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BioLiP
Download all results in tab-seperated text for 39065 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • The sequence is converted from residues with experimentally determined coordinates in the structure; residues not observed in the 3D structure are excluded.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (resolution)
    Site
    #
    Peptide
    sequence
    EC
    number
    GO
    terms
    UniProt PubMed Binding
    affinity
    21201 6bxg:A
    (1.45)
    BS01 >6bxg:B
    LIA
    ? N/A Q9KRY7 N/A
    21202 6bxp:A
    (1.45)
    BS01 >6bxp:C
    RVKHLF
    ? N/A P01889 29437277
    21203 6bxq:B
    (1.58)
    BS01 >6bxq:A
    RVKEQHLW
    ? N/A P01889 29437277
    21204 6byj:A
    (2.9)
    BS01 >6byj:G
    ATPPVSQASSTTT
    ? GO:0002842 ... P61981 29784830
    21205 6byj:C
    (2.9)
    BS01 >6byj:T
    VSQASST
    ? GO:0002842 ... P61981 29784830
    21206 6byj:D
    (2.9)
    BS01 >6byj:P
    PPVSQAS
    ? GO:0002842 ... P61981 29784830
    21207 6byk:A
    (3.0)
    BS01 >6byk:K
    PVSQA
    ? GO:0004860 ... P31946 29784830
    21208 6byk:B
    (3.0)
    BS01 >6byk:G (identical to 6byk:J)
    PPVSQASST
    ? GO:0004860 ... P31946 29784830
    21209 6byk:C
    (3.0)
    BS01 >6byk:R
    VSQAS
    ? GO:0004860 ... P31946 29784830
    21210 6byk:D
    (3.0)
    BS01 >6byk:J (identical to 6byk:G)
    PPVSQASST
    ? GO:0004860 ... P31946 29784830
    21211 6byl:A
    (3.35)
    BS01 >6byl:G
    TTVPVTTATTTTT
    ? GO:0002842 ... P61981 29784830
    21212 6byl:C
    (3.35)
    BS01 >6byl:T
    VPVTT
    ? GO:0002842 ... P61981 29784830
    21213 6byl:D
    (3.35)
    BS01 >6byl:P
    VPVTTAT
    ? GO:0002842 ... P61981 29784830
    21214 6byz:A
    (2.95625)
    BS01 >6byz:D (identical to 6avz:E, 6byz:E, 4c2c:B, 4c2f:B, 4d2d:B, 3e4a:F, 3e4a:G, 3flo:I, 3flo:J, 3flo:K, 3flo:L, 6hwn:H, 6hwn:I, 6hwn:J, 6hwn:K, 6hwn:L, 6hwn:M, 6hwn:N, 4iel:C, 3jv2:C, 3jv2:D, 4pes:C, 4pes:D, 7pub:UK, 3qo6:G, 6r0q:F, 6r0q:E, 6r18:D, 1rqf:P, 3tcf:I, 3tcf:J, 3tcf:K, 3tcf:L, 3tcf:M, 3tcf:N, 3tcf:O, 3tcf:P, 4tpj:C, 4tpj:E, 3tuv:B, 6xov:C, 7xs0:B, 5y2d:B, 5yl7:B, 4ynn:Q, 4ynn:R, 4ynn:S, 4ynn:T, 4ynn:U, 4ynn:V, 2zl2:R)
    AAA
    3.4.24.56 GO:0001618 ... P14735 31086331
    21215 6byz:B
    (2.95625)
    BS01 >6byz:E (identical to 6avz:E, 6byz:D, 4c2c:B, 4c2f:B, 4d2d:B, 3e4a:F, 3e4a:G, 3flo:I, 3flo:J, 3flo:K, 3flo:L, 6hwn:H, 6hwn:I, 6hwn:J, 6hwn:K, 6hwn:L, 6hwn:M, 6hwn:N, 4iel:C, 3jv2:C, 3jv2:D, 4pes:C, 4pes:D, 7pub:UK, 3qo6:G, 6r0q:F, 6r0q:E, 6r18:D, 1rqf:P, 3tcf:I, 3tcf:J, 3tcf:K, 3tcf:L, 3tcf:M, 3tcf:N, 3tcf:O, 3tcf:P, 4tpj:C, 4tpj:E, 3tuv:B, 6xov:C, 7xs0:B, 5y2d:B, 5yl7:B, 4ynn:Q, 4ynn:R, 4ynn:S, 4ynn:T, 4ynn:U, 4ynn:V, 2zl2:R)
    AAA
    3.4.24.56 GO:0001618 ... P14735 31086331
    21216 6bz3:A
    (2.497)
    BS01 >6bz3:B
    DDLSEQMASLEGLMKQLN
    2.7.10.2 GO:0004713 ... P34152 29479476
    21217 6bz3:A
    (2.497)
    BS02 >6bz3:D
    DDLSEQMASLEGLMKQLNA
    2.7.10.2 GO:0004713 ... P34152 29479476
    21218 6bz3:C
    (2.497)
    BS01 >6bz3:B
    DDLSEQMASLEGLMKQLN
    2.7.10.2 GO:0004713 ... P34152 29479476
    21219 6bz3:C
    (2.497)
    BS02 >6bz3:D
    DDLSEQMASLEGLMKQLNA
    2.7.10.2 GO:0004713 ... P34152 29479476
    21220 6bz9:A
    (1.796)
    BS01 >6bz9:C
    FLTD
    3.4.22.36 GO:0004197 ... P29466 29891674
    21221 6bz9:B
    (1.796)
    BS01 >6bz9:C
    FLTD
    3.4.22.36 GO:0004197 ... P29466 29891674
    21222 6bzd:A
    (2.67)
    BS01 >6bzd:G (identical to 6bzd:K)
    TPPVSQASSTT
    ? GO:0002842 ... P61981 29784830
    21223 6bzd:B
    (2.67)
    BS01 >6bzd:K (identical to 6bzd:G)
    TPPVSQASSTT
    ? GO:0002842 ... P61981 29784830
    21224 6bzu:A
    (2.7)
    BS01 >6bzu:J
    QLINTNGSWH
    N/A N/A N/A 29954862
    21225 6bzu:B
    (2.7)
    BS01 >6bzu:J
    QLINTNGSWH
    N/A N/A N/A 29954862
    21226 6bzu:C
    (2.7)
    BS01 >6bzu:I (identical to 6bzv:I, 6bzw:I, 6bzw:K, 6bzw:L)
    LINTNGSWH
    N/A N/A N/A 29954862
    21227 6bzu:D
    (2.7)
    BS01 >6bzu:I (identical to 6bzv:I, 6bzw:I, 6bzw:K, 6bzw:L)
    LINTNGSWH
    N/A N/A N/A 29954862
    21228 6bzu:E
    (2.7)
    BS01 >6bzu:K (identical to 6bzy:B)
    QLINTNGSWHI
    N/A N/A N/A 29954862
    21229 6bzu:F
    (2.7)
    BS01 >6bzu:K (identical to 6bzy:B)
    QLINTNGSWHI
    N/A N/A N/A 29954862
    21230 6bzu:G
    (2.7)
    BS01 >6bzu:L (identical to 4dgy:A, 4g6a:B, 4g6a:A, 4hs6:Z, 4hs6:Y, 4hs8:A)
    QLINTNGSWHIN
    N/A N/A N/A 29954862
    21231 6bzu:H
    (2.7)
    BS01 >6bzu:L (identical to 4dgy:A, 4g6a:B, 4g6a:A, 4hs6:Z, 4hs6:Y, 4hs8:A)
    QLINTNGSWHIN
    N/A N/A N/A 29954862
    21232 6bzv:A
    (2.654)
    BS01 >6bzv:I (identical to 6bzu:I, 6bzw:I, 6bzw:K, 6bzw:L)
    LINTNGSWH
    N/A N/A N/A 29954862
    21233 6bzv:B
    (2.654)
    BS01 >6bzv:I (identical to 6bzu:I, 6bzw:I, 6bzw:K, 6bzw:L)
    LINTNGSWH
    N/A N/A N/A 29954862
    21234 6bzv:C
    (2.654)
    BS01 >6bzv:J (identical to 6bzv:K, 6bzw:J, 4gaj:P)
    LINTNGSWHI
    N/A N/A N/A 29954862
    21235 6bzv:D
    (2.654)
    BS01 >6bzv:J (identical to 6bzv:K, 6bzw:J, 4gaj:P)
    LINTNGSWHI
    N/A N/A N/A 29954862
    21236 6bzv:E
    (2.654)
    BS01 >6bzv:K (identical to 6bzv:J, 6bzw:J, 4gaj:P)
    LINTNGSWHI
    N/A N/A N/A 29954862
    21237 6bzv:F
    (2.654)
    BS01 >6bzv:K (identical to 6bzv:J, 6bzw:J, 4gaj:P)
    LINTNGSWHI
    N/A N/A N/A 29954862
    21238 6bzv:G
    (2.654)
    BS01 >6bzv:L
    LINTNGSWHIN
    N/A N/A N/A 29954862
    21239 6bzv:H
    (2.654)
    BS01 >6bzv:L
    LINTNGSWHIN
    N/A N/A N/A 29954862
    21240 6bzw:A
    (2.2)
    BS01 >6bzw:J (identical to 6bzv:J, 6bzv:K, 4gaj:P)
    LINTNGSWHI
    N/A N/A N/A 29954862
    21241 6bzw:B
    (2.2)
    BS01 >6bzw:J (identical to 6bzv:J, 6bzv:K, 4gaj:P)
    LINTNGSWHI
    N/A N/A N/A 29954862
    21242 6bzw:B
    (2.2)
    BS02 >6bzw:K (identical to 6bzu:I, 6bzv:I, 6bzw:I, 6bzw:L)
    LINTNGSWH
    N/A N/A N/A 29954862
    21243 6bzw:C
    (2.2)
    BS01 >6bzw:I (identical to 6bzu:I, 6bzv:I, 6bzw:K, 6bzw:L)
    LINTNGSWH
    N/A N/A N/A 29954862
    21244 6bzw:D
    (2.2)
    BS01 >6bzw:I (identical to 6bzu:I, 6bzv:I, 6bzw:K, 6bzw:L)
    LINTNGSWH
    N/A N/A N/A 29954862
    21245 6bzw:D
    (2.2)
    BS02 >6bzw:L (identical to 6bzu:I, 6bzv:I, 6bzw:I, 6bzw:K)
    LINTNGSWH
    N/A N/A N/A 29954862
    21246 6bzw:E
    (2.2)
    BS01 >6bzw:K (identical to 6bzu:I, 6bzv:I, 6bzw:I, 6bzw:L)
    LINTNGSWH
    N/A N/A N/A 29954862
    21247 6bzw:F
    (2.2)
    BS01 >6bzw:K (identical to 6bzu:I, 6bzv:I, 6bzw:I, 6bzw:L)
    LINTNGSWH
    N/A N/A N/A 29954862
    21248 6bzw:G
    (2.2)
    BS01 >6bzw:L (identical to 6bzu:I, 6bzv:I, 6bzw:I, 6bzw:K)
    LINTNGSWH
    N/A N/A N/A 29954862
    21249 6bzw:H
    (2.2)
    BS01 >6bzw:L (identical to 6bzu:I, 6bzv:I, 6bzw:I, 6bzw:K)
    LINTNGSWH
    N/A N/A N/A 29954862
    21250 6bzy:H
    (1.6)
    BS01 >6bzy:B (identical to 6bzu:K)
    QLINTNGSWHI
    N/A N/A N/A 29954862
    21251 6bzy:L
    (1.6)
    BS01 >6bzy:B (identical to 6bzu:K)
    QLINTNGSWHI
    N/A N/A N/A 29954862
    21252 6c0a:A
    (-1.00)
    BS01 >6c0a:B
    GKFYATFLIQEYFRKFKKRKEQG
    ? N/A Q7TPR4 N/A
    21253 6c0f:b
    (3.7)
    BS02 >6c0f:x (identical to 6cb1:x, 4fby:Y, 4fby:k, 6h8k:P, 4ixq:Y, 4ixr:Y, 4tnh:Y, 4tnh:G, 4tni:Y, 4tni:G, 4tnj:Y, 4tnj:G, 4tnk:Y, 4tnk:G, 6uxv:K, 6uxw:K, 4v62:AY, 4v62:BY, 4v82:AY, 6v8o:2, 6v92:2, 5vy9:P, 7w3b:v)
    AAAAAAAAAAAAAAAAAAAAAAAAAAAA
    ? GO:0000027 ... Q08235 29512650
    21254 6c0h:A
    (1.9)
    BS01 >6c0h:C
    QACAFGPFPFVCDG
    ? N/A A0A3F2YLX1 30177849
    21255 6c0h:B
    (1.9)
    BS01 >6c0h:C
    QACAFGPFPFVCDG
    ? N/A A0A3F2YLX1 30177849
    21256 6c0y:A
    (1.66)
    BS01 >6c0y:I (identical to 6c0y:O, 6c0y:J, 6c0y:K, 6c0y:N, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21257 6c0y:A
    (1.66)
    BS02 >6c0y:M
    QACAFGPFPFVCDGN
    ? N/A A0A3F2YLX1 30177849
    21258 6c0y:A
    (1.66)
    BS03 >6c0y:N (identical to 6c0y:O, 6c0y:I, 6c0y:J, 6c0y:K, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21259 6c0y:B
    (1.66)
    BS01 >6c0y:J (identical to 6c0y:O, 6c0y:I, 6c0y:K, 6c0y:N, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21260 6c0y:B
    (1.66)
    BS02 >6c0y:N (identical to 6c0y:O, 6c0y:I, 6c0y:J, 6c0y:K, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21261 6c0y:C
    (1.66)
    BS01 >6c0y:O (identical to 6c0y:I, 6c0y:J, 6c0y:K, 6c0y:N, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21262 6c0y:C
    (1.66)
    BS02 >6c0y:K (identical to 6c0y:O, 6c0y:I, 6c0y:J, 6c0y:N, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21263 6c0y:C
    (1.66)
    BS03 >6c0y:P (identical to 6c0y:O, 6c0y:I, 6c0y:J, 6c0y:K, 6c0y:N)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21264 6c0y:D
    (1.66)
    BS01 >6c0y:L
    CKQACAFGPFPFVCDGNP
    ? N/A A0A3F2YLX1 30177849
    21265 6c0y:D
    (1.66)
    BS02 >6c0y:P (identical to 6c0y:O, 6c0y:I, 6c0y:J, 6c0y:K, 6c0y:N)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21266 6c0y:E
    (1.66)
    BS01 >6c0y:I (identical to 6c0y:O, 6c0y:J, 6c0y:K, 6c0y:N, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21267 6c0y:E
    (1.66)
    BS02 >6c0y:M
    QACAFGPFPFVCDGN
    ? N/A A0A3F2YLX1 30177849
    21268 6c0y:F
    (1.66)
    BS01 >6c0y:I (identical to 6c0y:O, 6c0y:J, 6c0y:K, 6c0y:N, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21269 6c0y:F
    (1.66)
    BS02 >6c0y:J (identical to 6c0y:O, 6c0y:I, 6c0y:K, 6c0y:N, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21270 6c0y:F
    (1.66)
    BS03 >6c0y:N (identical to 6c0y:O, 6c0y:I, 6c0y:J, 6c0y:K, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21271 6c0y:G
    (1.66)
    BS01 >6c0y:O (identical to 6c0y:I, 6c0y:J, 6c0y:K, 6c0y:N, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21272 6c0y:G
    (1.66)
    BS02 >6c0y:K (identical to 6c0y:O, 6c0y:I, 6c0y:J, 6c0y:N, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21273 6c0y:H
    (1.66)
    BS01 >6c0y:K (identical to 6c0y:O, 6c0y:I, 6c0y:J, 6c0y:N, 6c0y:P)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21274 6c0y:H
    (1.66)
    BS02 >6c0y:L
    CKQACAFGPFPFVCDGNP
    ? N/A A0A3F2YLX1 30177849
    21275 6c0y:H
    (1.66)
    BS03 >6c0y:P (identical to 6c0y:O, 6c0y:I, 6c0y:J, 6c0y:K, 6c0y:N)
    CKQACAFGPFPFVCDGNPK
    ? N/A A0A3F2YLX1 30177849
    21276 6c1d:C
    (3.2)
    BS01 >6c1d:F
    ATCPAWL
    3.6.4.- GO:0000287 ... P68135 29358376
    21277 6c1d:D
    (3.2)
    BS01 >6c1d:F
    ATCPAWL
    3.6.4.- GO:0000287 ... P68135 29358376
    21278 6c1q:B
    (2.9)
    BS01 >6c1q:L (identical to 6c1r:L)
    FPPAWR
    ? GO:0004875 ... P0ABE7
    P21730
    29867214
    21279 6c1r:B
    (2.2)
    BS01 >6c1r:L (identical to 6c1q:L)
    FPPAWR
    ? GO:0004875 ... P0ABE7
    P21730
    29867214
    21280 6c23:A
    (3.9)
    BS01 >6c23:E (identical to 6c24:E)
    PATQISDLSKRKPKTEDFLTFLCLRGS
    ? GO:0000122 ... Q15022 29348366
    21281 6c23:K
    (3.9)
    BS01 >6c23:O (identical to 6c24:O)
    AAARKFA
    2.1.1.356 GO:0000082 ... Q15910 29348366
    21282 6c23:L
    (3.9)
    BS01 >6c23:B
    KRPRLQAQRKFAQ
    ? GO:0000122 ... O75530 29348366
    21283 6c23:Q
    (3.9)
    BS01 >6c23:E (identical to 6c24:E)
    PATQISDLSKRKPKTEDFLTFLCLRGS
    ? GO:0000122 ... Q15022 29348366
    21284 6c24:A
    (3.5)
    BS01 >6c24:E (identical to 6c23:E)
    PATQISDLSKRKPKTEDFLTFLCLRGS
    ? GO:0000122 ... Q15022 29348366
    21285 6c24:K
    (3.5)
    BS01 >6c24:O (identical to 6c23:O)
    AAARKFA
    2.1.1.356 GO:0000082 ... Q15910 29348366
    21286 6c24:L
    (3.5)
    BS01 >6c24:B
    AQRKFAQ
    ? GO:0000122 ... O75530 29348366
    21287 6c24:Q
    (3.5)
    BS01 >6c24:E (identical to 6c23:E)
    PATQISDLSKRKPKTEDFLTFLCLRGS
    ? GO:0000122 ... Q15022 29348366
    21288 6c48:A
    (2.32)
    BS01 >6c48:C (identical to 6c48:F)
    SAWKTVACGGTRDQLFMQEKARQLLGRL
    ? GO:0006351 ... Q5TKA1 30224471
    21289 6c48:B
    (2.32)
    BS01 >6c48:F (identical to 6c48:C)
    SAWKTVACGGTRDQLFMQEKARQLLGRL
    ? GO:0006355 ... Q52LA3 30224471
    21290 6c48:B
    (2.32)
    BS02 >6c48:C (identical to 6c48:F)
    SAWKTVACGGTRDQLFMQEKARQLLGRL
    ? GO:0006355 ... Q52LA3 30224471
    21291 6c48:D
    (2.32)
    BS01 >6c48:F (identical to 6c48:C)
    SAWKTVACGGTRDQLFMQEKARQLLGRL
    ? GO:0006351 ... Q5TKA1 30224471
    21292 6c48:E
    (2.32)
    BS01 >6c48:F (identical to 6c48:C)
    SAWKTVACGGTRDQLFMQEKARQLLGRL
    ? GO:0006355 ... Q52LA3 30224471
    21293 6c48:E
    (2.32)
    BS02 >6c48:C (identical to 6c48:F)
    SAWKTVACGGTRDQLFMQEKARQLLGRL
    ? GO:0006355 ... Q52LA3 30224471
    21294 6c4u:A
    (2.6)
    BS01 >6c4u:G (identical to 6c4u:I, 6c4u:H, 6c4u:J)
    LLPTPPLS
    2.7.12.1 N/A P22216 29763736
    21295 6c4u:B
    (2.6)
    BS01 >6c4u:H (identical to 6c4u:G, 6c4u:I, 6c4u:J)
    LLPTPPLS
    2.7.12.1 N/A P22216 29763736
    21296 6c4u:C
    (2.6)
    BS01 >6c4u:I (identical to 6c4u:G, 6c4u:H, 6c4u:J)
    LLPTPPLS
    2.7.12.1 N/A P22216 29763736
    21297 6c4u:D
    (2.6)
    BS01 >6c4u:J (identical to 6c4u:G, 6c4u:I, 6c4u:H)
    LLPTPPLS
    2.7.12.1 N/A P22216 29763736
    21298 6c4u:E
    (2.6)
    BS01 >6c4u:K
    KLLPTPPL
    2.7.12.1 N/A P22216 29763736
    21299 6c4u:F
    (2.6)
    BS01 >6c4u:L
    LPTPPL
    2.7.12.1 N/A P22216 29763736
    21300 6c5x:A
    (3.105)
    BS01 >6c5x:G
    EYSTV
    ? GO:0035556 ... C0LEJ4 29674694

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218