7mxa A 2.713 BS01 ZR4 A 1 P314 L315 L319 Y324 F327 G365 E392 K393 D419 M420 E435 C449 P298 L299 L303 Y308 F311 G349 E376 K377 D403 M404 E419 C433 2.1.1.320 0000387,0000785,0002039,0003714,0005515,0005634,0005654,0005694,0005737,0005794,0005829,0006325,0006338,0006353,0006355,0006479,0007088,0008168,0008327,0008469,0010468,0016274,0018216,0032259,0032922,0032991,0034709,0035097,0035243,0035246,0042054,0042118,0042802,0043021,0044020,0044027,0044877,0045596,0045892,0046982,0048026,0048511,0048714,0070372,0070888,0090161,0097421,0140938,1901796,1904992 IC50=1.000nM, Ki=0.020000nM O14744 34737197 701 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7mxg A 2.395 BS01 ZR4 A 1 Y324 G365 E392 K393 D419 T420 E435 L436 C449 Y312 G353 E380 K381 D407 T408 E423 L424 C437 2.1.1.320 0000387,0000785,0002039,0003714,0005515,0005634,0005654,0005694,0005737,0005794,0005829,0006325,0006338,0006353,0006355,0006479,0007088,0008168,0008327,0008469,0010468,0016274,0018216,0032259,0032922,0032991,0034709,0035097,0035243,0035246,0042054,0042118,0042802,0043021,0044020,0044027,0044877,0045596,0045892,0046982,0048026,0048511,0048714,0070372,0070888,0090161,0097421,0140938,1901796,1904992 IC50=1.000nM, Ki=0.020000nM O14744 34737197 701 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDTREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7mxg C 2.395 BS01 ZR4 C 1 Y324 F327 G365 E392 K393 D419 T420 E435 L436 C449 Y312 F315 G353 E380 K381 D407 T408 E423 L424 C437 2.1.1.320 0000387,0000785,0002039,0003714,0005515,0005634,0005654,0005694,0005737,0005794,0005829,0006325,0006338,0006353,0006355,0006479,0007088,0008168,0008327,0008469,0010468,0016274,0018216,0032259,0032922,0032991,0034709,0035097,0035243,0035246,0042054,0042118,0042802,0043021,0044020,0044027,0044877,0045596,0045892,0046982,0048026,0048511,0048714,0070372,0070888,0090161,0097421,0140938,1901796,1904992 IC50=1.000nM, Ki=0.020000nM O14744 34737197 701 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDTREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL