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BioLiP
Download all results in tab-seperated text for 460725 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    432601 8k5o:h (2.42) BS05 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432602 8k5o:h (2.42) BS06 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432603 8k5o:h (2.42) BS07 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432604 8k5o:i (2.42) BS02 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432605 8k5o:i (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432606 8k5o:i (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432607 8k5o:i (2.42) BS05 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432608 8k5o:i (2.42) BS06 A1LZQ ? GO:0005886 ... A0A0X8X9B2 38411333
    432609 8k5o:k (2.42) BS02 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432610 8k5o:k (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432611 8k5o:k (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432612 8k5o:k (2.42) BS05 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432613 8k5o:k (2.42) BS06 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432614 8k5o:k (2.42) BS07 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432615 8k5o:l (2.42) BS02 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432616 8k5o:l (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432617 8k5o:l (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432618 8k5o:l (2.42) BS05 A1LZQ ? GO:0005886 ... A0A0X8X9B2 38411333
    432619 8k5o:l (2.42) BS06 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432620 8k5o:n (2.42) BS02 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432621 8k5o:n (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432622 8k5o:n (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432623 8k5o:n (2.42) BS05 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432624 8k5o:n (2.42) BS06 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432625 8k5o:n (2.42) BS07 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432626 8k5o:o (2.42) BS02 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432627 8k5o:o (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432628 8k5o:o (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432629 8k5o:o (2.42) BS05 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432630 8k5o:o (2.42) BS06 A1LZQ ? GO:0005886 ... A0A0X8X9B2 38411333
    432631 8k5o:o (2.42) BS07 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432632 8k5o:q (2.42) BS02 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432633 8k5o:q (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432634 8k5o:q (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432635 8k5o:q (2.42) BS05 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432636 8k5o:q (2.42) BS06 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432637 8k5o:q (2.42) BS07 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432638 8k5o:r (2.42) BS02 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432639 8k5o:r (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432640 8k5o:r (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432641 8k5o:r (2.42) BS05 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432642 8k5o:r (2.42) BS06 A1LZQ ? GO:0005886 ... A0A0X8X9B2 38411333
    432643 8k5o:t (2.42) BS02 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432644 8k5o:t (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432645 8k5o:t (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432646 8k5o:t (2.42) BS05 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432647 8k5o:t (2.42) BS06 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432648 8k5o:t (2.42) BS07 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432649 8k5o:u (2.42) BS02 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432650 8k5o:u (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432651 8k5o:u (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432652 8k5o:u (2.42) BS05 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432653 8k5o:u (2.42) BS06 A1LZQ ? GO:0005886 ... A0A0X8X9B2 38411333
    432654 8k5o:w (2.42) BS02 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432655 8k5o:w (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432656 8k5o:w (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432657 8k5o:w (2.42) BS05 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432658 8k5o:w (2.42) BS06 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432659 8k5o:w (2.42) BS07 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432660 8k5o:x (2.42) BS02 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432661 8k5o:x (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432662 8k5o:x (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432663 8k5o:x (2.42) BS05 A1LZQ ? GO:0005886 ... A0A0X8X9B2 38411333
    432664 8k5o:x (2.42) BS06 A1LZM ? GO:0005886 ... A0A0X8X9B2 38411333
    432665 8k5o:z (2.42) BS02 LYC ? GO:0005886 ... A0A0X8XBE4 38411333
    432666 8k5o:z (2.42) BS03 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432667 8k5o:z (2.42) BS04 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432668 8k5o:z (2.42) BS05 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432669 8k5o:z (2.42) BS06 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432670 8k5o:z (2.42) BS07 A1LZM ? GO:0005886 ... A0A0X8XBE4 38411333
    432671 8k5q:A (2.28) BS01 C2E ? GO:0000166 ... Q8ZRC9 38532247
    432672 8k5r:A (3.751) BS01 VQE 2.7.11.22
    2.7.11.23
    GO:0004672 ... P50750 37967851
    432673 8k5s:A (2.65) BS01 VPT N/A GO:0005515 ... P10378 N/A
    432674 8k5s:B (2.65) BS01 VPT N/A GO:0005515 ... P10378 N/A
    432675 8k5t:A (2.8) BS01 VQ5 N/A GO:0005515 ... P10378 N/A
    432676 8k5t:B (2.8) BS01 VQ5 N/A GO:0005515 ... P10378 N/A
    432677 8k5v:A (1.7) BS06 VOC 3.4.24.35 GO:0004222 ... P14780 37952596
    432678 8k5v:B (1.7) BS06 2HP 3.4.24.35 GO:0004222 ... P14780 37952596
    432679 8k5w:A (2.0) BS06 VOO 3.4.24.35 GO:0004222 ... P14780 37952596
    432680 8k5w:B (2.0) BS06 VOO 3.4.24.35 GO:0004222 ... P14780 37952596
    432681 8k5w:B (2.0) BS07 2HP 3.4.24.35 GO:0004222 ... P14780 37952596
    432682 8k5x:A (1.9) BS06 VOZ 3.4.24.35 GO:0004222 ... P14780 37952596
    432683 8k5x:B (1.9) BS06 VOZ 3.4.24.35 GO:0004222 ... P14780 37952596
    432684 8k5x:B (1.9) BS07 2HP 3.4.24.35 GO:0004222 ... P14780 37952596
    432685 8k5y:A (1.52) BS06 VP6 3.4.24.35 GO:0004222 ... P14780 37952596
    432686 8k5y:A (1.52) BS07 2HP 3.4.24.35 GO:0004222 ... P14780 37952596
    432687 8k5y:B (1.52) BS06 VP6 3.4.24.35 GO:0004222 ... P14780 37952596
    432688 8k62:A (1.991) BS02 IAU N/A GO:0000049 ... Q13686 N/A
    432689 8k65:A (2.0) BS02 HEM 7.1.1.9 GO:0004129 ... Q5SJ79 38064560
    432690 8k65:A (2.0) BS03 HAS 7.1.1.9 GO:0004129 ... Q5SJ79 38064560
    432691 8k65:B (2.0) BS01 CUA 7.1.1.9 GO:0004129 ... Q5SJ80 38064560
    432692 8k66:A (2.53) BS01 Y01 ? GO:0005886 ... Q0D9S3 38570642
    432693 8k66:A (2.53) BS02 Y01 ? GO:0005886 ... Q0D9S3 38570642
    432694 8k66:A (2.53) BS03 T7X ? GO:0005886 ... Q0D9S3 38570642
    432695 8k66:A (2.53) BS04 CLR ? GO:0005886 ... Q0D9S3 38570642
    432696 8k66:B (2.53) BS01 Y01 ? GO:0005886 ... Q0D9S3 38570642
    432697 8k66:B (2.53) BS02 Y01 ? GO:0005886 ... Q0D9S3 38570642
    432698 8k66:B (2.53) BS03 T7X ? GO:0005886 ... Q0D9S3 38570642
    432699 8k66:B (2.53) BS04 CLR ? GO:0005886 ... Q0D9S3 38570642
    432700 8k69:A (2.33) BS01 Y01 ? GO:0005886 ... Q93XI5 38570642
    432701 8k69:A (2.33) BS02 Y01 ? GO:0005886 ... Q93XI5 38570642
    432702 8k69:A (2.33) BS03 T7X ? GO:0005886 ... Q93XI5 38570642
    432703 8k69:A (2.33) BS04 CLR ? GO:0005886 ... Q93XI5 38570642
    432704 8k69:B (2.33) BS01 Y01 ? GO:0005886 ... Q93XI5 38570642
    432705 8k69:B (2.33) BS02 Y01 ? GO:0005886 ... Q93XI5 38570642
    432706 8k69:B (2.33) BS03 T7X ? GO:0005886 ... Q93XI5 38570642
    432707 8k69:B (2.33) BS04 CLR ? GO:0005886 ... Q93XI5 38570642
    432708 8k6d:A (1.65) BS01 J7R 2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-
    N/A P0DTD1 38594245
    432709 8k6h:A (1.5) BS01 0NM 4.2.1.104 GO:0003677 ... P00816 37971797
    432710 8k6h:B (1.5) BS01 0NM 4.2.1.104 GO:0003677 ... P00816 37971797
    432711 8k6h:C (1.5) BS01 0NM 4.2.1.104 GO:0003677 ... P00816 37971797
    432712 8k6h:D (1.5) BS01 0NM 4.2.1.104 GO:0003677 ... P00816 37971797
    432713 8k6h:E (1.5) BS01 0NM 4.2.1.104 GO:0003677 ... P00816 37971797
    432714 8k6h:F (1.5) BS01 0NM 4.2.1.104 GO:0003677 ... P00816 37971797
    432715 8k6h:G (1.5) BS01 0NM 4.2.1.104 GO:0003677 ... P00816 37971797
    432716 8k6h:H (1.5) BS01 0NM 4.2.1.104 GO:0003677 ... P00816 37971797
    432717 8k6h:I (1.5) BS01 0NM 4.2.1.104 GO:0003677 ... P00816 37971797
    432718 8k6h:J (1.5) BS01 0NM 4.2.1.104 GO:0003677 ... P00816 37971797
    432719 8k6j:A (2.77) BS01 FAD N/A GO:0005886 ... M1VMF7 N/A
    432720 8k6j:A (2.77) BS02 F3S N/A GO:0005886 ... M1VMF7 N/A
    432721 8k6j:C (2.77) BS01 HEC ? N/A M1V1V5 N/A
    432722 8k6j:C (2.77) BS02 HEC ? N/A M1V1V5 N/A
    432723 8k6j:C (2.77) BS03 HEC ? N/A M1V1V5 N/A
    432724 8k6j:C (2.77) BS04 U10 ? N/A M1V1V5 N/A
    432725 8k6k:A (2.4) BS01 FAD N/A GO:0005886 ... M1VMF7 N/A
    432726 8k6k:A (2.4) BS02 F3S N/A GO:0005886 ... M1VMF7 N/A
    432727 8k6k:C (2.4) BS01 HEC ? N/A M1V1V5 N/A
    432728 8k6k:C (2.4) BS02 HEC ? N/A M1V1V5 N/A
    432729 8k6k:C (2.4) BS03 HEC ? N/A M1V1V5 N/A
    432730 8k6k:C (2.4) BS04 U10 ? N/A M1V1V5 N/A
    432731 8k6l:A (2.92) BS01 IOQ ? GO:0005886 ... Q9Y6L6 37674011
    432732 8k6s:A (1.6) BS01 CO3 4.2.1.104 GO:0003677 ... P00816 37971797
    432733 8k6s:B (1.6) BS01 CO3 4.2.1.104 GO:0003677 ... P00816 37971797
    432734 8k6s:F (1.6) BS01 CO3 4.2.1.104 GO:0003677 ... P00816 37971797
    432735 8k6s:G (1.6) BS01 CO3 4.2.1.104 GO:0003677 ... P00816 37971797
    432736 8k6s:I (1.6) BS01 CO3 4.2.1.104 GO:0003677 ... P00816 37971797
    432737 8k6x:A (1.8) BS01 CO3 4.2.1.104 GO:0003677 ... P00816 37971797
    432738 8k6x:B (1.8) BS01 CO3 4.2.1.104 GO:0003677 ... P00816 37971797
    432739 8k6x:C (1.8) BS01 VQO 4.2.1.104 GO:0003677 ... P00816 37971797
    432740 8k6x:D (1.8) BS01 VQO 4.2.1.104 GO:0003677 ... P00816 37971797
    432741 8k6x:E (1.8) BS01 VQO 4.2.1.104 GO:0003677 ... P00816 37971797
    432742 8k6x:F (1.8) BS01 CO3 4.2.1.104 GO:0003677 ... P00816 37971797
    432743 8k6x:G (1.8) BS01 VQO 4.2.1.104 GO:0003677 ... P00816 37971797
    432744 8k6x:H (1.8) BS01 CO3 4.2.1.104 GO:0003677 ... P00816 37971797
    432745 8k6x:I (1.8) BS01 CO3 4.2.1.104 GO:0003677 ... P00816 37971797
    432746 8k6x:J (1.8) BS01 VQO 4.2.1.104 GO:0003677 ... P00816 37971797
    432747 8k6y:A (2.0) BS02 HEM 7.1.1.9 GO:0004129 ... Q5SJ79 38064560
    432748 8k6y:A (2.0) BS03 HAS 7.1.1.9 GO:0004129 ... Q5SJ79 38064560
    432749 8k6y:B (2.0) BS01 CUA 7.1.1.9 GO:0004129 ... Q5SJ80 38064560
    432750 8k71:A (2.23) BS02 VIZ 1.14.11.30
    1.14.11.n4
    GO:0003714 ... Q9NWT6 37969593
    432751 8k72:A (2.45) BS02 VJF 1.14.11.30
    1.14.11.n4
    GO:0003714 ... Q9NWT6 37969593
    432752 8k73:A (2.02) BS02 VK6 1.14.11.30
    1.14.11.n4
    GO:0003714 ... Q9NWT6 37969593
    432753 8k77:A (3.11) BS01 VLX ? GO:0005783 ... Q7L0J3 38637505
    432754 8k78:A (2.67) BS01 IYC N/A N/A P08581 38074469
    432755 8k79:A (2.8) BS01 IYC N/A N/A P00523 38074469
    432756 8k79:B (2.8) BS01 IYC N/A N/A P00523 38074469
    432757 8k7a:A (4.2) BS01 ATP 3.4.22.-
    7.4.2.-
    GO:0005524 ... P59653 37935699
    432758 8k7a:A (4.2) BS03 ATP 3.4.22.-
    7.4.2.-
    GO:0005524 ... P59653 37935699
    432759 8k7a:B (4.2) BS01 ATP 3.4.22.-
    7.4.2.-
    GO:0005524 ... P59653 37935699
    432760 8k7a:B (4.2) BS02 ATP 3.4.22.-
    7.4.2.-
    GO:0005524 ... P59653 37935699
    432761 8k7b:A (3.9) BS01 AOV 7.6.2.5 GO:0005524 ... Q9NP58 37735522
    432762 8k7b:A (3.9) BS03 AOV 7.6.2.5 GO:0005524 ... Q9NP58 37735522
    432763 8k7b:B (3.9) BS01 AOV 7.6.2.5 GO:0005524 ... Q9NP58 37735522
    432764 8k7b:B (3.9) BS02 AOV 7.6.2.5 GO:0005524 ... Q9NP58 37735522
    432765 8k7c:A (3.9) BS01 ADP 7.6.2.5 GO:0005524 ... Q9NP58 37735522
    432766 8k7c:A (3.9) BS03 ADP 7.6.2.5 GO:0005524 ... Q9NP58 37735522
    432767 8k7c:B (3.9) BS01 ADP 7.6.2.5 GO:0005524 ... Q9NP58 37735522
    432768 8k7c:B (3.9) BS02 ADP 7.6.2.5 GO:0005524 ... Q9NP58 37735522
    432769 8k7d:A (2.61) BS01 VLN 3.2.1.22 GO:0003824 ... P06280 38559739
    432770 8k7d:B (2.61) BS01 VLN 3.2.1.22 GO:0003824 ... P06280 38559739
    432771 8k7e:A (2.2) BS01 VLN 3.2.1.22 GO:0003824 ... P06280 38559739
    432772 8k7e:B (2.2) BS01 VLN 3.2.1.22 GO:0003824 ... P06280 38559739
    432773 8k7f:A (1.98) BS01 VMF 3.2.1.22 GO:0003824 ... P06280 38559739
    432774 8k7f:B (1.98) BS01 VMF 3.2.1.22 GO:0003824 ... P06280 38559739
    432775 8k7g:A (2.32) BS01 VMF 3.2.1.22 GO:0003824 ... P06280 38559739
    432776 8k7g:B (2.32) BS01 VMF 3.2.1.22 GO:0003824 ... P06280 38559739
    432777 8k7h:A (2.28) BS01 VMO 3.2.1.22 GO:0003824 ... P06280 38559739
    432778 8k7h:B (2.28) BS01 VMO 3.2.1.22 GO:0003824 ... P06280 38559739
    432779 8k7i:A (2.12) BS01 VN0 3.2.1.22 GO:0003824 ... P06280 38559739
    432780 8k7i:B (2.12) BS01 VN0 3.2.1.22 GO:0003824 ... P06280 38559739
    432781 8k7j:A (2.01) BS01 VNB 3.2.1.22 GO:0003824 ... P06280 38559739
    432782 8k7j:B (2.01) BS01 VNB 3.2.1.22 GO:0003824 ... P06280 38559739
    432783 8k7k:A (2.0) BS01 VNQ 3.2.1.22 GO:0003824 ... P06280 38559739
    432784 8k7k:B (2.0) BS01 VNQ 3.2.1.22 GO:0003824 ... P06280 38559739
    432785 8k7l:A (2.0) BS01 VO0 3.2.1.22 GO:0003824 ... P06280 38559739
    432786 8k7l:B (2.0) BS01 VO0 3.2.1.22 GO:0003824 ... P06280 38559739
    432787 8k7p:A (2.19) BS01 4I1 3.1.1.3 N/A A0A0U1MWF9 38757397
    432788 8k7p:B (2.19) BS01 4I1 3.1.1.3 N/A A0A0U1MWF9 38757397
    432789 8k7p:B (2.19) BS02 6NA 3.1.1.3 N/A A0A0U1MWF9 38757397
    432790 8k7q:A (2.02) BS01 4I1 3.1.1.3 N/A A0A0U1MWF9 38757397
    432791 8k7q:B (2.02) BS01 4I1 3.1.1.3 N/A A0A0U1MWF9 38757397
    432792 8k7q:B (2.02) BS02 6NA 3.1.1.3 N/A A0A0U1MWF9 38757397
    432793 8k7v:A (3.17) BS01 VQX N/A GO:0004557 ... A0A1C7IHX3 N/A
    432794 8k7v:B (3.17) BS01 VQX N/A GO:0004557 ... A0A1C7IHX3 N/A
    432795 8k7v:C (3.17) BS01 VQX N/A GO:0004557 ... A0A1C7IHX3 N/A
    432796 8k7v:D (3.17) BS01 VQX N/A GO:0004557 ... A0A1C7IHX3 N/A
    432797 8k82:Lj (3.0) BS03 T1C N/A GO:0000448 ... P49166 38942792
    432798 8k8e:C (2.6) BS01 CLR ? GO:0000139 ... Q96BI3 38349793
    432799 8k8j:R (2.88) BS01 J3O ? GO:0004930 ... P0ABE7
    P21554
    38298116
    432800 8k8l:A (1.77) BS01 MOO ? GO:0015689 ... A0A0H3GU89 37751633

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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