2ewp A 2.3 BS01 TXF A 1 C269 A272 D273 E275 L309 V313 Y326 N346 F435 L440 E441 C37 A40 D41 E43 L77 V81 Y94 N114 F203 L208 E209 ? ic50=0.079uM -logKd/Ki=7.10, IC50=0.079uM IC50=77nM P62508 16307879 501 PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEA 2ewp B 2.3 BS01 TXF B 1 L268 C269 A272 D273 E275 W305 M306 L309 V313 Y326 L342 N346 H434 F435 L440 L36 C37 A40 D41 E43 W73 M74 L77 V81 Y94 L110 N114 H202 F203 L208 ? ic50=0.079uM IC50=77nM P62508 16307879 502 PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEA 2ewp C 2.3 BS01 TXF C 1 C269 A272 D273 E275 V313 Y326 N346 H434 F435 L440 C36 A39 D40 E42 V80 Y93 N113 H201 F202 L207 ? ic50=0.079uM IC50=77nM P62508 16307879 503 YNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEA 2ewp D 2.3 BS01 TXF D 1 C269 A272 D273 E275 L309 V313 Y326 L342 L345 N346 H434 F435 L440 C35 A38 D39 E41 L75 V79 Y92 L108 L111 N112 H200 F201 L206 ? ic50=0.079uM IC50=77nM P62508 16307879 504 NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 2ewp E 2.3 BS01 TXF E 1 C269 A272 D273 E275 L309 V313 Y326 L345 N346 I349 F435 L440 C33 A36 D37 E39 L73 V77 Y90 L109 N110 I113 F194 L199 ? ic50=0.079uM IC50=77nM P62508 16307879 505 IVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE