1ius A 2.2 BS02 PAB A 1 Y201 L210 S212 R214 Y222 P293 Y201 L210 S212 R214 Y222 P293 H72 Y201 P293 K297 Y385 H72 Y201 P293 K297 Y385 1.14.13.2 0004497,0009056,0016491,0016709,0018659,0043639,0043640,0050660,0071949,0106356 P20586 8555229 396 MKTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQGMVDLLREAGVDRRMARDGLVHEGVEIAFAGQRRRIDLKRLSGGKTVTVYGQTEVTRDLMEAREACGATTVYQAAEVRLHDLQGERPYVTFERDGERLRLDCDYIAGCDGFHGISRQSIPAERLKVFERVYPFGWLGLLADTPPVSHELIYANHPRGFALCSQRSATRSRYYVQVPLSEKVEDWSDERFWTELKARLPSEVAEKLVTGPSLEKSIAPLRSFVVEPMQHGRLFLAGDAAHIVPPTGAKGLNLAASDVSTLYRLLLKAYREGRGELLERYSAICLRRIWKAERFSWWMTSVLHRFPDTDAFSQRIQQTELEYYLGSEAGLATIAENYVGLPYEEIE 1iut A 2.0 BS02 PAB A 1 L199 Y201 L210 S212 R214 Y222 P293 L199 Y201 L210 S212 R214 Y222 P293 H72 Y201 P293 K297 Y385 H72 Y201 P293 K297 Y385 1.14.13.2 0004497,0009056,0016491,0016709,0018659,0043639,0043640,0050660,0071949,0106356 Kd=24uM P20586 8555229 396 MKTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQGMVDLLREAGVDRRMARDGLVHEGVEIAFAGQRRRIDLKRLSGGKTVTVYGQTEVTRDLMEAREACGATTVYQAAEVRLHDLQGERPYVTFERDGERLRLDCDYIAGCDGFHGISRQSIPAERLKVFERVYPFGWLGLLADTPPVSHELIYANHPRGFALCSQRSATRSRYYVQVPLSEKVEDWSDERFWTELKARLPSEVAEKLVTGPSLEKSIAPLRSFVVEPMQHGRLFLAGDAAHIVPPTGAKGLNLAASDVSTLYRLLLKAYREGRGELLERYSAICLRRIWKAERFSWWMTSVLHRFPDTDAFSQRIQQTELEYYLGSEAGLATIAENYVGLPYEEIE 1iuu A 2.0 BS02 PAB A 1 L199 Y201 L210 S212 R214 Y222 P293 L199 Y201 L210 S212 R214 Y222 P293 H72 Y201 P293 K297 Y385 H72 Y201 P293 K297 Y385 1.14.13.2 0004497,0009056,0016491,0016709,0018659,0043639,0043640,0050660,0071949,0106356 Kd=147uM P20586 8555229 396 MKTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQGMVDLLREAGVDRRMARDGLVHEGVEIAFAGQRRRIDLKRLSGGKTVTVYGQTEVTRDLMEAREACGATTVYQAAEVRLHDLQGERPYVTFERDGERLRLDCDYIAGCDGFHGISRQSIPAERLKVFERVYPFGWLGLLADTPPVSHELIYANHPRGFALCSQRSATRSRYYVQVPLSEKVEDWSDERFWTELKARLPSEVAEKLVTGPSLEKSIAPLRSFVVEPMQHGRLFLAGDAAHIVPPTGAKGLNLAASDVSTLYRLLLKAYREGRGELLERYSAICLRRIWKAERFSWWMTSVLHRFPDTDAFSQRIQQTELEYYLGSEAGLATIAENYVGLPYEEIE 1pbd A 2.3 BS02 PAB A 1 V47 L199 Y201 L210 S212 R214 Y222 P293 T294 V47 L199 Y201 L210 S212 R214 Y222 P293 T294 H72 Y201 P293 K297 Y385 H72 Y201 P293 K297 Y385 1.14.13.2 0004497,0009056,0016491,0016709,0018659,0043639,0043640,0050660,0071949,0106356 P00438 7520279 396 MKTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQGMVDLLREAGVDRRMARDGLVHEGVEIAFAGQRRRIDLKRLSGGKTVTVYGQTEVTRDLMEAREASGATTVYQAAEVRLHDLQGERPYVTFERDGERLRLDCDYIAGCDGFHGISRQSIPAERLKVFERVYPFGWLGLLADTPPVSHELIYANHPRGFALCSQRSATRSRYYVQVPLTEKVEDWSDERFWTELKARLPAEVAEKLVTGPSLEKSIAPLRSFVVEPMQHGRLFLAGDAAHIVPPTGAKGLNLAASDVSTLYRLLLKAYREGRGELLERYSAICLRRIWKAERFSWWMTSVLHRFPDTDAFSQRIQQTELEYYLGSEAGLATIAENYVGLPYE 2dza B 1.9 BS01 PAB B 1 T76 R77 P78 F202 K233 R234 T50 R51 P52 F173 K204 R205 K233 R268 K204 R239 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 Q5SLV2 1301 RTLWLRDRALDLDRVRLLGVLNLTPDSALERAREMVAEGADILDLGAESTRPPVPVEEEKRRLLPVLEAVLSLGVPVSVDTRKPEVAEEALKLGAHLLNDVTGLRDERMVALAARHGVAAVVMHMPVPDPATMMAHARYRDVVAEVKAFLEAQARRALSAGVPQVVLDPGFGFGKLLEHNLALLRRLDEIVALGHPVLVGLSRKRTIGELSGVEDPAQRVHGSVAAHLFAVMKGVRLLRVHDVRAHREALGVWEALY 3q2a A 1.99 BS03 PAB A 1 W338 E391 T392 L393 T463 L464 W337 E390 T391 L392 T462 L463 E104 E134 H137 E197 E231 H234 E103 E133 H136 E196 E230 H233 1.14.13.236 0004497,0009056,0016491,0018638,0042203,0046872 -logKd/Ki=5.30, Ki~5uM Q00456 22264099 519 AMHPRKDWYELTRATNWTPSYVTEEQLFPERMSGHMGIPLEKWESYDEPYKTSYPEYVSIQREKDAGAYSVKAALERAKIYENSDPGWISTLKSHYGAIAVGEYAAVTGEGRMARFSKAPGNRNMATFGMMDELRHGQLQLFFPHEYCKKDRQFDWAWRAYHSNEWAAIAAKHFFDDIITGRDAISVAIMLTFSFETGFTNMQFLGLAADAAEAGDYTFANLISSIQTDESRHAQQGGPALQLLIENGKREEAQKKVDMAIWRAWRLFAVLTGPVMDYYTPLEDRSQSFKEFMYEWIIGQFERSLIDLGLDKPWYWDLFLKDIDELHHSYHMGVWYWRTTAWWNPAAGVTPEERDWLEEKYPGWNKRWGRCWDVITENVLNDRMDLVSPETLPSVCNMSQIPLVGVPGDDWNIEVFSLEHNGRLYHFGSEVDRWVFQQDPVQYQNHMNIVDRFLAGQIQPMTLEGALKYMGFQSIEEMGKDAHDFAWADKC 3q2a A 1.99 BS04 PAB A 2 W167 P403 M471 W166 P402 M470 E104 E134 H137 E197 E231 H234 E103 E133 H136 E196 E230 H233 1.14.13.236 0004497,0009056,0016491,0018638,0042203,0046872 -logKd/Ki=5.30, Ki~5uM Q00456 22264099 520 AMHPRKDWYELTRATNWTPSYVTEEQLFPERMSGHMGIPLEKWESYDEPYKTSYPEYVSIQREKDAGAYSVKAALERAKIYENSDPGWISTLKSHYGAIAVGEYAAVTGEGRMARFSKAPGNRNMATFGMMDELRHGQLQLFFPHEYCKKDRQFDWAWRAYHSNEWAAIAAKHFFDDIITGRDAISVAIMLTFSFETGFTNMQFLGLAADAAEAGDYTFANLISSIQTDESRHAQQGGPALQLLIENGKREEAQKKVDMAIWRAWRLFAVLTGPVMDYYTPLEDRSQSFKEFMYEWIIGQFERSLIDLGLDKPWYWDLFLKDIDELHHSYHMGVWYWRTTAWWNPAAGVTPEERDWLEEKYPGWNKRWGRCWDVITENVLNDRMDLVSPETLPSVCNMSQIPLVGVPGDDWNIEVFSLEHNGRLYHFGSEVDRWVFQQDPVQYQNHMNIVDRFLAGQIQPMTLEGALKYMGFQSIEEMGKDAHDFAWADKC 3q2a A 1.99 BS05 PAB A 3 E104 E134 F176 I180 E197 E231 E103 E133 F175 I179 E196 E230 E104 E134 H137 E197 E231 H234 E103 E133 H136 E196 E230 H233 1.14.13.236 0004497,0009056,0016491,0018638,0042203,0046872 -logKd/Ki=5.30, Ki~5uM Q00456 22264099 521 AMHPRKDWYELTRATNWTPSYVTEEQLFPERMSGHMGIPLEKWESYDEPYKTSYPEYVSIQREKDAGAYSVKAALERAKIYENSDPGWISTLKSHYGAIAVGEYAAVTGEGRMARFSKAPGNRNMATFGMMDELRHGQLQLFFPHEYCKKDRQFDWAWRAYHSNEWAAIAAKHFFDDIITGRDAISVAIMLTFSFETGFTNMQFLGLAADAAEAGDYTFANLISSIQTDESRHAQQGGPALQLLIENGKREEAQKKVDMAIWRAWRLFAVLTGPVMDYYTPLEDRSQSFKEFMYEWIIGQFERSLIDLGLDKPWYWDLFLKDIDELHHSYHMGVWYWRTTAWWNPAAGVTPEERDWLEEKYPGWNKRWGRCWDVITENVLNDRMDLVSPETLPSVCNMSQIPLVGVPGDDWNIEVFSLEHNGRLYHFGSEVDRWVFQQDPVQYQNHMNIVDRFLAGQIQPMTLEGALKYMGFQSIEEMGKDAHDFAWADKC 3q2a A 1.99 BS06 PAB A 4 H447 M448 R453 Q458 H446 M447 R452 Q457 E104 E134 H137 E197 E231 H234 E103 E133 H136 E196 E230 H233 1.14.13.236 0004497,0009056,0016491,0018638,0042203,0046872 -logKd/Ki=5.30, Ki~5uM Q00456 22264099 522 AMHPRKDWYELTRATNWTPSYVTEEQLFPERMSGHMGIPLEKWESYDEPYKTSYPEYVSIQREKDAGAYSVKAALERAKIYENSDPGWISTLKSHYGAIAVGEYAAVTGEGRMARFSKAPGNRNMATFGMMDELRHGQLQLFFPHEYCKKDRQFDWAWRAYHSNEWAAIAAKHFFDDIITGRDAISVAIMLTFSFETGFTNMQFLGLAADAAEAGDYTFANLISSIQTDESRHAQQGGPALQLLIENGKREEAQKKVDMAIWRAWRLFAVLTGPVMDYYTPLEDRSQSFKEFMYEWIIGQFERSLIDLGLDKPWYWDLFLKDIDELHHSYHMGVWYWRTTAWWNPAAGVTPEERDWLEEKYPGWNKRWGRCWDVITENVLNDRMDLVSPETLPSVCNMSQIPLVGVPGDDWNIEVFSLEHNGRLYHFGSEVDRWVFQQDPVQYQNHMNIVDRFLAGQIQPMTLEGALKYMGFQSIEEMGKDAHDFAWADKC 3q2a B 1.99 BS01 PAB A 4 S41 E44 L45 S40 E43 L44 1.14.13.236 0004497,0009056,0016491,0016709,0018638,0042203 Q00460 22264099 522 SFESKKPMRTWSHLAEMRKKPSEYDIVSRKLHYSTNNPDSPWELSPDSPMNLWYKQYRNASPLKHDNWDAFTDPDQLVYRTYNLMQDGQESYVQSLFDQFNEREHDQMVREGWEHTMARCYSPLRYLFHCLQMSSAYVQQMAPASTISNCCILQTADSLRWLTHTAYRTHELSLTYPDAGLGEHERELWEKEPGWQGLRELMEKQLTAFDWGEAFVSLNLVVKPMIVESIFKPLQQQAWENNDTLLPLLIDSQLKDAERHSRWSKALVKHALENPDNHAVIEGWIEKWRPLADRAAEAYLSMLSS 3tyz A 2.07 BS03 PAB A 1 F28 T62 R63 F190 K221 S222 F28 T62 R63 F190 K221 S222 K221 R255 K221 R255 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 A0A2S9PLG4 22383850 280 MHLTARGLTLDLSRPQVMGILNVTPDSFSDGGCHNNLDQALQHAQRMLSAGATLIDIGGESTRPGAAEVSEQEELDRVVPVVEALAQRFDVWLSVDTSKAAVITESAHAGAHLINDIRSLQEPGALEAAAKTGLPVCLMHMQGQPKNMQHSPYYDDLMTDINRFFQHHIERCVAAGIAKNKLLLDPGFGFGKNLAHNYQLLAHLSELHHFELPLLVGMSRKSMVGQLLNVPPQQRVIGSVACAVIAAMQGAQIIRVHDVKETVEAMCIVEATRSA 3tyz B 2.07 BS03 PAB B 1 F28 T62 R63 G189 F190 K221 S222 F28 T62 R63 G189 F190 K221 S222 K221 R255 K221 R255 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 A0A2S9PLG4 22383850 280 MHLTARGLTLDLSRPQVMGILNVTPDSFSDGGCHNNLDQALQHAQRMLSAGATLIDIGGESTRPGAAEVSEQEELDRVVPVVEALAQRFDVWLSVDTSKAAVITESAHAGAHLINDIRSLQEPGALEAAAKTGLPVCLMHMQGQPKNMQHSPYYDDLMTDINRFFQHHIERCVAAGIAKNKLLLDPGFGFGKNLAHNYQLLAHLSELHHFELPLLVGMSRKSMVGQLLNVPPQQRVIGSVACAVIAAMQGAQIIRVHDVKETVEAMCIVEATRSAK 5z79 A 2.9 BS03 PAB A 1 F348 S382 A383 P384 G551 F552 K581 R582 F302 S336 A337 P338 G492 F493 K522 R523 2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0016740,0042558,0044237,0046654,0046656,0046872 A5JZS1 30104413 1103 TPRNIAVLNFGTNDKKNCVTILETALYLTEKYLGKIINSSYIYETVPEYIVRDISWIGDLIPTVENSRYEESEDLIYECKELEVFLKNEKINESIIREVSVEDYENEARRIIKRNDEIMKKNLTSYFFNLTVVVRTFVEDPLAMLVILKYIEQIMKNRMIDIDILFFNNYTIFEKSISLKGEDIYKIITKYIHINHTSDQNRLDIIQNLGDKIEFLCIPHVYTKYRYSILLCLNDIIPEYKHSTFEEAIRSTYNSYVESFEEKYHINIRKNNKRLYVLKDKVSYLKERTHIVGILNVNYDSFSDGGLFVDPVKAVERMFEMASDGASVIDIGGESSAPYVVPNPSVTERDLVMPVLKLFKEEWHKLECEVGGGAVSSLQGKLQKVRDAKPIISIDTVNYDLFKECVEGELVDILNDISACTHNPEIIKLLRRKNKFYSVVLMHKRGNPHTMDKLTNYDDLISDIKRYLEDRLHFLVLNGVPRYRVLFDVGLGFAKKHDQSIKLLQHIHVYDEYPLFLGYSRKRFIVHCMWRFKMSHMRQDKDQLLYQKNICGGLAIASYSFYKKVDLIRVHDVLETKAVLDVLTRIHQ 5z79 B 2.9 BS02 PAB B 1 F348 S382 A383 P384 F552 K581 R582 F291 S325 A326 P327 F480 K509 R510 2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0016740,0042558,0044237,0046654,0046656,0046872 A5JZS1 30104413 1103 PRNIAVLNFGTNDKKNCVTILETALYLTEKYLGKIINSSYIYETVPISWIGDLIPTVENSRYEESEDLIYECKELEVFLKNEKINESIIREVSVEDYENEARRIIKRNDEIMKKYFFNLTVVVRTFVEDPLAMLVILKYIEQIMKNRMIDIDILFFNNYTIFEKSISLKGEDIYKIITKYIHINHTSDQNRLDIIQNLGDKIEFLCIPHVYTKYRYSILLCLNDIIPEYKHSTFEEAIRSTYNSYVESFEEKYHINIRKNNKRLYVLKDKVSYLKERTHIVGILNVNYDSFSDGGLFVDPVKAVERMFEMASDGASVIDIGGESSAPYVVPNPSVTERDLVMPVLKLFKEEWHKLECEVGGQSSLQGKLQKVRDAKPIISIDTVNYDLFKECVEGELVDILNDISACTHNPEIIKLLRRKNKFYSVVLMHKRGNPHTMDKLTNYDDLISDIKRYLEDRLHFLVLNGVPRYRVLFDVGLGFAKKHDQSIKLLQHIHVYDEYPLFLGYSRKRFIVHCMLLYQKNICGGLAIASYSFYKKVDLIRVHDVLETKAVLDVLTRIHQP 5z79 C 2.9 BS03 PAB C 1 S382 A383 G551 F552 K581 R582 S349 A350 G503 F504 K533 R534 2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0016740,0042558,0044237,0046654,0046656,0046872 A5JZS1 30104413 1103 TPRNIAVLNFGTNDKKNCVTILETALYLTEKYLGKIINSSYIYETVPEYIIGEVTEGERDISWIGDLIPTVENSRYEESEDLIYECKELEVFLKNEKINESIIREVSVEDYENEARRIIKRNDEIMKKNLEQDKYYTSYFFNLTVVVRTFVEDPLAMLVILKYIEQIMKNRMIDIDILFFNNYTIFEKSISLKGEDIYKIITKYIHINHTSDQNRLDIIQNLGDKIEFLCIPHVYTKYRYSILLCLNDIIPEYKHSTFEEAIRSTYNSYVESFEEKYHINIRKNNKRLYVLKDKVSYLKERTHIVGILNVNYDSFSDGGLFVDPVKAVERMFEMASDGASVIDIGGESSAPYVVPNPSVTERDLVMPVLKLFKEEWHKLECEVGGGSSLQGKLQKVRDAKPIISIDTVNYDLFKECVEGELVDILNDISACTHNPEIIKLLRRKNKFYSVVLMHKRGNPHTMDKLTNYDDLISDIKRYLEDRLHFLVLNGVPRYRVLFDVGLGFAKKHDQSIKLLQHIHVYDEYPLFLGYSRKRFIVHCMWRFKMSHMRQDKDQLLYQKNICGGLAIASYSFYKKVDLIRVHDVLETKAVLDVLTRIHQ 5z79 D 2.9 BS02 PAB D 1 F348 S382 A383 P384 G551 F552 K581 R582 F307 S341 A342 P343 G494 F495 K524 R525 2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0016740,0042558,0044237,0046654,0046656,0046872 A5JZS1 30104413 1103 RNIAVLNFGTNDKKNCVTILETALYLTEKYLGKIINSSYIYETVPEYIGEVTPRDISWIGDLIPTVENSRYEESEDLIYECKELEVFLKNEKINESIIREVSVEDYENEARRIIKRNDEIMKKNLEQYYTSYFFNLTVVVRTFVEDPLAMLVILKYIEQIMKRMIDIDILFFNNYTIFEKSISLKGEDIYKIITKYIHINHTSDQNRLDIIQNLGDKIEFLCIPHVYTKYRYSILLCLNDIIPEYKHSTFEEAIRSTYNSYVESFEEKYHINIRKNNKRLYVLKDKVSYLKERTHIVGILNVNYDSFSDGGLFVDPVKAVERMFEMASDGASVIDIGGESSAPYVVPNPSVTERDLVMPVLKLFKEEWHKLECEVGGGSLQGKLQKVRDAKPIISIDTVNYDLFKECVEGELVDILNDISACTHNPEIIKLLRRKNKFYSVVLMHKRGNPHTMDKLTNYDDLISDIKRYLEDRLHFLVLNGVPRYRVLFDVGLGFAKKHDQSIKLLQHIHVYDEYPLFLGYSRKRFIVHCMQLLYQKNICGGLAIASYSFYKKVDLIRVHDVLETKAVLDVLTRIHQ 5z79 E 2.9 BS02 PAB E 1 S382 A383 P384 G551 F552 K581 R582 S332 A333 P334 G487 F488 K517 R518 2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0016740,0042558,0044237,0046654,0046656,0046872 A5JZS1 30104413 1102 TPRNIAVLNFGTNDKKNCVTILETALYLTEKYLGKIINSSYIYETVPEYIVRDISWIGDLIPTVENSRYEESEDLIYECKELEVFLKNEKINESIIREVSVEDYENEARRIIKRNDEIMKKNYFFNLTVVVRTFVEDPLAMLVILKYIEQIMKRMIDIDILFFNNYTIFEKSISLKGEDIYKIITKYIHINHTSDQNRLDIIQNLGDKIEFLCIPHVYTKYRYSILLCLNDIIPEYKHSTFEEAIRSTYNSYVESFEEKYHINIRKNNKRLYVLKDKVSYLKERTHIVGILNVNYDSFSDGGLFVDPVKAVERMFEMASDGASVIDIGGESSAPYVVPNPSVTERDLVMPVLKLFKEEWHKLECEVGGGASSLQGKLQKVRDAKPIISIDTVNYDLFKECVEGELVDILNDISACTHNPEIIKLLRRKNKFYSVVLMHKRGNPHTMDKLTNYDDLISDIKRYLEDRLHFLVLNGVPRYRVLFDVGLGFAKKHDQSIKLLQHIHVYDEYPLFLGYSRKRFIVHCMLWRFKMSHMRQDKDQLLYQKNICGGLAIASYSFYKKVDLIRVHDVLETKAVLDVLTRIHQ 5z79 F 2.9 BS02 PAB F 1 S382 A383 P384 F552 K581 R582 S331 A332 P333 F484 K513 R514 2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0016740,0042558,0044237,0046654,0046656,0046872 A5JZS1 30104413 1102 PRNIAVLNFGTNDKKNCVTILETALYLTEKYLGKIINSSYIYETVPEYPRDISWIGDLIPTVENSRYEESEDLIYECKELEVFLKNEKINESIIREVSVEDYENEARRIIKRNDEIMKKNLYTSYFFNLTVVVRTFVEDPLAMLVILKYIEQIMKRMIDIDILFFNNYTIFEKSISLKGEDIYKIITKYIHINHTNRLDIIQNLGDKIEFLCIPHVYTKYRYSILLCLNDIIPEYKHSTFEEAIRSTYNSYVESFEEKYHINIRKNNKRLYVLKDKVSYLKERTHIVGILNVNYDSFSDGGLFVDPVKAVERMFEMASDGASVIDIGGESSAPYVVPNPSVTERDLVMPVLKLFKEEWHKLECEVGGGLQGKLQKVRDAKPIISIDTVNYDLFKECVEGELVDILNDISACTHNPEIIKLLRRKNKFYSVVLMHKRGNPHTMDKLTNYDDLISDIKRYLEDRLHFLVLNGVPRYRVLFDVGLGFAKKHDQSIKLLQHIHVYDEYPLFLGYSRKRFIVHCMQLLYQKNICGGLAIASYSFYKKVDLIRVHDVLETKAVLDVLTRIHQ 6day A 1.65 BS01 PAB A 1 A243 V246 A220 V223 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 401 SPRLDCAGRILTLDRPRVMGIVNVTPDSFTHTTVEAAVAHGLRLAEEGADLLDIGGESAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 6day A 1.65 BS02 PAB A 2 A47 H48 A39 H40 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 402 SPRLDCAGRILTLDRPRVMGIVNVTPDSFTHTTVEAAVAHGLRLAEEGADLLDIGGESAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 6day B 1.65 BS01 PAB A 1 V242 A243 V246 V229 A230 V233 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 401 SPRLDCAGRILTLDRPRVMGIVNVTPDSFSDGGTHTTVEAAVAHGLRLAEEGADLLDIGGESTRPGATAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 6day B 1.65 BS02 PAB B 1 G194 F195 K226 R227 G181 F182 K213 R214 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 401 SPRLDCAGRILTLDRPRVMGIVNVTPDSFSDGGTHTTVEAAVAHGLRLAEEGADLLDIGGESTRPGATAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 6day B 1.65 BS03 PAB B 2 T72 A73 V74 R82 T68 A69 V70 R78 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 402 SPRLDCAGRILTLDRPRVMGIVNVTPDSFSDGGTHTTVEAAVAHGLRLAEEGADLLDIGGESTRPGATAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 6day B 1.65 BS04 PAB B 3 A47 H48 R51 A43 H44 R47 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 403 SPRLDCAGRILTLDRPRVMGIVNVTPDSFSDGGTHTTVEAAVAHGLRLAEEGADLLDIGGESTRPGATAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 6day C 1.65 BS01 PAB B 2 A47 H48 A41 H42 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 402 DTSPRLDCAGRILTLDRPRVMGIVNVTPDSFTHTTVEAAVAHGLRLAEEGADLLDIGGESVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPAGSAPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 6day C 1.65 BS02 PAB C 1 A243 V246 A267 A225 V228 A249 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 401 DTSPRLDCAGRILTLDRPRVMGIVNVTPDSFTHTTVEAAVAHGLRLAEEGADLLDIGGESVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPAGSAPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 6day D 1.65 BS01 PAB A 2 T72 A73 R82 T69 A70 R79 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 402 TSPRLDCAGRILTLDRPRVMGIVNVTPDSFSDGGTHTTVEAAVAHGLRLAEEGADLLDIGGESTRPGATAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPGDAPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 6day D 1.65 BS02 PAB C 1 V242 A243 V246 V233 A234 V237 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 401 TSPRLDCAGRILTLDRPRVMGIVNVTPDSFSDGGTHTTVEAAVAHGLRLAEEGADLLDIGGESTRPGATAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPGDAPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 6day D 1.65 BS03 PAB D 1 G194 F195 K226 R227 G185 F186 K217 R218 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 401 TSPRLDCAGRILTLDRPRVMGIVNVTPDSFSDGGTHTTVEAAVAHGLRLAEEGADLLDIGGESTRPGATAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPGDAPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 6day D 1.65 BS04 PAB D 2 A47 H48 R51 A44 H45 R48 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 D2UDM3 403 TSPRLDCAGRILTLDRPRVMGIVNVTPDSFSDGGTHTTVEAAVAHGLRLAEEGADLLDIGGESTRPGATAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPGDAPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 7pd5 A 1.95 BS01 PAB A 1 P47 S78 G110 K111 P46 S77 G109 K110 2.4.1.266 0000166,0016757,0046872 K5B7Z4 401 TLVPDLTATDLARHRWLTDNSWTRPTWTVAELEAAKAGRTISVVLPALNEEETVGGVVETIRPLLGGLVDELIVLDSGSTDDTEIRAMAAGARVISREVALPEVAPQPGKGEVLWRSLAATTGDIIVFIDSDLIDPDPMFVPKLVGPLLLSEGVHLVKGFYRRGGRVTELVARPLLAALRPELTCVLQPLGGEYAGTRELLMSVPFAPGYGVEIGLLVDTYDRLGLDAIAQVNLGVRAHRNRPLTDLAAMSRQVIATLFSRCGVPDSGVGLTQFFGFSPRTSEVSLVDRPPMNTLRGKLAAAL 7r86 A 1.65 BS02 PAB A 1 Y34 R61 W87 Y9 R36 W62 ? Q99PI8 34758294 403 SCPGACVCYNEPKVTTSCPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCNLPQRLADRDLKRLAASDLEGC 7r86 B 1.65 BS02 PAB A 1 H65 W87 H41 W63 ? Q99PI8 34758294 403 ASCPGACVCYNEPKVTTSCPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCNLPQRLADRDLKRLAASDLEGC 7s2k B 1.74 BS02 PAB B 1 N53 R247 H249 N44 R238 H240 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046677,0046872 P0AC11 37419898 302 MNKSLIIFGIVNITYLAPDAAIAQARKLMAEGADVIDLGPASSNPDAAPVSSDTEIARIAPVLDALKADGIPVSLDSYQPATQAYALSRGVAYLNDIRGFPDAAFYPQLAKSSAKLVVMHSVQDGQADRREAPAGDIMDHIAAFFDARIAALTGAGIKRNRLVLDPGMGFFLGAAPETSLSVLARFDELRLRFDLPVLLSVSRKSFLRALTGRGPGDVGAATLAAELAAAAGGADFIRTHEPRPLRDGLAVLAALKETARI 8scd A 2.06 BS02 PAB A 1 F15 S49 N50 G176 F177 F178 K211 S212 F16 S50 N51 G177 F178 F179 K212 S213 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 Q8GJ22 37419898 302 GMSKIFGIVNITTDSFSDGGLYLDTDKAIEHALHLVEDGADVIDLGAASSNPDTTEVGVVEEIKRLKPVIKALKEKGISISVDTFKPEVQSFCIEQKVDFINDIQGFPYPEIYSGLAKSDCKLVLMHSVQRIGAATKVETNPAAVFTSMMEFFKERIAALVEAGVKRERIILDPGMGFFLGSNPETSILVLKRFPEIQEAFNLQVMIAVSRKSFLGKITGTDVKSRLAPTLAAEMYAYKKGADYLRTHDVKSLSDALKISKALG