3bz3 A 2.2 BS01 YAM A 1 R426 I428 V436 A452 E500 L501 C502 G505 L553 D564 L567 S568 R13 I15 V23 A35 E83 L84 C85 G88 L136 D147 L150 S151 D546 A548 R550 N551 D564 D129 A131 R133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 ic50=1.5nM -logKd/Ki=8.82, IC50=1.5nM IC50=1.5nM Q05397 18339875 1 DYEIQRERIELGRCIGEGQFGDVHQGIYMSPLAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEE 5tob A 2.117 BS01 YAM A 1 L431 G432 E433 M502 E503 L504 Y505 G508 E509 R553 L556 L12 G13 E14 M75 E76 L77 Y78 G81 E82 R126 L129 D549 A551 R553 N554 D567 D122 A124 R126 N127 D140 2.7.10.2 0004672,0004713,0005524,0006468 ic50=13nM -logKd/Ki=8.82, IC50=1.5nM IC50=13nM Q14289 27876318 701 IAREDVVLNRILGEGFFGEVYEGVYTHKGEKINVAVKTCKDNKEKFMSEAVIMKNLDHPHIVKLIGIIEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDIA 5x4o A 2.05 BS01 YAM A 1 N21 R24 L25 N22 R25 L26 ? Kd=88uM -logKd/Ki=4.06, Kd=88uM Kd=88000nM P41182 28471657 801 LYFQGADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKASE 8xox A 1.9 BS01 YAM A 1 L431 G432 E433 V439 M502 E503 Y505 G508 E509 L15 G16 E17 V23 M86 E87 Y89 G92 E93 2.7.10.2 0004672,0004713,0005524,0006468 Q14289 701 QYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDIAME