1cbr A 2.9 BS01 REA A 1 L120 R131 Y133 L120 R131 Y133 ? 0005501,0005737,0008289,0016918,0019841 -logKd/Ki=9.40, Kd=0.4nM Kd=>200nM P62965 7704533 200 PNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVRTTEINFKVGEGFEEETVDGRKCRSLPTWENENKIHCTQTLLEGDGPKTYWTRELANDELILTFGADDVVCTRIYVRE 1cbr B 2.9 BS01 REA B 1 L120 R131 Y133 L120 R131 Y133 ? 0005501,0005737,0008289,0016918,0019841 -logKd/Ki=9.40, Kd=0.4nM Kd=>200nM P62965 7704533 200 PNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVRTTEINFKVGEGFEEETVDGRKCRSLPTWENENKIHCTQTLLEGDGPKTYWTRELANDELILTFGADDVVCTRIYVRE 1cbs A 1.8 BS01 REA A 1 A32 T54 L121 R132 Y134 A32 T54 L121 R132 Y134 ? 0001972,0005501,0005504,0005515,0005634,0005654,0005737,0005783,0005829,0006355,0007165,0008289,0008544,0015908,0016918,0019841,0030332,0035115,0042573,0048672,0070062 P29373 7704533 200 PNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGELILTMTADDVVCTRVYVRE 1fem A 1.9 BS01 REA A 1 V61 M73 M88 Y90 L97 Q98 H104 V61 M73 M88 Y90 L97 Q98 H104 ? 0005501,0005576,0005615,0016918,0019841,0034632,0034633 P18902 7961949 184 ERDCRVSSFRVKENFDKARFAGTWYAMAKKDPEGLFLQDNIVAEFSVDENGHMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIIDTDYETFAVQYSCRLLNLDGTCADSYSFVFARDPSGFSPEVQKIVRQRQEELCLARQYRLIPHNGYCDG 1g5y B 2.0 BS01 REA B 1 Q275 L276 W305 R316 L326 A327 F438 F439 I442 Q45 L46 W75 R86 L96 A97 F208 F209 I212 ? 0003677,0003707,0005634,0006355,0008270 P19793 10970886 501 PVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPH 1g5y C 2.0 BS01 REA C 1 L309 F313 R316 L326 A327 F438 L79 F83 R86 L96 A97 F208 ? 0003677,0003707,0005634,0006355,0008270 P19793 10970886 502 PVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 1gx9 A 2.34 BS01 REA A 1 L39 K69 I71 F105 M107 Q120 L38 K68 I70 F104 M106 Q119 ? 0005515,0005576,0019841,0036041,0036094,0042802 P02754 12054801 1163 IVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVEELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI 1n4h A 2.1 BS02 REA A 1 Q21 C55 V96 M100 A135 Q21 C55 V96 M100 A135 ? 0003677,0004879,0005634,0006355 Kd=280nM -logKd/Ki=6.55, Ki=0.28uM P45446 12958591 500 TMSEIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLLEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPDIVNTLFPPLYKELFN 1rlb E 3.1 BS01 REA E 1 L35 L37 A57 M73 Q98 F135 L35 L37 A57 M73 Q98 F135 ? 0001654,0002639,0005501,0005515,0005576,0005615,0006094,0007507,0007601,0016918,0019841,0030277,0030324,0032024,0032526,0034632,0034633,0042572,0042593,0048562,0048706,0048738,0048807,0060044,0060059,0060065,0060068,0060157,0060347,0070062 P02753 7754382 176 ERDCRVSSFRVKENFDKARFAGTWYAMAKKDPEGLFLQDNIVAEFSVDENGHMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIIDTDYETFAVQYSCRLLNLDGTCADSYSFVFARDPSGFSPQVQKIVRQRQEELCLARQYRLIPHNGYC 1rlb F 3.1 BS01 REA F 1 L35 F36 L37 L63 M73 M88 Y90 Q98 F135 L35 F36 L37 L63 M73 M88 Y90 Q98 F135 ? 0001654,0002639,0005501,0005515,0005576,0005615,0006094,0007507,0007601,0016918,0019841,0030277,0030324,0032024,0032526,0034632,0034633,0042572,0042593,0048562,0048706,0048738,0048807,0060044,0060059,0060065,0060068,0060157,0060347,0070062 P02753 7754382 177 ERDCRVSSFRVKENFDKARFAGTWYAMAKKDPEGLFLQDNIVAEFSVDENGHMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIIDTDYETFAVQYSCRLLNLDGTCADSYSFVFARDPSGFSPQVQKIVRQRQEELCLARQYRLIPHNGYC 2acl A 2.8 BS01 REA A 1 A272 Q275 F313 R316 L326 A327 C432 A29 Q32 F70 R73 L83 A84 C189 ? 0003677,0003707,0005634,0006355,0008270 P19793 16107141 502 SANEDMPVERILEAELAVEDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 2acl C 2.8 BS01 REA C 1 A271 A272 F313 R316 L326 A327 C432 A28 A29 F70 R73 L83 A84 C189 ? 0003677,0003707,0005634,0006355,0008270 P19793 16107141 503 SANEDMPVERILEAELAVEDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 2acl E 2.8 BS01 REA E 1 A272 Q275 F313 R316 L326 A327 C432 A29 Q32 F70 R73 L83 A84 C189 ? 0003677,0003707,0005634,0006355,0008270 P19793 16107141 504 SANEDMPVERILEAELAVEDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 2acl G 2.8 BS01 REA G 1 A272 F313 R316 L326 A327 C432 A29 F70 R73 L83 A84 C189 ? 0003677,0003707,0005634,0006355,0008270 P19793 16107141 501 SANEDMPVERILEAELAVEDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 2fr3 A 1.48 BS01 REA A 1 A32 L121 R132 Y134 A32 L121 R132 Y134 ? 0001972,0005501,0005504,0005515,0005634,0005654,0005737,0005783,0005829,0006355,0007165,0008289,0008544,0015908,0016918,0019841,0030332,0035115,0042573,0048672,0070062 Kd=2nM -logKd/Ki=8.70, Kd=2.0nM P29373 16979656 300 PNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGELILTMTADDVVCTRVYVRE 2g78 A 1.7 BS01 REA A 1 F15 A32 T54 V58 L121 M123 K132 F15 A32 T54 V58 L121 M123 K132 ? 0001972,0005501,0005504,0005515,0005634,0005654,0005737,0005783,0005829,0006355,0007165,0008289,0008544,0015908,0016918,0019841,0030332,0035115,0042573,0048672,0070062 -logKd/Ki=6.92, Kd=120nM P29373 17447762 200 PNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGELILTMTADDVVCTKVFVRE 2lbd A 2.06 BS01 REA A 1 F230 C237 L271 M272 I275 F288 S289 G393 F49 C56 L90 M91 I94 F107 S108 G212 ? 0003677,0004879,0005634,0006355,0048384 P13631 7501014 500 LSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENP 2ve3 A 2.1 BS02 REA A 1 F29 W80 F182 F253 G319 G320 Q345 F21 W72 F174 F245 G311 G312 Q337 A254 E257 T258 L259 F384 C391 E400 A246 E249 T250 L251 F376 C383 E392 1.14.-.- 0004497,0005506,0016125,0016705,0020037,0046872 Kd<1uM Q59990 18512957 1445 NSLPIPPGDFGLPWLGETLNFLNDGDFGKKRQQQFGPIFKTRLFGKNVIFISGALANRFLFTKEQETFQATWPLSTRILLGPNALATQMGEIHRSRRKILYQAFLPRTLDSYLPKMDGIVQGYLEQWGKANEVIWYPQLRRMTFDVAATLFMGEKVSQNPQLFPWFETYIQGLFSLPIPLPNTLFGKSQRARALLLAELEKIIKARQQQPPSEEDALGILLAARDDNNQPLSLPELKDQILLLLFAGHETLTSALSSFCLLLGQHSDIRERVRQEQNKLQLSQELTAETLKKMPYLDQVLQEVLRLIPPVGGGFRELIQDCQFQGFHFPKGWLVSYQISQTHADPDLYPDPEKFDPERFTPDGSATHNPPFAHVPFGGGLRECLGKEFARLEMKLFATRLIQQFDWTLLPGQNLELVVTPSPRPKDNLRVKLHSL 2ve3 B 2.1 BS02 REA B 1 F29 W80 F182 F253 V318 G319 Q345 F20 W71 F170 F241 V302 G303 Q329 A254 E257 T258 L259 F384 C391 E400 A242 E245 T246 L247 F368 C375 E384 1.14.-.- 0004497,0005506,0016125,0016705,0020037,0046872 Kd<1uM Q59990 18512957 1445 SLPIPPGDFGLPWLGETLNFLNDGDFGKKRQQQFGPIFKTRLFGKNVIFISGALANRFLFTKEQETFQATWPLSTRILLGPNALATQMGEIHRSRRKILYQAFLPRTLDSYLPKMDGIVQGYLEQWGKANEVIWYPQLRRMTFDVAATLFMGEKNPQLFPWFETYIQGLFSLPIPLPNTLFGKSQRARALLLAELEKIIKARQQQPPSEEDALGILLAARDDNNQPLSLPELKDQILLLLFAGHETLTSALSSFCLLLGQHSDIRERVRQEQNKLELTAETLKKMPYLDQVLQEVLRLIPPVGGGFRELIQDCQFQGFHFPKGWLVSYQISQTHADPDLYPDPEKFDPERFTPDGSATHNPPFAHVPFGGGLRECLGKEFARLEMKLFATRLIQQFDWTLLPGQNLELVVTPSPRPKDNLRVKLHSL 3a9e B 2.75 BS02 REA B 1 F228 C235 L269 F286 S287 F52 C59 L93 F110 S111 ? 0003677,0004879,0005634,0006355,0048384 P10276 21152046 1 SYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLE 3cwk A 1.6 BS01 REA A 1 A32 V54 V58 R59 E121 K132 A32 V54 V58 R59 E121 K132 ? 0001972,0005501,0005504,0005515,0005634,0005654,0005737,0005783,0005829,0006355,0007165,0008289,0008544,0015908,0016918,0019841,0030332,0035115,0042573,0048672,0070062 Kd=250nM -logKd/Ki=6.60, Kd=250nM P29373 19018099 300 PNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKVSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTLELTNDGELIETMTADDVVCTKVFVRE 3fal A 2.36 BS01 REA A 1 I268 A271 Q275 F313 R316 A327 V342 C432 I22 A25 Q29 F67 R70 A81 V96 C186 ? 0003677,0003707,0005634,0006355,0008270 P19793 18800767 501 NEDMPVERILEAELAVDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLTFLMEMLEA 3fal C 2.36 BS01 REA C 1 I268 A271 A272 Q275 F313 R316 L326 A327 C432 I24 A27 A28 Q31 F69 R72 L82 A83 C188 ? 0003677,0003707,0005634,0006355,0008270 P19793 18800767 501 SANEDMPVERILEAELAVDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLTFLMEMLEA 3fc6 A 2.063 BS01 REA A 1 I268 A271 A272 F313 R316 L326 A327 C432 I24 A27 A28 F69 R72 L82 A83 C188 ? 0003677,0003707,0005634,0006355,0008270 P19793 19167885 501 SANEDMPVERILEAELAVDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLDTFLMEMLEA 3fc6 C 2.063 BS01 REA C 1 A272 F313 R316 L326 A327 C432 A30 F71 R74 L84 A85 C190 ? 0003677,0003707,0005634,0006355,0008270 P19793 19167885 501 SANEDMPVERILEAELAVEPDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEDTFLMEMLEA 4dm8 A 2.3 BS02 REA A 1 F230 L233 A234 L271 I272 F288 S289 L400 F53 L56 A57 L94 I95 F111 S112 L221 ? 0003677,0004879,0005634,0006355,0048384 P10826 22355136 501 ESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLE 4dm8 B 2.3 BS02 REA B 1 F1230 L1233 A1234 L1271 I1272 F1288 S1289 F1304 L1400 F51 L54 A55 L92 I93 F109 S110 F125 L221 ? 0003677,0004879,0005634,0006355,0048384 P10826 22355136 1501 YEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLEN 4tns A 1.33 BS01 REA A 1 K63 R68 R69 S71 M130 Q131 F134 S154 H157 K13 R18 R19 S21 M80 Q81 F84 S104 H107 H59 C113 Q131 S154 H157 H9 C63 Q81 S104 H107 5.2.1.8 0003755 Q13526 201 EPARVRCSHLLVKHSQSRRPSSWRQEQITRTQEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 5fhz A 2.9 BS02 REA A 1 G136 R139 F182 M186 W189 C313 C314 L471 G118 R121 F164 M168 W171 C295 C296 L453 N181 K204 E280 C314 E411 E488 N163 K186 E262 C296 E393 E470 1.2.1.36 0001758,0002072,0002138,0004029,0004030,0005737,0005829,0006629,0006915,0007626,0016491,0016620,0021768,0031076,0042472,0042572,0042573,0042574,0042803,0043065,0043584,0048048,0050885,0051289,0060013,0060166,0060324,0070062,0070324,0070384,0070403 P47895 27759097 602 ALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 5fhz B 2.9 BS02 REA B 1 L185 W189 Q304 L471 L164 W168 Q283 L438 N181 K204 E280 C314 E411 E488 N160 K183 E259 C293 E378 E455 1.2.1.36 0001758,0002072,0002138,0004029,0004030,0005737,0005829,0006629,0006915,0007626,0016491,0016620,0021768,0031076,0042472,0042572,0042573,0042574,0042803,0043065,0043584,0048048,0050885,0051289,0060013,0060166,0060324,0070062,0070324,0070384,0070403 P47895 27759097 602 RPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVFDVKTEQGPQIELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 5fhz C 2.9 BS02 REA C 1 G136 L185 W189 Q304 F308 L471 G117 L166 W170 Q285 F289 L452 N181 K204 E280 C314 E411 E488 N162 K185 E261 C295 E392 E469 1.2.1.36 0001758,0002072,0002138,0004029,0004030,0005737,0005829,0006629,0006915,0007626,0016491,0016620,0021768,0031076,0042472,0042572,0042573,0042574,0042803,0043065,0043584,0048048,0050885,0051289,0060013,0060166,0060324,0070062,0070324,0070384,0070403 P47895 27759097 602 LPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 5fhz D 2.9 BS02 REA D 1 R139 F182 M186 C313 C314 L471 R120 F163 M167 C294 C295 L452 N181 K204 E280 C314 E411 E488 N162 K185 E261 C295 E392 E469 1.2.1.36 0001758,0002072,0002138,0004029,0004030,0005737,0005829,0006629,0006915,0007626,0016491,0016620,0021768,0031076,0042472,0042572,0042573,0042574,0042803,0043065,0043584,0048048,0050885,0051289,0060013,0060166,0060324,0070062,0070324,0070384,0070403 P47895 27759097 602 LPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 5uan B 3.508 BS06 REA B 1 F221 A225 C228 L262 I266 F279 S280 F295 F121 A125 C128 L162 I166 F179 S180 F195 ? 0003677,0003700,0004879,0005634,0006355,0008270,0043565,0048384 P10826 29021580 503 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLE 6eu9 B 2.69 BS01 REA B 1 V356 F414 G428 F430 V40 F98 G112 F114 ? 0000978,0000981,0003677,0004879,0005634,0005667,0006355,0006357,0035259,0048384,0071376 A0A384E144 29492455 601 ELTEDEEEMVEKILKAHEETFPYLTDDDKYRLTQILWERVSELSTKAIANVVDFGKQVPVFTQLSTNDQITLLKAACLEIIILRLASRYDDKEDTMSFSNGLTLTQQQLEVGGFGTLTPTIFKFARSLVELSVDTAEYAMLSLICLISGDRSGLEHPEKVEQKQEPILETLKHYVRKRRPDSPHSFAKLLLKLTDLRSLSVKGAERVLQLRMEMPGELPPLILEMLD 6eu9 D 2.69 BS01 REA D 1 V356 L394 F414 L420 G428 V40 L78 F98 L104 G112 ? 0000978,0000981,0003677,0004879,0005634,0005667,0006355,0006357,0035259,0048384,0071376 A0A384E144 29492455 601 ELTEDEEEMVEKILKAHEETFPYLTDDDKYRLTQILWERVSELSTKAIANVVDFGKQVPVFTQLSTNDQITLLKAACLEIIILRLASRYDDKEDTMSFSNGLTLTQQQLEVGGFGTLTPTIFKFARSLVELSVDTAEYAMLSLICLISGDRSGLEHPEKVEQKQEPILETLKHYVRKRRPDSPHSFAKLLLKLTDLRSLSVKGAERVLQLRMEMPGELPPLILEMLD 7y42 A 3.45 BS01 REA A 1 Y365 Y369 F377 L513 Y225 Y229 F237 L371 ? 0016020,0019031,0019064,0039654,0046813,0055036,0075509 P0DTC2 35862773 1310 AYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVGVYFASSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCFTFEYVSQKNLREFVFFKIYSKHTPDLPQGFSALEVDLPIGINIAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPDQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTSQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDS 7y42 B 3.45 BS01 REA B 1 Y365 Y369 F377 L387 C432 L513 Y225 Y229 F237 L247 C292 L371 ? 0016020,0019031,0019064,0039654,0046813,0055036,0075509 P0DTC2 35862773 1310 AYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVGVYFASSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCFTFEYVSQKNLREFVFFKIYSKHTPDLPQGFSALEVDLPIGINIAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPDQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTSQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDS 7y42 D 3.45 BS01 REA D 1 L368 Y369 F374 F377 L387 F392 I434 L228 Y229 F234 F237 L247 F252 I294 ? 0016020,0019031,0019064,0039654,0046813,0055036,0075509 P0DTC2 35862773 1310 AYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVGVYFASSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCFTFEYVSQKNLREFVFFKIYSKHTPDLPQGFSALEVDLPIGINIAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPDQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTSQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDS