154,0030175,0030225,0030307,0030335,0030425,0030496,0030742,0031252,0031256,0031274,0031333,0031435,0031996,0032427,0032467,0032488,0032956,0032991,0034191,0034329,0034332,0035050,0035088,0036336,0036464,0038189,0042802,0042995,0043005,0043025,0043197,0043410,0043525,0044788,0045177,0045198,0045335,0045740,0046330,0046847,0048549,0048664,0051130,0051233,0051489,0051491,0051492,0051496,0051647,0051649,0051683,0051835,0051897,0051988,0060047,0060071,0060501,0060661,0060997,0061630,0070062,0071346,0071944,0072384,0072686,0086101,0090135,0090316,0098685,0098794,0098978,0099159,0099175,1900026 Kd=0.22uM -logKd/Ki=6.66, Kd=0.22uM P60953 10211824 400 MQTIKCVVVGDVAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVL