1a16 A 2.3 BS01 PRO A 1 H243 H350 E383 R404 H242 H349 E382 R403 D38 H243 D260 D271 H350 H354 H361 E383 Y387 R404 E406 D38 H242 D259 D270 H349 H353 H360 E382 Y386 R403 E405 3.4.11.9 0004177,0005515,0005737,0005829,0006508,0008235,0008237,0030145,0032991,0042802,0046872,0046914,0051289,0070006 P15034 9520390 441 SEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSLEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ 1e8k A 1.9 BS02 PRO A 1 R62 M68 Q70 F120 H133 R62 M68 Q70 F120 H133 R62 F67 Q70 N109 F120 L129 H133 R62 F67 Q70 N109 F120 L129 H133 5.2.1.8 0000413,0003755,0005515,0005634,0005737,0005739,0006457,0016018 P52011 11180378 1002 MSRSKVFFDITIGGKASGRIVMELYDDVVPKTAGNFRALCTGENGIGKSGKPLHFKGSKFHRIIPNFMIQGGDFTRGNGTGGESIYGEKFPDENFKEKHTGPGVLSMANAGPNTNGSQFFLCTVKTEWLDGKHVVFGRVVEGLDVVKAVESNGSQSGKPVKDCMIADCGQLK 1h2z A 1.65 BS01 PRO A 1 Y473 F476 A554 N555 W595 H680 Y473 F476 A554 N555 W595 H680 Y473 A554 D641 H680 Y473 A554 D641 H680 3.4.21.26 0004252,0005737,0005829,0006508,0008236,0070012 P23687 12202494 726 MLSFQYPDVYRDETAIQDYHGHKVCDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNAYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRHSPNYRLINIDFTDPEESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNTLQLHDLATGALLKIFPLEVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGANGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQNNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIDWIP 1h4t A 2.9 BS01 PRO A 1 T111 E113 W158 E160 F205 H230 S258 W259 G260 T98 E100 W145 E147 F192 H217 S245 W246 G247 E113 R142 H162 E100 R129 H149 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006412,0006418,0006433,0017101,0046872 Q5SM28 11399074 1478 KGLTPQSQDFSEWYLEVIQKAELADYGPVRGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSFLFSPELAVVTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMRTRPFLRTSEFLWQEGHTAHATREEAEEEVRRMLSIYARLAREYAAIPVIEGLKTEKEKFAGAVYTTTIEALMKDGKALQAGTSHYLGENFARAFDIKFQDRDLQVKYVHTTSWGLSWRFIGAIIMTHGDDRGLVLPPRLAPIQVVIVPIYKDESRERVLEAAQGLRQALLAQGLRVHLDDRDQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGGKETLPLAALPEALPGKLDAFHEELYRRALAFREDHTRKVDTYEAFKEAVQEGFALAFHCGDKACERLIQEETTATTRCVPFEAEPEEGFCVRCGRPSAYGKRVVFAKAY 1h4t B 2.9 BS01 PRO B 1 T111 E113 W158 F205 H230 S258 W259 G260 T98 E100 W145 F192 H217 S245 W246 G247 E113 R142 H162 E100 R129 H149 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006412,0006418,0006433,0017101,0046872 Q5SM28 11399074 1478 KGLTPQSQDFSEWYLEVIQKAELADYGPVRGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSFLFSPELAVVTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMRTRPFLRTSEFLWQEGHTAHATREEAEEEVRRMLSIYARLAREYAAIPVIEGLKTEKEKFAGAVYTTTIEALMKDGKALQAGTSHYLGENFARAFDIKFQDRDLQVKYVHTTSWGLSWRFIGAIIMTHGDDRGLVLPPRLAPIQVVIVPIYKDESRERVLEAAQGLRQALLAQGLRVHLDDRDQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGGKETLPLAALPEALPGKLDAFHEELYRRALAFREDHTRKVDTYEAFKEAVQEGFALAFHCGDKACERLIQEETTATTRCVPFEAEPEEGFCVRCGRPSAYGKRVVFAKAY 1h4t C 2.9 BS01 PRO C 1 T111 E113 W158 E160 F205 H230 S258 W259 G260 T98 E100 W145 E147 F192 H217 S245 W246 G247 E113 R142 H162 E100 R129 H149 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006412,0006418,0006433,0017101,0046872 Q5SM28 11399074 1478 KGLTPQSQDFSEWYLEVIQKAELADYGPVRGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSFLFSPELAVVTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMRTRPFLRTSEFLWQEGHTAHATREEAEEEVRRMLSIYARLAREYAAIPVIEGLKTEKEKFAGAVYTTTIEALMKDGKALQAGTSHYLGENFARAFDIKFQDRDLQVKYVHTTSWGLSWRFIGAIIMTHGDDRGLVLPPRLAPIQVVIVPIYKDESRERVLEAAQGLRQALLAQGLRVHLDDRDQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGGKETLPLAALPEALPGKLDAFHEELYRRALAFREDHTRKVDTYEAFKEAVQEGFALAFHCGDKACERLIQEETTATTRCVPFEAEPEEGFCVRCGRPSAYGKRVVFAKAY 1h4t D 2.9 BS01 PRO D 1 T111 E113 W158 E160 F205 H230 S258 W259 G260 T98 E100 W145 E147 F192 H217 S245 W246 G247 E113 R142 H162 E100 R129 H149 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006412,0006418,0006433,0017101,0046872 Q5SM28 11399074 1478 KGLTPQSQDFSEWYLEVIQKAELADYGPVRGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSFLFSPELAVVTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMRTRPFLRTSEFLWQEGHTAHATREEAEEEVRRMLSIYARLAREYAAIPVIEGLKTEKEKFAGAVYTTTIEALMKDGKALQAGTSHYLGENFARAFDIKFQDRDLQVKYVHTTSWGLSWRFIGAIIMTHGDDRGLVLPPRLAPIQVVIVPIYKDESRERVLEAAQGLRQALLAQGLRVHLDDRDQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGGKETLPLAALPEALPGKLDAFHEELYRRALAFREDHTRKVDTYEAFKEAVQEGFALAFHCGDKACERLIQEETTATTRCVPFEAEPEEGFCVRCGRPSAYGKRVVFAKAY 1o6f A 1.6 BS01 PRO A 1 Y473 F476 S554 N555 W595 Y473 F476 S554 N555 W595 Y473 S554 A641 H680 Y473 S554 A641 H680 3.4.21.26 0004252,0005737,0005829,0006508,0008236,0070012 P23687 12228249 726 MLSFQYPDVYRDETAIQDYHGHKVCDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNAYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRHSPNYRLINIDFTDPEESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNTLQLHDLATGALLKIFPLEVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLIKYSPLHNVKLPEADDIQYPSMLLLTADHADRVVPLHSLKFIATLQYIVGRSRKQNNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIDWIP 1o6g A 1.4 BS01 PRO A 1 Y473 F476 S554 N555 W595 H680 Y473 F476 S554 N555 W595 H680 Y473 S554 N641 H680 Y473 S554 N641 H680 3.4.21.26 0004252,0005737,0005829,0006508,0008236,0070012 P23687 12228249 726 MLSFQYPDVYRDETAIQDYHGHKVCDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNAYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCVEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRHSPNYRLINIDFTDPEESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNTLQLHDLATGALLKIFPLEVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLIKYSPLHNVKLPEADDIQYPSMLLLTADHNDRVVPLHSLKFIATLQYIVGRSRKQNNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIDWIP 1pin A 1.35 BS01 PRO A 1 L122 Q129 M130 L112 Q119 M120 H59 C113 Q131 S154 H157 H49 C103 Q121 S144 H147 5.2.1.8 0000413,0001666,0001932,0001934,0003755,0003774,0005515,0005634,0005654,0005737,0005829,0007088,0008013,0010468,0016607,0016859,0030182,0030496,0030512,0031434,0031647,0032091,0032092,0032465,0032794,0035307,0036064,0042177,0043547,0045944,0046785,0048156,0050808,0050815,0050816,0050821,0051219,0060255,0060392,0070373,0080090,0090263,0098978,0099524,1900180,1902430,1990757,2000146 Q13526 9200606 202 KLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 1xqy A 3.2 BS02 PRO A 1 G37 A105 Y106 E213 G34 A102 Y103 E210 G37 A105 Y106 D244 H271 G34 A102 Y103 D241 H268 3.4.11.5 0004177,0006508,0008233 P96084 15994304 294 ECIENYAKVNGIYIYYKLCKAPEEKAKLMTMHGGPGMSHDYLLSLRDMTKEGITVLFYDQFGCGRSEEPDQSKFTIDYGVEEAEALRSKLFGNEKVFLMGSAYGGALALAYAVKYQDHLKGLIVSGGLSSVPLTVKEMNRLIDELPAKYRDAIKKYGSSGSYENPEYQEAVNYFYHQHLLRSEDWPPEVLKSLEYAERRNVYRIMNGPNEFTITGTIKDWDITDKISAIKIPTLITVGEYDEVTPNVARVIHEKIAGSELHVFRDCSHLTMWEDREGYNKLLSDFILKHL 1xrp A 2.3 BS02 PRO A 1 G37 N209 N212 Q213 I216 G34 N206 N209 Q210 I213 G37 S105 Y106 D244 H271 G34 S102 Y103 D241 H268 3.4.11.5 0004177,0006508,0008233 P96084 15994304 301 ECIENYAKVNGIYIYYKLCKAPEEKAKLMTMHGGPGMSHDYLLSLRDMTKEGITVLFYDQFGCGRSEEPDQSKFTIDYGVEEAEALRSKLFGNEKVFLMGSSYGGALALAYAVKYQDHLKGLIVSGGLSSVPLTVKEMNRLIDELPAKYRDAIKKYGSSGSYENPEYQEAVNYFYHQHLLRSEDWPPEVLKSLEYAERRNVYRIMNGPNQFTITGTIKDWDITDKISAIKIPTLITVGEYDEVTPNVARVIHEKIAGSELHVFRDCSHLTMWEDREGYNKLLSDFILKHL 1xrr A 2.4 BS01 PRO A 1 G37 S105 N209 E213 I216 G34 S102 N206 E210 I213 G37 S105 Y106 D244 H271 G34 S102 Y103 D241 H268 3.4.11.5 0004177,0006508,0008233 P96084 15994304 300 ECIENYAKVNGIYIYYKLCKAPEEKAKLMTMHGGPGMSHDYLLSLRDMTKEGITVLFYDQFGCGRSEEPDQSKFTIDYGVEEAEALRSKLFGNEKVFLMGSSYGGALALAYAVKYQDHLKGLIVSGGLSSVPLTVKEMNRLIDELPAKYRDAIKKYGSSGSYENPEYQEAVNYFYHQHLLRSEDWPPEVLKSLEYAERRNVYRIMNGPNEFTITGTIKDWDITDKISAIKIPTLITVGEYDQVTPNVARVIHEKIAGSELHVFRDCSHLTMWEDREGYNKLLSDFILKHL 1xrr A 2.4 BS02 PRO A 2 Y205 N212 Y202 N209 G37 S105 Y106 D244 H271 G34 S102 Y103 D241 H268 3.4.11.5 0004177,0006508,0008233 P96084 15994304 301 ECIENYAKVNGIYIYYKLCKAPEEKAKLMTMHGGPGMSHDYLLSLRDMTKEGITVLFYDQFGCGRSEEPDQSKFTIDYGVEEAEALRSKLFGNEKVFLMGSSYGGALALAYAVKYQDHLKGLIVSGGLSSVPLTVKEMNRLIDELPAKYRDAIKKYGSSGSYENPEYQEAVNYFYHQHLLRSEDWPPEVLKSLEYAERRNVYRIMNGPNEFTITGTIKDWDITDKISAIKIPTLITVGEYDQVTPNVARVIHEKIAGSELHVFRDCSHLTMWEDREGYNKLLSDFILKHL 2amf A 2.2 BS01 PRO A 2 S221 G224 T225 T226 S222 G225 T226 T227 1.5.1.2 0000166,0004735,0005737,0006561,0016491,0055129 Q9A1S9 16233902 4333 AMKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL 2amf A 2.2 BS02 PRO D 1 M11 M109 P110 M12 M110 P111 1.5.1.2 0000166,0004735,0005737,0006561,0016491,0055129 Q9A1S9 16233902 4240 AMKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL 2amf B 2.2 BS01 PRO B 1 I219 S221 I220 S222 1.5.1.2 0000166,0004735,0005737,0006561,0016491,0055129 Q9A1S9 16233902 4242 AMKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL 2amf B 2.2 BS02 PRO B 2 I219 S221 G224 T225 T226 I220 S222 G225 T226 T227 1.5.1.2 0000166,0004735,0005737,0006561,0016491,0055129 Q9A1S9 16233902 4332 AMKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL 2amf B 2.2 BS03 PRO C 1 M11 P110 M12 P111 1.5.1.2 0000166,0004735,0005737,0006561,0016491,0055129 Q9A1S9 16233902 4241 AMKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL 2amf C 2.2 BS01 PRO B 1 M11 P110 M11 P110 1.5.1.2 0000166,0004735,0005737,0006561,0016491,0055129 Q9A1S9 16233902 4242 MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL 2amf C 2.2 BS02 PRO C 2 S221 G224 T225 T226 S221 G224 T225 T226 1.5.1.2 0000166,0004735,0005737,0006561,0016491,0055129 Q9A1S9 16233902 4331 MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL 2amf D 2.2 BS01 PRO A 1 M11 P110 M13 P112 1.5.1.2 0000166,0004735,0005737,0006561,0016491,0055129 Q9A1S9 16233902 4243 NAMKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL 2amf D 2.2 BS02 PRO D 2 I219 S221 G224 T225 T226 I221 S223 G226 T227 T228 1.5.1.2 0000166,0004735,0005737,0006561,0016491,0055129 Q9A1S9 16233902 4330 NAMKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL 2amf E 2.2 BS01 PRO E 1 M11 P110 M14 P113 1.5.1.2 0000166,0004735,0005737,0006561,0016491,0055129 Q9A1S9 16233902 4244 SNAMKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL 2bh3 A 2.4 BS01 PRO A 1 H243 H350 H361 E383 R404 H243 H350 H361 E383 R404 D38 H243 D260 D271 H350 H354 H361 E383 Y387 R404 E406 D38 H243 D260 D271 H350 H354 H361 E383 Y387 R404 E406 3.4.11.9 0004177,0005515,0005737,0005829,0006508,0008235,0008237,0030145,0032991,0042802,0046872,0046914,0051289,0070006 P15034 16229471 501 SEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ 2bn7 A 2.4 BS01 PRO A 1 H243 H350 H361 E383 R404 H243 H350 H361 E383 R404 D38 H243 D260 D271 H350 H354 H361 E383 Y387 R404 E406 D38 H243 D260 D271 H350 H354 H361 E383 Y387 R404 E406 3.4.11.9 0004177,0005515,0005737,0005829,0006508,0008235,0008237,0030145,0032991,0042802,0046872,0046914,0051289,0070006 P15034 16229471 501 SEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ 2cfe A 1.5 BS02 PRO A 1 R53 Q61 F111 R53 Q61 F111 R53 F58 Q61 N100 F111 L120 H124 R53 F58 Q61 N100 F111 L120 H124 5.2.1.8 0000413,0003755,0006457 O93970 16483252 1162 MSNVFFDITKNGAPLGTIKFKLFDDVVPKTAANFRALCTGEKGFGYAGSHFHRVIPDFMLQGGDFTAGNGTGGKSIYGAKFADENFQLKHNKPGLLSMANAGPNTNGSQFFITTVVTSWLDGKHVVFGEVIDGMNVVKAIEAEGSGSGKPRSRIEIAKCGVC 2cyh A 1.64 BS02 PRO A 1 R55 F113 R54 F112 R55 F60 Q63 N102 F113 L122 H126 R54 F59 Q62 N101 F112 L121 H125 5.2.1.8 0000413,0001933,0001934,0003723,0003755,0005178,0005515,0005576,0005615,0005634,0005737,0005829,0005925,0006457,0006469,0006915,0016018,0016020,0019076,0030168,0030182,0030593,0030595,0031982,0032148,0032873,0032991,0034389,0034599,0034774,0035307,0042118,0043410,0045069,0045070,0046790,0050714,0051082,0051092,0060352,0061944,0070062,0070527,1902176,1903901,1904399,1904813,2001233 P62937 8652512 202 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 2eiw A 1.9 BS01 PRO A 1 E137 F185 S323 G477 A478 F485 E137 F185 S323 G477 A478 F485 N184 K207 E288 C322 E417 T497 N184 K207 E288 C322 E417 T497 1.2.1.88 0000166,0003842,0009898,0010133,0016491,0016620 Q5SI02 5517 MTVEPFRNEPIETFQTEEARRAMREALRRVREEFGRHYPLYIGGEWVDTKERMVSLNPSAPSEVVGTTAKAGKAEAEAALEAAWKAFKTWKDWPQEDRSRLLLKAAALMRRRKRELEATLVYEVGKNWVEASADVAEAIDFIEYYARAALRYRYPAVEVVPYPGEDNESFYVPLGAGVVIAPWNFPVAIFTGMIVGPVAVGNTVIAKPAEDAVVVGAKVFEIFHEAGFPPGVVNFLPGVGEEVGAYLVEHPRIRFINFTGSLEVGLKIYEAAGRLAPGQTWFKRAYVETGGKNAIIVDETADFDLAAEGVVVSAYGFQGQKCSAASRLILTQGAYEPVLERVLKRAERLSVGPAEENPDLGPVVSAEQERKVLSYIEIGKNEGQLVLGGKRLEGEGYFIAPTVFTEVPPKARIAQEEIFGPVLSVIRVKDFAEALEVANDTPYGLTGGVYSRKREHLEWARREFHVGNLYFNRKITGALVGVQPFGGFKLSGTNAKTGALDYLRLFLEMKAVAERF 2eiw B 1.9 BS01 PRO B 1 E137 F185 S323 G477 A478 F485 E137 F185 S323 G477 A478 F485 N184 K207 E288 C322 E417 T497 N184 K207 E288 C322 E417 T497 1.2.1.88 0000166,0003842,0009898,0010133,0016491,0016620 Q5SI02 5541 MTVEPFRNEPIETFQTEEARRAMREALRRVREEFGRHYPLYIGGEWVDTKERMVSLNPSAPSEVVGTTAKAGKAEAEAALEAAWKAFKTWKDWPQEDRSRLLLKAAALMRRRKRELEATLVYEVGKNWVEASADVAEAIDFIEYYARAALRYRYPAVEVVPYPGEDNESFYVPLGAGVVIAPWNFPVAIFTGMIVGPVAVGNTVIAKPAEDAVVVGAKVFEIFHEAGFPPGVVNFLPGVGEEVGAYLVEHPRIRFINFTGSLEVGLKIYEAAGRLAPGQTWFKRAYVETGGKNAIIVDETADFDLAAEGVVVSAYGFQGQKCSAASRLILTQGAYEPVLERVLKRAERLSVGPAEENPDLGPVVSAEQERKVLSYIEIGKNEGQLVLGGKRLEGEGYFIAPTVFTEVPPKARIAQEEIFGPVLSVIRVKDFAEALEVANDTPYGLTGGVYSRKREHLEWARREFHVGNLYFNRKITGALVGVQPFGGFKLSGTNAKTGALDYLRLFLEMKAVAERF 2fzn A 2.0 BS02 PRO A 1 K329 L513 Y540 R555 R556 K168 L352 Y379 R394 R395 1.2.1.88,1.5.5.2 0003842,0004657,0006562 P09546 2002 QSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGGVALMCLAEALLRIPDKATRDALIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEESDRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRD 2igv A 1.67 BS02 PRO A 1 R62 Q70 F120 H133 R62 Q70 F120 H133 R62 F67 Q70 N109 F120 L129 H133 R62 F67 Q70 N109 F120 L129 H133 5.2.1.8 0000413,0003755,0005515,0005634,0005737,0005739,0006457,0016018 -logKd/Ki=2.23, Kd=5.9mM P52011 17654646 202 MSRSKVFFDITIGGKASGRIVMELYDDVVPKTAGNFRALCTGENGIGKSGKPLHFKGSKFHRIIPNFMIQGGDFTRGNGTGGESIYGEKFPDENFKEKHTGPGVLSMANAGPNTNGSQFFLCTVKTEWLDGKHVVFGRVVEGLDVVKAVESNGSQSGKPVKDCMIADCGQLK 2igw A 1.78 BS02 PRO A 1 R62 Q70 F120 R62 Q70 F120 R62 F67 Q70 N109 F120 L129 H133 R62 F67 Q70 N109 F120 L129 H133 5.2.1.8 0000413,0003755,0005515,0005634,0005737,0005739,0006457,0016018 -logKd/Ki=1.31, Kd=49mM P52011 17654646 202 MSRSKVFFDITIGGKASGRIVMELYDDVVPKTAGNFRALCTGENGIGKSGKPLHFKGSKFHRIIPNFMIQGGDFTRGNGTGGESIYGEKFPDENFKEKHTGPGVLSMANAGPNTNGSQFFLCTVKTEWLDGKHVVFGRVVEGLDVVKAVESNGSQSGKPVKDCMIADCGQLK 2j40 A 2.1 BS01 PRO A 1 E137 F185 C322 S323 G477 A478 F485 E137 F185 C322 S323 G477 A478 F485 N184 K207 E288 C322 E417 T497 N184 K207 E288 C322 E417 T497 1.2.1.88 0000166,0003842,0009898,0010133,0016491,0016620 Q5SI02 1517 MTVEPFRNEPIETFQTEEARRAMREALRRVREEFGRHYPLYIGGEWVDTKERMVSLNPSAPSEVVGTTAKAGKAEAEAALEAAWKAFKTWKDWPQEDRSRLLLKAAALMRRRKRELEATLVYEVGKNWVEASADVAEAIDFIEYYARAALRYRYPAVEVVPYPGEDNESFYVPLGAGVVIAPWNFPVAIFTGMIVGPVAVGNTVIAKPAEDAVVVGAKVFEIFHEAGFPPGVVNFLPGVGEEVGAYLVEHPRIRFINFTGSLEVGLKIYEAAGRLAPGQTWFKRAYVETGGKDAIIVDETADFDLAAEGVVVSAYGFQGQKCSAASRLILTQGAYEPVLERVLKRAERLSVGPAEENPDLGPVVSAEQERKVLSYIEIGKNEGQLVLGGKRLEGEGYFIAPTVFTEVPPKARIAQEEIFGPVLSVIRVKDFAEALEVANDTPYGLTGGVYSRKREHLEWARREFHVGNLYFNRKITGALVGVQPFGGFKLSGTNAKTGALDYLRLFLEMKAVAERF 2j40 B 2.1 BS01 PRO B 1 E137 F185 C322 S323 G477 A478 F485 E137 F185 C322 S323 G477 A478 F485 N184 K207 E288 C322 E417 T497 N184 K207 E288 C322 E417 T497 1.2.1.88 0000166,0003842,0009898,0010133,0016491,0016620 Q5SI02 1518 MTVEPFRNEPIETFQTEEARRAMREALRRVREEFGRHYPLYIGGEWVDTKERMVSLNPSAPSEVVGTTAKAGKAEAEAALEAAWKAFKTWKDWPQEDRSRLLLKAAALMRRRKRELEATLVYEVGKNWVEASADVAEAIDFIEYYARAALRYRYPAVEVVPYPGEDNESFYVPLGAGVVIAPWNFPVAIFTGMIVGPVAVGNTVIAKPAEDAVVVGAKVFEIFHEAGFPPGVVNFLPGVGEEVGAYLVEHPRIRFINFTGSLEVGLKIYEAAGRLAPGQTWFKRAYVETGGKDAIIVDETADFDLAAEGVVVSAYGFQGQKCSAASRLILTQGAYEPVLERVLKRAERLSVGPAEENPDLGPVVSAEQERKVLSYIEIGKNEGQLVLGGKRLEGEGYFIAPTVFTEVPPKARIAQEEIFGPVLSVIRVKDFAEALEVANDTPYGLTGGVYSRKREHLEWARREFHVGNLYFNRKITGALVGVQPFGGFKLSGTNAKTGALDYLRLFLEMKAVAERF 2qer A 2.17 BS02 PRO A 1 K60 Y135 K44 Y117 K60 F65 Q68 S107 F122 L131 Y135 K44 F49 Q52 S91 F104 L113 Y117 5.2.1.8 0000413,0003755,0071013 A3FQ68 188 QGVRIITNYGDLKFELFCSQCPKACKNFLALSASGYYKNTIFHKNIKGFIIQGGDPTGTGKGGESIYGRYFDDEIYPELKYDRRGILSMASASKKPNTNGSQFFITYSSLPQLNGEYVIFGKLIDGFETLNTLENCPSDKSHKPIDEIIIKDIVIHSN 2vvm A 1.85 BS02 PRO A 1 W94 L213 F382 W430 W88 L207 F376 W424 H96 H90 1.4.3.4 0005777,0016491,0097621 P46882 18951902 601 MTSRDGYQWTPETGLTQGVPSLGVISPPTNIGPWDVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGGRSWSSNIDGYPYEMGGTWVHWHQSHVWREITRYKMHNALSPSFNFSRGVNHFQLRTNPTTSTYMTHEAEDELLRSALHKFTNVDGTNGRTVLPFPHDMFYVPEFRKYDEMSYSERIDQIRDELSLNERSSLEAFILLCSGGTLENSSFGEFLHWWAMSGYTYQGCMDCLMSYKFKDGQSAFARRFWEEAAGTGRLGYVFGCPVRSVVNERDAARVTARDGREFVAKRVVCTIPLNVLSTIQFSPALSTERISAMQAGHVSMCTKVHAEVDNKDMRSWTGIAYPFNKLCYAIGDGTTPAGNTHLVCFGNSANHIQPDEDVRETLKAVGQLAPGTFGVKRLVFHNWVKDEFAKGAWFFSRPGMVSECLQGLREKHGGVVFANSDWALGWRSFIDGAIEEGTRAARVVLEELGT 2vvm B 1.85 BS02 PRO B 1 L213 K340 F382 W430 L205 K332 F374 W422 H96 H88 1.4.3.4 0005777,0016491,0097621 P46882 18951902 601 MTSRDGYQWTPETGLTQGVPSLGVISPPTNIWDVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGGRSWSSNIDGYPYEMGGTWVHWHQSHVWREITRYKMHNALSPSFNFSRGVNHFQLRTNPTTSTYMTHEAEDELLRSALHKFTNVDGTNGRTVLPFPHDMFYVPEFRKYDEMSYSERIDQIRDELSLNERSSLEAFILLCSGGTLENSSFGEFLHWWAMSGYTYQGCMDCLMSYKFKDGQSAFARRFWEEAAGTGRLGYVFGCPVRSVVNERDAARVTARDGREFVAKRVVCTIPLNVLSTIQFSPALSTERISAMQAGHVSMCTKVHAEVDNKDMRSWTGIAYPFNKLCYAIGDGTTPAGNTHLVCFGNSANHIQPDEDVRETLKAVGQLAPGTFGVKRLVFHNWVKDEFAKGAWFFSRPGMVSECLQGLREKHGGVVFANSDWALGWRSFIDGAIEEGTRAARVVLEELG 2xu0 A 2.06 BS01 PRO A 1 A125 N126 G127 M400 A85 N86 G87 M360 ? 0016020,0046789 B7T1P0 21402930 1493 SPTLSESHKSARNVLENIGIKIYNQEIKKKNPYEQQLKGTLDGNSCNLDHLFGRKPCYGREQNRFDENAEAYCNSDKIRGNENNANGAACAPPRRRHICDQNLEFLDNKNTNTAHDLLGNVLVTAKYEGNYIVNDHPDKNSNGNKAGICTSLARSFADIGDIVRGRDMFLPNKDDKVQKGLQVVFKKIYKSLTPEARKHYAHGDGSGNYAKLREDWWTINREQIWKALTCSAPYYADYFRKGSDGTLHFSSHGKCGHNEGAPPTYLDYVPQFLRWFEEWSEEFCRIKKIKIDKVKKECRDEQNKKYCSGDGHDCTQTNLAHNQIFVDLDCPRCQDQCIKYNEWIVKKLEEFYKQNLKYSMEIQKWKKTKNNYYDKEFYENLDKKSYSTIDKFLNLLNNGKHCHDNKDEKNKIDFNKPIKTFSISEYCKTCPLYGVTCTNRGICIHNS 3axb A 1.92 BS01 PRO A 1 M48 R52 Y88 M382 M48 R52 Y88 M382 ? 0000166,0005737,0016020,0016491 Q9YCJ0 22511758 2001 MPRFDYVVVGAGVVGLAAAYYLKVWSGGSVLVVDAGHAPGSGDSGRSMAAFRTFFSSTMNRLVAGSTVRLFEDAQRGGEDLGLVKSGYLFVYDRERWREVEEPLREAGEEGRDYLIIPPEELERRLGMNTRVSDGEEAEVLGVGDVEGAVLIRSAGFLDAEKVVDYYYRRASGAGVEFIFGRRVVGVELKPRVELGIEGEPLPWQEARASAAVLSDGTRVEVGEKLVVAAGVWSNRLLNPLGIDTFSRPKKRMVFRVSASTEGLRRIMREGDLAGAGAPPLIILPKRVLVRPAPREGSFWVQLSDNLGRPFALEEDPQPEEHYYSLAILPILSLYLPQFQDAYPSGGWAGHYDISFDANPVVFEPWESGIVVAAGTSGSGIMKSDSIGRVAAAVALGMESVELYGGVEMPVKWMGLEGRRYEQERLVL 3c03 A 1.9 BS01 PRO A 1 Y316 K317 H320 Y70 K71 H74 ? 0009306,0016020 Q9AJ26 18451864 4 GSLANNIKKSTVIVKNATHIAICLYYKLGETPLPLVIETGKDAKALQIIKLAELYDIPVIEDIPLARSLYKNIHKGQYITEDFFEPVAQLIRIAIDL 3cmm A 2.7 BS01 PRO A 1 D316 N320 D305 N309 R21 R481 D544 C600 T601 R603 N781 D782 R10 R470 D533 C589 T590 R592 N767 D768 6.2.1.45 0004839,0005515,0005524,0005634,0005737,0006511,0006974,0008641,0016567,0016874,0036211,0043412 P22515 18662542 5119 GEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 3cmm C 2.7 BS01 PRO C 1 D316 N320 K349 D306 N310 K339 R21 R481 D544 C600 T601 R603 N781 D782 R11 R471 D534 C590 T591 R593 N771 D772 6.2.1.45 0004839,0005515,0005524,0005634,0005737,0006511,0006974,0008641,0016567,0016874,0036211,0043412 P22515 18662542 5129 AGEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKQSGDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPGSDEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 3cyh A 1.9 BS02 PRO A 1 R55 Q63 F113 R54 Q62 F112 R55 F60 Q63 N102 F113 L122 H126 R54 F59 Q62 N101 F112 L121 H125 5.2.1.8 0000413,0001933,0001934,0003723,0003755,0005178,0005515,0005576,0005615,0005634,0005737,0005829,0005925,0006457,0006469,0006915,0016018,0016020,0019076,0030168,0030182,0030593,0030595,0031982,0032148,0032873,0032991,0034389,0034599,0034774,0035307,0042118,0043410,0045069,0045070,0046790,0050714,0051082,0051092,0060352,0061944,0070062,0070527,1902176,1903901,1904399,1904813,2001233 P62937 8652512 202 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 3e2s A 2.0 BS01 PRO A 1 K329 L513 Y552 R555 R556 K187 L371 Y410 R413 R414 1.2.1.88,1.5.5.2 0003842,0004657,0006562 P09546 19140736 1 QSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEESDRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRISAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRD 3fwe A 2.3 BS01 PRO A 1 T28 Q32 K52 T23 Q27 K47 ? 0003677,0003680,0003700,0005515,0005829,0006351,0006355,0008301,0030552,0032993,0042802,0043565,0045013,0045892,0045893 P0ACJ8 19805344 210 QTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLLVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYG 3fwe A 2.3 BS02 PRO A 2 V108 N109 V103 N104 ? 0003677,0003680,0003700,0005515,0005829,0006351,0006355,0008301,0030552,0032993,0042802,0043565,0045013,0045892,0045893 P0ACJ8 19805344 211 QTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLLVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYG 3ijl A 1.5 BS01 PRO A 1 C326 D348 D350 L354 C280 D302 D304 L308 F61 T174 L197 K198 K200 D224 N226 E251 D276 E277 K298 G325 C326 M327 D345 A347 D348 L349 F15 T128 L151 K152 K154 D178 N180 E205 D230 E231 K252 G279 C280 M281 D299 A301 D302 L303 5.1.1.20 0016855 Q8A861 22392983 384 KMTFFPYELKLRHVFTVATYSRTTTPDVQVEIEYEGVTGYGEASMPPYLGETVESVMNFLKKVNLEQFSDPFQLEDILSYVDSLSPKDTAAKAAVDIALHDLVGKLLGAPWYKIWGLNKEKTPSTTFTIGIDTPDVVRAKTKECAGLFNILKVKLGRDNDKEMIETIRSVTDLPIAVDANQGWKDRQYALDMIHWLKEKGIVMIEQPMPKEQLDDIAWVTQQSPLPVFADESLQRLGDVAALKGAFTGINIKLMKCTGMREAWKMVTLAHALGMRVMVGCMTETSCAISAASQFSPAVDFADLDGNLLISNDRFKGVEVVNGKITLNDLPGIGVMK 3ijl B 1.5 BS01 PRO B 1 F61 C326 D348 D350 L354 F15 C280 D302 D304 L308 F61 T174 L197 K198 K200 D224 N226 E251 D276 E277 K298 G325 C326 M327 D345 A347 D348 L349 F15 T128 L151 K152 K154 D178 N180 E205 D230 E231 K252 G279 C280 M281 D299 A301 D302 L303 5.1.1.20 0016855 Q8A861 22392983 384 KMTFFPYELKLRHVFTVATYSRTTTPDVQVEIEYEGVTGYGEASMPPYLGETVESVMNFLKKVNLEQFSDPFQLEDILSYVDSLSPKDTAAKAAVDIALHDLVGKLLGAPWYKIWGLNKEKTPSTTFTIGIDTPDVVRAKTKECAGLFNILKVKLGRDNDKEMIETIRSVTDLPIAVDANQGWKDRQYALDMIHWLKEKGIVMIEQPMPKEQLDDIAWVTQQSPLPVFADESLQRLGDVAALKGAFTGINIKLMKCTGMREAWKMVTLAHALGMRVMVGCMTETSCAISAASQFSPAVDFADLDGNLLISNDRFKGVEVVNGKITLNDLPGIGVMK 3ip6 A 1.4 BS01 PRO A 1 F77 N78 S79 A100 A101 T102 Y150 D226 Y275 F77 N78 S79 A100 A101 T102 Y150 D226 Y275 ? 0006865,0046872 Kd=0.25uM -logKd/Ki=6.60, Kd=0.25uM Q7CX36 20630861 500 MDVVIAVGAPLTGPNAAFGAQIQKGAEQAAKDINAAGGINGEQIKIVLGDDVSDPKQGISVANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEITPAATNPVFTERGLWNTFRTCGRDDQQGGIAGKYLADHFKDAKVAIIHDKTPYGQGLADETKKAANAAGVTEVMYEGVNVGDKDFSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGLKAKLVSGDGIVSNELASIAGDAVEGTLNTFGPDPTLRPENKELVEKFKAAGFNPEAYTLYSYAAMQAIAGAAKAAGSVEPEKVAEALKKGSFPTALGEISFDEKGDPKLPGYVMYEWKKGPDGKFTYIQQ 3lku A 2.8 BS01 PRO A 1 S48 Y49 E50 H51 S35 Y36 E37 H38 ? 0003674,0005515,0005737,0005829,0006620,0016192,0045048,0072380 Q12125 20554915 1 AKTLQRFENKIKAGDYYEAHQTLRTIANRYVRSKSYEHAIELISQGALSFLKAKQGGSGTDLIFYLLEVYDLAEVKVDDISVARLVRLIAELDPSEPNLKDVITGMNNWSIKFSEYKFGDPYLHNTIGSKLLEGDFVYEAERYFMLGTHDSMIKYVDLLWDWLCQVDDIEDSTVAEFFSRLVFNYLFISNISFAHESKDIFLERFIEKFHPKYEKIDKNGYEIVFFEDYSDLNFLQLLLITCQTKDKSYFLNLKNHYLDFSQAYKSELEFLGQEYFNIVAPKQTNF 3lku E 2.8 BS01 PRO E 1 S48 E50 H51 S40 E42 H43 ? 0003674,0005515,0005737,0005829,0006620,0016192,0045048,0072380 Q12125 20554915 1 MGAKLAKTLQRFENKIKAGDYYEAHQTLRTIANRYVRSKSYEHAIELISQGALSFLKAKQGGSGTDLIFYLLEVYDLAEVKVDDISVARLVRLIAELDPSEPNLKDVITGMNNWSIKFSEYKFGDPYLHNTIGSKLLEGDFVYEAERYFMLGTHDSMIKYVDLLWDWLCQVDDIEDSTVAEFFSRLVFNYLFISNISFAHESKDIFLERFIEKFHPKYEKIDKNGYEIVFFEDYSDLNFLQLLLITCQTKDKSYFLNLKNHYLDFSQAYKSELEFLGQEYFNIVAPKQTNF 3n25 A 2.41 BS01 PRO A 1 N43 N69 H463 I468 F469 N32 N58 H452 I457 F458 R72 R119 K269 T327 R61 R108 K258 T316 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003729,0003824,0004713,0004743,0005515,0005524,0005634,0005737,0005791,0006096,0006417,0016301,0016310,0030955,0032869,0046872,1903672,2000767 P11974 20629175 1200 IQTQQLHAAMADTFLEHKCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARASSQSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 3n25 B 2.41 BS01 PRO B 1 N43 N69 H463 I468 F469 N33 N59 H441 I446 F447 R72 R119 K269 T327 R62 R109 K247 T305 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003729,0003824,0004713,0004743,0005515,0005524,0005634,0005737,0005791,0006096,0006417,0016301,0016310,0030955,0032869,0046872,1903672,2000767 P11974 20629175 1600 FIQTQQLHAAMADTFLEHKCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARASSQSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 3n25 C 2.41 BS01 PRO C 1 N43 G45 N69 H463 I468 F469 N32 G34 N58 H445 I450 F451 R72 R119 K269 T327 R61 R108 K251 T309 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003729,0003824,0004713,0004743,0005515,0005524,0005634,0005737,0005791,0006096,0006417,0016301,0016310,0030955,0032869,0046872,1903672,2000767 P11974 20629175 1600 IQTQQLHAAMADTFLEHKCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARASSQSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 3n25 D 2.41 BS01 PRO D 1 N43 N69 H463 I468 F469 N34 N60 H454 I459 F460 R72 R119 K269 T327 R63 R110 K260 T318 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003729,0003824,0004713,0004743,0005515,0005524,0005634,0005737,0005791,0006096,0006417,0016301,0016310,0030955,0032869,0046872,1903672,2000767 P11974 20629175 1600 AFIQTQQLHAAMADTFLEHKCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARASSQSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 3n25 E 2.41 BS01 PRO E 1 N43 N69 H463 I468 F469 N34 N60 H454 I459 F460 R72 R119 K269 T327 R63 R110 K260 T318 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003729,0003824,0004713,0004743,0005515,0005524,0005634,0005737,0005791,0006096,0006417,0016301,0016310,0030955,0032869,0046872,1903672,2000767 P11974 20629175 1600 AFIQTQQLHAAMADTFLEHKCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARASSQSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 3n25 F 2.41 BS01 PRO F 1 N43 N69 H463 I468 F469 N33 N59 H448 I453 F454 R72 R119 K269 T327 R62 R109 K254 T312 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003729,0003824,0004713,0004743,0005515,0005524,0005634,0005737,0005791,0006096,0006417,0016301,0016310,0030955,0032869,0046872,1903672,2000767 P11974 20629175 1600 FIQTQQLHAAMADTFLEHKCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARASSQSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 3n25 G 2.41 BS01 PRO G 1 N43 N69 H463 Y465 I468 F469 N33 N59 H443 Y445 I448 F449 R72 R119 K269 T327 R62 R109 K249 T307 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003729,0003824,0004713,0004743,0005515,0005524,0005634,0005737,0005791,0006096,0006417,0016301,0016310,0030955,0032869,0046872,1903672,2000767 P11974 20629175 1600 FIQTQQLHAAMADTFLEHKCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARASSQSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 3n25 H 2.41 BS01 PRO H 1 N43 N69 H463 I468 F469 N33 N59 H452 I457 F458 R72 R119 K269 T327 R62 R109 K258 T316 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003729,0003824,0004713,0004743,0005515,0005524,0005634,0005737,0005791,0006096,0006417,0016301,0016310,0030955,0032869,0046872,1903672,2000767 P11974 20629175 1600 FIQTQQLHAAMADTFLEHKCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARASSQSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 3n8h A 2.001 BS01 PRO A 1 M29 Q60 R121 H124 D150 Q153 R187 M30 Q61 R122 H125 D151 Q154 R188 M29 H33 H36 Q76 D77 I80 K149 S185 S186 R187 M30 H34 H37 Q77 D78 I81 K150 S186 S187 R188 6.3.2.1 0003824,0004592,0005524,0005737,0005829,0009058,0015940,0016874 Q5NF57 271 AMIIADNIKQFHSIRNSLIKQQKIGFVPTMGALHNGHISLIKKAKSENDVVIVSIFVNPTQFNNPNDYQTYPNQLQQDIQILASLDVDVLFNPSEKDIYPDGNLLRIEPKLEIANILEGKSRPGHFSGMLTVVLKLLQITKPNNLYLGEKDYQQVMLIKQLVKDFFINTKIIVCPTQRQPSGLPLSSRNKNLTSTDIEIANKIYEILRQDDFSNLEELTNKINSTGAKLQYIQKLNNRIFLAFYIGKVRLIDNFLKETGPSC 3n8h B 2.001 BS01 PRO B 1 M29 Q60 R121 H124 D150 Q153 M30 Q61 R122 H125 D151 Q154 M29 H33 H36 Q76 D77 I80 K149 S185 S186 R187 M30 H34 H37 Q77 D78 I81 K150 S186 S187 R188 6.3.2.1 0003824,0004592,0005524,0005737,0005829,0009058,0015940,0016874 Q5NF57 271 AMIIADNIKQFHSIRNSLIKQQKIGFVPTMGALHNGHISLIKKAKSENDVVIVSIFVNPTQFNNPNDYQTYPNQLQQDIQILASLDVDVLFNPSEKDIYPDGNLLRIEPKLEIANILEGKSRPGHFSGMLTVVLKLLQITKPNNLYLGEKDYQQVMLIKQLVKDFFINTKIIVCPTQRQPSGLPLSSRNKNLTSTDIEIANKIYEILRQDDFSNLEELTNKINSTGAKLQYIQKLNNRIFLAFYIGKVRLIDNFLKETGPSC 3qtt A 2.599 BS02 PRO A 1 M32 Q63 M131 V135 Q156 M30 Q61 M129 V133 Q154 M32 H36 H39 Q79 D80 I83 K152 S188 S189 R190 M30 H34 H37 Q77 D78 I81 K150 S186 S187 R188 6.3.2.1 0003824,0004592,0005524,0005737,0005829,0009058,0015940,0016874 Q5NF57 274 AMIIADNIKQFHSIRNSLIKQQKIGFVPTMGALHNGHISLIKKAKSENDVVIVSIFVNPTQFNNPNDYQTYPNQLQQDIQILASLDVDVLFNPSEKDIYPDGNLLRIEPKLEIANILEGKSRPGHFSGMLTVVLKLLQITKPNNLYLGEKDYQQVMLIKQLVKDFFINTKIIVCPTQRQPSGLPLSSRNKNLTSTDIEIANKIYEILRQDDFSNLEELTNKINSTGAKLQYIQKLNNRIFLAFYIGKVRLIDNFLKETGPS 3qtt B 2.599 BS01 PRO B 1 Q63 Q156 Q61 Q154 M32 H36 H39 Q79 D80 I83 K152 S188 S189 R190 M30 H34 H37 Q77 D78 I81 K150 S186 S187 R188 6.3.2.1 0003824,0004592,0005524,0005737,0005829,0009058,0015940,0016874 Q5NF57 272 AMIIADNIKQFHSIRNSLIKQQKIGFVPTMGALHNGHISLIKKAKSENDVVIVSIFVNPTQFNNPNDYQTYPNQLQQDIQILASLDVDVLFNPSEKDIYPDGNLLRIEPKLEIANILEGKSRPGHFSGMLTVVLKLLQITKPNNLYLGEKDYQQVMLIKQLVKDFFINTKIIVCPTQRQPSGLPLSSRNKNLTSTDIEIANKIYEILRQDDFSNLEELTNKINSTGAKLQYIQKLNNRIFLAFYIGKVRLIDNFLKEPS 3vca A 1.59 BS03 PRO A 1 T61 E68 L92 K95 R97 T56 E63 L87 K90 R92 H109 E201 H204 H209 N357 H104 E196 H199 H204 N348 ? 0005506,0044237,0046872,0051213,0051537 Q92ZP9 22224443 504 TSIHQRLDRRLSGFSLEQPFYTSPEVYALDLQHIFYKQWLYAVPVCQLAKAGSYTTLRVGAYEVVIVRSRDGEVRAFHNSCRHRGSLICKARQGQVAKLVCPYHQWTYELDGKLIWANDMGPDFDASKYGLKPVNLRNLDGLIYICLSDTPPDFQTFAQLARPYLEVHDLKDAKVAFTSTIIEKGNWKLVWENNRECYHCSSNHPALCRSFPLDPEVAGVGVSKKLQAHFDRCEAAGTPAQFVLAGDGQYRLARMPLQEKALSYTMDGKAAVSRHLGRVAPPDAGTLLMFHYPSTWNHFLPDHSLTFRVMPISPTETEVTTTWLVHKDAVEGVDYDLKRLTEVWIATNDEDREIVETNQQGILSPAYVPGPYSPGQESGVMQFVDWYAASLERALAP 3vcp A 2.2 BS03 PRO A 1 N199 E201 H209 A223 W353 N194 E196 H204 A218 W344 H109 E201 H204 H209 N357 H104 E196 H199 H204 N348 ? 0005506,0044237,0046872,0051213,0051537 Q92ZP9 22224443 502 TSIHQRLDRRLSGFSLEQPFYTSPEVYALDLQHIFYKQWLYAVPVCQLAKAGSYTTLRVGAYEVVIVRSRDGEVRAFHNSCRHRGSLICKARQGQVAKLVCPYHQWTYELDGKLIWANDMGPDFDASKYGLKPVNLRNLDGLIYICLSDTPPDFQTFAQLARPYLEVHDLKDAKVAFTSTIIEKGNWKLVWENNRECYHCSSNHPALCRSFPLDPEVAGVGVSKKLQAHFDRCEAAGTPAQFVLAGDGQYRLARMPLQEKALSYTMDGKAAVSRHLGRVAPPDAGTLLMFHYPSTWNHFLPDHSLTFRVMPISPTETEVTTTWLVHKDAVEGVDYDLKRLTEVWIATNDEDREIVETNQQGILSPAYVPGPYSPGQESGVMQFVDWYAASLERALAP 3zqs A 2.0 BS01 PRO A 1 S222 T224 S114 T116 2.3.2.27 0004842,0036297,0043240 Q9NW38 21775430 1302 QFYSSLIEEIGTLGWDKLVYADTCFSTIKLKAEDASGREHLITLKLKAKYPAESPDYFVDFPVPFCASWTPQSSLISIYSQFLAAIESLKAFWDVMDEIDEKTWVLEPEKPPRSATARRIALGNNVSINIEVDPRHPTMLPECFFLGADHVVKPLGIKLSRNIHLWDPENSVLQNLKDVLEIDFPA 4cyh A 2.1 BS02 PRO A 1 R55 F113 R54 F112 R55 F60 Q63 N102 F113 L122 H126 R54 F59 Q62 N101 F112 L121 H125 5.2.1.8 0000413,0001933,0001934,0003723,0003755,0005178,0005515,0005576,0005615,0005634,0005737,0005829,0005925,0006457,0006469,0006915,0016018,0016020,0019076,0030168,0030182,0030593,0030595,0031982,0032148,0032873,0032991,0034389,0034599,0034774,0035307,0042118,0043410,0045069,0045070,0046790,0050714,0051082,0051092,0060352,0061944,0070062,0070527,1902176,1903901,1904399,1904813,2001233 P62937 8652512 202 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4e3u A 1.5 BS01 PRO A 1 N19 G22 S24 N19 G22 S24 E35 N46 D48 S50 D52 N59 E35 N46 D48 S50 D52 N59 3.2.1.17 0003796,0005515,0005576,0005615,0005737,0005783,0016231,0016798,0016998,0031640,0042742,0042802,0050829,0050830,0051672 P00698 22868767 201 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 4e3v A 1.503 BS01 PRO A 1 Y280 S281 Y278 S279 H54 D57 M88 E181 K183 E217 H220 D245 D255 D257 D287 H52 D55 M86 E179 K181 E215 H218 D243 D253 D255 D285 5.3.1.5 0000287,0005737,0005975,0009045,0016853,0042732,0042802,0046872 P24300 22868767 401 YQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVESVRRLAELGAHGVTFHDDDLIPFGSSDSEREEHVKRFRQALDDTGMKVPMATTNLFTHPVFKDGGFTANDRDVRRYALRKTIRNIDLAVELGAETYVAWGGREGAESGGAKDVRDALDRMKEAFDLLGEYVTSQGYDIRFAIEPKPNEPRGDILLPTVGHALAFIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQNGIKYDQDLRFGAGDLRAAFWLVDLLESAGYSGPRHFDFKPPRTEDFDGVWASAAGCMRNYLILKERAAAFRADPEVQEALRASRLDELARPTAADGLQALLDDRSAFEEFDVDAAAARGMAFERLDQLAMDHLLGAR 4e3w A 1.75 BS03 PRO A 1 F23 Y135 F18 Y130 22868767 403 SKLIFVSMITRNGDRAPFANIENANYSWGTELSELTPIGMNQEYNLGLQLRKRYIDKFGLLPEHYVDQSIYVLSSHTNRTVVSAQSLLMGLYPAGTGPLIGDGDPAIKDRFQPIPIMTLSADSRLIQFPYEQYLAVLKKYVYNSPEWQNKTKEAAPNFAKWQQILGNRISGLNDVITVGDVLIVAQAHGKPLPKGLSQEDADQIIALTDWGLAQQFKSQKVSYIMGGKLTNRMIEDLNNAVNGKSKYKMTYYSGHALTLLEVMGTLGVPLDTAPGYASNLEMELYKDGDIYTVKLRYNGKYVKLPIMDKNNSCSLDALNKYMQSINEKF 4e3w B 1.75 BS03 PRO B 1 F23 Y135 F18 Y130 22868767 403 SKLIFVSMITRNGDRAPFANIENANYSWGTELSELTPIGMNQEYNLGLQLRKRYIDKFGLLPEHYVDQSIYVLSSHTNRTVVSAQSLLMGLYPAGTGPLIGDGDPAIKDRFQPIPIMTLSADSRLIQFPYEQYLAVLKKYVYNSPEWQNKTKEAAPNFAKWQQILGNRISGLNDVITVGDVLIVAQAHGKPLPKGLSQEDADQIIALTDWGLAQQFKSQKVSYIMGGKLTNRMIEDLNNAVNGKSKYKMTYYSGHALTLLEVMGTLGVPLDTAPGYASNLEMELYKDGDIYTVKLRYNGKYVKLPIMDKNNSCSLDALNKYMQSINEKF 4e3x A 1.24 BS01 PRO A 1 L302 D303 F305 T307 F308 L283 D284 F286 T288 F289 N211 K233 E314 C348 E447 P532 N192 K214 E295 C329 E428 P513 1.2.1.88 0003842,0004029,0005739,0005759,0005829,0006560,0010133,0016491,0016620,0042802 Q8CHT0 22868767 601 HMLRWKHTSSLKVANEPILAFSQGSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYM 4e3x A 1.24 BS02 PRO A 2 F210 D393 F191 D374 N211 K233 E314 C348 E447 P532 N192 K214 E295 C329 E428 P513 1.2.1.88 0003842,0004029,0005739,0005759,0005829,0006560,0010133,0016491,0016620,0042802 Q8CHT0 22868767 602 HMLRWKHTSSLKVANEPILAFSQGSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYM 4e3x A 1.24 BS03 PRO A 3 Q184 P185 I186 Q165 P166 I167 N211 K233 E314 C348 E447 P532 N192 K214 E295 C329 E428 P513 1.2.1.88 0003842,0004029,0005739,0005759,0005829,0006560,0010133,0016491,0016620,0042802 Q8CHT0 22868767 603 HMLRWKHTSSLKVANEPILAFSQGSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYM 4e3x A 1.24 BS04 PRO A 4 C348 S349 T511 G512 S513 F520 C329 S330 T492 G493 S494 F501 N211 K233 E314 C348 E447 P532 N192 K214 E295 C329 E428 P513 1.2.1.88 0003842,0004029,0005739,0005759,0005829,0006560,0010133,0016491,0016620,0042802 Q8CHT0 22868767 604 HMLRWKHTSSLKVANEPILAFSQGSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYM 4e3x A 1.24 BS05 PRO B 1 K292 A525 K273 A506 N211 K233 E314 C348 E447 P532 N192 K214 E295 C329 E428 P513 1.2.1.88 0003842,0004029,0005739,0005759,0005829,0006560,0010133,0016491,0016620,0042802 Q8CHT0 22868767 601 HMLRWKHTSSLKVANEPILAFSQGSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYM 4e3x B 1.24 BS01 PRO A 1 K292 A525 K275 A508 N211 K233 E314 C348 E447 P532 N194 K216 E297 C331 E430 P515 1.2.1.88 0003842,0004029,0005739,0005759,0005829,0006560,0010133,0016491,0016620,0042802 Q8CHT0 22868767 601 GSHMLRWKHTSSLKVANEPILAFSQGSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYMQ 4e3x B 1.24 BS02 PRO B 1 L302 D303 F305 T307 F308 L285 D286 F288 T290 F291 N211 K233 E314 C348 E447 P532 N194 K216 E297 C331 E430 P515 1.2.1.88 0003842,0004029,0005739,0005759,0005829,0006560,0010133,0016491,0016620,0042802 Q8CHT0 22868767 601 GSHMLRWKHTSSLKVANEPILAFSQGSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYMQ 4e3x B 1.24 BS03 PRO B 2 F210 D393 F193 D376 N211 K233 E314 C348 E447 P532 N194 K216 E297 C331 E430 P515 1.2.1.88 0003842,0004029,0005739,0005759,0005829,0006560,0010133,0016491,0016620,0042802 Q8CHT0 22868767 602 GSHMLRWKHTSSLKVANEPILAFSQGSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYMQ 4e3x B 1.24 BS04 PRO B 3 F212 C348 S349 G512 S513 F520 F195 C331 S332 G495 S496 F503 N211 K233 E314 C348 E447 P532 N194 K216 E297 C331 E430 P515 1.2.1.88 0003842,0004029,0005739,0005759,0005829,0006560,0010133,0016491,0016620,0042802 Q8CHT0 22868767 603 GSHMLRWKHTSSLKVANEPILAFSQGSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYMQ 4k87 A 2.301 BS03 PRO A 1 T121 E123 W169 E171 H173 F216 H242 S272 W273 T106 E108 W154 E156 H158 F201 H227 S257 W258 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 24100331 603 LEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQSMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 4n1m A 1.15 BS02 PRO A 1 R55 Q63 F113 R58 Q66 F116 R55 F60 Q63 N102 F113 L122 H126 R58 F63 Q66 N105 F116 L125 H129 5.2.1.8 0000413,0001933,0001934,0003723,0003755,0005178,0005515,0005576,0005615,0005634,0005737,0005829,0005925,0006457,0006469,0006915,0016018,0016020,0019076,0030168,0030182,0030593,0030595,0031982,0032148,0032873,0032991,0034389,0034599,0034774,0035307,0042118,0043410,0045069,0045070,0046790,0050714,0051082,0051092,0060352,0061944,0070062,0070527,1902176,1903901,1904399,1904813,2001233 P62937 202 SHMMVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4p7w A 1.8 BS03 PRO A 1 Y32 F35 R93 D108 R118 Y32 F35 R93 D108 R118 1.14.11.56 0016706,0018193,0046872,0051213 Q989T9 25171735 303 ATTRILGVVQLDQRRLTDDLAVLAKSNFSSEYSDFACGRWEFCMLRNQSGKQEEQRVVVHETPALATPLGQSLPYLNELLDNHFDRDSIRYARIIRISENACIIPHRDYLELEGKFIRVHLVLDTNEKCSNTEENNIFHMGRGEIWFLDASLPHSAGCFSPTPRLHLVVDIEGTRSLEEVAINVEQPSARNATVDTRKEWTDETLESVLGFSEIISEANYREIVAILAKLHFFHKVHCVDMYGWLKEICRRRGEPALIEKANSLERFYLIDRAAGEVMTY 4qg6 A 3.207 BS01 PRO A 1 N44 N70 H464 I469 N21 N47 H339 I344 R73 K270 T328 R50 K145 T203 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003723,0003729,0003824,0004713,0004743,0005515,0005524,0005576,0005634,0005737,0005739,0005791,0005829,0005929,0006096,0006417,0012501,0016301,0016310,0023026,0030955,0031982,0032869,0034774,0045296,0046872,0061621,0062023,0070062,1903561,1903672,1904813,2000767 P14618 25645022 1001 DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILERPVAVALDTKGPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4qg6 B 3.207 BS01 PRO B 1 G46 H464 I469 F470 G23 H435 I440 F441 R73 R120 K270 T328 R50 R97 K241 T299 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003723,0003729,0003824,0004713,0004743,0005515,0005524,0005576,0005634,0005737,0005739,0005791,0005829,0005929,0006096,0006417,0012501,0016301,0016310,0023026,0030955,0031982,0032869,0034774,0045296,0046872,0061621,0062023,0070062,1903561,1903672,1904813,2000767 P14618 25645022 1001 DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILERPVAVALDTKGPEIRTGLIKAEVEKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4qg6 C 3.207 BS01 PRO C 1 N44 N70 H464 I469 F470 N21 N47 H339 I344 F345 R73 K270 T328 R50 K145 T203 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003723,0003729,0003824,0004713,0004743,0005515,0005524,0005576,0005634,0005737,0005739,0005791,0005829,0005929,0006096,0006417,0012501,0016301,0016310,0023026,0030955,0031982,0032869,0034774,0045296,0046872,0061621,0062023,0070062,1903561,1903672,1904813,2000767 P14618 25645022 1001 DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILERPVAVALDTKGPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4qg6 D 3.207 BS01 PRO D 1 N44 N70 H464 I469 F470 N21 N47 H438 I443 F444 R73 R120 K270 T328 R50 R97 K244 T302 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003723,0003729,0003824,0004713,0004743,0005515,0005524,0005576,0005634,0005737,0005739,0005791,0005829,0005929,0006096,0006417,0012501,0016301,0016310,0023026,0030955,0031982,0032869,0034774,0045296,0046872,0061621,0062023,0070062,1903561,1903672,1904813,2000767 P14618 25645022 1001 DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILERPVAVALDTKGPEIRTGLIKGAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4rdc A 1.198 BS01 PRO A 1 L131 S132 S153 N154 T155 F204 D280 F331 L79 S80 S101 N102 T103 F152 D228 F279 ? 0046872 Q3MFZ5 501 NTIPIGIALAQTSNVALLGQEQVAGAKIAEKYFNDKGGVNGTPIKLIFQDTAGDEAGTINAFQTLINKDKVVGIVGPTLSQQAFSANPIAERAKVPVVGPSNTAKGIPEIGDYVARVSAPVSVVAPNSVKAALKQNPNIKKVAVFFAQNDAFSKSETEIFQQTVKDQGLELVTVQKFQTTDTDFQSQATNAINLKPDLVIISGLAADGGNLVRQLRELGYQGAIIGGDGLNTSNVFAVCKALCDGVLIAQAYSPEYTGEINKAFRQAYVDQYKKEPPQFSAQAFAAVQVYVESLKALDTKNKVSKIQLPELRTELNKQLLTGKYNTPLGEISFTPIGEVVQKDFYVAQIKMEKDGSQGKFTFLK 4ufb A 1.8 BS02 PRO A 1 Q259 F435 K489 H491 Y498 Y501 Q254 F430 K484 H486 Y493 Y496 H331 A332 H361 E362 H365 E389 H491 Y501 H326 A327 H356 E357 H360 E384 H486 Y496 3.4.15.1 0006508,0008237,0008241,0016020 Ki=86000nM P12821 26403559 1304 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLTCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYP 4ufb B 1.8 BS02 PRO B 1 Q259 F435 K489 H491 Y498 Y501 Q256 F432 K486 H488 Y495 Y498 H331 A332 H361 E362 H365 E389 H491 Y501 H328 A329 H358 E359 H362 E386 H488 Y498 3.4.15.1 0006508,0008237,0008241,0016020 Ki=86000nM P12821 26403559 1304 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYP 4ufb C 1.8 BS02 PRO C 1 Q259 F435 K489 H491 Y498 Y501 Q256 F432 K486 H488 Y495 Y498 H331 A332 H361 E362 H365 E389 H491 Y501 H328 A329 H358 E359 H362 E386 H488 Y498 3.4.15.1 0006508,0008237,0008241,0016020 Ki=86000nM P12821 26403559 1304 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEG 4ufb D 1.8 BS02 PRO D 1 Q259 K489 H491 Y498 Y501 Q256 K486 H488 Y495 Y498 H331 A332 H361 E362 H365 E389 H491 Y501 H328 A329 H358 E359 H362 E386 H488 Y498 3.4.15.1 0006508,0008237,0008241,0016020 Ki=86000nM P12821 26403559 1304 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGID 4wn9 B 1.9 BS02 PRO B 1 Y30 F178 V179 G180 F411 K424 Y30 F178 V179 G180 F411 K424 C106 T110 C106 T110 1.18.6.1 0005524,0009399,0016163,0016491,0016612,0046872,0051536 P11347 25710326 502 MLDATPKEIVERKALRINPAKTCQPVGAMYAALGIHNCLPHSHGSQGCCSYHRTVLSRHFKEPAMASTSSFTEGASVFGGGSNIKTAVKNIFSLYNPDIIAVHTTCLSETLGDDLPTYISQMEDAGSIPEGKLVIHTNTPSYVGSHVTGFANMVQGIVNYLSENTGAKNGKINVIPGFVGPADMREIKRLFEAMDIPYIMFPDTSGVLDGPTTGEYKMYPEGGTKIEDLKDTGNSDLTLSLGSYASDLGAKTLEKKCKVPFKTLRTPIGVSATDEFIMALSEATGKEVPASIEEERGQLIDLMIDAQQYLQGKKVALLGDPDEIIALSKFIIELGAIPKYVVTGTPGMKFQKEIDAMLAEAGIEGSKVKVEGDFFDVHQWIKNEGVDLLISNTYGKFIAREENIPFVRFGFPIMDRYGHYYNPKVGYKGAIRLVEEITNVILDKIERECTEEDFEVVR 4wn9 D 1.9 BS04 PRO D 1 Y30 H59 F60 F178 V179 G180 K424 Y30 H59 F60 F178 V179 G180 K424 C106 T110 C106 T110 1.18.6.1 0005524,0009399,0016163,0016491,0016612,0046872,0051536 P11347 25710326 502 MLDATPKEIVERKALRINPAKTCQPVGAMYAALGIHNCLPHSHGSQGCCSYHRTVLSRHFKEPAMASTSSFTEGASVFGGGSNIKTAVKNIFSLYNPDIIAVHTTCLSETLGDDLPTYISQMEDAGSIPEGKLVIHTNTPSYVGSHVTGFANMVQGIVNYLSENTGAKNGKINVIPGFVGPADMREIKRLFEAMDIPYIMFPDTSGVLDGPTTGEYKMYPEGGTKIEDLKDTGNSDLTLSLGSYASDLGAKTLEKKCKVPFKTLRTPIGVSATDEFIMALSEATGKEVPASIEEERGQLIDLMIDAQQYLQGKKVALLGDPDEIIALSKFIIELGAIPKYVVTGTPGMKFQKEIDAMLAEAGIEGSKVKVEGDFFDVHQWIKNEGVDLLISNTYGKFIAREENIPFVRFGFPIMDRYGHYYNPKVGYKGAIRLVEEITNVILDKIERECTEEDFEVVR 4y48 A 1.249 BS02 PRO A 1 G72 T74 D88 G72 T74 D88 D35 S38 D40 W42 Y79 D219 T222 D35 S38 D40 W42 Y79 D219 T222 3.4.23.22 0004190,0006508 P11838 27139825 413 STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK 5bsh A 2.1 BS01 PRO A 1 V236 S238 T242 T243 V234 S236 T240 T241 1.5.1.2 0000166,0004735,0006561,0016491,0055129 G7KRM5 26579138 301 IIPIPADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKTAIHSNPARRTAFESIGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFIRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSGPAYIYLAIEALADGGVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQLKDDVTSPGGTTIAGVHELEKAGFRGILMNAVVAAAKRSQELS 5bsh B 2.1 BS01 PRO B 1 S238 G241 T242 T243 S236 G239 T240 T241 1.5.1.2 0000166,0004735,0006561,0016491,0055129 G7KRM5 26579138 301 IIPIPADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKTAIHSNPARRTAFESIGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFIRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSGPAYIYLAIEALADGGVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQLKDDVTSPGGTTIAGVHELEKAGFRGILMNAVVAAAKRSQELS 5bsh C 2.1 BS01 PRO C 1 V236 S238 G241 T242 T243 V230 S232 G235 T236 T237 1.5.1.2 0000166,0004735,0006561,0016491,0055129 G7KRM5 26579138 301 PIPADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKTASNPARRTAFESIGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFIRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSGPAYIYLAIEALADGGVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQLKDDVTSPGGTTIAGVHELEKAGFRGILMNAVVAAAKRSQELS 5bsh D 2.1 BS01 PRO D 1 V236 S238 T242 T243 V230 S232 T236 T237 1.5.1.2 0000166,0004735,0006561,0016491,0055129 G7KRM5 26579138 301 PIPADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKTASNPARRTAFESIGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFIRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSGPAYIYLAIEALADGGVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQLKDDVTSPGGTTIAGVHELEKAGFRGILMNAVVAAAKRSQELS 5bsh E 2.1 BS01 PRO E 1 S238 T242 T243 S236 T240 T241 1.5.1.2 0000166,0004735,0006561,0016491,0055129 G7KRM5 26579138 301 IIPIPADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKTAIHSNPARRTAFESIGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFIRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSGPAYIYLAIEALADGGVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQLKDDVTSPGGTTIAGVHELEKAGFRGILMNAVVAAAKRSQELS 5bsh F 2.1 BS01 PRO F 1 V236 S238 G241 T242 T243 V234 S236 G239 T240 T241 1.5.1.2 0000166,0004735,0006561,0016491,0055129 G7KRM5 26579138 301 IIPIPADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKTAIHSNPARRTAFESIGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFIRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSGPAYIYLAIEALADGGVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQLKDDVTSPGGTTIAGVHELEKAGFRGILMNAVVAAAKRSQELS 5bsh G 2.1 BS01 PRO G 1 S238 G241 T242 T243 S227 G230 T231 T232 1.5.1.2 0000166,0004735,0006561,0016491,0055129 G7KRM5 26579138 301 PADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKTAARRTAFESIGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFIRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSGPAYIYLAIEALADGGVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQLKDDVTSPGGTTIAGVHELEKAGFRGILMNAVVAAAKRSQELS 5bsh H 2.1 BS01 PRO H 1 S238 T242 T243 S236 T240 T241 1.5.1.2 0000166,0004735,0006561,0016491,0055129 G7KRM5 26579138 301 IIPIPADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKTAIHSNPARRTAFESIGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFIRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSGPAYIYLAIEALADGGVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQLKDDVTSPGGTTIAGVHELEKAGFRGILMNAVVAAAKRSQELS 5bsh I 2.1 BS01 PRO I 1 S238 T242 T243 S234 T238 T239 1.5.1.2 0000166,0004735,0006561,0016491,0055129 G7KRM5 26579138 301 PIPADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKTAIHSNPARRTAFESIGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFIRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSGPAYIYLAIEALADGGVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQLKDDVTSPGGTTIAGVHELEKAGFRGILMNAVVAAAKRSQELS 5bsh J 2.1 BS01 PRO J 1 V236 S238 T242 T243 V233 S235 T239 T240 1.5.1.2 0000166,0004735,0006561,0016491,0055129 G7KRM5 26579138 301 IPIPADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKTAIHSNPARRTAFESIGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFIRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSGPAYIYLAIEALADGGVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQLKDDVTSPGGTTIAGVHELEKAGFRGILMNAVVAAAKRSQELS 5cyh A 2.1 BS02 PRO A 1 R55 Q63 F113 R54 Q62 F112 R55 F60 Q63 N102 F113 L122 H126 R54 F59 Q62 N101 F112 L121 H125 5.2.1.8 0000413,0001933,0001934,0003723,0003755,0005178,0005515,0005576,0005615,0005634,0005737,0005829,0005925,0006457,0006469,0006915,0016018,0016020,0019076,0030168,0030182,0030593,0030595,0031982,0032148,0032873,0032991,0034389,0034599,0034774,0035307,0042118,0043410,0045069,0045070,0046790,0050714,0051082,0051092,0060352,0061944,0070062,0070527,1902176,1903901,1904399,1904813,2001233 P62937 8652512 202 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 5d7i A 2.0 BS01 PRO A 1 Q268 V269 Q262 V263 ? Q95460 26795251 301 RTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELLYSCHVEHSGVHMVLQV 5dis C 2.85 BS01 PRO C 1 R129 K144 W276 R109 K124 W253 ? 0005634,0005737,0006606,0061015,0061608 O95149 26489467 301 GSMEELSQALASSFSVSQDLNSTAAPHPRLKSKYSSLEQSERRRRLLELQKSKRLDYVNHARRLAEDDWTGMKLPKHYANQLMLSEWLIDVPSDLGQEWIVVVCPVGKRALIVASRGSTSAYTKSGYCVNRFSSLLPGGNRRAKDYTILDCIYNEVNQTYYVLDVMCWRGHPFYDCQTDFRFYWMHSKLPEEEGLGEKTKLNPFKFVGLKNFPCTPESLCDVLSMDFPFEVDGLLFYHKQTHYSPGSTPLVGWLRPYMVSDVLG 5f9y A 2.8 BS01 PRO A 1 T300 E302 W348 F395 H421 W450 G451 T112 E114 W160 F207 H233 W262 G263 E302 R331 H352 E114 R143 H164 0000166,0004812,0004827,0005524,0005737,0006418,0006433 700 AHHHHHHSKENESLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETSPEVAWVTKSSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSY 5f9y B 2.8 BS01 PRO B 1 T300 E302 W348 E350 H352 F395 H421 S449 W450 T97 E99 W145 E147 H149 F192 H218 S246 W247 E302 R331 H352 E99 R128 H149 0000166,0004812,0004827,0005524,0005737,0006418,0006433 700 SLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLEEVAWVTKSSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARGAMKSLCIPNDQIFTKCFFCDKLAKKFTLFGRSY 5h29 A 2.3 BS01 PRO A 1 K369 Q467 K16 Q114 ? Q830N9 28935609 603 WFPESMRQQLSGIFAKLTKKVTLLQFLDASDEKSLELQSFLTEFASLDQKITLETILKDTEPAKELLYGIEKMPSVVLLDAAGNYTGIKFSGIPSGHEVNSLVLAVYNVGSEGQPLEASLQKNILALPKRKIEIFVSLTCHFCPDVVAACQRIASINPHVEAEMVDISLFPELKKEKKIMSVPAMLIDGEQMIFGSKTMTEIIEALA 5ifm A 2.6 BS01 PRO A 1 P156 Q157 F218 R220 P104 Q105 F166 R168 ? 0003676,0003723 Q15233 27303796 402 EGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHE 5ifm C 2.6 BS01 PRO C 1 P156 Q157 F218 P104 Q105 F166 ? 0003676,0003723 Q15233 27303796 403 EGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQ 5ihk A 1.35 BS01 PRO A 1 S19 E22 W41 S14 E17 W36 ? P07751 102 KELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVADRQGFVPAAYVKKL 5inr A 1.652 BS02 PRO A 1 C9 N191 Y243 C1 N183 Y235 0006508,0016805,0070004 502 CTSILVGKKASIDGSTLISRNDDGHEALDPQRFVVVNPEDQPRDYTSVISKVNVKLPDDPQRYTSIPNSILTNGIWPAAGINSSNVAMSATETITTNSRVQGLDPFVENGLGEEDLVTVVLPYVKSAREGVKRLGSLLEEYGTYEPNGISFADNEEVWWLETIGGHHWAAVRIPDDAYVVAPNRMNIDQFDFDSDDTLCSSDLKDLIDNNNLNPDFENYNLRHIFGSASIKDTVYNNPRTWYGQKFFSPDDTADDPMEQDLPFICHANRKISVEDVKFVLSSHFENTKYDVYGSGSQSDKTLFRPIGINRNHNVHILQIRNNVPTEIAGIHWLAYGANTFNTVVPFYANVNDTPVQYKNATGKFDLNNMYWLSCTTALLGDTDYDFYVDMRNDYELDAMSAYRKIQNDTDADISGQKDIEKYLENANKKLADVAFEKQNKLLGDMVTTGSNNMKLRYNLND 5inr B 1.652 BS02 PRO B 1 C9 N191 Y243 C1 N183 Y235 0006508,0016805,0070004 502 CTSILVGKKASIDGSTLISRNDDGHEALDPQRFVVVNPEDQPRDYTSVISKVNVKLPDDPQRYTSIPNSILTNGIWPAAGINSSNVAMSATETITTNSRVQGLDPFVENGLGEEDLVTVVLPYVKSAREGVKRLGSLLEEYGTYEPNGISFADNEEVWWLETIGGHHWAAVRIPDDAYVVAPNRMNIDQFDFDSDDTLCSSDLKDLIDNNNLNPDFENYNLRHIFGSASIKDTVYNNPRTWYGQKFFSPDDTADDPMEQDLPFICHANRKISVEDVKFVLSSHFENTKYDVYGSGSQSDKTLFRPIGINRNHNVHILQIRNNVPTEIAGIHWLAYGANTFNTVVPFYANVNDTPVQYKNATGKFDLNNMYWLSCTTALLGDTDYDFYVDMRNDYELDAMSAYRKIQNDTDADISGQKDIEKYLENANKKLADVAFEKQNKLLGDMVTTGSNNMKLRYNLND 5inr C 1.652 BS02 PRO C 1 N191 Y243 N183 Y235 0006508,0016805,0070004 502 CTSILVGKKASIDGSTLISRNDDGHEALDPQRFVVVNPEDQPRDYTSVISKVNVKLPDDPQRYTSIPNSILTNGIWPAAGINSSNVAMSATETITTNSRVQGLDPFVENGLGEEDLVTVVLPYVKSAREGVKRLGSLLEEYGTYEPNGISFADNEEVWWLETIGGHHWAAVRIPDDAYVVAPNRMNIDQFDFDSDDTLCSSDLKDLIDNNNLNPDFENYNLRHIFGSASIKDTVYNNPRTWYGQKFFSPDDTADDPMEQDLPFICHANRKISVEDVKFVLSSHFENTKYDVYGSGSQSDKTLFRPIGINRNHNVHILQIRNNVPTEIAGIHWLAYGANTFNTVVPFYANVNDTPVQYKNATGKFDLNNMYWLSCTTALLGDTDYDFYVDMRNDYELDAMSAYRKIQNDTDADISGQKDIEKYLENANKKLADVAFEKQNKLLGDMVTTGSNNMKLRYNLND 5inr D 1.652 BS02 PRO D 1 C9 N191 Y243 C1 N183 Y235 0006508,0016805,0070004 502 CTSILVGKKASIDGSTLISRNDDGHEALDPQRFVVVNPEDQPRDYTSVISKVNVKLPDDPQRYTSIPNSILTNGIWPAAGINSSNVAMSATETITTNSRVQGLDPFVENGLGEEDLVTVVLPYVKSAREGVKRLGSLLEEYGTYEPNGISFADNEEVWWLETIGGHHWAAVRIPDDAYVVAPNRMNIDQFDFDSDDTLCSSDLKDLIDNNNLNPDFENYNLRHIFGSASIKDTVYNNPRTWYGQKFFSPDDTADDPMEQDLPFICHANRKISVEDVKFVLSSHFENTKYDVYGSGSQSDKTLFRPIGINRNHNVHILQIRNNVPTEIAGIHWLAYGANTFNTVVPFYANVNDTPVQYKNATGKFDLNNMYWLSCTTALLGDTDYDFYVDMRNDYELDAMSAYRKIQNDTDADISGQKDIEKYLENANKKLADVAFEKQNKLLGDMVTTGSNNMKLRYNLND 5inr E 1.652 BS02 PRO E 1 T101 N191 Y243 T93 N183 Y235 0006508,0016805,0070004 502 CTSILVGKKASIDGSTLISRNDDGHEALDPQRFVVVNPEDQPRDYTSVISKVNVKLPDDPQRYTSIPNSILTNGIWPAAGINSSNVAMSATETITTNSRVQGLDPFVENGLGEEDLVTVVLPYVKSAREGVKRLGSLLEEYGTYEPNGISFADNEEVWWLETIGGHHWAAVRIPDDAYVVAPNRMNIDQFDFDSDDTLCSSDLKDLIDNNNLNPDFENYNLRHIFGSASIKDTVYNNPRTWYGQKFFSPDDTADDPMEQDLPFICHANRKISVEDVKFVLSSHFENTKYDVYGSGSQSDKTLFRPIGINRNHNVHILQIRNNVPTEIAGIHWLAYGANTFNTVVPFYANVNDTPVQYKNATGKFDLNNMYWLSCTTALLGDTDYDFYVDMRNDYELDAMSAYRKIQNDTDADISGQKDIEKYLENANKKLADVAFEKQNKLLGDMVTTGSNNMKLRYNLND 5m4j A 1.55 BS02 PRO A 1 H255 H377 R398 E412 R450 H250 H372 R393 E407 R445 D60 H255 D276 D287 H366 H370 H377 E412 Y416 R450 E452 D55 H250 D271 D282 H361 H365 H372 E407 Y411 R445 E447 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 28677335 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 5m4j B 1.55 BS02 PRO B 1 H255 H377 R398 E412 R450 H250 H372 R393 E407 R445 D60 H255 D276 D287 H366 H370 H377 E412 Y416 R450 E452 D55 H250 D271 D282 H361 H365 H372 E407 Y411 R445 E447 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 28677335 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 5m4l A 1.49 BS05 PRO A 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 D60 H255 D276 D287 H366 H370 H377 E412 Y416 R450 E452 D55 H250 D271 D282 H361 H365 H372 E407 Y411 R445 E447 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 28677335 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 5m4l B 1.49 BS05 PRO B 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 D60 H255 D276 D287 H366 H370 H377 E412 Y416 R450 E452 D55 H250 D271 D282 H361 H365 H372 E407 Y411 R445 E447 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 28677335 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 5m4q A 1.73 BS04 PRO A 1 H255 H366 R398 E412 H250 H361 R393 E407 D60 H255 D276 D287 H366 H370 H377 E412 Y416 R450 E452 D55 H250 D271 D282 H361 H365 H372 E407 Y411 R445 E447 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 Ki=0.31mM -logKd/Ki=3.51, Ki=0.31mM P12955 28677335 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 5m4q B 1.73 BS04 PRO B 1 H255 H366 R398 E412 R450 H250 H361 R393 E407 R445 D60 H255 D276 D287 H366 H370 H377 E412 Y416 R450 E452 D55 H250 D271 D282 H361 H365 H372 E407 Y411 R445 E447 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 Ki=0.31mM -logKd/Ki=3.51, Ki=0.31mM P12955 28677335 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCD 5mby A 1.55 BS04 PRO A 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 -logKd/Ki=3.51, Ki=0.31mM P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECQVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDAFTPFS 5mby B 1.55 BS04 PRO B 1 H255 H366 H377 R398 E412 H250 H361 H372 R393 E407 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 -logKd/Ki=3.51, Ki=0.31mM P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECQVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDAFTPF 5mbz A 1.5 BS04 PRO A 1 H255 H366 H377 R398 E412 H247 H358 H369 R390 E404 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKIFSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 5mbz B 1.5 BS04 PRO B 1 H255 H366 H377 R398 E412 H247 H356 H367 R388 E402 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKIFSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSCICGSGENSAVLHYAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTP 5mc0 A 1.56 BS04 PRO A 1 H254 H365 H376 R397 E411 R449 H249 H360 H371 R392 E406 R444 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDK 5mc0 B 1.56 BS04 PRO B 1 H254 H365 H376 R397 E411 R449 H249 H360 H371 R392 E406 R444 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAF 5mc1 A 1.43 BS03 PRO A 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFNMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 5mc1 B 1.43 BS03 PRO B 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFNMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPFS 5mc2 A 1.7 BS03 PRO A 1 H255 H366 H377 R398 E412 R450 H248 H355 H366 R387 E401 R439 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYICGSGENSAVLHYAPNDRTIQNGDMCLFDMDGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFT 5mc2 B 1.7 BS03 PRO B 1 H366 H377 R398 E412 H357 H368 R389 E403 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYICGSGSAVLHYGHAGAPNDRTIQNGDMCLFDMDGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTP 5mc3 A 1.52 BS03 PRO A 1 H255 H366 R398 R450 H250 H361 R393 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVKPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCAFTPF 5mc3 B 1.52 BS03 PRO B 1 H255 H366 R398 R450 H250 H361 R393 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVKPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 5mc4 A 1.8 BS04 PRO A 1 H366 H377 R398 E412 H348 H359 R380 E394 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGRVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCD 5mc4 B 1.8 BS04 PRO B 1 H366 H377 R398 H352 H363 R384 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGRVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFT 5mc5 A 1.9 BS04 PRO A 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEDVVVTDSGIELLTCVPRTVEEIEACMAGCD 5mc5 B 1.9 BS04 PRO B 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEDVVVTDSGIELLTCVPRTVEEIEACMAGCDK 5o1o A 2.48 BS01 PRO A 1 D604 R726 D124 R246 D604 D124 1.5.1.8,1.5.1.9 Q9UDR5 1002 RKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMESIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTLLRGTLRYKGYMKALNGFVKLGLINREALPNPLTWKQLLCDLVGISPSSEHDVLKEAVLKKLGGDNTQLEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRDSFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFSKEIYGPILERIKAEGIIYTTQSTIK 5o1o B 2.48 BS01 PRO B 1 D604 G635 T724 R726 D124 G155 T244 R246 D604 D124 1.5.1.8,1.5.1.9 Q9UDR5 1002 RKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMESIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTLLRGTLRYKGYMKALNGFVKLGLINREALPPLTWKQLLCDLVSSEHDVLKEAVLKKLGGDNTQLEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRDSFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFSKEIYGPILERIKAEGIIYTTQSTIKP 5orf A 2.54 BS01 PRO A 1 A576 Q579 A580 A576 Q579 A580 ? 0005576,0005615,0005737,0008289,0046872,0072562,1903981 P14639 29095162 604 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf A 2.54 BS02 PRO A 2 P303 A306 P303 A306 ? 0005576,0005615,0005737,0008289,0046872,0072562,1903981 P14639 29095162 606 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf B 2.54 BS01 PRO B 1 L301 P302 L301 P302 ? 0005576,0005615,0005737,0008289,0046872,0072562,1903981 P14639 29095162 604 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf C 2.54 BS01 PRO C 1 N18 V282 L283 N18 V282 L283 ? 0005576,0005615,0005737,0008289,0046872,0072562,1903981 P14639 29095162 604 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf C 2.54 BS02 PRO C 2 P119 D120 E171 D172 K173 G174 P119 D120 E171 D172 K173 G174 ? 0005576,0005615,0005737,0008289,0046872,0072562,1903981 P14639 29095162 605 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf D 2.54 BS01 PRO D 1 N300 L301 P302 N300 L301 P302 ? 0005576,0005615,0005737,0008289,0046872,0072562,1903981 P14639 29095162 602 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf D 2.54 BS02 PRO D 2 A405 R409 R412 A405 R409 R412 ? 0005576,0005615,0005737,0008289,0046872,0072562,1903981 P14639 29095162 603 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5otb A 2.5 BS01 PRO A 1 A209 W213 S343 L346 V481 A207 W211 S341 L344 V479 ? 0005576,0005615,0005737,0008289,0046872,0072562 B3VHM9 29095162 602 HKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDTLSSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFLLEGPKLVASTQAALA 5otb A 2.5 BS02 PRO A 2 E16 E17 Q20 E14 E15 Q18 ? 0005576,0005615,0005737,0008289,0046872,0072562 B3VHM9 29095162 603 HKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDTLSSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFLLEGPKLVASTQAALA 5otb B 2.5 BS01 PRO B 1 E17 K131 W134 E15 K129 W132 ? 0005576,0005615,0005737,0008289,0046872,0072562 B3VHM9 29095162 602 HKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDTLSSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFLLEGPKLVASTQAALA 5otb B 2.5 BS02 PRO B 2 P302 P303 P300 P301 ? 0005576,0005615,0005737,0008289,0046872,0072562 B3VHM9 29095162 603 HKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDTLSSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFLLEGPKLVASTQAALA 5otb C 2.5 BS01 PRO C 1 E17 K131 W134 N161 E15 K129 W132 N159 ? 0005576,0005615,0005737,0008289,0046872,0072562 B3VHM9 29095162 603 HKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDTLSSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFLLEGPKLVASTQAALA 5otb C 2.5 BS02 PRO C 2 N390 L429 V432 N388 L427 V430 ? 0005576,0005615,0005737,0008289,0046872,0072562 B3VHM9 29095162 604 HKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDTLSSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFLLEGPKLVASTQAALA 5otb C 2.5 BS03 PRO C 3 V297 E299 V295 E297 ? 0005576,0005615,0005737,0008289,0046872,0072562 B3VHM9 29095162 605 HKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDTLSSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFLLEGPKLVASTQAALA 5otb D 2.5 BS01 PRO D 1 E17 E130 K131 W134 E15 E128 K129 W132 ? 0005576,0005615,0005737,0008289,0046872,0072562 B3VHM9 29095162 602 HKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDTLSSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFLLEGPKLVASTQAALA 5otb D 2.5 BS02 PRO D 2 W213 R217 D450 W211 R215 D448 ? 0005576,0005615,0005737,0008289,0046872,0072562 B3VHM9 29095162 603 HKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDTLSSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFLLEGPKLVASTQAALA 5otb D 2.5 BS03 PRO D 3 P467 V468 E470 P465 V466 E468 ? 0005576,0005615,0005737,0008289,0046872,0072562 B3VHM9 29095162 605 HKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDTLSSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFLLEGPKLVASTQAALA 5t88 A 1.902 BS03 PRO A 1 Y401 S477 N478 R562 Y401 S477 N478 R562 Y401 S477 D560 H592 Y401 S477 D560 H592 3.4.21.26 0004252,0005829,0006508,0008236,0070012 Q51714 30786206 709 MEDPYIWMENLEDERVLKIIEEENKRFREFIGELSDKLFPEVWEQFSQPTIGMARITKKGIIASYSEKDRVVIKWFNGDVIVDSKELEREVGDEVLLQGFTTDEEGEKLAYSFSIGGADEGITRIIDLKTGEVIEEIKPSIWNITFLKDGYYFTRFYRKEKTPDGVNPPAARMFWKDREGERMVFGEGLTSGYFMSIRKSSDGKFAIVTLTYGWNQGEVYIGPIDNPQEWKKVYSASVPVEAIDVVNGKLYILTKEGKGLGKIIAIKNGKIDEVIPEGEFPLEWAVIVRDKILAGRLVHASYKLEVYTLNGEKIKEITFDVPGSLYPLDKDEERVLLRYTSFTIPYRLYEFKDDLRLIEERKVEGEFRVEEDFATSKDGTKVHYFIVKGERDEKRAWVFGYGGFNIALTPMFFPQVIPFLKRGGTFIMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAAWGRSNGGLLVSATLTQRPDVMDSALIGYPVIDMLRFHKLYIGSVWIPEYGNPEDPKDREFLLKYSPYHNVDPKKKYPPTLIYTGLHDDRVHPAHALKFFMKLKEIGAPVYLRVETKSGHMGASPETRARELTDLLAFVLKTLS 5t88 B 1.902 BS03 PRO B 1 W518 R562 W518 R562 Y401 S477 D560 H592 Y401 S477 D560 H592 3.4.21.26 0004252,0005829,0006508,0008236,0070012 Q51714 30786206 709 MEDPYIWMENLEDERVLKIIEEENKRFREFIGELSDKLFPEVWEQFSQPTIGMARITKKGIIASYSEKDRVVIKWFNGDVIVDSKELEREVGDEVLLQGFTTDEEGEKLAYSFSIGGADEGITRIIDLKTGEVIEEIKPSIWNITFLKDGYYFTRFYRKEKTPDGVNPPAARMFWKDREGERMVFGEGLTSGYFMSIRKSSDGKFAIVTLTYGWNQGEVYIGPIDNPQEWKKVYSASVPVEAIDVVNGKLYILTKEGKGLGKIIAIKNGKIDEVIPEGEFPLEWAVIVRDKILAGRLVHASYKLEVYTLNGEKIKEITFDVPGSLYPLDKDEERVLLRYTSFTIPYRLYEFKDDLRLIEERKVEGEFRVEEDFATSKDGTKVHYFIVKGERDEKRAWVFGYGGFNIALTPMFFPQVIPFLKRGGTFIMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAAWGRSNGGLLVSATLTQRPDVMDSALIGYPVIDMLRFHKLYIGSVWIPEYGNPEDPKDREFLLKYSPYHNVDPKKKYPPTLIYTGLHDDRVHPAHALKFFMKLKEIGAPVYLRVETKSGHMGASPETRARELTDLLAFVLKTLS 5t88 B 1.902 BS04 PRO B 2 Y401 F404 S477 N478 W518 R562 Y401 F404 S477 N478 W518 R562 Y401 S477 D560 H592 Y401 S477 D560 H592 3.4.21.26 0004252,0005829,0006508,0008236,0070012 Q51714 30786206 710 MEDPYIWMENLEDERVLKIIEEENKRFREFIGELSDKLFPEVWEQFSQPTIGMARITKKGIIASYSEKDRVVIKWFNGDVIVDSKELEREVGDEVLLQGFTTDEEGEKLAYSFSIGGADEGITRIIDLKTGEVIEEIKPSIWNITFLKDGYYFTRFYRKEKTPDGVNPPAARMFWKDREGERMVFGEGLTSGYFMSIRKSSDGKFAIVTLTYGWNQGEVYIGPIDNPQEWKKVYSASVPVEAIDVVNGKLYILTKEGKGLGKIIAIKNGKIDEVIPEGEFPLEWAVIVRDKILAGRLVHASYKLEVYTLNGEKIKEITFDVPGSLYPLDKDEERVLLRYTSFTIPYRLYEFKDDLRLIEERKVEGEFRVEEDFATSKDGTKVHYFIVKGERDEKRAWVFGYGGFNIALTPMFFPQVIPFLKRGGTFIMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAAWGRSNGGLLVSATLTQRPDVMDSALIGYPVIDMLRFHKLYIGSVWIPEYGNPEDPKDREFLLKYSPYHNVDPKKKYPPTLIYTGLHDDRVHPAHALKFFMKLKEIGAPVYLRVETKSGHMGASPETRARELTDLLAFVLKTLS 5u56 B 2.65 BS01 PRO B 1 Y11 N100 Y12 N101 ? Q5NFG1 28864445 303 AMLLYTKKDDIYSDIVRMILLIKGANAKIVDVSKEENSKHLEELNIITPNGNIPTLSTDDFAVYRLSVIIEAIEDLYPFPPMFPVFPKQRANARILLEYVNKTFLQNIIKLQSPDLDEKQANEIKMLMQRDIISTYKKIVSEREVNAESNPDAQNINVLTLIITFVFYYFIKLKISIPTKDKNIIKEIKELLSEPNFIKTIK 5uau A 1.9 BS01 PRO A 1 S233 A237 T238 S233 A237 T238 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 401 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQ 5uau A 1.9 BS02 PRO A 2 T137 E163 E164 T137 E163 E164 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 402 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQ 5uau B 1.9 BS01 PRO A 1 T171 G175 T174 G178 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 401 FQSMSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQ 5uau B 1.9 BS02 PRO B 1 V231 A237 T238 V234 A240 T241 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 401 FQSMSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQ 5uau B 1.9 BS03 PRO B 2 T137 E163 E164 T140 E166 E167 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 402 FQSMSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQ 5uau C 1.9 BS01 PRO C 1 S233 G236 A237 T238 S231 G234 A235 T236 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 401 SMSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMTVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQ 5uau C 1.9 BS02 PRO C 2 T137 E163 E164 T135 E161 E162 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 402 SMSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMTVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQ 5uau D 1.9 BS01 PRO C 1 T171 G175 T171 G175 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 401 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQE 5uau D 1.9 BS02 PRO D 1 G236 A237 T238 G236 A237 T238 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 401 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQE 5uau D 1.9 BS03 PRO D 2 T137 E163 E164 T137 E163 E164 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 402 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQE 5uau E 1.9 BS01 PRO E 1 S233 G236 A237 T238 S226 G229 A230 T231 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 401 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMLRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQ 5uau E 1.9 BS02 PRO E 2 T137 E163 E164 T130 E156 E157 1.5.1.2 0004735,0005515,0005739,0005759,0006561,0016491,0034599,0042802,0051881,0055129,1903377 P32322 28258219 402 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMLRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQ 5vad A 2.36 BS02 PRO A 1 T1121 E1123 W1169 E1171 F1216 H1242 S1272 W1273 G1274 T106 E108 W154 E156 F201 H227 S257 W258 G259 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 28501621 1602 LEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGILSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTAMGAKSLCIPFKPLCELQPGAKCVCNPAKYYTLFGRSY 5vad B 2.36 BS02 PRO B 1 T1121 E1123 R1152 W1169 E1171 F1216 H1242 W1273 G1274 T106 E108 R137 W154 E156 F201 H227 W258 G259 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 28501621 1602 LEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGILSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARMGAKSLCIPFKPLCELQPGAKCVCNPAKYYTLFGRSY 5wze A 1.783 BS01 PRO A 1 H243 H350 H361 H243 H350 H361 ? 0004177,0005829,0006508,0008237,0030145,0046872,0070006 Q9HTW6 29259588 504 MIRIPKSEYARRRKALMAQMEPNSIAILPAAPMYIRNRDVEHVYRQDSDFQYLTGFPEPEAVMALIPGRAHGEYVLFCRERDPERELWDGLRAGQDGAIGQYGADDAFPIGDIDDILPGLIEGRDRVYYALGANPDFDRRLMDWINVIRSKARQGAQPPNEFVALDHLLHDQRLYKSANEVKVMRYAAEVSARAHIRAMEVCRPGLFEYHLEAELEYEFRKGGAKMPAYGSIVAAGRNACILHYRENDAAIKDGDLILIDAGCEIDCYASDITRTFPANGRFSPEQKAIYELVLEANMAAFDYIAPGRHWNEAHEATVRVITAGLVRLGLLEGDVDELIAHEAYKAFYMHRAGHWLGMDVHDVGEYRVGGEWRVLEPGMAMTVEPGIYIAPDNTTVAKKWRGIGVRIEDDVVVTRNGCEVLTNGVPKTVAEIEALMAAAKSE 5wze B 1.783 BS01 PRO B 1 H243 H350 E384 H243 H350 E384 ? 0004177,0005829,0006508,0008237,0030145,0046872,0070006 Q9HTW6 29259588 506 MIRIPKSEYARRRKALMAQMEPNSIAILPAAPMYIRNRDVEHVYRQDSDFQYLTGFPEPEAVMALIPGRAHGEYVLFCRERDPERELWDGLRAGQDGAIGQYGADDAFPIGDIDDILPGLIEGRDRVYYALGANPDFDRRLMDWINVIRSKARQGAQPPNEFVALDHLLHDQRLYKSANEVKVMRYAAEVSARAHIRAMEVCRPGLFEYHLEAELEYEFRKGGAKMPAYGSIVAAGRNACILHYRENDAAIKDGDLILIDAGCEIDCYASDITRTFPANGRFSPEQKAIYELVLEANMAAFDYIAPGRHWNEAHEATVRVITAGLVRLGLLEGDVDELIAHEAYKAFYMHRAGHWLGMDVHDVGEYRVGGEWRVLEPGMAMTVEPGIYIAPDNTTVAKKWRGIGVRIEDDVVVTRNGCEVLTNGVPKTVAEIEALMAAAKSEAALEHHH 5wze C 1.783 BS01 PRO C 1 H350 H354 E384 H350 H354 E384 ? 0004177,0005829,0006508,0008237,0030145,0046872,0070006 Q9HTW6 29259588 504 MIRIPKSEYARRRKALMAQMEPNSIAILPAAPMYIRNRDVEHVYRQDSDFQYLTGFPEPEAVMALIPGRAHGEYVLFCRERDPERELWDGLRAGQDGAIGQYGADDAFPIGDIDDILPGLIEGRDRVYYALGANPDFDRRLMDWINVIRSKARQGAQPPNEFVALDHLLHDQRLYKSANEVKVMRYAAEVSARAHIRAMEVCRPGLFEYHLEAELEYEFRKGGAKMPAYGSIVAAGRNACILHYRENDAAIKDGDLILIDAGCEIDCYASDITRTFPANGRFSPEQKAIYELVLEANMAAFDYIAPGRHWNEAHEATVRVITAGLVRLGLLEGDVDELIAHEAYKAFYMHRAGHWLGMDVHDVGEYRVGGEWRVLEPGMAMTVEPGIYIAPDNTTVAKKWRGIGVRIEDDVVVTRNGCEVLTNGVPKTVAEIEALMAAAKSE 5wze D 1.783 BS03 PRO D 1 H350 E384 H350 E384 ? 0004177,0005829,0006508,0008237,0030145,0046872,0070006 Q9HTW6 29259588 510 MIRIPKSEYARRRKALMAQMEPNSIAILPAAPMYIRNRDVEHVYRQDSDFQYLTGFPEPEAVMALIPGRAHGEYVLFCRERDPERELWDGLRAGQDGAIGQYGADDAFPIGDIDDILPGLIEGRDRVYYALGANPDFDRRLMDWINVIRSKARQGAQPPNEFVALDHLLHDQRLYKSANEVKVMRYAAEVSARAHIRAMEVCRPGLFEYHLEAELEYEFRKGGAKMPAYGSIVAAGRNACILHYRENDAAIKDGDLILIDAGCEIDCYASDITRTFPANGRFSPEQKAIYELVLEANMAAFDYIAPGRHWNEAHEATVRVITAGLVRLGLLEGDVDELIAHEAYKAFYMHRAGHWLGMDVHDVGEYRVGGEWRVLEPGMAMTVEPGIYIAPDNTTVAKKWRGIGVRIEDDVVVTRNGCEVLTNGVPKTVAEIEALMAAAKSEAA 5xa3 A 2.2 BS02 PRO A 1 P25 Y51 P23 Y49 T268 F393 C400 T266 F391 C398 1.14.14.1,1.6.2.4 0004497,0005506,0016705,0020037 P14779 28544674 504 KEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 5xa3 B 2.2 BS02 PRO B 1 P25 Y51 P23 Y49 T268 F393 C400 T266 F391 C398 1.14.14.1,1.6.2.4 0004497,0005506,0016705,0020037 P14779 28544674 504 KEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 5xa3 C 2.2 BS02 PRO C 1 P25 Y51 M354 P23 Y49 M352 T268 F393 C400 T266 F391 C398 1.14.14.1,1.6.2.4 0004497,0005506,0016705,0020037 P14779 28544674 504 KEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 5xa3 D 2.2 BS02 PRO D 1 P25 Y51 P23 Y49 T268 F393 C400 T266 F391 C398 1.14.14.1,1.6.2.4 0004497,0005506,0016705,0020037 P14779 28544674 504 KEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 5yp3 A 2.44 BS02 PRO A 1 Y527 S613 N614 Y645 Y649 V692 H721 Y506 S592 N593 Y624 Y628 V671 H700 Y527 S613 N614 D689 H721 Y506 S592 N593 D668 H700 3.4.14.5 0006508,0008236 Q6F3I7 29426867 802 AEKLTLEAITGSAPLSGPTLTKPQIAPDGSRVTFLRGKDRDRNRLDLWEYDIASGQTRLLVDSSVVLPGEEVLSDEEKARRERQRIAALSGIVDYQWSPDGKALLFPLGGELYFYDLTKSGRDAVRKLTNGGGFATDPKISPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGSDTIGNGVAEFVADEEMDRHTGYWWAPDDAAIAFARIDETPVPVQKRYEVYPDRTEVVEQRYPAAGDHNVRVQLGVIAPKTGARPRWIDLGKDPDIYLARVDWRDPQRLTFQRQSRDQKKIELIETTLTNGTQRTLVTETSTTWVPLHNDLRFLKDGRFLWSSERSGFEHLYVASEDGSTLTALTQGEWVVDSLLAIDEAAGLAYVSGTRDGATEAHVYAVPLSGGEPRRLTQAPGMHAATFARNASVFVDSWSSDTTLPQIELFKADGTKLATLLVNDVSDATHPYAKYRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQYLAQQGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYMDLPKANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMTYPGAKHGLRGSDLLHRYRLTEDFFARCLKP 5yp3 B 2.44 BS02 PRO B 1 Y527 S613 N614 Y645 Y649 Y506 S592 N593 Y624 Y628 Y527 S613 N614 D689 H721 Y506 S592 N593 D668 H700 3.4.14.5 0006508,0008236 Q6F3I7 29426867 802 AEKLTLEAITGSAPLSGPTLTKPQIAPDGSRVTFLRGKDRDRNRLDLWEYDIASGQTRLLVDSSVVLPGEEVLSDEEKARRERQRIAALSGIVDYQWSPDGKALLFPLGGELYFYDLTKSGRDAVRKLTNGGGFATDPKISPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGSDTIGNGVAEFVADEEMDRHTGYWWAPDDAAIAFARIDETPVPVQKRYEVYPDRTEVVEQRYPAAGDHNVRVQLGVIAPKTGARPRWIDLGKDPDIYLARVDWRDPQRLTFQRQSRDQKKIELIETTLTNGTQRTLVTETSTTWVPLHNDLRFLKDGRFLWSSERSGFEHLYVASEDGSTLTALTQGEWVVDSLLAIDEAAGLAYVSGTRDGATEAHVYAVPLSGGEPRRLTQAPGMHAATFARNASVFVDSWSSDTTLPQIELFKADGTKLATLLVNDVSDATHPYAKYRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQYLAQQGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYMDLPKANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMTYPGAKHGLRGSDLLHRYRLTEDFFARCLKP 5yp3 C 2.44 BS02 PRO C 1 Y527 S613 N614 Y645 Y649 Y506 S592 N593 Y624 Y628 Y527 S613 N614 D689 H721 Y506 S592 N593 D668 H700 3.4.14.5 0006508,0008236 Q6F3I7 29426867 802 AEKLTLEAITGSAPLSGPTLTKPQIAPDGSRVTFLRGKDRDRNRLDLWEYDIASGQTRLLVDSSVVLPGEEVLSDEEKARRERQRIAALSGIVDYQWSPDGKALLFPLGGELYFYDLTKSGRDAVRKLTNGGGFATDPKISPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGSDTIGNGVAEFVADEEMDRHTGYWWAPDDAAIAFARIDETPVPVQKRYEVYPDRTEVVEQRYPAAGDHNVRVQLGVIAPKTGARPRWIDLGKDPDIYLARVDWRDPQRLTFQRQSRDQKKIELIETTLTNGTQRTLVTETSTTWVPLHNDLRFLKDGRFLWSSERSGFEHLYVASEDGSTLTALTQGEWVVDSLLAIDEAAGLAYVSGTRDGATEAHVYAVPLSGGEPRRLTQAPGMHAATFARNASVFVDSWSSDTTLPQIELFKADGTKLATLLVNDVSDATHPYAKYRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQYLAQQGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYMDLPKANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMTYPGAKHGLRGSDLLHRYRLTEDFFARCLKP 5yp3 D 2.44 BS02 PRO D 1 Y527 S613 N614 Y649 Y506 S592 N593 Y628 Y527 S613 N614 D689 H721 Y506 S592 N593 D668 H700 3.4.14.5 0006508,0008236 Q6F3I7 29426867 802 AEKLTLEAITGSAPLSGPTLTKPQIAPDGSRVTFLRGKDRDRNRLDLWEYDIASGQTRLLVDSSVVLPGEEVLSDEEKARRERQRIAALSGIVDYQWSPDGKALLFPLGGELYFYDLTKSGRDAVRKLTNGGGFATDPKISPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGSDTIGNGVAEFVADEEMDRHTGYWWAPDDAAIAFARIDETPVPVQKRYEVYPDRTEVVEQRYPAAGDHNVRVQLGVIAPKTGARPRWIDLGKDPDIYLARVDWRDPQRLTFQRQSRDQKKIELIETTLTNGTQRTLVTETSTTWVPLHNDLRFLKDGRFLWSSERSGFEHLYVASEDGSTLTALTQGEWVVDSLLAIDEAAGLAYVSGTRDGATEAHVYAVPLSGGEPRRLTQAPGMHAATFARNASVFVDSWSSDTTLPQIELFKADGTKLATLLVNDVSDATHPYAKYRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQYLAQQGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYMDLPKANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMTYPGAKHGLRGSDLLHRYRLTEDFFARCLKP 5yp4 A 1.9 BS02 PRO A 1 Y527 S613 N614 Y645 Y649 Y506 S592 N593 Y624 Y628 Y527 S613 N614 D689 H721 Y506 S592 N593 D668 H700 3.4.14.5 0006508,0008236 Q6F3I7 29426867 802 AEKLTLEAITGSAPLSGPTLTKPQIAPDGSRVTFLRGKDRDRNRLDLWEYDIASGQTRLLVDSSVVLPGEEVLSDEEKARRERQRIAALSGIVDYQWSPDGKALLFPLGGELYFYDLTKSGRDAVRKLTNGGGFATDPKISPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGSDTIGNGVAEFVADEEMDRHTGYWWAPDDAAIAFARIDETPVPVQKRYEVYPDRTEVVEQRYPAAGDHNVRVQLGVIAPKTGARPRWIDLGKDPDIYLARVDWRDPQRLTFQRQSRDQKKIELIETTLTNGTQRTLVTETSTTWVPLHNDLRFLKDGRFLWSSERSGFEHLYVASEDGSTLTALTQGEWVVDSLLAIDEAAGLAYVSGTRDGATEAHVYAVPLSGGEPRRLTQAPGMHAATFARNASVFVDSWSSDTTLPQIELFKADGTKLATLLVNDVSDATHPYAKYRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQYLAQQGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYMDLPKANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMTYPGAKHGLRGSDLLHRYRLTEDFFARCLKP 5yp4 B 1.9 BS02 PRO B 1 Y527 S613 N614 Y645 Y649 Y506 S592 N593 Y624 Y628 Y527 S613 N614 D689 H721 Y506 S592 N593 D668 H700 3.4.14.5 0006508,0008236 Q6F3I7 29426867 802 AEKLTLEAITGSAPLSGPTLTKPQIAPDGSRVTFLRGKDRDRNRLDLWEYDIASGQTRLLVDSSVVLPGEEVLSDEEKARRERQRIAALSGIVDYQWSPDGKALLFPLGGELYFYDLTKSGRDAVRKLTNGGGFATDPKISPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGSDTIGNGVAEFVADEEMDRHTGYWWAPDDAAIAFARIDETPVPVQKRYEVYPDRTEVVEQRYPAAGDHNVRVQLGVIAPKTGARPRWIDLGKDPDIYLARVDWRDPQRLTFQRQSRDQKKIELIETTLTNGTQRTLVTETSTTWVPLHNDLRFLKDGRFLWSSERSGFEHLYVASEDGSTLTALTQGEWVVDSLLAIDEAAGLAYVSGTRDGATEAHVYAVPLSGGEPRRLTQAPGMHAATFARNASVFVDSWSSDTTLPQIELFKADGTKLATLLVNDVSDATHPYAKYRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQYLAQQGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYMDLPKANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMTYPGAKHGLRGSDLLHRYRLTEDFFARCLKP 5yp4 C 1.9 BS02 PRO C 1 Y527 S613 N614 Y645 Y649 Y469 S555 N556 Y587 Y591 Y527 S613 N614 D689 H721 Y469 S555 N556 D631 H663 3.4.14.5 0006508,0008236 Q6F3I7 29426867 802 AEKLTLEAITGSAPLSGPTLTKPQIAPDGSRVTFLRGKDRNRLDLWEYDIASGQTRLLVDSSVVLPLSGIVDYQWALLFPLGGELYFYAVRKLTGGFATDPKISPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGSDTIGNGVAEFVADEEMDRHTGYWWAPDDAAIAFARIDETPVPVQKRYEVYPDRTEVVEQRYPAAGDHNVRVQLGVIAPKTGARPRWIDLGKDPDIYLARVDWRDPQRLTFQRQSRDQKKIELIETTLTNGTQRTLVTETSTTWVPLHNDLRFLKDGRFLWSSERSGFEHLYVASEDGSTLTALTQGEWVVDSLLAIDEAAGLAYVSGTRDGATEAHVYAVPLSGGEPRRLTQAPGMHAATFARNASVFVDSWSSDTTLPQIELFKADGTKLATLLVNDVSDATHPYAKYRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQYLAQQGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYMDLPKANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMTYPGAKHGLRGSDLLHRYRLTEDFFARCLKP 5yp4 D 1.9 BS02 PRO D 1 Y527 S613 N614 Y645 Y649 Y496 S582 N583 Y614 Y618 Y527 S613 N614 D689 H721 Y496 S582 N583 D658 H690 3.4.14.5 0006508,0008236 Q6F3I7 29426867 802 AEKLTLEAITGSAPLSGPTLTKPQIAPDGSRVTFLRGKDRDRNRLDLWEYDIASGQTRLLVDSSVVLPGEEVLSDEEKARRERQRIAALSGIVDYQWSPDGKALLFPLGGELYFYDLTKSGRDAVRKLTNGGGFATDPKISPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGSDTIGNGVAEFVADEEMDRHTGYWWAPDDAAIAFARIDETPVPVQKRVEQRYPAAGDHNVRVQLGVIAPKTGARPRWIDLGKDPDIYLARVDWRDPQRLTFQRQSRDQKKIELIETTLTNGTQRTLVTETSTTWVPLHNDLRFLKDGRFLWSSERSGFEHLYVASEDGSTLTALTQGEWVVDSLLAIDEAAGLAYVSGTRDGATEAHVYAVPLSGGEPRRLTQAPGMHAATFARNASVFVDSWSSDTTLPQIELFKADGTKLATLLVNDVSDATHPYAKYRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQYLAQQGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYMDLPKANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMTYPGAKHGLRGSDLLHRYRLTEDFFARCLKP 5yu3 A 1.79 BS02 PRO A 1 M65 K77 R121 M65 K77 R121 4.3.1.12 0000166,0005737,0008473,0016829 D9UBW0 29629557 403 METWVLGRRDVAEVVAAVGRDELMRRIIDRLTGGLAEIGRGERHLSPLRGGLERSEPVPGIWEWMPHREPGDHITLKTVGYSPANPARFGLPTILGTVARYDDTTGALTALMDGVLLTALRTGAASAVASRLLARPDSHTLGLIGTGAQAVTQLHALSLVLPLQRALVWDTDPAHRESFARRAAFTGVSVEIAEPARIAAEADVISTATSVAVGQGPVLPDTGVREHLHINAVGADLVGKTELPLGLLERAFVTADHPEQALREGECQQLSADRLGPQLAHLCADPAAAAGRQDTLSVFDSTGFAFEDALAMEVFLEAAAERDLGIRVGIEHHPGDALDPYALQ 5yu3 B 1.79 BS02 PRO B 1 E63 M65 K77 R121 E63 M65 K77 R121 4.3.1.12 0000166,0005737,0008473,0016829 D9UBW0 29629557 403 METWVLGRRDVAEVVAAVGRDELMRRIIDRLTGGLAEIGRGERHLSPLRGGLERSEPVPGIWEWMPHREPGDHITLKTVGYSPANPARFGLPTILGTVARYDDTTGALTALMDGVLLTALRTGAASAVASRLLARPDSHTLGLIGTGAQAVTQLHALSLVLPLQRALVWDTDPAHRESFARRAAFTGVSVEIAEPARIAAEADVISTATSVAVGQGPVLPDTGVREHLHINAVGADLVGKTELPLGLLERAFVTADHPEQALREGECQQLSADRLGPQLAHLCADPAAAAGRQDTLSVFDSTGFAFEDALAMEVFLEAAAERDLGIRVGIEHHPGDALDPYALQ 5yu3 C 1.79 BS02 PRO C 1 E63 M65 K77 R121 E63 M65 K77 R121 4.3.1.12 0000166,0005737,0008473,0016829 D9UBW0 29629557 403 METWVLGRRDVAEVVAAVGRDELMRRIIDRLTGGLAEIGRGERHLSPLRGGLERSEPVPGIWEWMPHREPGDHITLKTVGYSPANPARFGLPTILGTVARYDDTTGALTALMDGVLLTALRTGAASAVASRLLARPDSHTLGLIGTGAQAVTQLHALSLVLPLQRALVWDTDPAHRESFARRAAFTGVSVEIAEPARIAAEADVISTATSVAVGQGPVLPDTGVREHLHINAVGADLVGKTELPLGLLERAFVTADHPEQALREGECQQLSADRLGPQLAHLCADPAAAAGRQDTLSVFDSTGFAFEDALAMEVFLEAAAERDLGIRVGIEHHPGDALDPYALQ 5yu3 D 1.79 BS02 PRO D 1 M65 K77 R121 M65 K77 R121 4.3.1.12 0000166,0005737,0008473,0016829 D9UBW0 29629557 403 METWVLGRRDVAEVVAAVGRDELMRRIIDRLTGGLAEIGRGERHLSPLRGGLERSEPVPGIWEWMPHREPGDHITLKTVGYSPANPARFGLPTILGTVARYDDTTGALTALMDGVLLTALRTGAASAVASRLLARPDSHTLGLIGTGAQAVTQLHALSLVLPLQRALVWDTDPAHRESFARRAAFTGVSVEIAEPARIAAEADVISTATSVAVGQGPVLPDTGVREHLHINAVGADLVGKTELPLGLLERAFVTADHPEQALREGECQQLSADRLGPQLAHLCADPAAAAGRQDTLSVFDSTGFAFEDALAMEVFLEAAAERDLGIRVGIEHHPGDALDPYALQ 5zs6 A 2.81191 BS02 PRO A 1 R124 K125 R106 K107 ? 0006457,0009408,0009651,0042542,0051082,0051259 B2HF11 30632633 204 LGTSARPAVMPMDAWREGDKFVVEFDLPGIDADSLDIDIERNVVTVRAERPAVDPNREMLASERPRGVFSRQLVLGENLDTARIAASYTEGVLKLQIPVAEKAKPRKISITR 5zw8 A 1.689 BS04 PRO A 1 I136 F237 H238 G366 I136 F237 H238 G366 A127 T128 E244 R377 A127 T128 E244 R377 1.3.8.14 0003995,0016491,0016627,0017000,0050660 Q5W271 30095206 506 MDFNLSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGFAHGPVSHQFGGSELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKYLESLVTGKLIAANAATEPDAGSDIYNMQATAQPCEGGYILNGKKIFITNAPIADVFIIYAKTNPDHGFLGVSAFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAIFHDSMIWEKGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQCRLMLYRACWKHDQGQDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELGLVRHLLNMIPSRIFSGTNDIQKEIIARKLGLRG 6af6 A 1.62 BS04 PRO A 1 M241 S365 M241 S365 A127 T128 A244 R377 A127 T128 A244 R377 1.3.8.14 0003995,0016491,0016627,0017000,0050660 Q5W271 30095206 505 MDFNLSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGFAHGPVSHQFGGSELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKYLESLVTGKLIAANAATEPDAGSDIYNMQATAQPCEGGYILNGKKIFITNAPIADVFIIYAKTNPDHGFLGVSAFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAIFHDSMIWAKGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQCRLMLYRACWKHDQGQDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELGLVRHLLNMIPSRIFSGTNDIQKEIIARKLGLRG 6af6 A 1.62 BS05 PRO A 2 G133 I136 F237 G133 I136 F237 A127 T128 A244 R377 A127 T128 A244 R377 1.3.8.14 0003995,0016491,0016627,0017000,0050660 Q5W271 30095206 506 MDFNLSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGFAHGPVSHQFGGSELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKYLESLVTGKLIAANAATEPDAGSDIYNMQATAQPCEGGYILNGKKIFITNAPIADVFIIYAKTNPDHGFLGVSAFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAIFHDSMIWAKGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQCRLMLYRACWKHDQGQDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELGLVRHLLNMIPSRIFSGTNDIQKEIIARKLGLRG 6b4e A 1.75 BS01 PRO A 1 I271 R279 L282 S283 W326 I29 R37 L40 S41 W84 ? 0005643,0016973 Q12315 29899397 603 MTNFDKISKMFWHYKDKIAQIKQDIVLPIKKADVNVRNLLSRHKRKINPKFGQLTNSNQQLFKIQNELTQLINDTKGDSLAYHWILNFIAKAVVHQAETEVRVKPESALPLGKLTLYLLVQFPELQELFMARLVKKCPFVIGFTCEIDTEKGRQNMGWKRNNENKWEDNTSYDERMGGILSLFAIITRLQLPQEFITTTSHPFPIALSWHILARICNTPLNLITNTHFVILGSWWDAAAVQFLQAYGNQASKLLILIGEELTSRMAEKKYVGAARLRILLEAWQNNNMESFPEMSP 6b4e D 1.75 BS01 PRO D 1 A402 E403 A3 E4 ? P49686 29899397 501 DLAEETLKIFRANKFELGLVPDIPPPPALVA 6bsn A 2.15 BS02 PRO A 1 F659 R791 S793 I945 G946 A947 F954 F644 R776 S778 I930 G931 A932 F939 N658 E758 A792 A966 N643 E743 A777 A951 1.2.1.88,1.5.5.2 0000166,0003677,0003700,0003842,0004657,0006355,0006560,0006561,0006562,0009898,0010133,0016491,0016620,0042802 Q89E26 29295473 2002 MPNIPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn A 2.15 BS03 PRO A 2 M645 A973 R974 A976 M630 A958 R959 A961 N658 E758 A792 A966 N643 E743 A777 A951 1.2.1.88,1.5.5.2 0000166,0003677,0003700,0003842,0004657,0006355,0006560,0006561,0006562,0009898,0010133,0016491,0016620,0042802 Q89E26 29295473 2003 MPNIPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn A 2.15 BS04 PRO A 3 W657 G733 F886 W642 G718 F871 N658 E758 A792 A966 N643 E743 A777 A951 1.2.1.88,1.5.5.2 0000166,0003677,0003700,0003842,0004657,0006355,0006560,0006561,0006562,0009898,0010133,0016491,0016620,0042802 Q89E26 29295473 2006 MPNIPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn B 2.15 BS02 PRO B 1 F659 S793 I945 G946 A947 F954 F644 S778 I930 G931 A932 F939 N658 E758 A792 A966 N643 E743 A777 A951 1.2.1.88,1.5.5.2 0000166,0003677,0003700,0003842,0004657,0006355,0006560,0006561,0006562,0009898,0010133,0016491,0016620,0042802 Q89E26 29295473 1002 IPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALRVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn B 2.15 BS03 PRO B 2 A973 R974 A976 E978 A958 R959 A961 E963 N658 E758 A792 A966 N643 E743 A777 A951 1.2.1.88,1.5.5.2 0000166,0003677,0003700,0003842,0004657,0006355,0006560,0006561,0006562,0009898,0010133,0016491,0016620,0042802 Q89E26 29295473 1003 IPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALRVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn B 2.15 BS04 PRO B 3 G733 F886 G718 F871 N658 E758 A792 A966 N643 E743 A777 A951 1.2.1.88,1.5.5.2 0000166,0003677,0003700,0003842,0004657,0006355,0006560,0006561,0006562,0009898,0010133,0016491,0016620,0042802 Q89E26 29295473 1005 IPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALRVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6d7j A 2.24 BS01 PRO A 1 L209 E210 S211 F305 G306 N418 P420 L188 E189 S190 F284 G285 N397 P399 ? 0004553,0005975 K5ZWV5 30230652 914 NAKVPAMNKIRLTNNWEYLKGDLGGIWEAVRPAAPGSSEAVPIWQPVTLPHCFNAEDAVDPDVNYYEGPGWYKTLLAIDNPYRNGRIVLDFDGAGQKTDVYVYTTHVGSHVGGYDSWNVDITDAVKAFLGSKDAERFKGKVPLSIRCDNSRDLEMIPSDLADFNIYGGLYRYLNLVYLPEVSFEQIHLESSLSSNLKEGILKVKTSFYNPEDIRKADVTVSVYDVDRKPVFSKTLEGILPLGDQLLAKMKIKNPVLWDVDVPQLYTCELTVKTPDQTFTTEERFGFRHTEFKDKGPFFLNGKRLLLRGTHRHEDHAGVAQAMTEDMMRREMRMMKDMGVNFIRLGHYQQSEIILDLCDELGILVWEEIPWCRGGLGGDVYKKQARRMLANMIVQHHNHPAVIIWGLGNENDWPNDFNTFDKSAIRAFMKELHDMAHRLDDTRMTAIRRCEFCNDIVDVYSPSIWAGWYRGVFTDYKSISEQEMQKVKHFLHVEWGGDSHARRHSEDAFYNLKNIEGDASLYGGVPRASRDGDWSESYVVRLIDWHLKEQETMPWLTGTAYWPFKDFSTPVRPDNPVPYVNQKGVVERDFTPKESYYVFQSYWTEKPMIHIYGHTWPVRWGGKDDRKEILVYSNCDEVELFVNGVSQGVKRRNSQDYPAAGLRWNCVYQEGMNEIRAVGVKKKEKKEVSDVIRQEYQTAKWDKEAACQVSLLSEEGDTALVQVQLIDKNGIRCLSSKKQITFEIAGDGSLICNLGTSTGSRKVQAYNGRALIRIKRNEGNSVVAVKSEGLPTAFLELKSP 6d7j D 2.24 BS01 PRO D 1 E501 W584 E481 W543 ? 0004553,0005975 K5ZWV5 30230652 910 SNAKVPAMNKIRLTNNWEYLKGDLGGIWEAVRPAAPGSSEAVPIWQPVTLPHCFNAEDAVDPDVNYYEGPGWYKTLLAIDNPYRNGRIVLDFDGAGQKTDVYVYTTHVGSHVGGYDSWNVDITDAVKAFLGSKDAERFKGKVPLSIRCDNSRDLEMIPSDLADFNIYGGLYRYLNLVYLPEVSFEQIHLESSLSSNLKEGILKVKTSFYNPEDIRKADVTVSVYDVDRKPVFSKTLEGILPLGDQLLAKMKIKNPVLWDVDVPQLYTCELTVKTPDQTFTTEERFGFRHTEFKDKGPFFLNGKRLLLRGTHRHEDHAGVAQAMTEDMMRREMRMMKDMGVNFIRLGHYQQSEIILDLCDELGILVWEEIPWCRGGLGGDVYKKQARRMLANMIVQHHNHPAVIIWGLGNENDWPNDFNTFDKSAIRAFMKELHDMAHRLDDTRMTAIRRCEFCNDIVDVYSPSIWAGWYRGVFTDYKSISEQEMQKVKHFLHVEWGGDSHARRHSEDAFYNLKPRASRDGDWSESYVVRLIDWHLKEQETMPWLTGTAYWPFKDFSTPVRPDNPVPYVNQKGVVERDFTPKESYYVFQSYWTEKPMIHIYGHTWPVRWGGKDDRKEILVYSNCDEVELFVNGVSQGVKRRNSQDYPAAGLRWNCVYQEGMNEIRAVGVKKKEKKEVSDVIRQEYQTAKWDKEAACQVSLLSEEGDTALVQVQLIDKNGIRCLSSKKQITFEIAGDGSLICNLGTSTGSRKVQAYNGRALIRIKRNEGNSVVAVKSEGLPTAFLELKS 6dvo A 1.98 BS02 PRO A 1 E515 T540 E73 T98 ? F8W4B7 30118224 804 ITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLPLKTSATVSINNVLRAHAPFWSSLR 6ehj A 2.1 BS05 PRO A 1 H298 F311 H181 F194 2.3.1.-,2.3.1.97 0004379,0006499 P30419 32111831 510 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 6ehj B 2.1 BS06 PRO B 1 F311 I469 F197 I349 2.3.1.-,2.3.1.97 0004379,0006499 P30419 32111831 511 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 6emf B 2.65 BS01 PRO B 1 Q68 N72 R118 Q63 N67 R113 ? 0005634,0006364,0030688 G0S4M2 29245012 301 KSMPFIKHLASSDRKVRTAALNSLHAFLSARQVASALTTLDVLKLWKGLFYALWMCDRAIPQQNLCNELADLIWQLPRESVATWLRGFWATMAREWTGIDVLRMEKFLLLVRRVLGASFKWMKKDGSTGAWDQSKVDEVLGLLAEWPFSLAEEVRITGEIVQKIPVGMRLHVLDIWVDEVERVGLLNEDEEEARMIVQRISDMVDALEQTTKSPAVRTRSKDSLGDDRLPANR 6emf B 2.65 BS02 PRO B 2 K49 R99 K44 R94 ? 0005634,0006364,0030688 G0S4M2 29245012 302 KSMPFIKHLASSDRKVRTAALNSLHAFLSARQVASALTTLDVLKLWKGLFYALWMCDRAIPQQNLCNELADLIWQLPRESVATWLRGFWATMAREWTGIDVLRMEKFLLLVRRVLGASFKWMKKDGSTGAWDQSKVDEVLGLLAEWPFSLAEEVRITGEIVQKIPVGMRLHVLDIWVDEVERVGLLNEDEEEARMIVQRISDMVDALEQTTKSPAVRTRSKDSLGDDRLPANR 6h2q A 1.78 BS04 PRO A 1 H255 H366 R398 E412 H250 H361 R393 E407 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 507 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECQVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCFTP 6h2q B 1.78 BS04 PRO B 1 H255 H366 H377 R398 E412 H250 H361 H372 R393 E407 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 30066404 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECQVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCD 6ios A 2.35 BS01 PRO A 1 W114 Y120 R125 W127 D145 F170 D172 W85 Y91 R96 W98 D116 F141 D143 ? Kd=23.8uM -logKd/Ki=4.10, Kd=79.4uM Q9KQ43 30745373 501 VREEIESLVQDSLMEMVKGVKNTIESDLASKKGLAQSTTEILQLDPTNKAFAKSVLESPNLKGSFLAIGLGYESDATVVENDDGWEPNADYDPRKRPWYVDAKRERKLVVTEPYVDISTKKIIISIGTPVYQQSNFVGAMFYDVELTQLAQLVNSVNLFDAGYLFITTKDGVTIAHPNAENNGEKFSQFLPNVDLKEGTQRIELDGKYYLVKFAQVPSESWYIGAVVDESIAFAMVD 6j7c A 2.7 BS01 PRO A 1 C88 G89 H90 W241 D247 C251 G252 T253 C88 G89 H90 W241 D247 C251 G252 T253 ? 0047580 H3ZMH5 30773259 401 LFADHVFHVVDTHTEGEPTRIVLSGVNVKGEDIIEKREYFKEHYDWIRTALLHEPRGHSDQFGAVLVPSDIADFGVIYMDTSGYLDMCGHATMGVATVLVELGIIEKKEPYTTVKLETPAGLVEAKAKVKGGVVKEVTVVDVPSFYVGEFVIEYPGRGKIKVDVAFGGNFYVIADARDLGLRVRREYIKELIPTALKLIKVANEQIKVQHPRKGVQNRINLAMLTDEPEREDSDGKNVVIWGEGSVDRSPCGTGSASRVATLYSKGILKEGDIFVHESILGTQFRIKIVGTTKIGEYTAIIPEITGSAYITKISQDIISKNDPLWKGFLLR 6mni A 1.696 BS01 PRO A 1 Y114 Y124 Y136 R141 W143 Y160 W162 D190 Y86 Y96 Y108 R113 W115 Y132 W134 D162 33721671 301 NLRDKATSDFVDSSGREIRQVDNAMQLFFDGITQNVNYIAAHPLIAGAGDDFRNYMGAVATAQSENDKQATELFASIAKAHPAYSYVSYGLINGSYIMTPEDPKMSNYDPRVRPWYKTAMANAGKTVRSDAYYWANDDAVLVSTIRAIPNKLGNPGGVVNIDVSLKQLTNIVKQIKLGESGYLMLMEKNGTVLVDPKQPEHNFKKLGELGDGFAELAKTGSGLVELTLNGERYMANVYPSEQLGWNFIGLIKQDEVMA 6mni B 1.696 BS01 PRO B 1 Y114 Y124 Y136 R141 W143 Y160 W162 L169 D190 Y80 Y90 Y102 R107 W109 Y126 W128 L135 D156 33721671 301 TSDFVDSSGREIRQVDNAMQLFFDGITQNVNYIAAHPLIAGAGDDFRNYMGAVATAQSENDKQATELFASIAKAHPAYSYVSYGLINGSYIMTPEDPKMSNYDPRVRPWYKTAMANAGKTVRSDAYYWANDDAVLVSTIRAIPNKLGNPGGVVNIDVSLKQLTNIVKQIKLGESGYLMLMEKNGTVLVDPKQPEHNFKKLGELGDGFAELAKTGSGLVELTLNGERYMANVYPSEQLGWNFIGLIKQDEVM 6nab A 2.0 BS02 PRO A 1 T111 E113 W159 E161 F206 H232 S260 W261 G262 T108 E110 W156 E158 F203 H229 S257 W258 G259 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433,0017101 A0A4V8H034 602 EGIDVKKQENFSEWYSQVITKSEFLDYYDVSGCYIFRPNCWFVWESVQKFFDAEIKKLGVQNVMFPLFVTKRALETEKDHVEGFSPEVAWVTKSGNSDLQEPIALRPTSETIMYPSYAKWIQSHRDLPLKLNQWTNVVRWEFKHAVPFIRSREFYWQEGHSAFKSKEEADEEVFTILELYKRVYEELLAVPVIKGTKTENEKFAGADYTTTVETFIATNGRAVQGGTSHHLGQNFSKMFKIQFEAENKETQFAYQNSWGLSTRTLGVMIMVHGDDKGMVLPPRVAFCQVVVIPLIDNATLVEKTKEIYNELEKAGIRVKLDDRRTPGWKYNYWELRGVPLRIEVGPKDLEKQQIMLCRRDTGEKWTMPLSEFSGDSIKAVLDKIHDSMLNKARKEMNERIVVTRTWPEFIKALNSGNMCLIPWHESKAAEEYIKEKSKLESVQSQSDANTGLTGAAKSLCVPLDQSSFPSLEGLENFYPEEAHKKPNCWALFGRSY 6nab B 2.0 BS02 PRO B 1 T111 E113 W159 E161 F206 H232 W261 G262 T108 E110 W156 E158 F203 H229 W258 G259 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433,0017101 A0A4V8H034 602 EGIDVKKQENFSEWYSQVITKSEFLDYYDVSGCYIFRPNCWFVWESVQKFFDAEIKKLGVQNVMFPLFVTKRALETEKDHVEGFSPEVAWVTKSGNSDLQEPIALRPTSETIMYPSYAKWIQSHRDLPLKLNQWTNVVRWEFKHAVPFIRSREFYWQEGHSAFKSKEEADEEVFTILELYKRVYEELLAVPVIKGTKTENEKFAGADYTTTVETFIATNGRAVQGGTSHHLGQNFSKMFKIQFEAENKETQFAYQNSWGLSTRTLGVMIMVHGDDKGMVLPPRVAFCQVVVIPLINATLVEKTKEIYNELEKAGIRVKLDDRLERTPGWKYNYWELRGVPLRIEVGPKDLEKQQIMLCRRDTGEKWTMPLSEFSGDSIKAVLDKIHDSMLNKARKEMNERIVVTRTWPEFIKALNSGNMCLIPWHESKAAEEYIKEKSKLESVQSQSDANTGLTGAAKSLCVPLDQSSFPSLEGLENFYPEEAHKKPNCWALFGRSY 6nag A 2.683 BS01 PRO A 1 L197 K198 L155 K156 ? Q8A9T8 30835452 402 VPTEQTVFMYLPWSDNLTSNFYQNISDLESVVEKNILKDERIIIFMCTTATKATLFELAYENGKSVHKTLKNYTDPAYTTAEGITSILNDVQRYSPTKRYSMVIGCHGMGWIPVSNSKSAWEYENVPMTRYFGGLNAQYQTDITTLAKGISNAGLKMEYILFDDCYMSSIEVAYALKDVTDYLIGSTSEVMAYGMPYAEIGQYLIGKVDYAGICDGFYSFYSTYSTPCGTIAVTDCSELDNLATIMKEINHRYTFDPSLTSSLQRLDGYYPVIFFDYGDYVSKLCPDETLVARFNEQLNRTVPFKRNTEYFYSMSRGEVKINTFSGITISDPSTHSLASKKEETAWYAATH 6nag A 2.683 BS02 PRO A 2 P110 A111 G117 S120 P76 A77 G83 S86 ? Q8A9T8 30835452 403 VPTEQTVFMYLPWSDNLTSNFYQNISDLESVVEKNILKDERIIIFMCTTATKATLFELAYENGKSVHKTLKNYTDPAYTTAEGITSILNDVQRYSPTKRYSMVIGCHGMGWIPVSNSKSAWEYENVPMTRYFGGLNAQYQTDITTLAKGISNAGLKMEYILFDDCYMSSIEVAYALKDVTDYLIGSTSEVMAYGMPYAEIGQYLIGKVDYAGICDGFYSFYSTYSTPCGTIAVTDCSELDNLATIMKEINHRYTFDPSLTSSLQRLDGYYPVIFFDYGDYVSKLCPDETLVARFNEQLNRTVPFKRNTEYFYSMSRGEVKINTFSGITISDPSTHSLASKKEETAWYAATH 6q0g A 2.0 BS01 PRO A 1 Y101 F109 I111 R126 W128 Y144 D146 A147 D173 Y63 F71 I73 R88 W90 Y106 D108 A109 D135 ? Q3K7T6 31909676 301 REDLDNYLNEMGEVTADNIQTWLSGRILLIENAAQNIAINPEPAAVASLLEQKALTSTFMASYLGDATGHFTIRPDAKMPDGFDPRVRPWYKGAESSSTSTLTEPYIDAATGQTIISIATAAKKAGQSVGVVGGDLSLQTLINTLSARDGMGYAFLVSADGKILVHPDKALVMKSLKEAYPQDTPRISSDFSERIVNFTPIKGLPSVNWYIGLSVDKDKAF 6qsc A 1.569 BS03 PRO A 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 33877262 507 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPHTVEEIEACMAGC 6qsc B 1.569 BS03 PRO B 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 33877262 510 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPHTVEEIEACMAGCDKAFTP 6rng B 2.15 BS02 PRO B 1 G267 R298 G262 R293 D30 K142 E183 E185 K225 S295 D25 K137 E178 E180 K220 S290 4.1.2.13 0003729,0004332,0005507,0005515,0005634,0005737,0005739,0005783,0005829,0005886,0006094,0006096,0009506,0016829,0031930,0071456,1901149 Q9SJQ9 408 SKFADELIANAAYIGTPGKGILAADESTGTIGKRLASINVENVESNRRALRELLFTTPGALPCLSGVILFEETLYQKSSDGTPFVDMLKSAGVLPGIKVDKGTVELAGTNGETTTQGLDGLGDRCKKYYEAGARFAKWRAVLKIGVNEPSQLAIHENAYGLARYAVICQENGLVPIVEPEILVDGSHDIQKCAAVTERVLAACYKALSDHHVLLEGTLLKPNMVTPGSESAKVAPEVIAEHTVRALQRTVPAAVPAIVFLSGGQSEEEATRNLNAMNQLKTKKPWSLSFSFGRALQQSTLKTWGGKEENVKKAQEAFLVRCKANSEATLGAYKG 6rng G 2.15 BS02 PRO G 1 R39 K225 R34 K220 D30 K142 E183 E185 K225 S295 D25 K137 E178 E180 K220 S290 4.1.2.13 0003729,0004332,0005507,0005515,0005634,0005737,0005739,0005783,0005829,0005886,0006094,0006096,0009506,0016829,0031930,0071456,1901149 Q9SJQ9 406 SKFADELIANAAYIGTPGKGILAADESTGTIGKRLASINVENVESNRRALRELLFTTPGALPCLSGVILFEETLYQKSSDGTPFVDMLKSAGVLPGIKVDKGTVELAGTNGETTTQGLDGLGDRCKKYYEAGARFAKWRAVLKIGVNEPSQLAIHENAYGLARYAVICQENGLVPIVEPEILVDGSHDIQKCAAVTERVLAACYKALSDHHVLLEGTLLKPNMVTPGSESAKVAPEVIAEHTVRALQRTVPAAVPAIVFLSGGQSEEEATRNLNAMNQLKTKKPWSLSFSFGRALQQSTLKTWGGKEENVKKAQEAFLVRCKANSEATLGAYKG 6sre A 1.39 BS03 PRO A 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 32598484 508 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKIFSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 6sre B 1.39 BS03 PRO B 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 32598484 509 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKIFSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTP 6srf A 1.847 BS03 PRO A 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 32598484 505 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMDGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDFTPF 6srf B 1.847 BS03 PRO B 1 H255 H366 H377 R398 E412 R450 H250 H361 H372 R393 E407 R445 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 32598484 504 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMDGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDK 6srg A 2.558 BS04 PRO A 1 H366 H377 R398 E412 H338 H349 R370 E384 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 32598484 505 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGRVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCD 6srg B 2.558 BS04 PRO B 1 H366 H377 R398 H346 H357 R378 3.4.13.9 0004181,0005515,0006508,0006520,0008233,0008237,0016805,0030145,0030574,0043069,0046872,0070006,0070062,0102009 P12955 32598484 505 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGRVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTP 6t3e A 2.6 BS01 PRO A 1 K71 V73 R114 W227 V301 K67 V69 R110 W223 V297 1.5.1.21 0000166,0000286,0005737,0006522,0051287 H3ZMH3 32355045 401 MLLLSRSDLEKLISMKEVIESVERAFLELYNGKAKVPLRTIIEVEKHNGFILYMPSYLEDSEALAVKVVSLYPENTKKGLPSVLASILLNDPKTGAPLALMEGTFITAMRTGAASGVATKYLARKDSKIAGIIGAGVQARTQLWAVCEVRNIEKALVYDINPKNAKKFAEEMSKKLGIEIKTVESAREATEKSDILIVATTAREPVVKGGWIREGTHINSVGWVGRDARELDSETVRKSKLVVDSKEGVLNESGDIIIPMKEGVIDEGHIHAELAEIVAGVKKGRENNREITLFKSVGLAIEDAITAKLAYEKALEHGVGTNV 6t3e B 2.6 BS01 PRO B 1 R43 M58 K71 R114 R39 M54 K67 R110 1.5.1.21 0000166,0000286,0005737,0006522,0051287 H3ZMH3 32355045 401 MLLLSRSDLEKLISMKEVIESVERAFLELYNGKAKVPLRTIIEVEKHNGFILYMPSYLEDSEALAVKVVSLYPENTKKGLPSVLASILLNDPKTGAPLALMEGTFITAMRTGAASGVATKYLARKDSKIAGIIGAGVQARTQLWAVCEVRNIEKALVYDINPKNAKKFAEEMSKKLGIEIKTVESAREATEKSDILIVATTAREPVVKGGWIREGTHINSVGWVGRDARELDSETVRKSKLVVDSKEGVLNESGDIIIPMKEGVIDEGHIHAELAEIVAGVKKGRENNREITLFKSVGLAIEDAITAKLAYEKALEHGVGTNVEL 6t7k A 1.79 BS01 PRO A 1 T359 E361 W407 E409 H411 F454 H480 S508 W509 G510 T110 E112 W158 E160 H162 F205 H231 S259 W260 G261 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 Q8I5R7 801 NILGITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKEKNHIEGFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLTNSETTLSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 6x9c A 1.44 BS03 PRO A 1 R843 C844 S845 G1002 A1003 F1010 R823 C824 S825 G982 A983 F990 N707 K730 E810 C844 E940 A1022 N687 K710 E790 C824 E920 A1002 1.2.1.88,1.5.5.2 0000166,0003677,0003700,0003842,0004657,0006355,0006560,0006561,0006562,0009898,0010133,0016491,0016620 Ki=11mM F7X6I3 33333077 1309 PAPFADFAPPVRPQSTLRRAITAAYRRPETECLPPLVEAATQSKEIRDAAASTARKLIEALRGKSGVEGLVQEYSLSSQEGVALMCLAEALLRIPDTATRDALIRDKIADGNWKSHLRSLFVNAATWGLVVTGKLTSTVNDRSLAAALTRLISRCGEPVIRRGVDMAMRMMGEQFVTGETIREALKRSKELEEKGFSYSYDMLGEAATTAADAERYYRDYESAIHAIGKASAGRGIYEGPGISIKLSALHPRYSRAQAARVMGELLPRVKALALLAKNYDIGLNIDAEEADRLELSLDLLEVLCLDGDLSGWNGMGFVVQAYGKRCPFVLDFIIDLARRSGRRIMVRLVKGAYWDAEIKRAQLDGLADFPVFTRKIHTDVSYIACAAKLLAATDVVFPQFATHNAQTLAAIYHMAGKDFHVGKYEFQCLHGMGEPLYEEVVGRGKLDRPCRIYAPVGTHETLLAYLVRRLLENGANSSFVHRINDPKVSIDELIADPVEVVRAMPVVGAKHDRIALPAELFGDARTNSAGLDLSNEETLASLTEALRESAAMKWTALPQLATGPAAGETRTVLNPGDHRDVVGSVTETSEEDARRAVRLAADAAPDWAAVPPSERAACLDRAAELMQARMPTLLGLIIREAGKSALNAIAEVREAIDFLRYYAEQTRRTLGPGHGPLGPIVCISPWNFPLAIFTGQIAAALVAGNPVLAKPAEETPLIAAEGVRILREAGIPASALQLLPGDGRVGAALVAAAETAGVMFTGSTEVARLIQAQLADRLSPAGRPIPLIAETGGQNAMIVDSSALAEQVVGDVITSAFDSAGQRCSALRVLCLQEDVADRILTMLKGALHELHIGRTDRLSVDVGPVITSEAKDNIEKHIERMRGLGRKVEQIGLASETGVGTFVPPTIIELEKLSDLQREVFGPVLHVIRYRRDDLDRLVDDVNATGYGLTFGLHTRLDETIAHVTSRIKAGNLYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVTTAPVPPQHSSVHTDPVLLDFAKWLDGKGARAEAEAARNAGSSSALGLDLELPGPVGERNLYTLHARGRILLVPATESGLYHQLAAALATGNSVAIDAASGLQASLKNLPQTVGLRVSWSKDWAADGPFAGALVEGDAERIRAVNKAIAALPGPLLLVQAASSGEIARNPDAYCLNWLVEEVSASINTAAAGGNASL 6x9c B 1.44 BS03 PRO B 1 E674 F708 C844 S845 G1002 A1003 F1010 E653 F687 C823 S824 G981 A982 F989 N707 K730 E810 C844 E940 A1022 N686 K709 E789 C823 E919 A1001 1.2.1.88,1.5.5.2 0000166,0003677,0003700,0003842,0004657,0006355,0006560,0006561,0006562,0009898,0010133,0016491,0016620 Ki=11mM F7X6I3 33333077 1307 PAPFADFAPPVRPQSTLRRAITAAYRRPETECLPPLVEAATQSKEIRDAAASTARKLIEALRGKSGVEGLVQEYSLSSQEGVALMCLAEALLRIPDTATRDALIRDKIADGNWKSHLRSLFVNAATWGLVVTGKLTSTVNDRSLAAALTRLISRCGEPVIRRGVDMAMRMMGEQFVTGETIREALKRSKELEEKGFSYSYDMLEAATTAADAERYYRDYESAIHAIGKASAGRGIYEGPGISIKLSALHPRYSRAQAARVMGELLPRVKALALLAKNYDIGLNIDAEEADRLELSLDLLEVLCLDGDLSGWNGMGFVVQAYGKRCPFVLDFIIDLARRSGRRIMVRLVKGAYWDAEIKRAQLDGLADFPVFTRKIHTDVSYIACAAKLLAATDVVFPQFATHNAQTLAAIYHMAGKDFHVGKYEFQCLHGMGEPLYEEVVGRGKLDRPCRIYAPVGTHETLLAYLVRRLLENGANSSFVHRINDPKVSIDELIADPVEVVRAMPVVGAKHDRIALPAELFGDARTNSAGLDLSNEETLASLTEALRESAAMKWTALPQLATGPAAGETRTVLNPGDHRDVVGSVTETSEEDARRAVRLAADAAPDWAAVPPSERAACLDRAAELMQARMPTLLGLIIREAGKSALNAIAEVREAIDFLRYYAEQTRRTLGPGHGPLGPIVCISPWNFPLAIFTGQIAAALVAGNPVLAKPAEETPLIAAEGVRILREAGIPASALQLLPGDGRVGAALVAAAETAGVMFTGSTEVARLIQAQLADRLSPAGRPIPLIAETGGQNAMIVDSSALAEQVVGDVITSAFDSAGQRCSALRVLCLQEDVADRILTMLKGALHELHIGRTDRLSVDVGPVITSEAKDNIEKHIERMRGLGRKVEQIGLASETGVGTFVPPTIIELEKLSDLQREVFGPVLHVIRYRRDDLDRLVDDVNATGYGLTFGLHTRLDETIAHVTSRIKAGNLYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVTTAPVPPQHSSVHTDPVLLDFAKWLDGKGARAEAEAARNAGSSSALGLDLELPGPVGERNLYTLHARGRILLVPATESGLYHQLAAALATGNSVAIDAASGLQASLKNLPQTVGLRVSWSKDWAADGPFAGALVEGDAERIRAVNKAIAALPGPLLLVQAASSGEIARNPDAYCLNWLVEEVSASINTAAAGGNASL 6yb6 H 1.33 BS04 PRO D 1 H57 Y60A W60D L99 H43 Y47 W50 L96 H57 D102 E192 G193 D194 S195 G196 H43 D99 E195 G196 D197 S198 G199 3.4.21.5 0004252,0005509,0006508,0007596 P00734 101 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 6ywt A 1.05 BS02 PRO A 1 Q420 A423 G424 G425 Y432 Q197 A200 G201 G202 Y209 2.4.2.10,4.1.1.23 0004590,0006207,0044205 P11172 503 ELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLG 6zm9 A 1.45 BS01 PRO A 1 N20 G22 Y58 E69 Q104 N20 G22 Y58 E69 Q104 33567250 204 SLMERLGGGGFSARIFVGLNVGDKPTYTIEDVVKDTIAIRKRQGILPDASFVAQRGVYTEQRSGQLVTENSVQIIIIDLEGLSKEDFTGKVQALGKELREDFKQESVIVEIQERGIVQDVYSITAEWYE 6zx1 A 1.0 BS02 PRO A 1 G228 A229 E232 G5 A6 E9 2.4.2.10,4.1.1.23 0004590,0006207,0044205 P11172 502 ELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLG 6zx1 A 1.0 BS03 PRO A 2 Q420 A423 G424 G425 Y432 Q197 A200 G201 G202 Y209 2.4.2.10,4.1.1.23 0004590,0006207,0044205 P11172 503 ELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLG 6zx2 A 1.2 BS02 PRO A 1 G228 A229 E232 G5 A6 E9 2.4.2.10,4.1.1.23 0004590,0006207,0044205 P11172 502 ELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLG 6zx3 A 1.15 BS02 PRO A 1 G228 A229 E232 G5 A6 E9 2.4.2.10,4.1.1.23 0004590,0006207,0044205 P11172 503 ELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLG 7bbu A 2.19 BS01 PRO A 1 T1121 E1123 W1169 E1171 H1173 F1216 H1242 W1273 G1274 T103 E105 W151 E153 H155 F198 H224 W255 G256 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 1801 TRLGLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARSMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7bem E 2.52 BS01 PRO E 1 T376 G404 Y508 T43 G71 Y175 ? P0DTC2 33756110 802 NLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLH 7bem E 2.52 BS02 PRO E 2 R346 N354 R13 N21 ? P0DTC2 33756110 805 NLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLH 7dt0 A 2.43 BS03 PRO A 1 F119 W120 R246 F110 W111 R233 ? 0046872,0051213 S5TUM1 503 TLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVEQNTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKIIAKRAFWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADGWANTLTASLKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7dt0 B 2.43 BS02 PRO B 1 W120 R246 W114 R224 ? 0046872,0051213 S5TUM1 502 TLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVEQNTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKIIAKRAFKGEWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMILKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7dt0 D 2.43 BS03 PRO D 1 W120 R246 W110 R223 ? 0046872,0051213 S5TUM1 503 TLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKIIAKRAFKGWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADLKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7dt0 E 2.43 BS03 PRO E 1 F119 W120 R246 F113 W114 R226 ? 0046872,0051213 S5TUM1 503 TLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVEQNTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKIIAKRAFKGEWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7dt0 F 2.43 BS03 PRO F 1 Q97 F119 W120 R246 Q92 F112 W113 R225 ? 0046872,0051213 S5TUM1 503 TLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVEQNTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKIIAKRAFKGWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7dt0 G 2.43 BS03 PRO G 1 Q97 F119 W120 R246 Q92 F113 W114 R227 ? 0046872,0051213 S5TUM1 503 TLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVEQNTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKIIAKRAFKGEWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADLKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQA 7dt0 H 2.43 BS03 PRO H 1 D116 W120 R246 D110 W114 R221 ? 0046872,0051213 S5TUM1 503 TLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVEQNTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKIIAKRAFKEVWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGIGKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7dzz A 1.95 BS01 PRO A 1 Q97 H114 D116 F119 W120 T172 R246 Q93 H110 D112 F115 W116 T168 R242 ? 0046872,0051213 S5TUM1 301 QIMEPHDTLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKINAKRAFKGEVWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADVKGEGWANTLTASLKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7dzz B 1.95 BS01 PRO B 1 Q97 H114 D116 F119 W120 T172 R246 Q99 H116 D118 F121 W122 T174 R248 ? 0046872,0051213 S5TUM1 301 QIMEPHDTLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVEQNTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKINAKRAFKGEVWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADVKGEGWANTLTASLKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7e00 A 1.92 BS01 PRO A 1 Q97 H114 D116 W120 T172 R246 Q96 H110 D112 W116 T168 R242 ? 0046872,0051213 S5TUM1 601 QIMEPHDTLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKINAKRAFVWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADVKGEGWANTLTASLKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7e00 B 1.92 BS01 PRO B 1 Q97 H114 D116 F119 W120 T172 R246 Q99 H116 D118 F121 W122 T174 R248 ? 0046872,0051213 S5TUM1 701 QIMEPHDTLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVEQNTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKINAKRAFKGEVWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADVKGEGWANTLTASLKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7e01 A 1.72 BS01 PRO A 1 Q97 H114 D116 W120 T172 R246 Q95 H112 D114 W118 T170 R244 ? 0046872,0051213 S5TUM1 301 MEPHDTLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVETGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKINAKRAFKGEVWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADVKGEGWANTLTASLKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7e07 A 2.14 BS02 PRO A 1 Q97 D116 F119 W120 T172 R246 Q98 D117 F120 W121 T173 R247 ? 0046872,0051213 S5TUM1 502 QIMEPHDTLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVENTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKINAKRAFKGEVWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADVKGEGWANTLTASLKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7e07 B 2.14 BS03 PRO B 1 Q97 D116 F119 W120 T172 R246 Q99 D118 F121 W122 T174 R248 ? 0046872,0051213 S5TUM1 303 QIMEPHDTLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVEQNTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKINAKRAFKGEVWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADVKGEGWANTLTASLKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 7evv A 1.704 BS02 PRO A 1 T439 E441 W487 E489 F534 H560 S588 W589 G590 T100 E102 W148 E150 F195 H221 S249 W250 G251 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 35333915 902 GAMVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEAGDQVMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7f96 A 2.577 BS02 PRO A 1 T359 E361 W407 F454 H480 W509 T105 E107 W153 F200 H226 W255 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 Q8I5R7 902 GAMAITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKEKFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLNTTLSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 7f97 A 2.394 BS01 PRO A 1 T359 E361 W407 E409 F454 H480 S508 W509 G510 T108 E110 W156 E158 F203 H229 S257 W258 G259 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 Q8I5R7 801 MAITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKEKNHIEGFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLLSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 7f97 B 2.394 BS01 PRO B 1 T359 E361 W407 E409 H480 W509 G510 T99 E101 W147 E149 H220 W249 G250 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 Q8I5R7 801 MAITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLESPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLNQTLSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 7f97 C 2.394 BS01 PRO C 1 T359 E361 W407 E409 F454 H480 S508 W509 G510 T101 E103 W149 E151 F196 H222 S250 W251 G252 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 Q8I5R7 801 MAITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 7f97 D 2.394 BS01 PRO D 1 T359 E361 W407 E409 F454 H480 S508 W509 G510 T101 E103 W149 E151 F196 H222 S250 W251 G252 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 Q8I5R7 801 MAITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKEKNEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKNAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 7f98 A 1.999 BS05 PRO A 1 T1121 E1123 W1169 E1171 F1216 H1242 W1273 G1274 T107 E109 W155 E157 F202 H228 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1909 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f98 B 1.999 BS05 PRO B 1 T1121 E1123 W1169 E1171 F1216 H1242 S1272 W1273 G1274 T107 E109 W155 E157 F202 H228 S258 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1907 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTASMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f99 A 1.979 BS05 PRO A 1 T1121 E1123 W1169 E1171 H1173 F1216 H1242 S1272 W1273 G1274 T106 E108 W154 E156 H158 F201 H227 S257 W258 G259 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1909 LEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGILSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTASMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f99 B 1.979 BS04 PRO B 1 T1121 E1123 W1169 E1171 H1173 F1216 H1242 S1272 W1273 G1274 T107 E109 W155 E157 H159 F202 H228 S258 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1904 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f9a A 1.999 BS05 PRO A 1 T1121 E1123 W1169 E1171 F1216 H1242 W1273 G1274 T108 E110 W156 E158 F203 H229 W260 G261 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1913 LGLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f9a B 1.999 BS05 PRO B 1 T1121 E1123 W1169 E1171 F1216 H1242 S1272 W1273 G1274 T108 E110 W156 E158 F203 H229 S259 W260 G261 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1906 LGLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTAMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f9b A 1.995 BS04 PRO A 1 T1121 E1123 W1169 E1171 F1216 H1242 S1272 W1273 G1274 T107 E109 W155 E157 F202 H228 S258 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1907 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTAMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f9b B 1.995 BS04 PRO B 1 T1121 E1123 W1169 E1171 H1173 F1216 H1242 W1273 T107 E109 W155 E157 H159 F202 H228 W259 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1907 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f9c A 2.196 BS05 PRO A 1 T1121 E1123 W1169 E1171 H1173 F1216 H1242 W1273 G1274 T106 E108 W154 E156 H158 F201 H227 W258 G259 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1908 LEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTAPSMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f9c B 2.196 BS04 PRO B 1 T1121 E1123 W1169 E1171 F1216 H1242 S1272 W1273 G1274 T107 E109 W155 E157 F202 H228 S258 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1908 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGISEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDSMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f9d A 2.497 BS06 PRO A 1 T1121 E1123 W1169 E1171 H1173 F1216 H1242 S1272 W1273 G1274 T107 E109 W155 E157 H159 F202 H228 S258 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1909 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f9d B 2.497 BS04 PRO B 1 T1121 E1123 W1169 E1171 F1216 H1242 S1272 W1273 G1274 T107 E109 W155 E157 F202 H228 S258 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 36854028 1606 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTAMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7f9r A 1.83 BS03 PRO A 1 T439 E441 W487 E489 H560 W589 G590 T98 E100 W146 E148 H219 W248 G249 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 912 AMVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEAGDVMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7fak A 1.899 BS02 PRO A 1 T439 E441 W487 E489 H491 F534 H560 W589 G590 T100 E102 W148 E150 H152 F195 H221 W250 G251 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 36854028 902 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKEKPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEAGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7fal A 3.219 BS02 PRO A 1 T439 E441 R470 W487 F534 H560 S588 W589 T101 E103 R132 W149 F196 H222 S250 W251 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 36854028 902 GAMVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKEPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEAGDGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7fal B 3.219 BS02 PRO B 1 T439 E441 R470 W487 F534 H560 W589 T101 E103 R132 W149 F196 H222 W251 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 36854028 902 GAMVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKEPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIVMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7fam A 2.42 BS02 PRO A 1 T439 E441 W487 E489 F534 H560 S588 W589 G590 T97 E99 W145 E147 F192 H218 S246 W247 G248 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A125YZ49 36854028 902 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEAGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7fan A 1.769 BS02 PRO A 1 T439 E441 W487 E489 H560 S588 W589 G590 T100 E102 W148 E150 H221 S249 W250 G251 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A125YZ49 36854028 902 GAMVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEAGMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7k5n A 1.8 BS01 PRO A 1 Y119 R144 W146 Y163 D165 Y166 D193 Y76 R101 W103 Y120 D122 Y123 D150 2.7.7.65 A0A3S5WQC2 34233153 301 ERSLQRELQQRLLATNHQLRHVFIEPYLNEMERQFSLIYDQIKVEDISGPRLRNTDSYLREWRLYKGVMADLIYIYVGTAERQMLIYPEWQADADFDPRVRPWYQLASQHVGKMVWTEPYYDYTNGTLVIALARAITDKEGKVRGVFAVDAILAPFSAQLNRQWNSGYQMIVNQSGKVLAHPDPSQLLKPMTHPTWLSRFSGEDGIFLDQASRQFVAYSRLPDHNWVLISVLPASSI 7kd5 A 1.551 BS06 PRO A 1 Y242 G243 Y241 G242 ? 0008643,0015144,0055085 A0A4P1LXE0,Q91MK1 34578318 1408 IEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAAKSSAASPAALSGYKMTLLALIKESIPNQAKRQKFEMQVGGIRNEQDFKNLRREIIRSAA 7kmh C 1.72 BS01 PRO C 1 F342 N343 S373 W436 F9 N10 S40 W103 ? P0DTC2 33820835 603 NLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPH 7osy A 2.23 BS01 PRO A 1 T1121 E1123 R1152 W1169 E1171 H1173 F1216 H1242 W1273 G1274 T106 E108 R137 W154 E156 H158 F201 H227 W258 G259 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 LEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGIEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDSMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7osy B 2.23 BS01 PRO B 1 T1121 E1123 R1152 W1169 E1171 H1173 F1216 H1242 W1273 G1274 T106 E108 R137 W154 E156 H158 F201 H227 W258 G259 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 LEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGILSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7osz A 2.46 BS01 PRO A 1 T1121 E1123 W1169 E1171 H1173 F1216 H1242 W1273 G1274 T106 E108 W154 E156 H158 F201 H227 W258 G259 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 LEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLESMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7osz B 2.46 BS01 PRO B 1 T1121 E1123 R1152 W1169 E1171 H1173 H1242 W1273 G1274 T107 E109 R138 W155 E157 H159 H228 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGILSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7ot0 A 2.32 BS01 PRO A 1 T1121 E1123 W1169 E1171 H1173 F1216 H1242 S1272 W1273 G1274 T107 E109 W155 E157 H159 F202 H228 S258 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7ot0 B 2.32 BS01 PRO B 1 T1121 E1123 W1169 E1171 H1173 F1216 H1242 S1272 W1273 G1274 T107 E109 W155 E157 H159 F202 H228 S258 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7ot1 A 2.71 BS01 PRO A 1 T1121 E1123 W1169 E1171 H1173 H1242 W1273 G1274 T106 E108 W154 E156 H158 H227 W258 G259 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 LEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTAMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7ot1 B 2.71 BS01 PRO B 1 T1121 E1123 R1152 W1169 E1171 H1173 F1216 H1242 W1273 G1274 T107 E109 R138 W155 E157 H159 F202 H228 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGILSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7ot2 A 2.48 BS01 PRO A 1 T1121 E1123 W1169 E1171 F1216 H1242 S1272 W1273 G1274 T107 E109 W155 E157 F202 H228 S258 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7ot2 B 2.48 BS01 PRO B 1 T1121 E1123 W1169 E1171 F1216 H1242 S1272 W1273 G1274 T106 E108 W154 E156 F201 H227 S257 W258 G259 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 LEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7ot3 A 2.53 BS01 PRO A 1 T1121 E1123 W1169 E1171 H1173 F1216 H1242 W1273 G1274 T107 E109 W155 E157 H159 F202 H228 W259 G260 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 GLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7ot3 B 2.53 BS01 PRO B 1 T1121 E1123 W1169 E1171 H1173 F1216 H1242 W1273 G1274 T106 E108 W154 E156 H158 F201 H227 W258 G259 6.1.1.15,6.1.1.17 0000166,0004812,0004827,0005524,0005737,0006418,0006433 P07814 34360555 1601 LEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTAMGAKSLCIPFKPLCELQPGAKCVCGKNPAKYYTLFGRSY 7ov0 A 0.95 BS01 PRO A 1 Q420 A423 G424 G425 Y432 Q198 A201 G202 G203 Y210 2.4.2.10,4.1.1.23 0004590,0006207,0044205 P11172 504 MELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV 7ov0 A 0.95 BS02 PRO A 2 G479 V480 G257 V258 2.4.2.10,4.1.1.23 0004590,0006207,0044205 P11172 506 MELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV 7pnd A 1.85 BS02 PRO A 1 Y45 T46 Y126 K127 V171 Y12 T13 Y93 K94 V131 ? 0006508,0008237,0008270 O86049 36173175 406 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDKYPVSVKINVDKAKKILNLPECDYINDYIKTPQVPHGITESQTRAVPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pnd A 1.85 BS03 PRO A 2 Y367 S368 K369 Y327 S328 K329 ? 0006508,0008237,0008270 O86049 36173175 407 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDKYPVSVKINVDKAKKILNLPECDYINDYIKTPQVPHGITESQTRAVPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pnd B 1.85 BS02 PRO B 1 S42 S44 D47 D160 S161 S9 S11 D14 D127 S128 ? 0006508,0008237,0008270 O86049 36173175 406 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSKYPVSVKINVDKAKKILNLPECDYINDYIKTPQEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pnd B 1.85 BS03 PRO B 2 S44 Y45 T46 K127 S11 Y12 T13 K94 ? 0006508,0008237,0008270 O86049 36173175 407 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSKYPVSVKINVDKAKKILNLPECDYINDYIKTPQEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pnd B 1.85 BS04 PRO B 3 D66 F69 F114 R116 I121 Y123 K174 D33 F36 F81 R83 I88 Y90 K135 ? 0006508,0008237,0008270 O86049 36173175 408 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSKYPVSVKINVDKAKKILNLPECDYINDYIKTPQEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pnd B 1.85 BS05 PRO B 4 E227 S230 R305 G307 E173 S176 R251 G253 ? 0006508,0008237,0008270 O86049 36173175 409 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSKYPVSVKINVDKAKKILNLPECDYINDYIKTPQEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pnd B 1.85 BS06 PRO B 5 N320 Y322 N323 T326 N388 N266 Y268 N269 T272 N334 ? 0006508,0008237,0008270 O86049 36173175 410 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSKYPVSVKINVDKAKKILNLPECDYINDYIKTPQEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pol A 1.95 BS04 PRO A 1 Y45 T46 K127 V171 Y12 T13 K94 V133 ? 0006508,0008237,0008270 O86049 36173175 406 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRKYPVSVKINVDKAKKILNLPECDYINPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pol A 1.95 BS05 PRO A 2 D360 D361 D302 D303 ? 0006508,0008237,0008270 O86049 36173175 407 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRKYPVSVKINVDKAKKILNLPECDYINPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pol A 1.95 BS06 PRO A 3 L377 E379 L319 E321 ? 0006508,0008237,0008270 O86049 36173175 408 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRKYPVSVKINVDKAKKILNLPECDYINPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pol B 1.95 BS04 PRO B 1 Y45 T46 Y126 K127 V171 Y11 T12 Y92 K93 V131 ? 0006508,0008237,0008270 O86049 36173175 403 TASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDGKYPVSVKINVDKAKKILNLPECDYVPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7poo B 2.7 BS03 PRO B 1 Y45 T46 K127 Y12 T13 K94 ? 0006508,0008237,0008270 O86049 36173175 406 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRKYPVSVKINVDKAKKILNLPECDYINPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7poq A 1.85 BS03 PRO A 1 G118 D178 G372 Y373 G85 D139 G319 Y320 ? 0006508,0008237,0008270 O86049 36173175 406 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSKYPVSVKINVDKAKKILNLPECDYINDYIKTVPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7poq A 1.85 BS04 PRO A 2 Y45 T46 Y126 K127 V171 Y12 T13 Y93 K94 V132 ? 0006508,0008237,0008270 O86049 36173175 407 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSKYPVSVKINVDKAKKILNLPECDYINDYIKTVPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pou A 2.03 BS03 PRO A 1 S44 Y45 T46 K127 S11 Y12 T13 K94 ? 0006508,0008237,0008270 O86049 36173175 405 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRTGKYPVSVKINVDKAKKILNLPECDYINDYIKTPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pou A 2.03 BS04 PRO A 2 G118 D178 G372 Y373 G85 D142 G321 Y322 ? 0006508,0008237,0008270 O86049 36173175 406 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRTGKYPVSVKINVDKAKKILNLPECDYINDYIKTPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pou A 2.03 BS05 PRO A 3 D39 Q41 K65 N67 D6 Q8 K32 N34 ? 0006508,0008237,0008270 O86049 36173175 407 VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRTGKYPVSVKINVDKAKKILNLPECDYINDYIKTPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pou B 2.03 BS03 PRO B 1 Y45 T46 K127 A129 Y14 T15 K96 A98 ? 0006508,0008237,0008270 O86049 36173175 406 APVTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRGKYPVSVKINVDKAKKILNLPECDYINDYIKTSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pou B 2.03 BS04 PRO B 2 D66 F69 F114 R116 I121 Y123 K174 D35 F38 F83 R85 I90 Y92 K139 ? 0006508,0008237,0008270 O86049 36173175 407 APVTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRGKYPVSVKINVDKAKKILNLPECDYINDYIKTSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pou B 2.03 BS05 PRO B 3 L377 E379 L326 E328 ? 0006508,0008237,0008270 O86049 36173175 408 APVTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRGKYPVSVKINVDKAKKILNLPECDYINDYIKTSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7pou B 2.03 BS06 PRO B 4 D360 D361 D309 D310 ? 0006508,0008237,0008270 O86049 36173175 409 APVTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRGKYPVSVKINVDKAKKILNLPECDYINDYIKTSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD 7q1h A 1.31 BS02 PRO A 1 Q420 A423 G424 G425 Y432 Q198 A201 G202 G203 Y210 2.4.2.10,4.1.1.23 0004590,0006207,0044205 P11172 503 MELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFENRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV 7qb7 A 1.9 BS01 PRO A 1 T359 E361 W407 E409 F454 H480 S508 W509 G510 T104 E106 W152 E154 F199 H225 S253 W254 G255 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 Q8I5R7 801 NILGITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKEFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLNTTLSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 7qc2 A 2.28 BS01 PRO A 1 T359 E361 W407 E409 F454 H480 W509 G510 T110 E112 W158 E160 F205 H231 W260 G261 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 Q8I5R7 801 NILGITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKEKNHIEGFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLNQSETTLSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 7ufj A 2.5 BS01 PRO A 1 Q268 V269 Q265 V266 ? Q95460 36403855 301 MRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIQEIDYGDILPSGDGTYQAWASIELDPNLYSCHVEHSGVHMVLQV 7v8j B 2.519 BS01 PRO B 1 H560 S588 W589 H216 S244 W245 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 901 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7v8k A 2.47 BS01 PRO A 1 T439 E441 W487 E489 F534 H560 S588 W589 G590 T98 E100 W144 E146 F191 H217 S245 W246 G247 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 901 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLESPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEITGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7v8k B 2.47 BS01 PRO B 1 F534 H560 W589 F190 H216 W245 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 901 VTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7vc1 A 1.892 BS02 PRO A 1 T439 E441 W487 E489 H491 F534 H560 W589 G590 T100 E102 W148 E150 H152 F195 H221 W250 G251 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 36854028 902 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKESPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIVMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7vc2 A 2.096 BS02 PRO A 1 T439 E441 W487 E489 F534 H560 S588 W589 G590 T99 E101 W147 E149 F194 H220 S248 W249 G250 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 36854028 902 AMVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7vc2 B 2.096 BS02 PRO B 1 T439 E441 W487 E489 F534 H560 W589 G590 T88 E90 W136 E138 F183 H209 W238 G239 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 36854028 902 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSVAWVTHYGDSPLPIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQATGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7vc3 A 1.973 BS02 PRO A 1 T439 E441 W487 E489 F534 H560 W589 G590 T99 E101 W147 E149 F194 H220 W249 G250 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433 A0A7J6JUK2 36854028 1002 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKEKEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEAGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 7xzp A 2.56 BS02 PRO A 1 R237 H242 R236 H241 6.3.4.3 0004329,0005524,0006730,0016874,0035999 A0A379CIH2 38049785 604 EFKTDIEIAQEANPQDIRDIAKKINLSEDDIELYGKYKAKIDYNVLNRTKSRAGKLILTTAINPTPAGEGKTTTSIGVADALAKLGKNVIAALREPSMGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDMHAIGAANNLLAAMLDNHVYQTNSLNINPKRITWRRCVDMNDRQLRNVVDGLGKKVDGVTREDGFDITVASEVMAAFCLSNNISELKENLGNIVVAYNYSGKPVTARDLNAHGAMAAILKDALKPNLVQTLEGTPAILHGGPFANIAHGCNSIIATKMGMHMADYVVTEAGFGADLGAEKFLDIKCRKAGIRPDAVIIVATVRALKYNGGVAKDQLNNENLEALEKGLPNLLKHIENITQVYKIPAVVAINRFPLDTDAELALVRSKCEELGVKVALSEVWANGGEGGIEVANEVLKLIEEGENNFEYCYEEDMTIKEKLNAIATKIYGADGVNYTKEANKQIAELEELGFGNLPVCVAKTQYSLSDDQTKLGRPTGFTIEVRQANISAGAGFVVVMTGEIMKMPGLPKLPAAERIDVDENGKISGLF 7xzp A 2.56 BS03 PRO A 2 K184 K185 K183 K184 6.3.4.3 0004329,0005524,0006730,0016874,0035999 A0A379CIH2 38049785 605 EFKTDIEIAQEANPQDIRDIAKKINLSEDDIELYGKYKAKIDYNVLNRTKSRAGKLILTTAINPTPAGEGKTTTSIGVADALAKLGKNVIAALREPSMGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDMHAIGAANNLLAAMLDNHVYQTNSLNINPKRITWRRCVDMNDRQLRNVVDGLGKKVDGVTREDGFDITVASEVMAAFCLSNNISELKENLGNIVVAYNYSGKPVTARDLNAHGAMAAILKDALKPNLVQTLEGTPAILHGGPFANIAHGCNSIIATKMGMHMADYVVTEAGFGADLGAEKFLDIKCRKAGIRPDAVIIVATVRALKYNGGVAKDQLNNENLEALEKGLPNLLKHIENITQVYKIPAVVAINRFPLDTDAELALVRSKCEELGVKVALSEVWANGGEGGIEVANEVLKLIEEGENNFEYCYEEDMTIKEKLNAIATKIYGADGVNYTKEANKQIAELEELGFGNLPVCVAKTQYSLSDDQTKLGRPTGFTIEVRQANISAGAGFVVVMTGEIMKMPGLPKLPAAERIDVDENGKISGLF 7xzp A 2.56 BS04 PRO A 3 Q11 P119 M120 E121 Q10 P118 M119 E120 6.3.4.3 0004329,0005524,0006730,0016874,0035999 A0A379CIH2 38049785 606 EFKTDIEIAQEANPQDIRDIAKKINLSEDDIELYGKYKAKIDYNVLNRTKSRAGKLILTTAINPTPAGEGKTTTSIGVADALAKLGKNVIAALREPSMGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDMHAIGAANNLLAAMLDNHVYQTNSLNINPKRITWRRCVDMNDRQLRNVVDGLGKKVDGVTREDGFDITVASEVMAAFCLSNNISELKENLGNIVVAYNYSGKPVTARDLNAHGAMAAILKDALKPNLVQTLEGTPAILHGGPFANIAHGCNSIIATKMGMHMADYVVTEAGFGADLGAEKFLDIKCRKAGIRPDAVIIVATVRALKYNGGVAKDQLNNENLEALEKGLPNLLKHIENITQVYKIPAVVAINRFPLDTDAELALVRSKCEELGVKVALSEVWANGGEGGIEVANEVLKLIEEGENNFEYCYEEDMTIKEKLNAIATKIYGADGVNYTKEANKQIAELEELGFGNLPVCVAKTQYSLSDDQTKLGRPTGFTIEVRQANISAGAGFVVVMTGEIMKMPGLPKLPAAERIDVDENGKISGLF 7xzp A 2.56 BS05 PRO A 4 R173 R176 R172 R175 6.3.4.3 0004329,0005524,0006730,0016874,0035999 A0A379CIH2 38049785 607 EFKTDIEIAQEANPQDIRDIAKKINLSEDDIELYGKYKAKIDYNVLNRTKSRAGKLILTTAINPTPAGEGKTTTSIGVADALAKLGKNVIAALREPSMGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDMHAIGAANNLLAAMLDNHVYQTNSLNINPKRITWRRCVDMNDRQLRNVVDGLGKKVDGVTREDGFDITVASEVMAAFCLSNNISELKENLGNIVVAYNYSGKPVTARDLNAHGAMAAILKDALKPNLVQTLEGTPAILHGGPFANIAHGCNSIIATKMGMHMADYVVTEAGFGADLGAEKFLDIKCRKAGIRPDAVIIVATVRALKYNGGVAKDQLNNENLEALEKGLPNLLKHIENITQVYKIPAVVAINRFPLDTDAELALVRSKCEELGVKVALSEVWANGGEGGIEVANEVLKLIEEGENNFEYCYEEDMTIKEKLNAIATKIYGADGVNYTKEANKQIAELEELGFGNLPVCVAKTQYSLSDDQTKLGRPTGFTIEVRQANISAGAGFVVVMTGEIMKMPGLPKLPAAERIDVDENGKISGLF 7xzp A 2.56 BS06 PRO A 5 Y150 Q151 Y149 Q150 6.3.4.3 0004329,0005524,0006730,0016874,0035999 A0A379CIH2 38049785 608 EFKTDIEIAQEANPQDIRDIAKKINLSEDDIELYGKYKAKIDYNVLNRTKSRAGKLILTTAINPTPAGEGKTTTSIGVADALAKLGKNVIAALREPSMGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDMHAIGAANNLLAAMLDNHVYQTNSLNINPKRITWRRCVDMNDRQLRNVVDGLGKKVDGVTREDGFDITVASEVMAAFCLSNNISELKENLGNIVVAYNYSGKPVTARDLNAHGAMAAILKDALKPNLVQTLEGTPAILHGGPFANIAHGCNSIIATKMGMHMADYVVTEAGFGADLGAEKFLDIKCRKAGIRPDAVIIVATVRALKYNGGVAKDQLNNENLEALEKGLPNLLKHIENITQVYKIPAVVAINRFPLDTDAELALVRSKCEELGVKVALSEVWANGGEGGIEVANEVLKLIEEGENNFEYCYEEDMTIKEKLNAIATKIYGADGVNYTKEANKQIAELEELGFGNLPVCVAKTQYSLSDDQTKLGRPTGFTIEVRQANISAGAGFVVVMTGEIMKMPGLPKLPAAERIDVDENGKISGLF 7xzp B 2.56 BS01 PRO A 4 Y150 V186 Y151 V187 6.3.4.3 0004329,0005524,0006730,0016874,0035999 A0A379CIH2 38049785 607 MMEFKTDIEIAQEANPQDIRDIAKKINLSEDDIELYGKYKAKIDYNVLNRTKSRAGKLILTTAINPTPAGEGKTTTSIGVADALAKLGKNVIAALREPSMGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDMHAIGAANNLLAAMLDNHVYQTNSLNINPKRITWRRCVDMNDRQLRNVVDGLGKKVDGVTREDGFDITVASEVMAAFCLSNNISELKENLGNIVVAYNYSGKPVTARDLNAHGAMAAILKDALKPNLVQTLEGTPAILHGGPFANIAHGCNSIIATKMGMHMADYVVTEAGFGADLGAEKFLDIKCRKAGIRPDAVIIVATVRALKYNGGVAKDQLNNENLEALEKGLPNLLKHIENITQVYKIPAVVAINRFPLDTDAELALVRSKCEELGVKVALSEVWANGGEGGIEVANEVLKLIEEGENNFEYCYEEDMTIKEKLNAIATKIYGADGVNYTKEANKQIAELEELGFGNLPVCVAKTQYSLSDDQTKLGRPTGFTIEVRQANISAGAGFVVVMTGEIMKMPGLPKLPAAERIDVDENGKISGLF 7xzp B 2.56 BS04 PRO B 1 E218 R237 H242 E219 R238 H243 6.3.4.3 0004329,0005524,0006730,0016874,0035999 A0A379CIH2 38049785 604 MMEFKTDIEIAQEANPQDIRDIAKKINLSEDDIELYGKYKAKIDYNVLNRTKSRAGKLILTTAINPTPAGEGKTTTSIGVADALAKLGKNVIAALREPSMGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDMHAIGAANNLLAAMLDNHVYQTNSLNINPKRITWRRCVDMNDRQLRNVVDGLGKKVDGVTREDGFDITVASEVMAAFCLSNNISELKENLGNIVVAYNYSGKPVTARDLNAHGAMAAILKDALKPNLVQTLEGTPAILHGGPFANIAHGCNSIIATKMGMHMADYVVTEAGFGADLGAEKFLDIKCRKAGIRPDAVIIVATVRALKYNGGVAKDQLNNENLEALEKGLPNLLKHIENITQVYKIPAVVAINRFPLDTDAELALVRSKCEELGVKVALSEVWANGGEGGIEVANEVLKLIEEGENNFEYCYEEDMTIKEKLNAIATKIYGADGVNYTKEANKQIAELEELGFGNLPVCVAKTQYSLSDDQTKLGRPTGFTIEVRQANISAGAGFVVVMTGEIMKMPGLPKLPAAERIDVDENGKISGLF 7xzp B 2.56 BS05 PRO B 2 R173 R176 M532 R174 R177 M533 6.3.4.3 0004329,0005524,0006730,0016874,0035999 A0A379CIH2 38049785 605 MMEFKTDIEIAQEANPQDIRDIAKKINLSEDDIELYGKYKAKIDYNVLNRTKSRAGKLILTTAINPTPAGEGKTTTSIGVADALAKLGKNVIAALREPSMGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDMHAIGAANNLLAAMLDNHVYQTNSLNINPKRITWRRCVDMNDRQLRNVVDGLGKKVDGVTREDGFDITVASEVMAAFCLSNNISELKENLGNIVVAYNYSGKPVTARDLNAHGAMAAILKDALKPNLVQTLEGTPAILHGGPFANIAHGCNSIIATKMGMHMADYVVTEAGFGADLGAEKFLDIKCRKAGIRPDAVIIVATVRALKYNGGVAKDQLNNENLEALEKGLPNLLKHIENITQVYKIPAVVAINRFPLDTDAELALVRSKCEELGVKVALSEVWANGGEGGIEVANEVLKLIEEGENNFEYCYEEDMTIKEKLNAIATKIYGADGVNYTKEANKQIAELEELGFGNLPVCVAKTQYSLSDDQTKLGRPTGFTIEVRQANISAGAGFVVVMTGEIMKMPGLPKLPAAERIDVDENGKISGLF 7xzp B 2.56 BS06 PRO B 3 F436 Y438 F437 Y439 6.3.4.3 0004329,0005524,0006730,0016874,0035999 A0A379CIH2 38049785 606 MMEFKTDIEIAQEANPQDIRDIAKKINLSEDDIELYGKYKAKIDYNVLNRTKSRAGKLILTTAINPTPAGEGKTTTSIGVADALAKLGKNVIAALREPSMGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDMHAIGAANNLLAAMLDNHVYQTNSLNINPKRITWRRCVDMNDRQLRNVVDGLGKKVDGVTREDGFDITVASEVMAAFCLSNNISELKENLGNIVVAYNYSGKPVTARDLNAHGAMAAILKDALKPNLVQTLEGTPAILHGGPFANIAHGCNSIIATKMGMHMADYVVTEAGFGADLGAEKFLDIKCRKAGIRPDAVIIVATVRALKYNGGVAKDQLNNENLEALEKGLPNLLKHIENITQVYKIPAVVAINRFPLDTDAELALVRSKCEELGVKVALSEVWANGGEGGIEVANEVLKLIEEGENNFEYCYEEDMTIKEKLNAIATKIYGADGVNYTKEANKQIAELEELGFGNLPVCVAKTQYSLSDDQTKLGRPTGFTIEVRQANISAGAGFVVVMTGEIMKMPGLPKLPAAERIDVDENGKISGLF 7xzp B 2.56 BS07 PRO B 4 M290 I321 R322 D324 M291 I322 R323 D325 6.3.4.3 0004329,0005524,0006730,0016874,0035999 A0A379CIH2 38049785 607 MMEFKTDIEIAQEANPQDIRDIAKKINLSEDDIELYGKYKAKIDYNVLNRTKSRAGKLILTTAINPTPAGEGKTTTSIGVADALAKLGKNVIAALREPSMGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDMHAIGAANNLLAAMLDNHVYQTNSLNINPKRITWRRCVDMNDRQLRNVVDGLGKKVDGVTREDGFDITVASEVMAAFCLSNNISELKENLGNIVVAYNYSGKPVTARDLNAHGAMAAILKDALKPNLVQTLEGTPAILHGGPFANIAHGCNSIIATKMGMHMADYVVTEAGFGADLGAEKFLDIKCRKAGIRPDAVIIVATVRALKYNGGVAKDQLNNENLEALEKGLPNLLKHIENITQVYKIPAVVAINRFPLDTDAELALVRSKCEELGVKVALSEVWANGGEGGIEVANEVLKLIEEGENNFEYCYEEDMTIKEKLNAIATKIYGADGVNYTKEANKQIAELEELGFGNLPVCVAKTQYSLSDDQTKLGRPTGFTIEVRQANISAGAGFVVVMTGEIMKMPGLPKLPAAERIDVDENGKISGLF 8h7y A 2.14 BS03 PRO A 1 Q97 D116 F119 W120 T172 R246 Q98 D117 F120 W121 T173 R247 ? 0046872,0051213 S5TUM1 36974966 303 QIMEPHDTLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVENTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKINAKRAFKGEVWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADVKGEGWANTLTASLKYSLDVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 8h7y B 2.14 BS03 PRO B 1 Q97 D116 F119 W120 T172 R246 Q99 D118 F121 W122 T174 R247 ? 0046872,0051213 S5TUM1 36974966 303 QIMEPHDTLSPAQVDEYRKNGFLVQEHVFDEEEIELLRAEAAQEFASGGERVTVEQNTGIVRGVHGCHLYSEVFGRLVRSPRLLPIARQLLRDDVYVHQFKINAKRAFKGEVWEWHQDYTFWHHEDGMPAPRALSAAIFLDEVTEFNGPLTFVPGGHGSGMIDADVKGEGWANTLTASLKYSLVETMRGLIERNGMVAPKGPRGSVLWFDANIPHSSVPNISPFDRGLVLITYNSVENKTDVTRGTRPEWLAARDFTPLTALQATSF 8hrh B 2.07 BS02 PRO B 1 H31 N33 Y37 H31 N33 Y37 37547453 301 DVLMTQTPLSLPVSLGDQASISCRSSQSIVHSNGNTYLEWYLQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYYCFQGSHGPWTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 8i91 B 3.3 BS01 PRO B 1 Y21 G24 Y102 F250 S251 S406 Y17 G20 Y98 F246 S247 S402 ? 0005298,0005515,0005886,0006865,0015171,0015175,0015188,0015193,0015199,0015293,0015370,0015816,0015824,0015838,0016020,0016324,0022857,0035725,0089718,0150104,1903804,1903806,1904271,1905647 Q9NP91 37684251 701 RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVCPLNGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAALGTFVQRRL 8i91 D 3.3 BS01 PRO D 1 Y21 G24 Y102 F250 S251 S406 Y17 G20 Y98 F246 S247 S402 ? 0005298,0005515,0005886,0006865,0015171,0015175,0015188,0015193,0015199,0015293,0015370,0015816,0015824,0015838,0016020,0016324,0022857,0035725,0089718,0150104,1903804,1903806,1904271,1905647 Q9NP91 37684251 701 RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVCPLNGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAALGTFVQRRL 8jv2 A 1.3 BS01 PRO A 1 W29 Y33 W246 R249 E272 Y310 W8 Y12 W225 R228 E251 Y289 B6BQH5 501 GAVTVVSWGGAYTESQKLGYGDPTAAKLGIPVNWVDYTGGLSEIKAQKEAGAITWDIMDVYAKDTIIGCDEGIFHEFDFDKDFLPAPDGTPASQDFFTSMPSKCAVGNILYSWNFAYNDAKIGDKKPKSIKDFFNTKKFPGKRAIYKGAMSNLEIALVADGVKASGAQAGGDLLYRKMEGAGIDRALAKIKKLCTDPNGGCVFWNAGAQPPELLANGEVVMATGWNGRFFNAQMEGTPLVQVWDAQILDYEYFALVKDGPGYADGSAMKVLAEMTSTEGLAGSAKYIAYAPWRKSSIAIMEAGEPWFKDGKTNMVPHMPTAPSNLKSHILMNPDYWADNQDEINEKWEAMKAGLHHHHHH 8qh0 A 1.87 BS01 PRO A 1 N388 G526 N56 G194 P0DTC2 601 TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSFLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCG 8u7b B 2.66 BS01 PRO B 1 R19 W20 R18 W19 ? A0A1I7NFG5 38844755 501 RNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLFWSTIEKEIRENTCKFLIVSSTAGNKREGVLKELAVATKVKKHLQDDMFIIPLAIDENLSYDDINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKSNLLYQQIFLHDKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDVRTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIRISTSDILSGRYDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKLEKDKFEKIKLVGKQKNKYWHFGISAAGKLYPSPVLMVSSHIIFTMDGINLIKSSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDQNAIYLNVGSEEKILISNKPLKFFGKMSYVTPSEVTLEEESVLAD 8u7b B 2.66 BS02 PRO B 2 E31 V32 E30 V31 ? A0A1I7NFG5 38844755 502 RNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLFWSTIEKEIRENTCKFLIVSSTAGNKREGVLKELAVATKVKKHLQDDMFIIPLAIDENLSYDDINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKSNLLYQQIFLHDKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDVRTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIRISTSDILSGRYDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKLEKDKFEKIKLVGKQKNKYWHFGISAAGKLYPSPVLMVSSHIIFTMDGINLIKSSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDQNAIYLNVGSEEKILISNKPLKFFGKMSYVTPSEVTLEEESVLAD 8u7b B 2.66 BS03 PRO B 3 Y105 V113 R114 N116 Y99 V107 R108 N110 ? A0A1I7NFG5 38844755 503 RNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLFWSTIEKEIRENTCKFLIVSSTAGNKREGVLKELAVATKVKKHLQDDMFIIPLAIDENLSYDDINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKSNLLYQQIFLHDKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDVRTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIRISTSDILSGRYDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKLEKDKFEKIKLVGKQKNKYWHFGISAAGKLYPSPVLMVSSHIIFTMDGINLIKSSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDQNAIYLNVGSEEKILISNKPLKFFGKMSYVTPSEVTLEEESVLAD 8u7b B 2.66 BS04 PRO B 4 M287 H340 M281 H334 ? A0A1I7NFG5 38844755 504 RNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLFWSTIEKEIRENTCKFLIVSSTAGNKREGVLKELAVATKVKKHLQDDMFIIPLAIDENLSYDDINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKSNLLYQQIFLHDKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDVRTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIRISTSDILSGRYDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKLEKDKFEKIKLVGKQKNKYWHFGISAAGKLYPSPVLMVSSHIIFTMDGINLIKSSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDQNAIYLNVGSEEKILISNKPLKFFGKMSYVTPSEVTLEEESVLAD 8u7b B 2.66 BS05 PRO C 1 K24 L28 H147 K23 L27 H141 ? A0A1I7NFG5 38844755 603 RNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLFWSTIEKEIRENTCKFLIVSSTAGNKREGVLKELAVATKVKKHLQDDMFIIPLAIDENLSYDDINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKSNLLYQQIFLHDKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDVRTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIRISTSDILSGRYDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKLEKDKFEKIKLVGKQKNKYWHFGISAAGKLYPSPVLMVSSHIIFTMDGINLIKSSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDQNAIYLNVGSEEKILISNKPLKFFGKMSYVTPSEVTLEEESVLAD 8u7b C 2.66 BS02 PRO C 2 R243 F245 R243 F245 ? A0A1I7NFD7 38844755 604 MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGLQIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITDEEIRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPEEIYKYCRPNSVLPNELVQTKSLISKSKAKSFRYTPTLFEEFNKKLKEVEKEAKTYNYDAQFHDQLKARLLEHTIPTQILRESTLAWRDFKNTFGAPIRDFSKIEGHLAWTISTAAYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFLDNGDGTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQALESYKEQNKSYPKEVFIHARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPLKLYKTEGAFPIMRGNAYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQVLKDILALTKLNYNACIYADGEPVTLRFANKIGEILTASTEIKTPPLAFKYYI 8wko A 2.91 BS02 PRO B 1 H216 Q287 S291 H213 Q284 S288 ? 0003824,0003961,0006520,0016765,0018826,0019346,0030170,0071266 A0A0G9F7S9 38568076 504 TTNPENYHFETLQVHAGQTVDETGARAVPIYQTTSYVFKDAKQAAGRFALTDAGNIYTRLTNPTTDVVDKRVAALEHGTAGVTLATGSAAITAAILNIAQQGDEIVAANTLYGGTYDLFSVTLKKLGITTHFVDPDEPANFETAINDHTKALYVESIGNPGINLVDFEAIGKIAHDHGIIFIVDNTFGTPYLVRPLEHGADVVVHSATFIGGHGTTMGGVIVEGGQFDWRASGKYPDFTTPDPQYNGLVFADLGGAAFTTKVRAETLRDTGATISPFNSFLLLQGLESLSLRVERHVTNTRKIVAFLKAHPKVAWINYPELEDSPYHDLATKYFPNGVGSIFTLGLTGGEAAGKALIEHLQLFSLLANVADAKSLIIHPASTTHAQLNEQELLAAGVTPDLIRISVGVENADDLIADLDQALAQV 8wko B 2.91 BS01 PRO B 1 H216 Q287 S291 H212 Q283 S287 ? 0003824,0003961,0006520,0016765,0018826,0019346,0030170,0071266 A0A0G9F7S9 38568076 504 TNPENYHFETLQVHAGQTVDETGARAVPIYQTTSYVFKDAKQAAGRFALTDAGNIYTRLTNPTTDVVDKRVAALEHGTAGVTLATGSAAITAAILNIAQQGDEIVAANTLYGGTYDLFSVTLKKLGITTHFVDPDEPANFETAINDHTKALYVESIGNPGINLVDFEAIGKIAHDHGIIFIVDNTFGTPYLVRPLEHGADVVVHSATFIGGHGTTMGGVIVEGGQFDWRASGKYPDFTTPDPQYNGLVFADLGGAAFTTKVRAETLRDTGATISPFNSFLLLQGLESLSLRVERHVTNTRKIVAFLKAHPKVAWINYPELEDSPYHDLATKYFPNGVGSIFTLGLTGGEAAGKALIEHLQLFSLLANVADAKSLIIHPASTTHAQLNEQELLAAGVTPDLIRISVGVENADDLIADLDQALAQV 8wkr A 2.05 BS02 PRO B 1 H216 Q287 G288 S291 H192 Q263 G264 S267 ? 0003824,0003961,0006520,0016765,0018826,0019346,0030170,0071266 A0A0G9F7S9 38568076 501 NPENYHFETLQVHAGQTVDETGARAVPIYQTTSYVFKRLTNPTTDVVDKRVAALEHGTAGVTLATGSAAITAAILNIAQQGDEIVAANTLYGGTYDLFSVTLKKLGITTHFVDPDEPANFETAINDHTKALYVESIGNPGINLVDFEAIGKIAHDHGIIFIVDNTFGTPYLVRPLEHGADVVVHSATFIGGHGTTMGGVIVEGGQFDWRASGKYPDFTTPDPQYNGLVFADLGGAAFTTKVRAETLRDTGATISPFNSFLLLQGLESLSLRVERHVTNTRKIVAFLKAHPKVAWINYPELEDSPYHDLATKYFPNGVGSIFTLGLTGGEAAGKALIEHLQLFSLLANVADAKSLIIHPASTTHAQLNEQELLAAGVTPDLIRISVGVENADDLIADLDQALAQV 8wkr B 2.05 BS01 PRO B 1 H216 Q287 S291 H192 Q263 S267 ? 0003824,0003961,0006520,0016765,0018826,0019346,0030170,0071266 A0A0G9F7S9 38568076 501 NPENYHFETLQVHAGQTVDETGARAVPIYQTTSYVFKRLTNPTTDVVDKRVAALEHGTAGVTLATGSAAITAAILNIAQQGDEIVAANTLYGGTYDLFSVTLKKLGITTHFVDPDEPANFETAINDHTKALYVESIGNPGINLVDFEAIGKIAHDHGIIFIVDNTFGTPYLVRPLEHGADVVVHSATFIGGHGTTMGGVIVEGGQFDWRASGKYPDFTTPDPQYNGLVFADLGGAAFTTKVRAETLRDTGATISPFNSFLLLQGLESLSLRVERHVTNTRKIVAFLKAHPKVAWINYPELEDSPYHDLATKYFPNGVGSIFTLGLTGGEAAGKALIEHLQLFSLLANVADAKSLIIHPASTTHAQLNEQELLAAGVTPDLIRISVGVENADDLIADLDQALAQV 8wkr C 2.05 BS02 PRO D 1 H216 Q287 S291 H192 Q263 S267 ? 0003824,0003961,0006520,0016765,0018826,0019346,0030170,0071266 A0A0G9F7S9 38568076 501 NPENYHFETLQVHAGQTVDETGARAVPIYQTTSYVFKRLTNPTTDVVDKRVAALEHGTAGVTLATGSAAITAAILNIAQQGDEIVAANTLYGGTYDLFSVTLKKLGITTHFVDPDEPANFETAINDHTKALYVESIGNPGINLVDFEAIGKIAHDHGIIFIVDNTFGTPYLVRPLEHGADVVVHSATFIGGHGTTMGGVIVEGGQFDWRASGKYPDFTTPDPQYNGLVFADLGGAAFTTKVRAETLRDTGATISPFNSFLLLQGLESLSLRVERHVTNTRKIVAFLKAHPKVAWINYPELEDSPYHDLATKYFPNGVGSIFTLGLTGGEAAGKALIEHLQLFSLLANVADAKSLIIHPASTTHAQLNEQELLAAGVTPDLIRISVGVENADDLIADLDQALAQV 8wkr D 2.05 BS01 PRO D 1 H216 Q287 S291 H192 Q263 S267 ? 0003824,0003961,0006520,0016765,0018826,0019346,0030170,0071266 A0A0G9F7S9 38568076 501 NPENYHFETLQVHAGQTVDETGARAVPIYQTTSYVFKRLTNPTTDVVDKRVAALEHGTAGVTLATGSAAITAAILNIAQQGDEIVAANTLYGGTYDLFSVTLKKLGITTHFVDPDEPANFETAINDHTKALYVESIGNPGINLVDFEAIGKIAHDHGIIFIVDNTFGTPYLVRPLEHGADVVVHSATFIGGHGTTMGGVIVEGGQFDWRASGKYPDFTTPDPQYNGLVFADLGGAAFTTKVRAETLRDTGATISPFNSFLLLQGLESLSLRVERHVTNTRKIVAFLKAHPKVAWINYPELEDSPYHDLATKYFPNGVGSIFTLGLTGGEAAGKALIEHLQLFSLLANVADAKSLIIHPASTTHAQLNEQELLAAGVTPDLIRISVGVENADDLIADLDQALAQV 8y0p A 2.62 BS02 PRO A 1 M271 R274 M123 R126 ? 0007155,0045296 P35222 701 ATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMS 8y0p A 2.62 BS03 PRO A 2 V291 Y331 T332 V143 Y183 T184 ? 0007155,0045296 P35222 703 ATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMS 8y0p B 2.62 BS01 PRO B 1 W504 I507 W356 I359 ? 0007155,0045296 P35222 701 ATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSED 8z10 A 2.35 BS01 PRO A 1 R457 E458 D459 R309 E310 D311 ? P35222 701 ATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSED 9bul A 2.1 BS03 PRO A 1 L11 K12 L48 Y53 L6 K7 L43 Y48 0003677,0046872 Q9X1T8 203 VRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGGKSGVSRLVAVKHAPEEIKEELLCVVRNGGRIVDVIVEHPVYGEIRGIIDVSSEEEVLKFVNLMEMAKTEPLLTLSGGVHLHTIEAPDEETMERIMRELKKKGFLIE