4bbf A 2.0 BS01 O19 A 1 L855 G858 G861 V863 A880 Y931 L932 G935 D994 L15 G18 G21 V23 A40 Y91 L92 G95 D154 N976 A978 R980 N981 D994 S1016 N136 A138 R140 N141 D154 S176 2.7.10.2 0004672,0005524,0006468 ic50=2.2nM -logKd/Ki=8.66, IC50=2.2nM IC50=2.2nM O60674 23127890 2229 PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRD 4bbf B 2.0 BS01 O19 B 1 L855 K857 G861 V863 A880 Y931 L932 G935 L15 K17 G21 V23 A40 Y91 L92 G95 N976 A978 R980 N981 D994 S1016 N136 A138 R140 N141 D154 S176 2.7.10.2 0004672,0005524,0006468 ic50=2.2nM IC50=2.2nM O60674 23127890 2229 PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRD 4bbf C 2.0 BS01 O19 C 1 L855 K857 G858 G861 V863 A880 Y931 L932 G935 L983 L15 K17 G18 G21 V23 A40 Y91 L92 G95 L143 N976 A978 R980 N981 D994 S1016 N136 A138 R140 N141 D154 S176 2.7.10.2 0004672,0005524,0006468 ic50=2.2nM IC50=2.2nM O60674 23127890 2229 PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRD 4bbf D 2.0 BS01 O19 D 1 L855 G861 V863 A880 Y931 L932 G935 L983 D994 L15 G21 V23 A40 Y91 L92 G95 L143 D154 N976 A978 R980 N981 D994 S1016 N136 A138 R140 N141 D154 S176 2.7.10.2 0004672,0005524,0006468 ic50=2.2nM IC50=2.2nM O60674 23127890 2229 PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRNLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRD