1a28 A 1.8 BS01 STR A 1 L718 N719 Q725 M759 L797 Y890 C891 L37 N38 Q44 M78 L116 Y209 C210 ? Ki=5.1nM -logKd/Ki=8.29, Ki=5.1nM Ki=3.5nM, EC50=2.9nM, IC50=>10000nM P06401 9620806 1 QLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHK 1a28 B 1.8 BS01 STR B 1 L718 N719 Q725 M756 M759 Y890 C891 L36 N37 Q43 M74 M77 Y208 C209 ? Ki=5.1nM Ki=3.5nM, EC50=2.9nM, IC50=>10000nM P06401 9620806 2 LIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFH 1dbb H 2.7 BS01 STR H 1 W50 G95 D96 Y97 W50 G99 D100 Y101 ? -logKd/Ki=9.00, Kd=1nM P01868 8496956 229 QIQLVQSGPELKKPGETVKISCKASGYAFTNYGVNWVKEAPGKELKWMGWINIYTGEPTYVDDFKGRFAFSLETSASTAYLEINNLKNEDTATYFCTRGDYVNWYFDVWGAGTTVTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIVPR 1dbb L 2.7 BS01 STR H 1 H27D S91 V94 H31 S96 V99 -logKd/Ki=9.00, Kd=1nM 8496956 229 DVVMTQIPLSLPVNLGDQASISCRSSQSLIHSNGNTYLHWYLQKPGQSPKLLMYKVSNRFYGVPDRFSGSGSGTDFTLKISRVEAEDLGIYFCSQSSHVPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNR 1h60 A 1.6 BS02 STR A 1 T26 R142 H181 H184 Y186 Q241 Y351 T26 R142 H181 H184 Y186 Q241 Y351 T26 H181 H184 Y186 R233 Q241 T26 H181 H184 Y186 R233 Q241 ? 0000166,0005829,0010181,0016491 Kd=20uM -logKd/Ki=4.70, Kd=20uM P71278 11428899 500 SAEKLFTPLKVGAVTAPNRVFMAPLTRLRSIEPGDIPTPLMGEYYRQRASAGLIISEATQISAQAKGYAGAPGLHSPEQIAAWKKITAGVHAEDGRIAVQLWHTGRISHSSIQPGGQAPVSASALNANTRTSLRDENGNAIRVDTTTPRALELDEIPGIVNDFRQAVANAREAGFDLVELHSAHGYLLHQFLSPSSNQRTDQYGGSVENRARLVLEVVDAVCNEWSADRIGIRVSPIGTFQNVDNGPNEEADALYLIEELAKRGIAYLHMSETDLAGGKPYSEAFRQKVRERFHGVIIGAGAYTAEKAEDLIGKGLIDAVAFGRDYIANPDLVARLQKKAELNPQRPESFYGGGAEGYTDYPSL 1mrq A 1.59 BS02 STR A 1 Y24 L54 V128 I129 H222 W227 L306 L308 Y24 L54 V128 I129 H222 W227 L306 L308 D50 Y55 K84 H117 D50 Y55 K84 H117 1.1.1.-,1.1.1.112,1.1.1.149,1.1.1.209,1.1.1.210,1.1.1.357,1.1.1.51,1.1.1.53,1.1.1.62,1.3.1.20 0001523,0004032,0004033,0004303,0005515,0005737,0005829,0006629,0006693,0006805,0007586,0008206,0015721,0016491,0016655,0030283,0030299,0030855,0031406,0032052,0033703,0033764,0035410,0042448,0042574,0042632,0044597,0044598,0046683,0047006,0047023,0047024,0047042,0047044,0047045,0047086,0047115,0047718,0070062,0071395,2000379 Q04828 12899831 501 QDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 1w0f A 2.65 BS01 STR A 1 F213 D217 F219 F220 F189 D193 F195 F196 T309 F435 C442 T270 F396 C403 1.14.14.1,1.14.14.55,1.14.14.56,1.14.14.73 0002933,0004497,0005496,0005506,0005515,0005737,0005783,0005789,0006629,0006631,0006694,0006706,0006805,0008202,0008203,0008209,0008210,0008395,0008401,0009822,0016020,0016098,0016491,0016705,0016712,0019825,0019899,0020037,0030343,0034875,0036378,0042178,0042359,0042369,0042572,0042573,0042759,0043231,0046222,0046872,0050591,0050649,0062181,0062187,0062188,0062189,0070330,0070576,0070989,0101020,0101021,0102320 P08684 15256616 1499 YGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLVDFLQLMIDSQNALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 1ya3 A 2.34 BS01 STR A 1 L766 Q776 M807 F829 M845 F941 C942 L25 Q35 M66 F88 M104 F192 C193 ? IC50=14nM, Kd=0.390000nM P08235 15908963 1001 SPVMVLENIEPEIVYAGYDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLLSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFH 1ya3 B 2.34 BS01 STR B 1 L766 L769 N770 Q776 L810 L814 F829 M845 M852 F941 C942 T945 L22 L25 N26 Q32 L66 L70 F85 M101 M108 F189 C190 T193 ? IC50=14nM, Kd=0.390000nM P08235 15908963 2001 PVMVLENIEPEIVYADTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLLSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFH 1ya3 C 2.34 BS01 STR C 1 L769 N770 Q776 M807 L810 F829 M845 F941 C942 T945 L27 N28 Q34 M65 L68 F87 M103 F191 C192 T195 ? IC50=14nM, Kd=0.390000nM P08235 15908963 3001 SPVMVLENIEVYAGYDSDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLLSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFH 2aa5 A 2.2 BS01 STR A 1 L769 N770 Q776 M807 S810 M845 M852 F941 C942 L48 N49 Q55 M86 S89 M124 M131 F214 C215 ? IC50=14nM, Kd=0.390000nM P08235 15967794 301 ALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKCSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFH 2aa5 B 2.2 BS01 STR B 1 L769 N770 A773 Q776 M807 S810 F829 M845 F941 C942 L47 N48 A51 Q54 M85 S88 F107 M123 F214 C215 ? IC50=14nM, Kd=0.390000nM P08235 15967794 302 LVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFH 2aa6 A 1.95 BS01 STR A 1 L769 N770 Q776 M807 F829 M845 M852 F941 C942 T945 L48 N49 Q55 M86 F108 M124 M131 F219 C220 T223 ? -logKd/Ki=9.41, Kd=0.39nM IC50=14nM, Kd=0.390000nM P08235 15967794 401 ALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLLSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKCNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFH 2aa6 B 1.95 BS01 STR B 1 L769 N770 Q776 M807 L810 F829 M845 M852 F941 C942 T945 L48 N49 Q55 M86 L89 F108 M124 M131 F218 C219 T222 ? IC50=14nM, Kd=0.390000nM P08235 15967794 402 ALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLLSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFH 2aba A 1.05 BS02 STR A 1 T26 Y68 R142 H184 Y186 Q241 Y351 T24 Y66 R140 H182 Y184 Q239 Y349 T26 H181 H184 Y186 R233 Q241 T24 H179 H182 Y184 R231 Q239 1.7.99.- 0000166,0005829,0010181,0016491 Kd=0.7uM P71278 16156787 1500 EKLFTPLKVGAVTAPNRVFMAPLTRLRSIEPGDIPTPLMGEYYRQRASAGLIISEATQISAQAKGYAGAPGLHSPEQIAAWKKITAGVHAEDGRIAVQLWHTGRISHSSIQPGGQAPVSASALNANTRTSLRDENGNAIRVDTTTPRALELDEIPGIVNDFRQAVANAREAGFDLVELHSAHGYLLHQFLSPSSNQRTDQYGGSVENRARLVLEVVDAVCNEWSADRIGIRVSPIGTFQNVDNGPNEEADALYLIEELAKRGIAYLHMSETDLAGGKPYSEAFRQKVRERFHGVIIGAGAYTAEKAEDLIGKGLIDAVAFGRDYIANPDLVARLQKKAELNPQRPESFYGGGAEGYTDYPSL 2hzq A 1.8 BS01 STR A 1 T34 A44 Y46 N58 F89 Y98 W127 L129 T32 A42 Y44 N56 F87 Y96 W125 L127 ? 0000302,0001525,0005319,0005515,0005576,0005615,0005737,0005783,0006006,0006629,0006869,0006950,0007420,0008289,0010642,0014012,0015485,0022626,0030425,0042246,0042308,0043025,0048471,0048662,0048678,0051895,0060588,0070062,0071638,1900016,2000098,2000405 Kd~1uM P05090 17699160 300 FHLGKCPNPPVQENFDVNKYPGRWYEIEKIPTTFENGRCIQANYSLMENGKIKVLNQELRADGTVNQIEGEATPVNLTEPAKLEVKFSWFMPSAPYHILATDYENYALVYSCTSISQSFHVDFAWILARNVALPPETVDSLKNILTSNNIDVKKMTVTDQVNCPKL 2o5y H 2.85 BS01 STR H 1 N35 W50 A100A M100B N35 W50 A105 M106 18689687 249 QVQLVQSGPELKKPGETVKISCKASGYMFTNYGMNWVKQAPGKALKWMGWINPYTGESTFADDFKGRFAFFLETSATTAYLQINNLKNEDTATYFCARGTTIVWAMDYWGQGTSVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 3cot A 2.03 BS02 STR A 1 Y26 Y58 E120 Y132 W230 W314 Y25 Y57 E119 Y131 W229 W313 D53 Y58 K87 E120 D52 Y57 K86 E119 1.3.1.3 0004032,0004033,0005496,0005515,0005737,0005829,0006699,0006707,0007586,0008202,0008207,0008209,0016042,0016229,0016491,0030573,0047086,0047787 P51857 18407998 1501 DLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY 3cot B 2.03 BS02 STR B 1 Y26 Y58 E120 W230 W314 Y25 Y57 E119 W229 W313 D53 Y58 K87 E120 D52 Y57 K86 E119 1.3.1.3 0004032,0004033,0005496,0005515,0005737,0005829,0006699,0006707,0007586,0008202,0008207,0008209,0016042,0016229,0016491,0030573,0047086,0047787 P51857 18407998 1500 DLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY 4bb2 A 2.48 BS02 STR B 1 S19 R260 N264 S7 R243 N247 ? 0004867,0005615 -logKd/Ki=7.07, Kd~85nM Ki=42nM P08185 23300763 1384 HHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFALEMTMGNALFLDGSLELLESFSADIAHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLT 4bb2 B 2.48 BS01 STR B 1 F366 H368 W371 F16 H18 W21 ? -logKd/Ki=7.07, Kd~85nM Ki=42nM P08185 23300763 1384 KPIILRFNQPFIIMIFDHFTWSSLFLARVMNPV 4fn9 A 3.0 BS01 STR A 1 L34 N35 A38 Q41 M72 M75 M110 F206 C207 L36 N37 A40 Q43 M74 M77 M112 F208 C209 23166518 301 NAPSLISILQAIEPEVVYAGYDNTQPDTTNYLLSSLNRLAEKQLVSVVKWAKALPGFRNLHLDDQMTLIQYSWMGLMAFAMGWRSYKHTNGQMLYFAPDLIFNEQRMQQSAMYDLCQGMQQISQEFVRLQVTQEEFLCMKALLLLSTVPKEGLKSQASFDEMRMNYIKELNRAIAKKENNSAQNWQRFYQLTKLLDSMHDLVGGLLQFCFYTFVQSQALSVEFPEMLVEIISAQLPKVLAGMAKPLLFHK 4fn9 B 3.0 BS01 STR B 1 L31 L34 N35 Q41 M72 M75 M110 F206 T210 L33 L36 N37 Q43 M74 M77 M112 F208 T212 23166518 301 NAPSLISILQAIEPEVVYAGYDNTQPDTTNYLLSSLNRLAEKQLVSVVKWAKALPGFRNLHLDDQMTLIQYSWMGLMAFAMGWRSYKHTNGQMLYFAPDLIFNEQRMQQSAMYDLCQGMQQISQEFVRLQVTQEEFLCMKALLLLSTVPKEGLKSQASFDEMRMNYIKELNRAIAKKENNSAQNWQRFYQLTKLLDSMHDLVGGLLQFCFYTFVQSQALSVEFPEMLVEIISAQLPKVLAGMAKPLLFH 4j6c A 1.9 BS01 STR A 1 M84 F179 A240 V291 M81 F176 A237 V288 S181 A244 E247 T248 T249 V291 C357 P358 G359 E366 Q398 S178 A241 E244 T245 T246 V288 C354 P355 G356 E363 Q395 ? 0004497,0005506,0016705,0020037,0046872 Q5YNS8 25372679 501 CPHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYATDGETPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4j6c B 1.9 BS03 STR B 1 M84 F179 A240 A244 V291 L294 M80 F175 A236 A240 V287 L290 S181 A244 E247 T248 T249 V291 C357 P358 G359 E366 Q398 S177 A240 E243 T244 T245 V287 C353 P354 G355 E362 Q394 ? 0004497,0005506,0016705,0020037,0046872 Q5YNS8 25372679 503 PHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYATDGETPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4l1w A 2.2 BS02 STR A 1 Y24 V128 I129 W227 L308 Y26 V130 I131 W229 L310 D50 Y55 K84 H117 D52 Y57 K86 H119 1.-.-.-,1.1.1.112,1.1.1.209,1.1.1.357,1.1.1.53,1.1.1.62,1.3.1.20 0004032,0004303,0005737,0005829,0006693,0007186,0007586,0008202,0008284,0016491,0016655,0030855,0031406,0032052,0042448,0044597,0044598,0047023,0047044,0047086,0047115,0047718,0051897,0071395,0071799 P52895 24434280 402 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4l1w B 2.2 BS02 STR B 1 Y24 I129 W227 L308 Y26 I131 W229 L310 D50 Y55 K84 H117 D52 Y57 K86 H119 1.-.-.-,1.1.1.112,1.1.1.209,1.1.1.357,1.1.1.53,1.1.1.62,1.3.1.20 0004032,0004303,0005737,0005829,0006693,0007186,0007586,0008202,0008284,0016491,0016655,0030855,0031406,0032052,0042448,0044597,0044598,0047023,0047044,0047086,0047115,0047718,0051897,0071395,0071799 P52895 24434280 402 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4l1x A 2.0 BS02 STR A 1 Y24 V128 H222 W227 L308 Y26 V130 H224 W229 L310 D50 Y55 K84 H117 D52 Y57 K86 H119 1.-.-.-,1.1.1.112,1.1.1.209,1.1.1.357,1.1.1.53,1.1.1.62,1.3.1.20 0004032,0004303,0005737,0005829,0006693,0007186,0007586,0008202,0008284,0016491,0016655,0030855,0031406,0032052,0042448,0044597,0044598,0047023,0047044,0047086,0047115,0047718,0051897,0071395,0071799 P52895 24434280 402 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4l1x B 2.0 BS02 STR B 1 Y24 V128 I129 H222 W227 L308 Y26 V130 I131 H224 W229 L310 D50 Y55 K84 H117 D52 Y57 K86 H119 1.-.-.-,1.1.1.112,1.1.1.209,1.1.1.357,1.1.1.53,1.1.1.62,1.3.1.20 0004032,0004303,0005737,0005829,0006693,0007186,0007586,0008202,0008284,0016491,0016655,0030855,0031406,0032052,0042448,0044597,0044598,0047023,0047044,0047086,0047115,0047718,0051897,0071395,0071799 P52895 24434280 402 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4ltw A 2.045 BS01 STR A 1 L34 N35 Q41 M72 M79 F206 C207 L37 N38 Q44 M75 M82 F209 C210 24260475 301 SNAPSLISILQAIEPEVVYAGYDNTQPDTTNYLLSSLNRLAEKQLVSVVKWAKALPGFRNLHLDDQMTLIQYSWMGLMAFAMGWRSYKHTNGQMLYFAPDLIFNEQRMQQSAMYDLCQGMQQISQEFVRLQVTQEEFLCMKALLLLSTVPKEGLKSQASFDEMRMNYIKELNRAIAKKENNSAQNWQRFYQLTKLLDSMHDLVGGLLQFCFYTFVQSQALSVEFPEMLVEIISAQLPKVLAGMAKPLLFHK 4nkx A 2.794 BS02 STR A 1 N202 D298 G301 A302 T306 V483 N172 D260 G263 A264 T268 V445 T306 F435 C442 T268 F397 C404 1.14.14.19,1.14.14.32 0004497,0004508,0005506,0005783,0005789,0006694,0006702,0006704,0007548,0008202,0008395,0016020,0016705,0016829,0019825,0020037,0030424,0042445,0042446,0042448,0043025,0046872 P05093 25301938 601 LLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDILSNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQA 4nkx B 2.794 BS02 STR B 1 A113 N202 D298 G301 V483 A83 N172 D263 G266 V448 T306 F435 C442 T271 F400 C407 1.14.14.19,1.14.14.32 0004497,0004508,0005506,0005783,0005789,0006694,0006702,0006704,0007548,0008202,0008395,0016020,0016705,0016829,0019825,0020037,0030424,0042445,0042446,0042448,0043025,0046872 P05093 25301938 601 LLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDILSNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNGQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQ 4nkx C 2.794 BS02 STR C 1 N202 V483 N172 V449 T306 F435 C442 T272 F401 C408 1.14.14.19,1.14.14.32 0004497,0004508,0005506,0005783,0005789,0006694,0006702,0006704,0007548,0008202,0008395,0016020,0016705,0016829,0019825,0020037,0030424,0042445,0042446,0042448,0043025,0046872 P05093 25301938 601 LLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDILSNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNGDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQ 4nkx D 2.794 BS02 STR D 1 N202 I206 D298 V483 N172 I176 D263 V448 T306 F435 C442 T271 F400 C407 1.14.14.19,1.14.14.32 0004497,0004508,0005506,0005783,0005789,0006694,0006702,0006704,0007548,0008202,0008395,0016020,0016705,0016829,0019825,0020037,0030424,0042445,0042446,0042448,0043025,0046872 P05093 25301938 601 LLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDILSNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQ 4r21 A 2.7 BS02 STR A 1 F121 G301 I371 F69 G240 I310 T306 F433 C440 T245 F364 C371 ? 0004497,0005506,0016705,0020037 A7U483 25533464 601 NLPPHLLFTQLSSQYGPLFGLYAGPHLTLVVSEIGLVREVLLQRGREFAGRPKMVTTDLLTQGGKDIAFADYSPLWKNHRRLVHSSFTLFGEGSNKLQTIVQEAADSLCEELQACRGQSSDLSVVLMRAVTNVICRLVFSSSYQPSDPELQTVIQYNDGIVQTIARGGLVDIKDLKRLKECVSIRDQLLYKKLLEHKKSLTPGEPRDLLDALLIGQQRGSGGADDITEDHVLMTAAEAFGAGVETTSTTLLWTIAFLLHHPQLQERVQAELDECVGVDRPPCLSDRPHLPLLDAVLCEVMRIRPVSPILIPHVAMQDTSLGGHSVPKGTRVLVNMWAIHHDPKHWDQPEQFNPERFLESSFLPFGAGPRVCVGESLARIELFLFVSRPLQRFSFSCPSLPDLQGRFGVVLQPERYTVTVTPR 4r21 B 2.7 BS02 STR B 1 F121 I212 G301 A302 S367 I371 F69 I160 G237 A238 S303 I307 T306 F433 C440 T242 F363 C370 ? 0004497,0005506,0016705,0020037 A7U483 25533464 601 NLPPHLLFTQLSSQYGPLFGLYAGPHLTLVVSEIGLVREVLLQRGREFAGRPKMVTTDLLTQGGKDIAFADYSPLWKNHRRLVHSSFTLFGEGSNKLQTIVQEAADSLCEELQACRGQSSDLSVVLMRAVTNVICRLVFSSSYQPSDPELQTVIQYNDGIVQTIARGGNKDLKRLKECVSIRDQLLYKKLLEHKKSLTPGEPRDLLDALLIGQQRGSGGADDITEDHVLMTAAEAFGAGVETTSTTLLWTIAFLLHHPQLQERVQAELDECVGVDRPPCLSDRPHLPLLDAVLCEVMRIRPVSPILIPHVAMQDTSLGGHSVPKGTRVLVNMWAIHHDPKHWDQPEQFNPERFLEPQSSFLPFGAGPRVCVGESLARIELFLFVSRPLQRFSFSCPSEASLPDLQGRFGVVLQPERYTVTVTP 4y8w A 2.64 BS02 STR A 1 V101 S109 V198 L199 W202 R234 D288 G292 L364 V73 S81 V170 L171 W174 R206 D251 G255 L321 T296 F422 C429 T259 F377 C384 1.14.14.16 0004497,0004509,0005496,0005506,0005783,0005789,0006694,0006704,0006705,0008202,0008395,0016020,0016125,0016705,0020037,0042445,0046872,0103069,0106309 P08686 25855791 604 KLPPLAPGFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDKIKDDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAIEKRDHIVEMQLRQHKESLVAGQWRDMMDYMLQGVAQLLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALPSLQPLPHCSVILKMQPFQVRLQPRG 4y8w B 2.64 BS02 STR B 1 V101 S109 V198 L199 W202 R234 D288 G292 V360 L364 V73 S81 V170 L171 W174 R206 D252 G256 V316 L320 T296 F422 C429 T260 F378 C385 1.14.14.16 0004497,0004509,0005496,0005506,0005783,0005789,0006694,0006704,0006705,0008202,0008395,0016020,0016125,0016705,0020037,0042445,0046872,0103069,0106309 P08686 25855791 603 KLPPLAPGFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDKIKDDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAIEKRDHIVEMQLRQHKESLVAGQWRDMMDYMLQGVAQQLLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALPSLQPLPHCSVILKMQPFQVRLQPR 4y8w C 2.64 BS02 STR C 1 V101 S109 V198 L199 W202 R234 D288 G292 V360 L364 V73 S81 V170 L171 W174 R206 D252 G256 V317 L321 T296 F422 C429 T260 F379 C386 1.14.14.16 0004497,0004509,0005496,0005506,0005783,0005789,0006694,0006704,0006705,0008202,0008395,0016020,0016125,0016705,0020037,0042445,0046872,0103069,0106309 P08686 25855791 603 KLPPLAPGFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDKIKDDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAIEKRDHIVEMQLRQHKESLVAGQWRDMMDYMLQGVAGQLLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHESRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALPSLQPLPHCSVILKMQPFQVRLQPRG 5a1p A 2.5 BS02 STR A 1 F213 D217 F219 F220 F188 D192 F194 F195 T309 F435 C442 T277 F403 C410 1.14.14.1,1.14.14.55,1.14.14.56,1.14.14.73 0002933,0004497,0005496,0005506,0005515,0005737,0005783,0005789,0006629,0006631,0006694,0006706,0006805,0008202,0008203,0008209,0008210,0008395,0008401,0009822,0016020,0016098,0016491,0016705,0016712,0019825,0019899,0020037,0030343,0034875,0036378,0042178,0042359,0042369,0042572,0042573,0042759,0043231,0046222,0046872,0050591,0050649,0062181,0062187,0062188,0062189,0070330,0070576,0070989,0101020,0101021,0102320 P08684 26066995 1600 GTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTRVDFLQLMIDSQNSSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 5a1r A 2.45 BS01 STR A 1 F213 D217 F219 F220 F188 D192 F194 F195 T309 F435 C442 T274 F400 C407 1.14.14.1,1.14.14.55,1.14.14.56,1.14.14.73 0002933,0004497,0005496,0005506,0005515,0005737,0005783,0005789,0006629,0006631,0006694,0006706,0006805,0008202,0008203,0008209,0008210,0008395,0008401,0009822,0016020,0016098,0016491,0016705,0016712,0019825,0019899,0020037,0030343,0034875,0036378,0042178,0042359,0042369,0042572,0042573,0042759,0043231,0046222,0046872,0050591,0050649,0062181,0062187,0062188,0062189,0070330,0070576,0070989,0101020,0101021,0102320 P08684 26066995 600 GTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLERVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 5lur A 2.7 BS01 STR A 1 M14 H16 W70 F72 T77 F79 W97 N118 M13 H15 W65 F67 T72 F74 W92 N113 ? 0009374 P02701 201 RKCSLTGKWTNRMNHNMTIGAVNSRGEFTGTYIATVNEIKESPLHGTQNTINKRTQPTFGFTVNWKFSESTTVFTGQCFIDRNGKEVLKTMWLLRSSVNDIGDDWKATRVGYNIFTRL 5lur B 2.7 BS01 STR B 1 M14 H16 W70 F79 W97 N118 M12 H14 W63 F72 W88 N109 ? 0009374 P02701 201 KCSLTGKWTNRMNHNMTIGAVNSRGEFTGTYIATVEIKESPLHGTQNTINKRTQPTFGFTVNWKFSESTTVFTGQCFIDGKEVLKTMWLLRSSVNDIGDDWKATRVGYNIFTRL 5mlm A 2.563 BS01 STR A 1 K147 M150 F153 I156 N205 M215 A243 F343 A346 V347 I350 P351 C352 K122 M125 F128 I131 N180 M190 A218 F318 A321 V322 I325 P326 C327 1.1.1.145 0000166,0003854,0016491,0016627 D6N9X1 30287897 401 SSVALIVGVTGIVGNSLAEILPLADTPSGPWKVYGVARRPRPAWNEDNPINYIRCDISDPKDTQEKLSPLTDITHVFYVTWANRSTEVERCEANGKMLKNVLDVVIPNCPDLKHISLQTGRKHYMGPFELIGKIETHDPPFTEDLPRLKFDNFYYTQEDLLFEEVEKKEGLTWSVHRPGNIFGFSPYSMMNLVGTLCVYAAICKHEGKVLRFPGCKAAWDGYSDCSDADLIAEHHIWAAVDPYAKNEAFNVSNGDVFKWKHFWKVLAEQFGVECGEYEEGENLKLQDLMKGKEPVWEEIVRENGLASTNLEDVAVWWFSDAVLDIPCPLDSMNKSKEHGFLGFRNSKNSFISWIDKAKAYKIVP 6f88 A 1.75 BS02 STR A 1 F64 S225 N276 F63 S224 N275 R160 E232 T233 C340 V341 G342 R159 E231 T232 C339 V340 G341 1.14.15.19 0004497,0005506,0016705,0020037,0046872 A9FDB7 29509407 502 DFPLANLFFVPSEDATAFGRRLRAAAQQAPIVFDTAFGMPILLRKSHITTAYRDTATFSTRMFQAGILNGGLAAMQGDEHARMRRVYNMFFLPRAVSQYEERFVRPISEQVVDRLAGKPRVDLLEDFAMELPRRVIGELFGFPAEKLHETDERVRAMLRGLVRMHDPAAVAESQRAYGETLGLITEVVERESRDTSDTLLGEILRTLKAEHMDTIEASRQIVLSLILGGYETTSWLVANTIHALLAHPDTLARVRQDPSLLPAAIEEGMRWCPSNFGVLRMVERDVRLDDQALSAGTVVCLAGIAGNYDETAYPSPEVYDIDRKPLPAANVFGGGAHFCVGAPLARMEARVGLQALLARFPGLRAVPEERPSFMYGAKDSVAHGPDKLPVLLHH 6f88 B 1.75 BS02 STR B 1 S225 N276 S225 N276 R160 E232 T233 C340 V341 G342 R160 E232 T233 C340 V341 G342 1.14.15.19 0004497,0005506,0016705,0020037,0046872 A9FDB7 29509407 502 MDFPLANLFFVPSEDATAFGRRLRAAAQQAPIVFDTAFGMPILLRKSHITTAYRDTATFSTRMFQAGILNGGLAAMQGDEHARMRRVYNMFFLPRAVSQYEERFVRPISEQVVDRLAGKPRVDLLEDFAMELPRRVIGELFGFPAEKLHETDERVRAMLRGLVRMHDPAAVAESQRAYGETLGLITEVVERESRDTSDTLLGEILRTLKAEHMDTIEASRQIVLSLILGGYETTSWLVANTIHALLAHPDTLARVRQDPSLLPAAIEEGMRWCPSNFGVLRMVERDVRLDDQALSAGTVVCLAGIAGNYDETAYPSPEVYDIDRKPLPAANVFGGGAHFCVGAPLARMEARVGLQALLARFPGLRAVPEERPSFMYGAKDSVAHGPDKLPVLL 6f8c A 1.9 BS02 STR A 1 S225 G229 I276 F277 G278 S224 G228 I275 F276 G277 R160 E232 T233 C340 V341 G342 R159 E231 T232 C339 V340 G341 1.14.15.19 0004497,0005506,0016705,0020037,0046872 A9FDB7 29509407 502 DFPLANLFFVPSEDATAFGRRLRAAAQQAPIVFDTAFGMPILLRKSHITTAYRDTATFSTRMFQAGILNGGLAAMQGDEHARMRRVYNMFFLPRAVSQYEERFVRPISEQVVDRLAGKPRVDLLEDFAMELPRRVIGELFGFPAEKLHETDERVRAMLRGLVRMHDPAAVAESQRAYGETLGLITEVVERESRDTSDTLLGEILRTLKAEHMDTIEASRQIVLSLILGGYETTSWLVANTIHALLAHPDTLARVRQDPSLLPAAIEEGMRWCPSIFGVLRMVERDVRLDDQALSAGTVVCLAGIAGNYDETAYPSPEVYDIDRKPLPAANVFGGGAHFCVGAPLARMEARVGLQALLARFPGLRAVPEERPSFMYGAKDSVAHGPDKLPVLLHH 6f8c B 1.9 BS02 STR B 1 S225 G229 F277 G278 S225 G229 F277 G278 R160 E232 T233 C340 V341 G342 R160 E232 T233 C340 V341 G342 1.14.15.19 0004497,0005506,0016705,0020037,0046872 A9FDB7 29509407 502 MDFPLANLFFVPSEDATAFGRRLRAAAQQAPIVFDTAFGMPILLRKSHITTAYRDTATFSTRMFQAGILNGGLAAMQGDEHARMRRVYNMFFLPRAVSQYEERFVRPISEQVVDRLAGKPRVDLLEDFAMELPRRVIGELFGFPAEKLHETDERVRAMLRGLVRMHDPAAVAESQRAYGETLGLITEVVERESRDTSDTLLGEILRTLKAEHMDTIEASRQIVLSLILGGYETTSWLVANTIHALLAHPDTLARVRQDPSLLPAAIEEGMRWCPSIFGVLRMVERDVRLDDQALSAGTVVCLAGIAGNYDETAYPSPEVYDIDRKPLPAANVFGGGAHFCVGAPLARMEARVGLQALLARFPGLRAVPEERPSFMYGAKDSVAHGPDKLPVLLH 6gsd A 2.7 BS01 STR A 1 R146 K147 F153 N205 M215 V347 I350 C352 R121 K122 F128 N180 M190 V322 I325 C327 1.1.1.145 0000166,0003854,0016491,0016627 D6N9X1 30287897 401 SSVALIVGVTGIVGNSLAEILPLADTPSGPWKVYGVARRPRPAWNEDNPINYIRCDISDPKDTQEKLSPLTDITHVFYVTWANRSTEVERCEANGKMLKNVLDVVIPNCPDLKHISLQTGRKHYVGPFELIGKIETHDPPFTEDLPRLKFDNFYYTQEDLLFEEVEKKEGLTWSVHRPGNIFGFSPYSMMNLVGTLCVYAAICKHEGKVLRFPGCKAAWDGYSDCSDADLIAEHHIWAAVDPYAKNEAFNVSNGDVFKWKHFWKVLAEQFGVECGEYEEGENLKLQDLMKGKEPVWEEIVRENGLASTNLEDVAVWWFSDAVLDIPCPLDSMNKSKEHGFLGFRNSKNSFISWIDKAKAYKIVP 6hgk A 1.855 BS01 STR A 1 S28 V31 F252 R270 A274 S7 V10 F231 R249 A253 ? 0003677,0004867,0005515,0005576,0005615,0005634,0006953,0006954,0010466,0019216,0030277,0031093,0034774,0035578,0062023,0070062,0072562 P01011 31103428 401 VDRGLASANVDFAFSLYKQLVLKAPDKNVIFSPVSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVQLNYTGNASVFFILPDQDKMEEVEAMLSRETLARWGDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLL 6hgk B 1.855 BS01 STR A 1 H383 W386 H17 W20 ? P01011 31103428 401 RTIVRFNRPFLMIIVDHFTWSIFFMSKVTNPKQA 7raf A 1.551 BS02 STR A 1 L704 N705 Q711 F764 T877 L35 N36 Q42 F95 T206 1001 IPIFLSVLQSIEPEVVYAGYDNTQPDTSASLLTSLNELGERQLVRVVKWAKALPGFRNLHVDDQMTLIQYSWMGVMVFAMGWRSYKNVNSRMLYFAPDLVFNEQRMQKSTMYNLCVRMRHLSQEFVWLQVTQEEFLCMKALLLFSIIPVEGLKNQKYFDELRMNYIKELDRVISFQNPTSSSQRFYQLTKLLDSLQDLVRKLHQFTFDTFVQSQSLSVEFPEMMSEIISAQVPKILAGMVKPLLFH 8fw8 B 2.31 BS01 STR B 1 F95 F113 W136 I140 L170 F82 F100 W123 I127 L157 ? 0003677 P39897 38326294 301 KTKEHLMLAALETFYRKGIARTSLNEIAQAAGVTRGALYWHFKNKEDLFDALFQRICDDIENCIAQDAGGSWTVFRHTLLHFFERLQSNDIHYKFHNILFLKCEHTEQNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKETAVIFIKSTLDGLIWRWFSSGESFDLGKTAPRIIGIMMDNLENHPCLRR 8fw8 C 2.31 BS01 STR C 1 F95 W136 I140 L170 F73 W114 I118 L148 ? 0003677 P39897 38326294 301 HLMLAALETFYRKGIARTSLNEIAQAAGVTRGALYWHFKNKEDLFDALFQRICDDIENCGGSWTVFRHTLLHFFERLQSNDIHYKFHNILFLKCEHTEQNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKETAVIFIKSTLDGLIWRWFSSGESFDLGKTAPRIIGIMMDNLENHPCLRR 8fw8 D 2.31 BS01 STR D 1 F95 W136 I140 F75 W116 I120 ? 0003677 P39897 38326294 301 KTKEHLMLAALETFYRKGIARTSLNEIAQAAGVTRGALYWHFKNKEDLFDALFQRICDDIENCSWTVFRHTLLHFFERLQSNDIHYKFHNILFLKCEHTEQNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKETAVIFIKSTLDGLIWRWFSSGESFDLGKTAPRIIGIMMDNLENHPCLRR 8gl7 A 2.4 BS02 STR A 1 L704 N705 Q711 F764 F876 T877 L880 L35 N36 Q42 F95 F207 T208 L211 1001 IPIFLSVLQSIEPEVVYAGYDNTQPDTSASLLTSLNELGERQLVRVVKWAKALPGFRNLHVDDQMTLIQYSWMGVMVFAMGWRSYKNVNSRMLYFAPDLVFNEQRMQKSTMYNLCVRMRHLSQEFVWLQVTQEEFLCMKALLLFSIIPVEGLKNQKYFDELRMNYIKELDRVISFQGKNPTSSSQRFYQLTKLLDSLQPIVRKLHQFTFDLFVQSQSLSVEFPEMMSEIISAQVPKILAGMVKPLLFH 8w4b A 2.152 BS01 STR A 1 W86 M90 L92 Y100 F104 E169 T178 A182 Y203 W92 M96 L98 Y106 F110 E175 T184 A188 Y209 0005634,0005635,0005637,0005640,0005783,0005789,0006869,0016020,0031410 Q6DCU6 38965213 301 GRSVDTMALWLGLRAVLVVAGLAVLLQLIRGWLSSKSYVFNREEIARLAKEHSGLDYEVAFSKIIVELRKKHPGHILQDEDLQWVFVNAGGWMGSMCLLHASLTEYVLLFGTAVDTGGHSGRYWAEISDTILSGTFRQWKEGTTKSEIFYPGDTIVHEVGEATSVQWSSGTWMVEYGRGFIPSTLAFALADTIFSTQDFLTLFYTVKVYSKALLLEASTHLSQLG 8w4c A 2.676 BS01 STR A 1 W86 M90 Y100 F104 E169 T178 A182 Y203 W92 M96 Y106 F110 E175 T184 A188 Y209 0005634,0005635,0005637,0005640,0005783,0005789,0006869,0016020,0031410 Q6DCU6 38965213 301 GRSVDTMALWLGLRAVLVVAGLAVLLQLIRGWLSSKSYVFNREEIARLAKEHSGLDYEVAFSKIIVELRKKHPGHILQDEDLQWVFVNAGGWMGSMCLLHASLTEYVLLFGTAVDTGGHSGRYWAEISDTILSGTFRQWKEGTTKSEIFYPGDTIVHEVGEATSVQWSSGTWMVEYGRGFIPSTLAFALADTIFSTQDFLTLFYTVKVYSKALLLEASTHLSQLG