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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 197122 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    139401 6u01:B (1.87) BS01 MG 4.3.3.7 GO:0005737 ... Q9PPB4 31678256
    139402 6u04:A (2.2) BS01 ZN ? N/A P55201
    P84243    		 31711755
    139403 6u04:A (2.2) BS02 ZN ? N/A P55201
    P84243    		 31711755
    139404 6u04:A (2.2) BS03 ZN ? N/A P55201
    P84243    		 31711755
    139405 6u04:A (2.2) BS04 ZN ? N/A P55201
    P84243    		 31711755
    139406 6u04:A (2.2) BS05 ZN ? N/A P55201
    P84243    		 31711755
    139407 6u07:A (1.76) BS01 MG ? N/A Q2YD82 32393818
    139408 6u08:A (2.491) BS01 ZN ? N/A A0A1V2VU04 32641830
    139409 6u08:C (2.491) BS01 ZN ? N/A A0A1V2VU04 32641830
    139410 6u08:E (2.491) BS01 ZN ? N/A A0A1V2VU04 32641830
    139411 6u08:G (2.491) BS01 ZN ? N/A A0A1V2VU04 32641830
    139412 6u0u:D (4.16) BS02 MG 3.6.5.- GO:0000226 ... P41351 31527277
    139413 6u0u:G (4.16) BS02 MG 3.6.5.- GO:0000226 ... P41351 31527277
    139414 6u0u:H (4.16) BS02 MG 3.6.5.- GO:0000226 ... P41351 31527277
    139415 6u0w:A (1.9) BS01 CA 3.1.31.1 GO:0003676 ... P00644 31692475
    139416 6u0x:A (1.86) BS01 CA 3.1.31.1 GO:0003676 ... P00644 31692475
    139417 6u0y:A (1.7) BS01 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139418 6u0y:A (1.7) BS02 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139419 6u0y:B (1.7) BS01 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139420 6u0y:B (1.7) BS02 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139421 6u0y:C (1.7) BS01 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139422 6u0y:C (1.7) BS02 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139423 6u0y:D (1.7) BS01 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139424 6u0y:D (1.7) BS02 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139425 6u0z:A (1.65) BS05 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139426 6u0z:A (1.65) BS06 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139427 6u10:A (1.4) BS01 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139428 6u10:A (1.4) BS02 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139429 6u13:A (1.52) BS02 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139430 6u13:A (1.52) BS03 ZN 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139431 6u19:B (-1.00) BS01 ZN 2.3.2.26 N/A Q05086 32157086
    139432 6u1a:A (1.09) BS01 CA N/A GO:0006091 ... N/A 32243936
    139433 6u1d:A (1.9) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139434 6u1d:A (1.9) BS04 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139435 6u1d:B (1.9) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139436 6u1d:B (1.9) BS04 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139437 6u1e:A (2.1) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139438 6u1e:A (2.1) BS04 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139439 6u1e:B (2.1) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139440 6u1e:B (2.1) BS04 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139441 6u1f:A (2.3) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139442 6u1f:A (2.3) BS04 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139443 6u1f:B (2.3) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139444 6u1f:B (2.3) BS04 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139445 6u1g:A (2.4) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139446 6u1g:A (2.4) BS04 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139447 6u1g:B (2.4) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139448 6u1g:B (2.4) BS04 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139449 6u1h:A (2.2) BS01 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139450 6u1h:C (2.2) BS01 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139451 6u1i:C (2.3) BS01 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139452 6u1j:C (2.2) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139453 6u1k:A (1.67) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139454 6u1k:B (1.67) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139455 6u1k:C (1.67) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139456 6u1k:D (1.67) BS03 MG 6.3.2.4 GO:0003824 ... Q5SHZ3 32335509
    139457 6u1m:A (1.61) BS01 FE 1.13.11.20 GO:0005506 ... P21816 N/A
    139458 6u1x:A (3.0) BS02 ZN 2.1.1.375
    2.7.7.48
    2.7.7.88
    3.6.1.-    		 GO:0001172 ... P03523 31914397
    139459 6u1x:A (3.0) BS03 ZN 2.1.1.375
    2.7.7.48
    2.7.7.88
    3.6.1.-    		 GO:0001172 ... P03523 31914397
    139460 6u22:A (1.42) BS02 CA 3.4.21.4 GO:0004175 ... P00760 32270580
    139461 6u2a:A (2.3) BS01 ZN 3.4.24.75 GO:0000920 ... Q9KN86 32393643
    139462 6u2f:A (2.94) BS02 CA 3.4.21.- GO:0004252 ... Q8NBP7 31962046
    139463 6u2g:A (2.886) BS02 MG 2.7.12.2 GO:0000165 ... Q02750 31988522
    139464 6u2g:B (2.886) BS01 MG 2.7.11.1 GO:0004672 ... P15056 31988522
    139465 6u2m:A (2.0) BS02 CA N/A GO:0003824 ... N/A 33795886
    139466 6u2m:A (2.0) BS03 CA N/A GO:0003824 ... N/A 33795886
    139467 6u2m:A (2.0) BS04 CA N/A GO:0003824 ... N/A 33795886
    139468 6u2m:A (2.0) BS05 CA N/A GO:0003824 ... N/A 33795886
    139469 6u2m:C (2.0) BS02 CA N/A GO:0003824 ... N/A 33795886
    139470 6u2m:C (2.0) BS03 CA N/A GO:0003824 ... N/A 33795886
    139471 6u2m:C (2.0) BS04 CA N/A GO:0003824 ... N/A 33795886
    139472 6u2m:C (2.0) BS05 CA N/A GO:0003824 ... N/A 33795886
    139473 6u2o:A (2.3) BS04 MG 2.7.7.7
    4.2.99.-
    4.2.99.18    		 GO:0001701 ... P06746 N/A
    139474 6u2z:A (2.38) BS02 CU 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139475 6u2z:A (2.38) BS03 CU 3.5.2.6 GO:0008270 ... B2FTM1 N/A
    139476 6u39:A (2.4) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139477 6u39:A (2.4) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139478 6u39:A (2.4) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139479 6u39:C (2.4) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139480 6u39:C (2.4) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139481 6u39:C (2.4) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139482 6u39:E (2.4) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139483 6u39:E (2.4) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139484 6u39:E (2.4) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139485 6u39:G (2.4) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139486 6u39:G (2.4) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139487 6u39:G (2.4) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139488 6u39:I (2.4) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139489 6u39:I (2.4) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139490 6u39:K (2.4) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139491 6u39:K (2.4) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139492 6u39:K (2.4) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139493 6u39:M (2.4) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139494 6u39:M (2.4) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139495 6u39:M (2.4) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139496 6u39:O (2.4) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139497 6u39:O (2.4) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139498 6u39:O (2.4) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139499 6u39:Q (2.4) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139500 6u39:Q (2.4) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139501 6u39:Q (2.4) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139502 6u39:S (2.4) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139503 6u39:S (2.4) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139504 6u39:S (2.4) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139505 6u3a:A (1.65) BS02 CA ? GO:0000086 ... P0DP23 32012279
    139506 6u3a:A (1.65) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139507 6u3a:A (1.65) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139508 6u3a:B (1.65) BS02 CA ? GO:0000086 ... P0DP23 32012279
    139509 6u3a:B (1.65) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139510 6u3a:B (1.65) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139511 6u3a:B (1.65) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139512 6u3b:A (1.7) BS01 CA ? GO:0000086 ... P0DP23 32012279
    139513 6u3b:A (1.7) BS02 CA ? GO:0000086 ... P0DP23 32012279
    139514 6u3b:A (1.7) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139515 6u3b:A (1.7) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139516 6u3b:B (1.7) BS01 CA ? N/A Q13936 32012279
    139517 6u3d:A (1.75) BS02 CA ? GO:0000086 ... P0DP23 32012279
    139518 6u3d:A (1.75) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139519 6u3d:A (1.75) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139520 6u3d:A (1.75) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139521 6u3d:B (1.75) BS02 CA ? GO:0000086 ... P0DP23 32012279
    139522 6u3d:B (1.75) BS03 CA ? GO:0000086 ... P0DP23 32012279
    139523 6u3d:B (1.75) BS04 CA ? GO:0000086 ... P0DP23 32012279
    139524 6u3d:B (1.75) BS05 CA ? GO:0000086 ... P0DP23 32012279
    139525 6u3i:A (2.9) BS02 CA 3.4.21.- GO:0004252 ... Q8NBP7 31962046
    139526 6u3j:A (2.25) BS02 MG 1.2.4.- GO:0002244 ... Q96HY7 32633484
    139527 6u3j:B (2.25) BS03 MG 1.2.4.- GO:0002244 ... Q96HY7 32633484
    139528 6u3u:A (2.287) BS01 ZN 3.2.2.22 GO:0016787 ... L0I969 31861375
    139529 6u42:2B (3.4) BS01 MG 3.6.5.- GO:0005200 ... P09204 31668805
    139530 6u42:2R (3.4) BS01 MG 3.6.5.- GO:0005200 ... P09204 31668805
    139531 6u42:A2 (3.4) BS02 MG 3.6.5.- GO:0005200 ... P09204 31668805
    139532 6u42:C7 (3.4) BS01 MG 3.6.5.- GO:0005200 ... P09204 31668805
    139533 6u42:F7 (3.4) BS01 MG 3.6.5.- GO:0005200 ... P09204 31668805
    139534 6u42:K5 (3.4) BS01 MG 3.6.5.- GO:0005200 ... P09204 31668805
    139535 6u42:X5 (3.4) BS01 MG 3.6.5.- GO:0005200 ... P09204 31668805
    139536 6u43:A (1.4) BS01 MG ? GO:0003746 ... A0A062V290 N/A
    139537 6u44:A (2.1) BS01 MG ? GO:0003746 ... A0A062V290 N/A
    139538 6u44:B (2.1) BS01 MG ? GO:0003746 ... A0A062V290 N/A
    139539 6u45:A (2.35) BS01 MG ? GO:0003746 ... A0A062V290 N/A
    139540 6u45:B (2.35) BS01 MG ? GO:0003746 ... A0A062V290 N/A
    139541 6u4b:A (2.1) BS01 MG ? GO:0016757 ... Q48484 32152541
    139542 6u4l:A (1.911) BS01 FE 1.13.11.20 GO:0005506 ... P21816 32368901
    139543 6u4m:A (-1.00) BS01 ZN ? N/A P49023 31590942
    139544 6u4m:A (-1.00) BS02 ZN ? N/A P49023 31590942
    139545 6u4n:B (-1.00) BS01 ZN ? N/A P49023 31590942
    139546 6u4n:B (-1.00) BS02 ZN ? N/A P49023 31590942
    139547 6u4q:A (1.306) BS01 ZN 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 31794211
    139548 6u4s:A (2.49) BS01 FE 1.13.11.20 GO:0005506 ... P21816 32368901
    139549 6u4t:A (1.356) BS01 ZN 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 31794211
    139550 6u4v:A (2.3) BS01 FE 1.13.11.20 GO:0005506 ... P21816 32368901
    139551 6u5n:A (3.2) BS01 CA ? GO:0005886 ... O27564 32269335
    139552 6u5n:A (3.2) BS02 CA ? GO:0005886 ... O27564 32269335
    139553 6u5n:A (3.2) BS03 CA ? GO:0005886 ... O27564 32269335
    139554 6u5n:B (3.2) BS01 CA ? GO:0005886 ... O27564 32269335
    139555 6u5n:B (3.2) BS02 CA ? GO:0005886 ... O27564 32269335
    139556 6u5n:B (3.2) BS03 CA ? GO:0005886 ... O27564 32269335
    139557 6u5n:C (3.2) BS01 CA ? GO:0005886 ... O27564 32269335
    139558 6u5n:C (3.2) BS02 CA ? GO:0005886 ... O27564 32269335
    139559 6u5n:C (3.2) BS03 CA ? GO:0005886 ... O27564 32269335
    139560 6u5n:D (3.2) BS01 CA ? GO:0005886 ... O27564 32269335
    139561 6u5n:D (3.2) BS02 CA ? GO:0005886 ... O27564 32269335
    139562 6u5n:D (3.2) BS03 CA ? GO:0005886 ... O27564 32269335
    139563 6u5n:E (3.2) BS01 CA ? GO:0005886 ... O27564 32269335
    139564 6u5n:E (3.2) BS02 CA ? GO:0005886 ... O27564 32269335
    139565 6u5n:E (3.2) BS03 CA ? GO:0005886 ... O27564 32269335
    139566 6u5n:F (3.2) BS01 CA ? GO:0005886 ... O27564 32269335
    139567 6u5n:F (3.2) BS02 CA ? GO:0005886 ... O27564 32269335
    139568 6u5n:F (3.2) BS03 CA ? GO:0005886 ... O27564 32269335
    139569 6u5n:G (3.2) BS01 CA ? GO:0005886 ... O27564 32269335
    139570 6u5n:G (3.2) BS02 CA ? GO:0005886 ... O27564 32269335
    139571 6u5n:G (3.2) BS03 CA ? GO:0005886 ... O27564 32269335
    139572 6u5n:H (3.2) BS01 CA ? GO:0005886 ... O27564 32269335
    139573 6u5n:H (3.2) BS02 CA ? GO:0005886 ... O27564 32269335
    139574 6u5n:H (3.2) BS03 CA ? GO:0005886 ... O27564 32269335
    139575 6u5p:A (3.3) BS01 CA ? GO:0005886 ... O27564 32269335
    139576 6u5p:A (3.3) BS02 CA ? GO:0005886 ... O27564 32269335
    139577 6u5p:A (3.3) BS03 CA ? GO:0005886 ... O27564 32269335
    139578 6u5p:B (3.3) BS01 CA ? GO:0005886 ... O27564 32269335
    139579 6u5p:B (3.3) BS02 CA ? GO:0005886 ... O27564 32269335
    139580 6u5p:B (3.3) BS03 CA ? GO:0005886 ... O27564 32269335
    139581 6u5p:C (3.3) BS01 CA ? GO:0005886 ... O27564 32269335
    139582 6u5p:C (3.3) BS02 CA ? GO:0005886 ... O27564 32269335
    139583 6u5p:C (3.3) BS03 CA ? GO:0005886 ... O27564 32269335
    139584 6u5p:D (3.3) BS01 CA ? GO:0005886 ... O27564 32269335
    139585 6u5p:D (3.3) BS02 CA ? GO:0005886 ... O27564 32269335
    139586 6u5p:D (3.3) BS03 CA ? GO:0005886 ... O27564 32269335
    139587 6u5p:E (3.3) BS01 CA ? GO:0005886 ... O27564 32269335
    139588 6u5p:E (3.3) BS02 CA ? GO:0005886 ... O27564 32269335
    139589 6u5p:E (3.3) BS03 CA ? GO:0005886 ... O27564 32269335
    139590 6u5p:F (3.3) BS01 CA ? GO:0005886 ... O27564 32269335
    139591 6u5p:F (3.3) BS02 CA ? GO:0005886 ... O27564 32269335
    139592 6u5p:F (3.3) BS03 CA ? GO:0005886 ... O27564 32269335
    139593 6u5p:G (3.3) BS01 CA ? GO:0005886 ... O27564 32269335
    139594 6u5p:G (3.3) BS02 CA ? GO:0005886 ... O27564 32269335
    139595 6u5p:G (3.3) BS03 CA ? GO:0005886 ... O27564 32269335
    139596 6u5p:H (3.3) BS01 CA ? GO:0005886 ... O27564 32269335
    139597 6u5p:H (3.3) BS02 CA ? GO:0005886 ... O27564 32269335
    139598 6u5p:H (3.3) BS03 CA ? GO:0005886 ... O27564 32269335
    139599 6u5r:A (3.6) BS01 CA ? GO:0005886 ... O27564 32269335
    139600 6u5r:B (3.6) BS01 CA ? GO:0005886 ... O27564 32269335
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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