3oof A 2.29 BS02 OOF A 1 I277 L291 M294 M332 F333 R335 S336 F340 I356 S359 M369 Y373 I31 L45 M48 M86 F87 R89 S90 F94 I110 S113 M123 Y127 ? 0003677,0004879,0006355,0032052,0038183 -logKd/Ki=7.30, IC50=50nM IC50=50nM, EC50=2500nM Q96RI1 21269824 1 MELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEAFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEARIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ 3oof C 2.29 BS02 OOF C 1 I273 L291 M294 M332 F333 R335 S336 I339 F340 I356 S359 M369 Y373 I27 L45 M48 M86 F87 R89 S90 I93 F94 I110 S113 M123 Y127 ? 0003677,0004879,0006355,0032052,0038183 IC50=50nM, EC50=2500nM Q96RI1 21269824 2 MELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEAFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEARIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ