2h3q A -1.00 BS01 PBU A 1 R22 W36 S77 T81 R21 W35 S76 T80 2.7.7.-,2.7.7.49,2.7.7.7,3.1.-.-,3.1.13.2,3.1.26.13,3.4.23.16 0005198 P12497 16840558 300 GARASVLSGGELDKWEKIRLRPGGKKQYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTIAVLYCVHQRIDVKDTKEALDKIEEEQNKSKKKAQQAAADTGNNSQVSQNY 2h3z A -1.00 BS01 PBU A 1 R22 K32 W36 T81 R21 K31 W35 T80 2.7.7.-,2.7.7.49,2.7.7.7,3.1.-.-,3.1.13.2,3.1.26.13,3.4.23.16 0005198 P12497 16840558 300 GARASVLSGGELDKWEKIRLRPGGKKQYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTIAVLYCVHQRIDVKDTKEALDKIEEEQNKSKKKAQQAAADTGNNSQVSQNY 2k4i A -1.00 BS01 PBU A 1 L21 R22 K27 H33 W36 S77 N80 T81 L20 R21 K26 H32 W35 S76 N79 T80 2.7.7.-,2.7.7.49,2.7.7.7,3.1.-.-,3.1.13.2,3.1.26.13,3.4.23.47 0005198 -logKd/Ki=3.84, Kd=143uM P04584 18657545 300 GARNSVLRGKKADELERIRLRPGGKKKYRLKHIVWAANKLDRFGLAESLLESKEGCQKILTVLDPMVPTGSENLKSLFNTVCVIWCIHAEEKVKDTEGAKQIVRRHLVAETGTAEKMPSTSRPTAPSSEKGGNY 3w68 A 2.05 BS04 PBU B 1 T172 P173 T148 P149 ? 0001890,0001892,0005546,0005737,0008289,0008431,0009636,0042360,0043325,0051180,0090212,0120009,0120013,1900223 Q8BWP5 23599266 302 QPGLAELRRRVQEAGVPQTPQPLTDAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSADLRPRSILGLLKAGYHGVLRSRDSTGSRVLIYRIAYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQVSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYKSSMLQHFPDILPREYGGKEFSMEDICQEWTNFIMKSEDYLSSISE 3w68 B 2.05 BS02 PBU B 1 S208 M209 K211 S186 M187 K189 ? 0001890,0001892,0005546,0005737,0008289,0008431,0009636,0042360,0043325,0051180,0090212,0120009,0120013,1900223 Q8BWP5 23599266 302 LLQPGLAELRRRVQEAGVPQTPQPLTDAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSADLRPRSILGLLKAGYHGVLRSRDSTGSRVLIYRIAYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQVSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYKSSMLQHFPDILPREYGGKEFSMEDICQEWTNFIMKSEDYLSSISE 4ovv A 3.5 BS01 PBU A 1 G12 E722 G26 E711 2.7.11.1,2.7.1.137,2.7.1.153 0001525,0001889,0001944,0004674,0005515,0005524,0005737,0005829,0005886,0005942,0005943,0005944,0006006,0006629,0006909,0007173,0008286,0010468,0010592,0010629,0014704,0014823,0014870,0016242,0016301,0016303,0016310,0030027,0030036,0030168,0030295,0030835,0031295,0032008,0032869,0035005,0035994,0036092,0038084,0040014,0043201,0043276,0043457,0043491,0043524,0043542,0043560,0044024,0046854,0046934,0048009,0048015,0048471,0048661,0050852,0051897,0055119,0060048,0060612,0071333,0071464,0071548,0086003,0097009,0106310,0110053,0141068,1903544,1905477,2000270,2000811 P42336 25105564 1101 MSYYHHHHHHDYDIPTTRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTT 5c79 A 1.6 BS01 PBU A 1 K348 S350 R354 R360 H373 A374 R407 K15 S17 R21 R27 H40 A41 R74 ? 0005096,0043547 Kd=7uM Q9QWY8 26365802 800 GNKEYGSEKKGFLLKKSDGIRKVWQRRKCAVKNGILTISHATSNRQPAKLNLLTCQVKPNAEDKKSFDLISHNRTYHFQAEDEQDYIAWISVLTNSKEEALTMA 5c79 B 1.6 BS01 PBU B 1 K348 S350 D351 G352 R360 H373 A374 R378 R407 K15 S17 D18 G19 R27 H40 A41 R45 R74 ? 0005096,0043547 Kd=7uM Q9QWY8 26365802 502 GNKEYGSEKKGFLLKKSDGIRKVWQRRKCAVKNGILTISHATSNRQPAKLNLLTCQVKPNAEDKKSFDLISHNRTYHFQAEDEQDYIAWISVLTNSKEEALTM 5c79 B 1.6 BS02 PBU B 2 K349 K355 W357 Q412 K16 K22 W24 Q79 ? 0005096,0043547 Kd=7uM Q9QWY8 26365802 503 GNKEYGSEKKGFLLKKSDGIRKVWQRRKCAVKNGILTISHATSNRQPAKLNLLTCQVKPNAEDKKSFDLISHNRTYHFQAEDEQDYIAWISVLTNSKEEALTM