4wnu A 2.26 BS02 QDN A 1 F120 G212 L213 E216 Q244 F247 S304 F483 F75 G164 L165 E168 Q196 F199 S256 F435 T309 F436 C443 T261 F388 C395 1.14.14.- 0004497,0005506,0005737,0005739,0005783,0005789,0006631,0006805,0008202,0008203,0008210,0009804,0009820,0009822,0016020,0016098,0016491,0016705,0016712,0019369,0020037,0033076,0042178,0042572,0042759,0043231,0046872,0051100,0062187,0062188,0062189,0070989,0090350 IC50=10.0nM, Ki=30nM P10635 25555909 602 GKLPPGPNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 4wnu B 2.26 BS02 QDN B 1 F120 E216 Q244 F247 S304 F76 E172 Q200 F203 S260 T309 F436 C443 T265 F392 C399 1.14.14.- 0004497,0005506,0005737,0005739,0005783,0005789,0006631,0006805,0008202,0008203,0008210,0009804,0009820,0009822,0016020,0016098,0016491,0016705,0016712,0019369,0020037,0033076,0042178,0042572,0042759,0043231,0046872,0051100,0062187,0062188,0062189,0070989,0090350 IC50=10.0nM, Ki=30nM P10635 25555909 602 KLPPGPFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 4wnu C 2.26 BS03 QDN C 1 F120 L213 E216 Q244 F247 S304 F483 F75 L168 E171 Q199 F202 S259 F438 T309 F436 C443 T264 F391 C398 1.14.14.- 0004497,0005506,0005737,0005739,0005783,0005789,0006631,0006805,0008202,0008203,0008210,0009804,0009820,0009822,0016020,0016098,0016491,0016705,0016712,0019369,0020037,0033076,0042178,0042572,0042759,0043231,0046872,0051100,0062187,0062188,0062189,0070989,0090350 IC50=10.0nM, Ki=30nM P10635 25555909 602 GKLPPGPNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 4wnu D 2.26 BS02 QDN D 1 F120 G212 E216 Q244 F247 S304 F75 G165 E169 Q197 F200 S257 T309 F436 C443 T262 F389 C396 1.14.14.- 0004497,0005506,0005737,0005739,0005783,0005789,0006631,0006805,0008202,0008203,0008210,0009804,0009820,0009822,0016020,0016098,0016491,0016705,0016712,0019369,0020037,0033076,0042178,0042572,0042759,0043231,0046872,0051100,0062187,0062188,0062189,0070989,0090350 IC50=10.0nM, Ki=30nM P10635 25555909 602 LPPGPFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 6lqa B 3.3 BS01 QDN B 1 V405 T1417 S1710 V1763 V287 T787 S1080 V1133 ? 0001518,0002027,0003161,0003231,0003360,0005216,0005248,0005261,0005272,0005515,0005516,0005654,0005730,0005737,0005783,0005886,0005901,0006811,0006814,0009986,0010765,0014704,0014894,0016020,0016328,0017134,0019899,0019901,0019904,0021537,0021549,0030018,0030315,0030506,0031625,0034220,0034702,0035725,0042383,0042475,0044325,0045760,0048471,0050679,0050998,0051899,0055085,0060048,0060307,0060371,0060372,0060373,0070161,0071277,0086002,0086004,0086005,0086006,0086010,0086012,0086014,0086015,0086016,0086043,0086045,0086046,0086047,0086048,0086060,0086061,0086062,0086063,0086067,0086091,0097110,0098912,1902305 Q14524 33684260 2110 PIRRAAVKILVHSLFNMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARGFCLHAFTFLRDPWNWLDFSVIIMAYTTEFVDLGNVSALRTFRVLRALKTISVISGLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLFMGNLRHKCVRNFTALNGTNGSVEADGLVWESLDLYLSDPENYLLKNGTSDVLLCGNSSDAGTCPEGYRCLKAGENPDHGYTSFDSFAWAFLALFRLMTQDCWERLYQQTLRSAGKIYMIFFMLVIFLGSFYLVNLILAVVAMAYEEQNQATIAETEECCPLWMSIKQGVKLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSNLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWIETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSFSAGKVWWRLRKTCYHIVEHSWFETFIIFMILLSSGALAFEDIYLEERKTIKVLLEYADKMFTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSLVSLVANTLGFAEMGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFGRCINQTEGDLPLNYTIVNNKSQCESLNLTGELYWTKVKVNFDNVGAGYLALLQVATFKGWMDIMYAAVDSRGYEEQPQWEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINILAKINLLFVAIFTGECIVKLAALRHYYFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIISFLIVVNMYIAIILENFSVATEE