3sd0 A 2.7 BS01 TSK A 1 I62 F67 V70 A83 K85 L132 D133 Y134 V135 P136 L188 C199 D200 I28 F33 V36 A49 K51 L98 D99 Y100 V101 P102 L154 C165 D166 D181 K183 N186 D200 S219 D147 K149 N152 D166 S185 2.7.11.1,2.7.11.26 0004672,0005524,0006468 IC50=247nM P49841 400 SKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARI 3sd0 B 2.7 BS01 TSK B 1 I62 G63 F67 V70 K85 L132 D133 Y134 V135 P136 L188 C199 D200 I28 G29 F33 V36 K51 L98 D99 Y100 V101 P102 L154 C165 D166 D181 K183 N186 D200 S219 D147 K149 N152 D166 S185 2.7.11.1,2.7.11.26 0004672,0005524,0006468 IC50=247nM P49841 400 SKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR