1n3z A 1.65 BS01 U3P A 1 K41 N44 T45 F120 K36 N39 T40 F115 H12 K41 H119 F120 D121 H12 K36 H114 F115 D116 4.6.1.18 0003676,0004519,0004522,0004540,0005576,0016829,0042802,0050830,0051607 -logKd/Ki=4.20, Ki=63.2uM Ki=63200nM P00669 12833549 125 KESAAAKFERQHMDSGSSNYCNLMMCCRKMTQGKCKPVNTFVHESLADVKAVCSQKKVTCKNGQTNCYQSKSTMRITDCRETGSSKYPNCAYKTTQVEKHIIVACGGKPSVPVHFDASV 1o0n A 1.5 BS01 U3P A 1 H12 K41 V43 N44 T45 H119 F120 H12 K41 V43 N44 T45 H119 F120 H12 K41 H119 F120 D121 H12 K41 H119 F120 D121 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 Ki=82uM -logKd/Ki=4.09, Ki=82uM Ki=78500nM P61823 14573867 1101 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 1o0n B 1.5 BS01 U3P B 1 H12 K41 N44 T45 H119 F120 H12 K41 N44 T45 H119 F120 H12 K41 H119 F120 D121 H12 K41 H119 F120 D121 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 Ki=82uM Ki=78500nM P61823 14573867 1201 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 1ucc A 1.77 BS01 U3P A 1 Q9 N71 V72 L73 F80 H83 K87 Q9 N71 V72 L73 F80 H83 K87 H34 W37 S44 E84 K87 H88 H34 W37 S44 E84 K87 H88 4.6.1.19 0003723,0004519,0004521,0005576,0006401,0016829,0033897 P23540 10964705 300 FDSFWFVQQWPPAVCSFQKSGSCPGSGLRTFTIHGLWPQQSGTSLTNCPGSPFDITKISHLQSQLNTLWPNVLRANNQQFWSHEWTKHGTCSESTFNQAAYFKLAVDMRNNYDIIGALRPHAAGPNGRTKSRQAIKGFLKAKFGKFPGLRCRTDPQTKVSYLVQVVACFAQDGSTLIDCTRDTCGANFIF 4rsk A 2.1 BS01 U3P A 1 H12 K41 N44 T45 H119 F120 H12 K41 N44 T45 H119 F120 H12 K41 H119 F120 D121 H12 K41 H119 F120 D121 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 Kd=47.4uM -logKd/Ki=4.32, Kd=47.4uM Ki=78500nM P61823 9860854 125 KETAAAAFEAQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACANGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 4wyz A 1.449 BS01 U3P A 1 H12 K41 N44 T45 F120 H13 K42 N45 T46 F121 H12 K41 H119 F120 D121 H13 K42 H120 F121 D122 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 Kd=50uM -logKd/Ki=4.30, Kd=50uM Ki=78500nM P61823 26655472 401 MKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVGCEGNPYVPVHFDASV 4wyz B 1.449 BS01 U3P B 1 H12 K41 N44 T45 H119 F120 D121 H12 K41 N44 T45 H119 F120 D121 H12 K41 H119 F120 D121 H12 K41 H119 F120 D121 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 Kd=50uM Ki=78500nM P61823 26655472 401 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVGCEGNPYVPVHFDASV 6wre A 2.0 BS03 U3P A 1 R30 T31 Q32 G358 G359 P360 R4 T5 Q6 G332 G333 P334 3.1.13.-,3.6.1.- 0000166,0000287,0003723,0003729,0004527,0005634,0006402,0008409,0034353,0046872,0050779,0071028,0090304,0110152,0110155 O70348 31777937 402 PSLRTQPSLYSGPFPFYRRPSELGCFSLDAQRQYHGDARALRYYSPPPINGPGPDFDLRDGYPDRYQPRDEEVQERLDHLLRWVLEHRNQLEGGPGWLAGATVTWRGHLTKLLTTPYERQEGWQLAASRFQGTLYLSEVETPAARAQRLARPPLLRELMYMGYKFEQYMCADKPGGSPDPSGEVNTNVAYCSVLRSRLGNHPLLFSGEVDCLNPQAPCTQPPSCYVELKTSKEMHSPGQWRSFYRHKLLKWWAQSFLPGVPHVVAGFRNPEGFVCSLKTFPTMEMFENVRNDREGWNPSVCMNFCAAFLSFAQSTVVQDDPRLVHLFSWEPGGPVTVSVHRDAPYAFLPSWYVETMTQ 6x4i A 1.85 BS01 U3P A 1 H235 G248 H250 K290 W333 T341 H236 G249 H251 K291 W334 T342 2.1.1.56,2.1.1.57,2.7.7.48,2.7.7.50,3.1.13.-,3.4.19.12,3.4.22.-,3.4.22.69,3.6.4.12,3.6.4.13,4.6.1.- P0DTD1 33564093 401 NMSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 6x4i B 1.85 BS01 U3P B 1 H235 G248 H250 K290 W333 T341 Y343 H236 G249 H251 K291 W334 T342 Y344 2.1.1.56,2.1.1.57,2.7.7.48,2.7.7.50,3.1.13.-,3.4.19.12,3.4.22.-,3.4.22.69,3.6.4.12,3.6.4.13,4.6.1.- P0DTD1 33564093 401 NMSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKL