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BioLiP
Download all results in tab-seperated text for 460725 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    12801 1iql:A (2.7) BS02 XMJ 3.4.21.6 GO:0004252 ... P00742 N/A
    12802 1iqm:A (2.6) BS02 XMK 3.4.21.6 GO:0004252 ... P00742 N/A
    12803 1iqn:A (2.6) BS02 XMC 3.4.21.6 GO:0004252 ... P00742 N/A
    12804 1iqp:A (2.8) BS01 ADP ? GO:0003677 ... Q8U4J3 11545747
    12805 1iqp:B (2.8) BS01 ADP ? GO:0003677 ... Q8U4J3 11545747
    12806 1iqp:C (2.8) BS01 ADP ? GO:0003677 ... Q8U4J3 11545747
    12807 1iqp:E (2.8) BS01 ADP ? GO:0003677 ... Q8U4J3 11545747
    12808 1iqr:A (2.1) BS01 FAD 4.1.99.3 GO:0000166 ... P61497 11707580
    12809 1iqu:A (2.2) BS01 TDR 4.1.99.3 GO:0000166 ... P61497 11707580
    12810 1iqu:A (2.2) BS02 FAD 4.1.99.3 GO:0000166 ... P61497 11707580
    12811 1iqz:A (0.92) BS01 SF4 ? GO:0005506 ... P10245 11827483
    12812 1ir0:A (1.0) BS01 SF4 ? GO:0005506 ... P10245 11827483
    12813 1ir1:A (1.8) BS02 CAP 4.1.1.39 GO:0000287 ... P00875 11866526
    12814 1ir1:B (1.8) BS02 CAP 4.1.1.39 GO:0000287 ... P00875 11866526
    12815 1ir1:C (1.8) BS02 CAP 4.1.1.39 GO:0000287 ... P00875 11866526
    12816 1ir1:D (1.8) BS02 CAP 4.1.1.39 GO:0000287 ... P00875 11866526
    12817 1ir2:A (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12818 1ir2:A (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12819 1ir2:B (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12820 1ir2:B (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12821 1ir2:C (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12822 1ir2:C (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12823 1ir2:D (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12824 1ir2:D (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12825 1ir2:E (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12826 1ir2:E (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12827 1ir2:F (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12828 1ir2:F (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12829 1ir2:G (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12830 1ir2:G (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12831 1ir2:H (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12832 1ir2:H (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12833 1ir2:S (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12834 1ir2:S (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12835 1ir2:T (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12836 1ir2:T (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12837 1ir2:U (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12838 1ir2:U (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12839 1ir2:V (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12840 1ir2:V (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12841 1ir2:W (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12842 1ir2:W (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12843 1ir2:X (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12844 1ir2:X (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12845 1ir2:Y (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12846 1ir2:Y (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12847 1ir2:Z (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12848 1ir2:Z (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    12849 1ir3:A (1.9) BS03 ANP 2.7.10.1 GO:0004672 ... P06213 9312016
    12850 1irc:A (2.17) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 8204590
    12851 1irc:A (2.17) BS02 IMD 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 8204590
    12852 1ird:A (1.25) BS01 HEM ? GO:0004601 ... P69905 N/A
    12853 1ird:B (1.25) BS01 HEM ? GO:0004601 ... P68871 N/A
    12854 1iri:A (2.4) BS01 E4P 5.3.1.9 GO:0001701 ... P06744 12054796
    12855 1iri:B (2.4) BS01 E4P 5.3.1.9 GO:0001701 ... P06744 12054796
    12856 1iri:C (2.4) BS01 E4P 5.3.1.9 GO:0001701 ... P06744 12054796
    12857 1iri:D (2.4) BS01 E4P 5.3.1.9 GO:0001701 ... P06744 12054796
    12858 1irj:B (2.1) BS03 CPS ? GO:0002523 ... P06702 11851337
    12859 1irj:D (2.1) BS03 CPS ? GO:0002523 ... P06702 11851337
    12860 1irj:E (2.1) BS01 CPS ? GO:0002523 ... P06702 11851337
    12861 1irj:G (2.1) BS03 CPS ? GO:0002523 ... P06702 11851337
    12862 1irv:A (1.9) BS01 HEM ? GO:0005515 ... P00044 8718869
    12863 1irw:A (2.0) BS01 HEM ? GO:0005515 ... P00044 8718869
    12864 1is2:A (2.2) BS01 FAD 1.3.3.6 GO:0000038 ... P07872 11872165
    12865 1is2:A (2.2) BS02 FAD 1.3.3.6 GO:0000038 ... P07872 11872165
    12866 1is2:B (2.2) BS01 FAD 1.3.3.6 GO:0000038 ... P07872 11872165
    12867 1is2:B (2.2) BS02 FAD 1.3.3.6 GO:0000038 ... P07872 11872165
    12868 1is3:A (1.45) BS01 BGC ? GO:0005615 ... Q9YIC2 12206768
    12869 1is3:A (1.45) BS02 GAL ? GO:0005615 ... Q9YIC2 12206768
    12870 1is4:A (1.9) BS01 BGC ? GO:0005615 ... Q9YIC2 12206768
    12871 1is4:A (1.9) BS02 GAL ? GO:0005615 ... Q9YIC2 12206768
    12872 1is7:K (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    12873 1is7:K (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    12874 1is7:L (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    12875 1is7:L (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    12876 1is7:M (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    12877 1is7:M (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    12878 1is7:N (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    12879 1is7:N (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    12880 1is7:O (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    12881 1is7:O (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    12882 1is7:P (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    12883 1is7:P (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    12884 1is7:Q (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    12885 1is7:Q (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    12886 1is7:R (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    12887 1is7:R (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    12888 1is7:S (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    12889 1is7:S (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    12890 1is7:T (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    12891 1is7:T (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    12892 1is8:K (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    12893 1is8:K (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    12894 1is8:L (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    12895 1is8:L (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    12896 1is8:M (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    12897 1is8:M (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    12898 1is8:N (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    12899 1is8:N (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    12900 1is8:O (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    12901 1is8:O (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    12902 1is8:P (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    12903 1is8:P (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    12904 1is8:Q (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    12905 1is8:Q (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    12906 1is8:R (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    12907 1is8:R (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    12908 1is8:S (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    12909 1is8:S (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    12910 1is8:T (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    12911 1is8:T (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    12912 1isc:A (1.8) BS02 AZI 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    12913 1isc:B (1.8) BS02 AZI 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    12914 1isg:A (2.6) BS01 AGS 3.2.2.6 GO:0001931 ... Q10588 11866528
    12915 1isg:B (2.6) BS01 AGS 3.2.2.6 GO:0001931 ... Q10588 11866528
    12916 1ish:A (2.4) BS01 ENP 3.2.2.6 GO:0001931 ... Q10588 11866528
    12917 1ish:B (2.4) BS01 ENP 3.2.2.6 GO:0001931 ... Q10588 11866528
    12918 1isi:A (2.1) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    12919 1isi:A (2.1) BS02 ENQ 3.2.2.6 GO:0001931 ... Q10588 11866528
    12920 1isi:B (2.1) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    12921 1isi:B (2.1) BS02 ENQ 3.2.2.6 GO:0001931 ... Q10588 11866528
    12922 1isj:A (2.3) BS01 NMN 3.2.2.6 GO:0001931 ... Q10588 11866528
    12923 1isj:B (2.3) BS01 NMN 3.2.2.6 GO:0001931 ... Q10588 11866528
    12924 1ism:A (3.0) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    12925 1ism:B (3.0) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    12926 1iso:A (1.9) BS01 NAD 1.1.1.42 GO:0000287 ... P08200 8639526
    12927 1isp:A (1.3) BS01 GOL 3.1.1.3 GO:0004806 ... P37957 12077437
    12928 1isr:A (4.0) BS01 GLU ? GO:0004930 ... P23385 11867751
    12929 1iss:A (3.3) BS01 MCG ? GO:0004930 ... P23385 11867751 BindingDB: Ki=>10000nM
    12930 1iss:B (3.3) BS01 MCG ? GO:0004930 ... P23385 11867751 BindingDB: Ki=>10000nM
    12931 1isu:A (1.5) BS01 SF4 ? GO:0009055 ... P33678 1453470
    12932 1isu:B (1.5) BS01 SF4 ? GO:0009055 ... P33678 1453470
    12933 1isv:A (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12934 1isv:A (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12935 1isv:A (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12936 1isv:B (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12937 1isv:B (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12938 1isv:B (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12939 1isw:A (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12940 1isw:A (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12941 1isw:A (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12942 1isw:A (2.1) BS04 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12943 1isw:A (2.1) BS05 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12944 1isw:B (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12945 1isw:B (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12946 1isw:B (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12947 1isw:B (2.1) BS04 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12948 1isw:B (2.1) BS05 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12949 1isw:B (2.1) BS06 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12950 1isx:A (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12951 1isx:A (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12952 1isx:A (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12953 1isx:A (2.1) BS04 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12954 1isx:A (2.1) BS05 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12955 1isx:A (2.1) BS06 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12956 1isx:B (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12957 1isx:B (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12958 1isx:B (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12959 1isx:B (2.1) BS04 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12960 1isx:B (2.1) BS05 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12961 1isx:B (2.1) BS06 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12962 1isx:B (2.1) BS07 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12963 1isy:A (2.1) BS01 BGC 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12964 1isy:A (2.1) BS02 BGC 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12965 1isy:B (2.1) BS01 BGC 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12966 1isy:B (2.1) BS02 BGC 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12967 1isz:A (2.0) BS01 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12968 1isz:A (2.0) BS02 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12969 1isz:B (2.0) BS01 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12970 1isz:B (2.0) BS02 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12971 1it0:A (2.0) BS01 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12972 1it0:A (2.0) BS02 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12973 1it0:B (2.0) BS01 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12974 1it0:B (2.0) BS02 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    12975 1it1:A (-1.00) BS01 HEC ? GO:0009055 ... P00132 12054869
    12976 1it1:A (-1.00) BS02 HEC ? GO:0009055 ... P00132 12054869
    12977 1it1:A (-1.00) BS03 HEC ? GO:0009055 ... P00132 12054869
    12978 1it1:A (-1.00) BS04 HEC ? GO:0009055 ... P00132 12054869
    12979 1it2:A (1.6) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    12980 1it2:B (1.6) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    12981 1it3:A (2.1) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    12982 1it3:B (2.1) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    12983 1it3:C (2.1) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    12984 1it3:D (2.1) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    12985 1it6:A (2.0) BS03 CYU 3.1.3.16 GO:0000070 ... P36873 12015153 MOAD: Ki=4.1nM
    PDBbind: -logKd/Ki=8.39, Ki=4.1nM
    12986 1it6:B (2.0) BS03 CYU 3.1.3.16 GO:0000070 ... P36873 12015153 MOAD: Ki=4.1nM
    12987 1it7:A (2.3) BS03 GUN 2.4.2.48 GO:0002099 ... O58843 12054814
    12988 1it8:A (2.5) BS03 PQ0 2.4.2.48 GO:0002099 ... O58843 12054814
    12989 1itc:A (2.1) BS01 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    12990 1itc:A (2.1) BS02 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    12991 1itc:A (2.1) BS03 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    12992 1itc:A (2.1) BS04 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    12993 1itc:A (2.1) BS05 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    12994 1itc:A (2.1) BS06 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    12995 1itc:A (2.1) BS07 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    12996 1itc:A (2.1) BS08 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    12997 1itc:A (2.1) BS09 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    12998 1itc:A (2.1) BS10 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    12999 1itc:A (2.1) BS11 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    13000 1itc:A (2.1) BS12 GLC 3.2.1.2 GO:0000272 ... P36924 12741813

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218