4hwk A 2.4 BS02 SFY A 1 S154 L155 F161 Y167 P197 S154 L155 F161 Y167 P197 1.1.1.153 0004033,0004757,0005654,0005737,0005739,0005829,0006729,0006809,0016491,0050661,0070062 ic50=82nM P35270 23704574 807 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD 4hwk B 2.4 BS02 SFY B 1 S154 L155 C156 F161 W164 Y167 P197 S154 L155 C156 F161 W164 Y167 P197 1.1.1.153 0004033,0004757,0005654,0005737,0005739,0005829,0006729,0006809,0016491,0050661,0070062 ic50=82nM P35270 23704574 806 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD 4hwk C 2.4 BS02 SFY C 1 S154 L155 F161 W164 Y167 P197 S154 L155 F161 W164 Y167 P197 1.1.1.153 0004033,0004757,0005654,0005737,0005739,0005829,0006729,0006809,0016491,0050661,0070062 ic50=82nM P35270 23704574 804 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD 4hwk D 2.4 BS02 SFY D 1 S154 L155 F161 W164 Y167 P197 S154 L155 F161 W164 Y167 P197 1.1.1.153 0004033,0004757,0005654,0005737,0005739,0005829,0006729,0006809,0016491,0050661,0070062 ic50=82nM P35270 23704574 803 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD 5r9p A 1.72 BS01 SFY A 1 A51 T106 M109 G110 S154 A47 T102 M105 G106 S150 D150 K152 N155 D168 T185 D146 K148 N151 D164 T181 2.7.11.24 0000077,0000165,0000902,0000922,0001502,0001525,0001649,0001890,0002021,0002062,0004672,0004674,0004707,0005515,0005524,0005634,0005654,0005737,0005739,0005829,0006006,0006355,0006357,0006366,0006468,0006915,0006974,0007178,0007519,0010628,0010831,0016301,0016310,0016607,0018105,0019395,0019899,0019903,0030278,0030316,0031098,0031281,0031663,0032495,0032496,0032735,0032868,0035331,0035556,0035924,0035994,0038066,0042307,0042770,0045648,0045663,0045944,0046323,0046326,0048010,0048273,0048863,0051146,0051403,0051525,0060045,0060348,0071222,0071223,0071356,0071479,0071493,0090090,0090336,0090400,0098586,0098978,0099179,0106310,1900015,1901741,2000379 P47811 32543856 401 RPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPP 5rf8 A 1.44 BS01 SFY A 1 V186 R188 T190 V186 R188 T190 2.1.1.56,2.1.1.57,2.7.7.48,2.7.7.50,3.1.13.-,3.4.19.12,3.4.22.-,3.4.22.69,3.6.4.12,3.6.4.13,4.6.1.- 0008233,0019082 P0DTD1 33028810 404 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVT 5rzb A 1.59 BS01 SFY A 1 C316 S318 L321 R331 A333 C210 S212 L215 R225 A227 ? 0005856,0008092 Q9Y2J2 401 PKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLL 6mwf A 1.75 BS02 SFY A 1 D10 H12 G35 H36 S37 H44 I59 F63 D65 F70 L78 D10 H12 G35 H36 S37 H44 I59 F63 D65 F70 L78 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 202 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 6mwf C 1.75 BS02 SFY C 1 D10 H12 G35 H36 S37 H44 F63 D11 H13 G36 H37 S38 H45 F64 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 201 SMDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 7b8d A 1.62 BS01 SFY A 1 Y129 T236 F268 L269 I291 V346 Y42 T149 F181 L182 I193 V248 3.1.1.98 0016787 Q6P988 35731924 508 DLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTGVLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTEAIRRGIRYWNGVVPERCRRQFQEGEEWNCFFGYKVYPTLRSPVFVVQWLFDEAQLTVDNVHLPVQEGLRLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHPLKGCPVHLVDSCPWPHCNPSCPT 7h6l C 1.33 BS01 SFY C 1 M9 D10 V33 Y142 C143 R144 M12 D13 V36 Y145 C146 R147 2.1.1.-,2.7.7.-,2.7.7.19,2.7.7.48,3.1.3.84,3.4.22.-,3.6.1.15,3.6.1.74,3.6.4.13 Q8JUX6 208 GAMAPSYRVKRMDIAKNDEECVVNAANPRGLPGDGVCKAVYKKWPESFKNSATPVGTAKTVMCGTYPVIHAVGPNFSNYTESEGDRELAAAYREVAKEVTRLGVNSVAIPLLSTGVYSGGKDRLTQSLNHLFTAMDSTDADVVIYCRDKEWEKKISEAIQMRT