4qjm A 1.75 BS02 V1F A 1 N62 H64 N67 I91 Q92 H94 H96 H119 F131 L198 T199 T200 P201 N59 H61 N64 I88 Q89 H91 H93 H116 F127 L194 T195 T196 P197 H64 H94 H96 E106 H119 T199 H61 H91 H93 E103 H116 T195 4.2.1.1,4.2.1.69 0002009,0004064,0004089,0005515,0005737,0005829,0005886,0006730,0008270,0015670,0016829,0018820,0032230,0032849,0038166,0043209,0044070,0045177,0046872,0046903,0051453,0070050,0070062,2001150,2001225 Kd=6.7nM -logKd/Ki=8.17, Kd=6.7nM P00918 25758852 302 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4qjo A 1.8 BS02 V1F A 1 Q89 H91 H93 H117 A129 L197 T198 T199 P200 Q87 H89 H91 H115 A127 L195 T196 T197 P198 H66 H91 H93 E104 H117 T198 H64 H89 H91 E102 H115 T196 4.2.1.1 0004089,0008270 Kd=40nM -logKd/Ki=7.40, Kd=40nM O43570 25758852 303 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4qjo B 1.8 BS02 V1F B 1 N64 Q89 H91 H93 V119 A129 L197 T198 T199 P200 N62 Q87 H89 H91 V117 A127 L195 T196 T197 P198 H66 H91 H93 E104 H117 T198 H64 H89 H91 E102 H115 T196 4.2.1.1 0004089,0008270 Kd=40nM O43570 25758852 304 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFS 4qjo C 1.8 BS02 V1F C 1 H91 H93 H117 V119 A129 S130 L197 T198 T199 P201 H89 H91 H115 V117 A127 S128 L195 T196 T197 P199 H66 H91 H93 E104 H117 T198 H64 H89 H91 E102 H115 T196 4.2.1.1 0004089,0008270 Kd=40nM O43570 25758852 302 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4qjo D 1.8 BS02 V1F D 1 N64 Q89 H91 H93 H117 V119 A129 S133 L197 T198 T199 P200 N62 Q87 H89 H91 H115 V117 A127 S131 L195 T196 T197 P198 H66 H91 H93 E104 H117 T198 H64 H89 H91 E102 H115 T196 4.2.1.1 0004089,0008270 Kd=40nM O43570 25758852 302 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4qjp A 1.62 BS02 V1F A 1 H66 N69 Q94 H96 H121 V123 F133 L200 T201 V202 W211 H61 N64 Q89 H91 H116 V118 F128 L195 T196 V197 W206 H66 H96 H98 E108 H121 T201 H61 H91 H93 E103 H116 T196 4.2.1.1 0004089,0005515,0005737,0005829,0006730,0008270,0016829,0043209,0043231,0046872 Kd=2.5nM Q8N1Q1 25758852 303 SWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 4qjp B 1.62 BS02 V1F B 1 S64 H66 N69 H96 H121 V123 F133 L200 T201 V202 P204 S59 H61 N64 H91 H116 V118 F128 L195 T196 V197 P199 H66 H96 H98 E108 H121 T201 H61 H91 H93 E103 H116 T196 4.2.1.1 0004089,0005515,0005737,0005829,0006730,0008270,0016829,0043209,0043231,0046872 Kd=2.5nM -logKd/Ki=8.60, Kd=2.5nM Q8N1Q1 25758852 303 SWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH