6xz8 A 3.0 BS02 O4T A 1 W116 F130 W260 A313 G314 T318 V378 F487 W83 F97 W227 A280 G281 T285 V345 F449 T318 F443 C450 T285 F405 C412 1.14.15.4,1.14.15.5 0002017,0003091,0004497,0004507,0005506,0005739,0005743,0006629,0006694,0006700,0006704,0006705,0008203,0008395,0016125,0016705,0020037,0032342,0032870,0034650,0034651,0035865,0046872,0047783,0055075,0055078,0071375,1901615 IC50=8.0nM P19099 32530624 602 TVLPFEAMPQHPGNRWLRLLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDINFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSFILRPGTSPLLTFRAIN 6xz8 B 3.0 BS02 O4T B 1 W116 F130 W260 A313 G314 T318 F487 W85 F99 W229 A282 G283 T287 F456 T318 F443 C450 T287 F412 C419 1.14.15.4,1.14.15.5 0002017,0003091,0004497,0004507,0005506,0005739,0005743,0006629,0006694,0006700,0006704,0006705,0008203,0008395,0016125,0016705,0020037,0032342,0032870,0034650,0034651,0035865,0046872,0047783,0055075,0055078,0071375,1901615 IC50=8.0nM P19099 32530624 602 PRTVLPFEAMPQHPGNRWLRLLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSFILRPGTSPLLTFRAING 6xz8 C 3.0 BS02 O4T C 1 W116 F130 F231 W260 A313 G314 T318 V378 W83 F97 F198 W227 A280 G281 T285 V345 T318 F443 C450 T285 F406 C413 1.14.15.4,1.14.15.5 0002017,0003091,0004497,0004507,0005506,0005739,0005743,0006629,0006694,0006700,0006704,0006705,0008203,0008395,0016125,0016705,0020037,0032342,0032870,0034650,0034651,0035865,0046872,0047783,0055075,0055078,0071375,1901615 IC50=8.0nM P19099 32530624 602 TVLPFEAMPQHPGNRWLRLLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSFILRPGTSPLLTFRAIN