2oc2 A 2.25 BS02 RX3 A 1 Q281 H353 A354 S355 A356 H383 E384 H387 F391 H410 E411 F457 K511 F512 H513 V518 Y520 Y523 Q242 H314 A315 S316 A317 H344 E345 H348 F352 H371 E372 F417 K471 F472 H473 V478 Y480 Y483 H353 A354 H383 E384 H387 E411 H513 Y523 H314 A315 H344 E345 H348 E372 H473 Y483 3.4.15.1 0006508,0008237,0008241,0016020 Ki=3nM -logKd/Ki=8.52, Ki=3nM Ki=3nM P12821 17439247 680 DEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTP 2x96 A 1.85 BS01 RX3 A 1 Q266 H337 A338 S339 A340 H367 E368 H371 F375 H394 E395 D399 F441 K495 H497 V502 Y504 Y507 Q250 H321 A322 S323 A324 H351 E352 H355 F359 H378 E379 D383 F425 K479 H481 V486 Y488 Y491 H337 A338 H367 E368 H371 E395 H497 Y507 H321 A322 H351 E352 H355 E379 H481 Y491 3.4.15.1 0006508,0008237,0008241,0016020 Ki=94uM -logKd/Ki=4.03, Ki=94uM Q10714 20488190 1615 ALVKEEIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWLDEYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSNKCVS