4xg8 A 2.4 BS01 X8G A 1 L377 A400 M448 M450 A451 P455 R498 L501 D512 L12 A31 M74 M76 A77 P81 R124 L127 D138 D494 A496 R498 N499 D512 D120 A122 R124 N125 D138 2.7.10.2 0004672,0004713,0005524,0006468 ic50=1.9nM -logKd/Ki=8.72, IC50=1.9nM IC50=11.1nM P43405 27504936 700 DRKLLTLEDKELGSGGTVKKGYYQMVVKTVAVKILDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN 4xg8 C 2.4 BS01 X8G C 1 L377 G378 V385 A400 M448 M450 A451 G454 P455 R498 L501 D512 L14 G15 V20 A35 M78 M80 A81 G84 P85 R128 L131 D142 N499 D512 N129 D142 2.7.10.2 0004672,0004713,0005524,0006468 ic50=1.9nM IC50=11.1nM P43405 27504936 700 YLDRKLLTLEDKELGSGGTVKKGYYQMKKVVKTVAVKILKPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY