2jal A 1.9 BS01 YLL A 1 Q20 H121 E166 E351 W398 E405 W406 F414 Q18 H119 E164 E342 W389 E396 W397 F405 R77 H121 E166 V169 N293 Y295 E351 R75 H119 E164 V167 N286 Y288 E342 3.2.1.21 0004553,0005975,0008422,0016798,0030245,0102483 -logKd/Ki=4.82, Ki=15uM Q08638 17252125 1446 VKKFPEGFLWGVATASYQIEGSPLADGAGMSIWHTFSHTPGNVKNGDTGDVACDHYNRWKEDIEIIEKLGVKAYRFSISWPRILPEGTGRVNQKGLDFYNRIIDTLLEKGITPFVTIYHWDLPFALQLKGGWANREIADWFAEYSRVLFENFGDRVKNWITLNEPWVVAIVGHLYGVHAPGMRDIYVAFRAVHNLLRAHARAVKVFRETVKDGKIGIVFNNGYFEPASERAVRFMHQFNNYPLFLNPIYRGDYPELVLEFAREYLPENYKDDMSEIQEKIDFVGLNYYSGHLVKFDPDAKVSFVERDLPKTAMGWEIVPEGIYWILKKVKEEYNPPEVYITENGAAFDDVVSEDGRVHDQNRIDYLKAHIGQAWKAIQEGVPLKGYFVWSLLDNFEWAEGYSKRFGIVYVDYSTQKRIVKDSGYWYSNVVKNNGLE 2jal B 1.9 BS01 YLL B 1 Q20 H121 E166 E351 W398 E405 W406 F414 Q19 H120 E165 E350 W397 E404 W405 F413 R77 H121 E166 V169 N293 Y295 E351 R76 H120 E165 V168 N292 Y294 E350 3.2.1.21 0004553,0005975,0008422,0016798,0030245,0102483 Q08638 17252125 1446 NVKKFPEGFLWGVATASYQIEGSPLADGAGMSIWHTFSHTPGNVKNGDTGDVACDHYNRWKEDIEIIEKLGVKAYRFSISWPRILPEGTGRVNQKGLDFYNRIIDTLLEKGITPFVTIYHWDLPFALQLKGGWANREIADWFAEYSRVLFENFGDRVKNWITLNEPWVVAIVGHLYGVHAPGMRDIYVAFRAVHNLLRAHARAVKVFRETVKDGKIGIVFNNGYFEPASEKEEDIRAVRFMHQFNNYPLFLNPIYRGDYPELVLEFAREYLPENYKDDMSEIQEKIDFVGLNYYSGHLVKFDPDAPAKVSFVERDLPKTAMGWEIVPEGIYWILKKVKEEYNPPEVYITENGAAFDDVVSEDGRVHDQNRIDYLKAHIGQAWKAIQEGVPLKGYFVWSLLDNFEWAEGYSKRFGIVYVDYSTQKRIVKDSGYWYSNVVKNNGLE 6yoz AAA 1.88 BS02 YLL AAA 1 A145 Y147 D173 Q175 E197 D199 E202 W347 A145 Y147 D173 Q175 E197 D199 E202 W347 3.2.1.4 0004553,0005576,0005975,0008810,0016798,0030245 P56680 34458755 507 QKPGETKEVHPQLTTFRCTKRGGCKPATNFIVLDSLSHPIHRAEGLGPGGCGDWGNPPPKDVCPDVESCAKNCIMEGIPDYSQYGVTTNGTSLRLQHILPDGRVPSPRVYLLDKTKRRYEMLHLTGFEFTFDVDATKLPCGMNSALYLSEMHPTGAKSKYNPGGAYYGTGYCDAQCFVTPFINGLGNIEGKGSCCNEMDIWEANSRASHVAPHTCNKKGLYLCEGEECAFEGVCDKNGCGWNNYRVNVTDYYGRGEEFKVNTLKPFTVVTQFLANRRGKLEKIHRFYVQDGKVIESFYTNKEGVPYTNMIDDEFCEATGSRKYMELGATQGMGEALTRGMVLAMSIWWDQGGNMEWLDHGEAGPCAKGEGAPSNIVQVEPFPEVTYTNLRWGEIGSTYQE 6yoz BBB 1.88 BS02 YLL BBB 1 A145 Y147 D173 Q175 E197 D199 E202 W347 A145 Y147 D173 Q175 E197 D199 E202 W347 3.2.1.4 0004553,0005576,0005975,0008810,0016798,0030245 P56680 34458755 509 QKPGETKEVHPQLTTFRCTKRGGCKPATNFIVLDSLSHPIHRAEGLGPGGCGDWGNPPPKDVCPDVESCAKNCIMEGIPDYSQYGVTTNGTSLRLQHILPDGRVPSPRVYLLDKTKRRYEMLHLTGFEFTFDVDATKLPCGMNSALYLSEMHPTGAKSKYNPGGAYYGTGYCDAQCFVTPFINGLGNIEGKGSCCNEMDIWEANSRASHVAPHTCNKKGLYLCEGEECAFEGVCDKNGCGWNNYRVNVTDYYGRGEEFKVNTLKPFTVVTQFLANRRGKLEKIHRFYVQDGKVIESFYTNKEGVPYTNMIDDEFCEATGSRKYMELGATQGMGEALTRGMVLAMSIWWDQGGNMEWLDHGEAGPCAKGEGAPSNIVQVEPFPEVTYTNLRWGEIGSTY 8bqa AAA 1.67 BS03 YLL AAA 1 W28 H97 N131 E132 Y194 E220 A226 G228 W254 W28 H97 N131 E132 Y194 E220 A226 G228 W254 3.2.1.4 0000272,0004553,0005975 B3PCS3 38161374 403 MVAPLSVQGNKILANGQPASFSGMSLFWSNTEWGGEKYYNAQVVSWLKSDWNAKLVRAAMGVEDEGGYLTDPANKDRVTQVVDAAIANDMYVIIDWHSHNAHQYQSQAIAFFQEMARKYGANNHVIYEIYNEPLQVSWSNTIKPYAQAVIAAIRAIDPDNLIIVGTPTWSQDVDVAANDPITGYQNIAYTLHFYAGTHGQYLRDKAQTALNRGIALFVTEWGSVNANGDGAVANSETNAWVSFMKTNHISNANWALNDKVEGASALVPGASANGGWVNSQLTASGALAKSIISGWPSY 8bqb A 2.701 BS01 YLL A 1 H122 N168 E169 Y236 E265 H277 W304 S311 H115 N161 E162 Y229 E258 H270 W297 S304 3.2.1.4 0000272,0004553,0008810,0016798 B3PF55 38161374 401 TSGWWNAGDVPAFDKRQLSRQLPLIRVDGNRFVDEQGNVQIFRGVSISDPNKLAKDQHFNKKHFDVIRSWGTNVVRIPVHPSAWRERGVKGYLELLDQAITWNNELGMYTIIDWHSMGNLKSEMFQNSMYHTSKGETFDFWRRVSERYNGINSVAFYEIFNEPTVFSGRLGIVSWAEWKAINEEAITIIQAHNPNAISLVAGFNWAYDLREAAANPIERNNVAYVSHPYPQKVGAPYQANWERDFGFMADKYPVFATEIGYQLASDKGAHIPVIDDGSYGPRITDYFAKKGISWVAWVFDPDWSPQMIKSWDYEPTMQGEHFRKVMLKENK 8bqb B 2.701 BS01 YLL B 1 H122 M124 N168 E169 Y236 E265 H277 W304 S311 H114 M116 N160 E161 Y228 E257 H269 W296 S303 3.2.1.4 0000272,0004553,0008810,0016798 B3PF55 38161374 401 SGWWNAGDVPAFDKRQLSRQLPLIRVDGNRFVDEQGNVQIFRGVSISDPNKLAKDQHFNKKHFDVIRSWGTNVVRIPVHPSAWRERGVKGYLELLDQAITWNNELGMYTIIDWHSMGNLKSEMFQNSMYHTSKGETFDFWRRVSERYNGINSVAFYEIFNEPTVFSGRLGIVSWAEWKAINEEAITIIQAHNPNAISLVAGFNWAYDLREAAANPIERNNVAYVSHPYPQKVGAPYQANWERDFGFMADKYPVFATEIGYQLASDKGAHIPVIDDGSYGPRITDYFAKKGISWVAWVFDPDWSPQMIKSWDYEPTMQGEHFRKVMLKEN 8bqb C 2.701 BS02 YLL C 1 H122 N168 E169 Y236 E265 H277 W304 S311 H114 N160 E161 Y228 E257 H269 W296 S303 3.2.1.4 0000272,0004553,0008810,0016798 B3PF55 38161374 402 SGWWNAGDVPAFDKRQLSRQLPLIRVDGNRFVDEQGNVQIFRGVSISDPNKLAKDQHFNKKHFDVIRSWGTNVVRIPVHPSAWRERGVKGYLELLDQAITWNNELGMYTIIDWHSMGNLKSEMFQNSMYHTSKGETFDFWRRVSERYNGINSVAFYEIFNEPTVFSGRLGIVSWAEWKAINEEAITIIQAHNPNAISLVAGFNWAYDLREAAANPIERNNVAYVSHPYPQKVGAPYQANWERDFGFMADKYPVFATEIGYQLASDKGAHIPVIDDGSYGPRITDYFAKKGISWVAWVFDPDWSPQMIKSWDYEPTMQGEHFRKVMLKEN 8oz1 A 1.3 BS02 YLL A 1 H136 N182 E183 Y253 E318 W360 H113 N159 E160 Y230 E295 W337 3.2.1.4 0000272,0004553 B3PD52 38161374 803 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNEPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGAGAQ