2oo8 X 2.2 BS01 RAJ X 1 A853 E872 L876 I886 I902 Y904 A905 H962 A981 D982 F983 A13 E29 L33 I43 I55 Y57 A58 H115 A134 D135 F136 N969 D982 N122 D135 2.7.10.1 0004672,0004713,0005524,0006468 ic50=1nM -logKd/Ki=9.00, IC50=1nM IC50=1nM Q02763 17350837 1 GQVLKARIRMDAAIKRMKEKDDHRDFAGELEVLCKLGHHPNIINLLGACEHYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGID 3be2 A 1.75 BS01 RAJ A 1 V848 A866 E885 T916 F918 C919 H1026 L1035 I1044 C1045 D1046 F1047 V34 A49 E68 T99 F101 C102 H159 L168 I177 C178 D179 F180 D1028 A1030 R1032 N1033 D1046 D161 A163 R165 N166 D179 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169 ic50=2nM -logKd/Ki=8.70, IC50=2nM IC50=2nM P35968 18324761 501 EHAERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDTCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHH