1t31 A 1.9 BS02 OHH A 1 K40 H57 A190 F191 K192 G193 S195 S214 Y215 G216 R217 A226 K28 H45 A177 F178 K179 G180 S182 S197 Y198 G199 R200 A207 H57 D102 K192 G193 D194 S195 G196 H45 D89 K179 G180 D181 S182 G183 3.4.21.39 0002003,0004175,0004252,0005576,0005615,0005737,0005829,0006508,0006518,0008236,0016485,0022617,0030141,0030163,0030901,0034769,0036464,0042277,0043231,0045766,0050727,0062023,0071333,0140447 Ki=2.3nM -logKd/Ki=8.64, Ki=2.3nM Ki=2.3nM, IC50=4.5nM P23946 15741158 901 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQKNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGAAQGIVSYGRSDAKPPAVFTRISHYQPWINQILQAN 1t32 A 1.85 BS01 OHH A 1 H57 F172 A190 F191 K192 G193 S195 S214 Y215 G216 E226 H44 F156 A176 F177 K178 G179 S181 S196 Y197 G198 E206 H57 D102 K192 G193 D194 S195 G196 H44 D88 K178 G179 D180 S181 G182 3.4.21.20 0002003,0002548,0004252,0005515,0005576,0005615,0005634,0005737,0005764,0005829,0005886,0006468,0006508,0006935,0006955,0008201,0008233,0008236,0010494,0016020,0016485,0019221,0019731,0022617,0030141,0030168,0032496,0035578,0035590,0042119,0042742,0043231,0048018,0050778,0050829,0050830,0050832,0050868,0062023,0070062,0070946,0071222,0089720,0098786,1901731 Ki=38nM -logKd/Ki=7.42, Ki=38nM Ki=38nM P08311 15741158 901 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRS