2yit A 2.2 BS01 YIT A 1 L226 V234 K249 E273 E305 G307 L354 T367 D368 L16 V24 K39 E49 E81 G83 L130 T143 D144 D347 K349 N352 D368 T387 D123 K125 N128 D144 T163 2.7.11.1 0004672,0005524,0006468 ic50=0.29nM -logKd/Ki=9.54, IC50=0.29nM O96017 21907711 600 VYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKLNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQ