3pdc A 2.6 BS01 ZYI A 1 F265 D333 M337 T358 Y381 Y465 H523 W524 F42 D110 M114 T135 Y158 Y241 H299 W300 F265 H332 D333 W334 N357 N376 Y381 Y465 D495 H523 F42 H109 D110 W111 N134 N153 Y158 Y241 D271 H299 3.1.3.76,3.3.2.10 0003824 -logKd/Ki=7.49, IC50=32nM P34913 21302953 1 APLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARN 3pdc B 2.6 BS01 ZYI B 1 D333 Y381 L406 Y465 L498 H523 W524 D110 Y158 L183 Y241 L274 H299 W300 F265 H332 D333 W334 N357 N376 Y381 Y465 D495 H523 F42 H109 D110 W111 N134 N153 Y158 Y241 D271 H299 3.1.3.76,3.3.2.10 0003824 P34913 21302953 2 APLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARN