3w2r A 2.05 BS01 W2R A 1 F723 V726 A743 K745 M766 C775 L788 M790 M793 L844 T854 D855 F856 R858 F997 F26 V29 A46 K48 M69 C78 L91 M93 M96 L147 T157 D158 F159 R161 F277 D837 A839 R841 N842 D855 D140 A142 R144 N145 D158 2.7.10.1 0004672,0004713,0005524,0006468 -logKd/Ki=7.72, IC50=19nM IC50=6.9nM P00533 24900643 1101 APNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDESNFYRALMDEEDMDDVVDADEYL 3w2s A 1.9 BS01 W2R A 1 V726 A743 K745 M766 L788 T790 M793 R841 L844 T854 D855 F856 G857 V26 A43 K45 M66 L88 T90 M93 R141 L144 T154 D155 F156 G157 D837 A839 R841 N842 D855 D137 A139 R141 N142 D155 2.7.10.1 0004672,0004713,0005524,0006468 -logKd/Ki=8.16, IC50=6.9nM IC50=6.9nM P00533 24900643 1101 QALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIP