2wou A 2.3 BS01 ZZF A 1 I211 A230 L260 L278 S280 D281 Y282 H283 G286 D290 L340 I14 A33 L63 L81 S83 D84 Y85 H86 G89 D93 L143 D333 K335 N338 D351 T375 D136 K138 N141 D154 T178 2.7.11.30 0004672,0004675,0005524,0006468,0007178,0016020 ic50=72nM -logKd/Ki=7.14, IC50=72nM EC50=22nM, IC50=72nM P36897 19736928 1500 GGTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLS