3b99 A 2.5 BS02 U51 A 1 Q94 W272 N277 L336 I337 T338 Q74 W252 N257 L304 I305 T306 4.2.1.152,5.3.99.4 0001516,0004497,0005506,0005783,0005789,0008116,0016020,0016705,0016829,0016853,0020037,0046872,0106256 Kd=1.9uM F1RE08 18032380 700 RRTRRRNEPPLDKGMIPWLGHALEFGKDAAKFLTRMKEKHGDIFTVRAAGLYITVLLDSNCYDAVLSDVASLDQTSYAQVLMKRIFNMILPSHNPESEKKRAEMHFQGASLTQLSNSMQNNLRLLMTPSEMGLKTSEWKKDGLFNLCYSLLFKTGYLTVFGAENNNSAALTQIYEEFRRFDKLLPKLARTTVNKEEKQIASAAREKLWKWLTPSGLDRKPREQSWLGSYVKQLQDEGIDAEMQRRAMLLQLWVTQGNAGPAAFWVMGYLLTHPEALRAVREEIQNTPVFDSVLWETLRLTAAALITRDVTQDKKICLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFLNATEKKDFFKNGARVKYPSVPWGTEDNLCPGRHFAVHAIKELVFTILTRFDVELCDKNATVPLVDPSRYGFGILQPAGDLEIRYRIR 3b99 A 2.5 BS03 U51 A 2 A98 Q99 L101 M102 L110 H113 W272 A78 Q79 L81 M82 L90 H93 W252 4.2.1.152,5.3.99.4 0001516,0004497,0005506,0005783,0005789,0008116,0016020,0016705,0016829,0016853,0020037,0046872,0106256 Kd=1.9uM F1RE08 18032380 701 RRTRRRNEPPLDKGMIPWLGHALEFGKDAAKFLTRMKEKHGDIFTVRAAGLYITVLLDSNCYDAVLSDVASLDQTSYAQVLMKRIFNMILPSHNPESEKKRAEMHFQGASLTQLSNSMQNNLRLLMTPSEMGLKTSEWKKDGLFNLCYSLLFKTGYLTVFGAENNNSAALTQIYEEFRRFDKLLPKLARTTVNKEEKQIASAAREKLWKWLTPSGLDRKPREQSWLGSYVKQLQDEGIDAEMQRRAMLLQLWVTQGNAGPAAFWVMGYLLTHPEALRAVREEIQNTPVFDSVLWETLRLTAAALITRDVTQDKKICLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFLNATEKKDFFKNGARVKYPSVPWGTEDNLCPGRHFAVHAIKELVFTILTRFDVELCDKNATVPLVDPSRYGFGILQPAGDLEIRYRIR 3b99 A 2.5 BS04 U51 A 3 F45 A68 Y97 R104 L336 R362 C364 G462 F463 F25 A48 Y77 R84 L304 R330 C332 G428 F429 4.2.1.152,5.3.99.4 0001516,0004497,0005506,0005783,0005789,0008116,0016020,0016705,0016829,0016853,0020037,0046872,0106256 Kd=1.9uM F1RE08 18032380 702 RRTRRRNEPPLDKGMIPWLGHALEFGKDAAKFLTRMKEKHGDIFTVRAAGLYITVLLDSNCYDAVLSDVASLDQTSYAQVLMKRIFNMILPSHNPESEKKRAEMHFQGASLTQLSNSMQNNLRLLMTPSEMGLKTSEWKKDGLFNLCYSLLFKTGYLTVFGAENNNSAALTQIYEEFRRFDKLLPKLARTTVNKEEKQIASAAREKLWKWLTPSGLDRKPREQSWLGSYVKQLQDEGIDAEMQRRAMLLQLWVTQGNAGPAAFWVMGYLLTHPEALRAVREEIQNTPVFDSVLWETLRLTAAALITRDVTQDKKICLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFLNATEKKDFFKNGARVKYPSVPWGTEDNLCPGRHFAVHAIKELVFTILTRFDVELCDKNATVPLVDPSRYGFGILQPAGDLEIRYRIR 3b99 B 2.5 BS02 U51 B 1 Q94 A98 V273 N277 A335 I337 T338 G462 Q74 A78 V221 N225 A271 I273 T274 G398 4.2.1.152,5.3.99.4 0001516,0004497,0005506,0005783,0005789,0008116,0016020,0016705,0016829,0016853,0020037,0046872,0106256 Kd=1.9uM F1RE08 18032380 700 RRTRRRNEPPLDKGMIPWLGHALEFGKDAAKFLTRMKEKHGDIFTVRAAGLYITVLLDSNCYDAVLSDVASLDQTSYAQVLMKRIFNMILPSHNPESEKKRAEMHFQGASLTQLSNSMQNNLRLLMTPSEMWKKDGLFNLCYSLLFKTGYLTVFTQIYEEFRRFDKLLPKLARTEKQIASAAREKLWKWLTSWLGSYVKQLQDEGIDAEMQRRAMLLQLWVTQGNAGPAAFWVMGYLLTHPEALRAVREEIQNTPVFDSVLWETLRLTAAALITRDVTQDKKICLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFLNADRTEKKDFFKNGARVKYPSVPWGTEDNLCPGRHFAVHAIKELVFTILTRFDVELCDKNATVPLVDPSRYGFGILQPAGDLEIRYRIR 3b99 B 2.5 BS03 U51 B 2 L101 E118 W245 Y249 Q270 W272 L81 E98 W193 Y197 Q218 W220 4.2.1.152,5.3.99.4 0001516,0004497,0005506,0005783,0005789,0008116,0016020,0016705,0016829,0016853,0020037,0046872,0106256 Kd=1.9uM F1RE08 18032380 701 RRTRRRNEPPLDKGMIPWLGHALEFGKDAAKFLTRMKEKHGDIFTVRAAGLYITVLLDSNCYDAVLSDVASLDQTSYAQVLMKRIFNMILPSHNPESEKKRAEMHFQGASLTQLSNSMQNNLRLLMTPSEMWKKDGLFNLCYSLLFKTGYLTVFTQIYEEFRRFDKLLPKLARTEKQIASAAREKLWKWLTSWLGSYVKQLQDEGIDAEMQRRAMLLQLWVTQGNAGPAAFWVMGYLLTHPEALRAVREEIQNTPVFDSVLWETLRLTAAALITRDVTQDKKICLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFLNADRTEKKDFFKNGARVKYPSVPWGTEDNLCPGRHFAVHAIKELVFTILTRFDVELCDKNATVPLVDPSRYGFGILQPAGDLEIRYRIR 3b99 B 2.5 BS04 U51 B 3 F45 I73 Y97 R209 R362 G462 F463 F25 I53 Y77 R173 R298 G398 F399 4.2.1.152,5.3.99.4 0001516,0004497,0005506,0005783,0005789,0008116,0016020,0016705,0016829,0016853,0020037,0046872,0106256 Kd=1.9uM F1RE08 18032380 702 RRTRRRNEPPLDKGMIPWLGHALEFGKDAAKFLTRMKEKHGDIFTVRAAGLYITVLLDSNCYDAVLSDVASLDQTSYAQVLMKRIFNMILPSHNPESEKKRAEMHFQGASLTQLSNSMQNNLRLLMTPSEMWKKDGLFNLCYSLLFKTGYLTVFTQIYEEFRRFDKLLPKLARTEKQIASAAREKLWKWLTSWLGSYVKQLQDEGIDAEMQRRAMLLQLWVTQGNAGPAAFWVMGYLLTHPEALRAVREEIQNTPVFDSVLWETLRLTAAALITRDVTQDKKICLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFLNADRTEKKDFFKNGARVKYPSVPWGTEDNLCPGRHFAVHAIKELVFTILTRFDVELCDKNATVPLVDPSRYGFGILQPAGDLEIRYRIR