5kd9 A 1.78 BS02 OBT A 1 M343 T347 A350 E353 L387 F404 M421 I424 H524 L525 M39 T43 A46 E49 L83 F100 M117 I120 H211 L212 ? ic50=0.93uM P03372 27870835 601 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5kd9 B 1.78 BS02 OBT B 1 M343 L346 T347 E353 L387 M421 I424 G521 L525 L544 M39 L42 T43 E49 L83 M117 I120 G208 L212 L225 ? ic50=0.93uM P03372 27870835 601 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSVPLSDLLLEMLDAH 8w03 A 1.68 BS01 OBT A 1 L346 T347 A350 E353 L387 M421 G521 V533 L41 T42 A45 E48 L82 M116 G216 V228 ? P03372 38830107 600 LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPSYDLLLEMLDA 8w03 B 1.68 BS01 OBT B 1 T347 E353 L387 V418 G420 I424 F425 G521 T38 E44 L78 V109 G111 I115 F116 G212 ? P03372 38830107 600 SLALSLTADQMVSALLDAEPPILYSEYDPTRSMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSVVPSYDLLLEMLDA 8w03 C 1.68 BS01 OBT C 1 M343 L346 T347 A350 E353 L387 G415 V418 M421 I424 F425 G521 V533 M38 L41 T42 A45 E48 L82 G110 V113 M116 I119 F120 G216 V228 ? P03372 38830107 600 LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPSYDLLLEMLDA 8w03 D 1.68 BS01 OBT D 1 M342 M343 L346 T347 A350 E353 L387 M421 F425 H524 L525 M528 V533 M33 M34 L37 T38 A41 E44 L78 M107 F111 H206 L207 M210 V211 ? P03372 38830107 600 SLALSLTADQMVSALLDAEPPILYSEYDPTRSMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMVVPSYDLLLEMLDA