1i33 A 3.0 BS01 TND A 1 G9 G11 D38 M39 S40 A90 Q91 R92 G9 G11 D38 M39 S40 A90 Q91 R92 C166 H194 C166 H194 1.2.1.12 0004365,0005829,0006006,0006096,0016491,0016620,0020015,0050661,0051287 -logKd/Ki=4.12, IC50=75uM Q27890 11371162 361 APIKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMSTNAEYFAYQMKHDTVHGRPKYTVEAVKSSPSVETADVLVVNGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKAEGHIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHVVSNASCTTNCLAPIVHVLTKENFGIETGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTKGKLTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKAAQTYMKGILGFTDEELVSADFINDNRSSVYDSKATLQNNLPGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKDAASS 1i33 B 3.0 BS01 TND A 1 V206 L208 V206 L208 C166 H194 C166 H194 1.2.1.12 0004365,0005829,0006006,0006096,0016491,0016620,0020015,0050661,0051287 -logKd/Ki=4.12, IC50=75uM Q27890 11371162 361 APIKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMSTNAEYFAYQMKHDTVHGRPKYTVEAVKSSPSVETADVLVVNGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKAEGHIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHVVSNASCTTNCLAPIVHVLTKENFGIETGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTKGKLTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKAAQTYMKGILGFTDEELVSADFINDNRSSVYDSKATLQNNLPGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKDAASS 1i33 B 3.0 BS02 TND B 1 G9 G11 D38 M39 S40 A90 Q91 R92 T111 L113 G9 G11 D38 M39 S40 A90 Q91 R92 T111 L113 C166 H194 C166 H194 1.2.1.12 0004365,0005829,0006006,0006096,0016491,0016620,0020015,0050661,0051287 -logKd/Ki=4.12, IC50=75uM Q27890 11371162 362 APIKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMSTNAEYFAYQMKHDTVHGRPKYTVEAVKSSPSVETADVLVVNGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKAEGHIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHVVSNASCTTNCLAPIVHVLTKENFGIETGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTKGKLTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKAAQTYMKGILGFTDEELVSADFINDNRSSVYDSKATLQNNLPGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKDAASS 1i33 C 3.0 BS01 TND C 1 G9 G11 D38 M39 S40 A90 Q91 R92 T111 G9 G11 D38 M39 S40 A90 Q91 R92 T111 C166 H194 C166 H194 1.2.1.12 0004365,0005829,0006006,0006096,0016491,0016620,0020015,0050661,0051287 Q27890 11371162 363 APIKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMSTNAEYFAYQMKHDTVHGRPKYTVEAVKSSPSVETADVLVVNGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKAEGHIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHVVSNASCTTNCLAPIVHVLTKENFGIETGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTKGKLTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKAAQTYMKGILGFTDEELVSADFINDNRSSVYDSKATLQNNLPGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKDAASS 1i33 D 3.0 BS01 TND C 1 V206 L208 V206 L208 C166 H194 C166 H194 1.2.1.12 0004365,0005829,0006006,0006096,0016491,0016620,0020015,0050661,0051287 Q27890 11371162 363 APIKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMSTNAEYFAYQMKHDTVHGRPKYTVEAVKSSPSVETADVLVVNGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKAEGHIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHVVSNASCTTNCLAPIVHVLTKENFGIETGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTKGKLTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKAAQTYMKGILGFTDEELVSADFINDNRSSVYDSKATLQNNLPGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKDAASS 1i33 D 3.0 BS02 TND D 1 G11 D38 M39 A90 R92 T111 L113 G11 D38 M39 A90 R92 T111 L113 C166 H194 C166 H194 1.2.1.12 0004365,0005829,0006006,0006096,0016491,0016620,0020015,0050661,0051287 Q27890 11371162 364 APIKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMSTNAEYFAYQMKHDTVHGRPKYTVEAVKSSPSVETADVLVVNGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKAEGHIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHVVSNASCTTNCLAPIVHVLTKENFGIETGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTKGKLTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKAAQTYMKGILGFTDEELVSADFINDNRSSVYDSKATLQNNLPGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKDAASS 1i33 E 3.0 BS01 TND E 1 G9 G11 D38 M39 S40 A90 Q91 R92 T111 L113 G9 G11 D38 M39 S40 A90 Q91 R92 T111 L113 C166 H194 C166 H194 1.2.1.12 0004365,0005829,0006006,0006096,0016491,0016620,0020015,0050661,0051287 Q27890 11371162 365 APIKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMSTNAEYFAYQMKHDTVHGRPKYTVEAVKSSPSVETADVLVVNGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKAEGHIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHVVSNASCTTNCLAPIVHVLTKENFGIETGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTKGKLTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKAAQTYMKGILGFTDEELVSADFINDNRSSVYDSKATLQNNLPGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKDAASS 1i33 F 3.0 BS01 TND F 1 N8 G9 G11 V37 D38 M39 S40 A90 Q91 T111 L113 N8 G9 G11 V37 D38 M39 S40 A90 Q91 T111 L113 C166 H194 C166 H194 1.2.1.12 0004365,0005829,0006006,0006096,0016491,0016620,0020015,0050661,0051287 Q27890 11371162 366 APIKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMSTNAEYFAYQMKHDTVHGRPKYTVEAVKSSPSVETADVLVVNGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKAEGHIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHVVSNASCTTNCLAPIVHVLTKENFGIETGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTKGKLTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKAAQTYMKGILGFTDEELVSADFINDNRSSVYDSKATLQNNLPGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKDAASS