2qlq A 2.33 BS01 SR2 A 1 V281 A293 K295 T338 M341 C345 D348 L393 D404 V26 A38 K40 T69 M72 C76 D79 L124 D135 D386 R388 A390 N391 D404 D117 R119 A121 N122 D135 2.7.10.2 0004672,0004713,0005524,0006468 -logKd/Ki=6.63, IC50=236nM IC50=>27000nM P00523 18316192 1345 AKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLAQVMKKLRHEKLVQLYAVVSEPIYIVTEYMSKGCLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 2qlq A 2.33 BS02 SR2 A 2 C483 P484 E486 C487 E489 C195 P196 E198 C199 E201 D386 R388 A390 N391 D404 D117 R119 A121 N122 D135 2.7.10.2 0004672,0004713,0005524,0006468 -logKd/Ki=6.63, IC50=236nM IC50=>27000nM P00523 18316192 1483 AKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLAQVMKKLRHEKLVQLYAVVSEPIYIVTEYMSKGCLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 2qlq B 2.33 BS01 SR2 B 1 A293 K295 I336 T338 G344 C345 D348 A390 L393 D404 A37 K39 I66 T68 G74 C75 D78 A120 L123 D134 D386 R388 A390 N391 D404 D116 R118 A120 N121 D134 2.7.10.2 0004672,0004713,0005524,0006468 IC50=>27000nM P00523 18316192 1345 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGCLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 2qq7 A 2.38 BS01 SR2 A 1 A293 K295 E310 M338 M341 G344 C345 L347 D348 L393 D404 A36 K38 E42 M70 M73 G76 C77 L79 D80 L125 D136 D386 R388 A390 N391 D404 D118 R120 A122 N123 D136 2.7.10.2 0004672,0004713,0005524,0006468 -logKd/Ki=5.24, IC50=5.71uM IC50=>27000nM P00523 18316192 1345 KDAWEIPRESLRLEVKLGQGFGEVWMGTWNGTTRVAIKTLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVMEYMSKGCLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 2qq7 B 2.38 BS01 SR2 B 1 L273 A293 K295 M338 G344 C345 D348 A390 L393 F405 L16 A34 K36 M66 G72 C73 D76 A118 L121 F133 D386 R388 A390 N391 D404 D114 R116 A118 N119 D132 2.7.10.2 0004672,0004713,0005524,0006468 IC50=>27000nM P00523 18316192 1345 DAWEIPRESLRLEVKLGQGGEVWMGTWNGTTRVAIKTLKQVMKKLRHEKLVQLYAVVSEEPIYIVMEYMSKGCLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL