3e9i A 2.2 BS01 XAH A 1 G207 E231 R253 H261 N262 F265 M267 E269 Y271 E411 H412 N414 F416 E418 G467 G199 E223 R245 H253 N254 F257 M259 E261 Y263 E403 H404 N406 F408 E410 G459 R253 E255 R260 H261 E411 N414 R470 R245 E247 R252 H253 E403 N406 R462 6.1.1.6 0000049,0000166,0000287,0003676,0004812,0004824,0005524,0005737,0005829,0006412,0006418,0006430,0016740,0046872 -logKd/Ki=6.22, Ki=0.6uM Q9RHV9 19174549 1001 ELNDQLRVRREKLKKIEELGVDPFGKRFERTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKVSSYEFLTKALRPLPEKDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVAGGAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGISTRHNPEFTMLELYEAYADFRDIMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIKEYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKEREQGNDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRH 3e9i B 2.2 BS02 XAH B 1 G207 E231 R253 H261 N262 F265 E269 Y271 E411 H412 N414 F416 E418 G465 G467 R470 G199 E223 R245 H253 N254 F257 E261 Y263 E403 H404 N406 F408 E410 G457 G459 R462 R253 E255 R260 H261 E411 N414 R470 R245 E247 R252 H253 E403 N406 R462 6.1.1.6 0000049,0000166,0000287,0003676,0004812,0004824,0005524,0005737,0005829,0006412,0006418,0006430,0016740,0046872 Q9RHV9 19174549 1101 ELNDQLRVRREKLKKIEELGVDPFGKRFERTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKVSSYEFLTKALRPLPEKDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVAGGAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGISTRHNPEFTMLELYEAYADFRDIMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIKEYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKEREQGNDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRH 3e9i C 2.2 BS01 XAH C 1 G207 E231 R253 H261 N262 F265 M267 E269 Y271 E411 N414 F416 E418 G465 G467 R470 G199 E223 R245 H253 N254 F257 M259 E261 Y263 E403 N406 F408 E410 G457 G459 R462 R253 E255 R260 H261 E411 N414 R470 R245 E247 R252 H253 E403 N406 R462 6.1.1.6 0000049,0000166,0000287,0003676,0004812,0004824,0005524,0005737,0005829,0006412,0006418,0006430,0016740,0046872 Q9RHV9 19174549 1201 ELNDQLRVRREKLKKIEELGVDPFGKRFERTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKVSSYEFLTKALRPLPEKDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVAGGAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGISTRHNPEFTMLELYEAYADFRDIMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIKEYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKEREQGNDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRH 3e9i D 2.2 BS02 XAH D 1 G207 E231 R253 H261 N262 F265 E269 E411 H412 N414 F416 E418 G465 G467 R470 G199 E223 R245 H253 N254 F257 E261 E403 H404 N406 F408 E410 G457 G459 R462 R253 E255 R260 H261 E411 N414 R470 R245 E247 R252 H253 E403 N406 R462 6.1.1.6 0000049,0000166,0000287,0003676,0004812,0004824,0005524,0005737,0005829,0006412,0006418,0006430,0016740,0046872 Q9RHV9 19174549 1301 ELNDQLRVRREKLKKIEELGVDPFGKRFERTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKVSSYEFLTKALRPLPEKDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVAGGAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGISTRHNPEFTMLELYEAYADFRDIMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIKEYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKEREQGNDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRH