2wtv	A	2.4	BS01	ZZL	A	1	L139 G140 V147 K162 L194 Y212 A213 G216 L263 A273 D274 G276 V279	L15 G16 V23 K38 L70 Y88 A89 G92 L139 A149 D150 G152 V155	D256 K258 E260 N261 D274 T292	D132 K134 E136 N137 D150 T168	2.7.11.1	0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321		Ki=1.8nM	-logKd/Ki=8.74, Ki=1.8nM	IC50=34nM, Kd=6.5nM	O14965	20067443	1390 	KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPRGEVYKELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK
2wtv	B	2.4	BS01	ZZL	B	1	L139 K141 V147 K162 Y212 A213 G216 L263 A273 D274 V279	L14 K16 V22 K37 Y87 A88 G91 L138 A148 D149 V154	D256 K258 E260 N261 D274 T292	D131 K133 E135 N136 D149 T167	2.7.11.1	0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321		Ki=1.8nM		IC50=34nM, Kd=6.5nM	O14965	20067443	1390 	RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPRGEVYKELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK
2wtv	C	2.4	BS01	ZZL	C	1	L139 K141 V147 K162 Y212 A213 G216 L263 A273 D274 F275 V279	L14 K16 V22 K37 Y87 A88 G91 L138 A148 D149 F150 V154	D256 K258 E260 N261 D274 T292	D131 K133 E135 N136 D149 T167	2.7.11.1	0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321		Ki=1.8nM		IC50=34nM, Kd=6.5nM	O14965	20067443	1392 	RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPRGEVYKELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK
2wtv	D	2.4	BS01	ZZL	D	1	G140 K141 V147 L194 Y212 A213 G216 L263 A273 D274 G276 V279	G16 K17 V23 L70 Y88 A89 G92 L139 A149 D150 G152 V155	D256 K258 E260 N261 D274 T292	D132 K134 E136 N137 D150 T168	2.7.11.1	0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321		Ki=1.8nM		IC50=34nM, Kd=6.5nM	O14965	20067443	1390 	KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPRGEVYKELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK
2wtw	A	3.302	BS01	ZZL	A	1	R137 G140 V147 K162 L194 L210 Y212 A213 G216 L263 A273 D274	R10 G13 V20 K35 L67 L83 Y85 A86 G89 L136 A146 D147	D256 K258 E260 N261 D274 T292	D129 K131 E133 N134 D147 T159	2.7.11.1	0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321			-logKd/Ki=8.19, Kd=6.5nM	IC50=34nM, Kd=6.5nM	O14965	20067443	1390 	WALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPRGEVYKELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK
2x81	A	2.91	BS01	ZZL	A	1	R137 L139 G140 V147 A160 L210 Y212 A213 G216 N261 L263 A273	R11 L13 G14 V18 A31 L81 Y83 A84 G87 N132 L134 A144	D256 K258 E260 N261 T292	D127 K129 E131 N132 T146	2.7.11.1	0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321			-logKd/Ki=8.30, IC50=5nM	IC50=34nM, Kd=6.5nM	O14965	20426425	1389 	QWALEDFEIGRPLGFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS
5ia1	A	2.036	BS01	ZZL	A	1	I619 V627 A644 K646 Y694 M695 G698 L746 S756 D757	I15 V23 A34 K36 Y84 M85 G88 L136 S146 D147	D739 A741 R743 N744 D757 P780	D129 A131 R133 N134 D147 P153	2.7.10.1	0004672,0004713,0005524,0006468		Kd=530nM	-logKd/Ki=6.28, Kd=530nM	Kd=370nM	P29317	27768280	1001 	TTEIHPSCVTRQKVIGAGEFGEVYKGMLKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFD