6pyc H 3.6 BS01 P4S H 1 Y97 I100 Y96 I99 -logKd/Ki=7.45, Kd=35.8nM 31879340 301 IVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWFQQKPGQPPKLLIYWASLRESGVSDRFSGSGSGTDFTLTISGLQAEDVAVYYCQQYYSILWTFGQGTKVEIKSTKGPSVFPLAPCTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVES 6pyc H 3.6 BS02 P4S L 1 Q95 W102 Q94 W101 -logKd/Ki=7.45, Kd=35.8nM 31879340 301 IVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWFQQKPGQPPKLLIYWASLRESGVSDRFSGSGSGTDFTLTISGLQAEDVAVYYCQQYYSILWTFGQGTKVEIKSTKGPSVFPLAPCTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVES 6pyc L 3.6 BS01 P4S L 1 Q90 Y92 Y97 Q90 Y92 Y97 -logKd/Ki=7.45, Kd=35.8nM 31879340 301 EIVLTQSPGTLSLSPGERATLSCRASQSVGNNYLAWFQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFVVYYCQQYSRSPYIFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG 6pyd A 2.0 BS01 P4S B 1 Y100 G101 G103 Y99 G100 G102 31879340 301 VQLQESGPSLVKPSQTLSLTCSVTGDSITSGYWNWIRKFPGNKLEYMGYISYSGTTYYNPSLKSRISITRDTSKNQYYLQLNSVTTEDTATYYCARARYGYGFDYWGQGTTLTVSSASTKGPSVFPLAPCSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVE 6pyd B 2.0 BS01 P4S B 1 Y36 E38 G95 Y33 E35 G92 31879340 301 DVLMTQTPLSLPVSLGDQASISCRSSQSIVNTYLEWYLQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYYCFQGSHVPLTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFN 6pyd H 2.0 BS01 P4S H 1 Y50 Y100 G101 G103 Y49 Y99 G100 G102 -logKd/Ki=6.81, Kd=156nM 31879340 301 VQLQESGPSLVKPSQTLSLTCSVTGDSITSGYWNWIRKFPGNKLEYMGYISYSGTTYYNPSLKSRISITRDTSKNQYYLQLNSVTTEDTATYYCARARYGYGFDYWGQGTTLTVSSASTKGPSVFPLAPTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKY 6pyd L 2.0 BS01 P4S H 1 Y36 E38 G95 Y29 E31 G88 -logKd/Ki=6.81, Kd=156nM 31879340 301 VLMTQTPLSLPVSLGDQASISCRSSQSTYLEWYLQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYYCFQGSHVPLTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR