3qfv A 2.65 BS01 NM7 A 1 I82 G83 V90 T137 M153 Y156 F370 I81 G82 V89 T136 M152 Y155 F369 D200 K202 N205 D218 T239 D199 K201 N204 D217 T238 2.7.11.1 0004672,0004674,0005524,0006468 -logKd/Ki=5.77, IC50=1.69uM Q9Y5S2 21949762 416 SAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVSGLHLPFIGFTFTTESCFSDRGSL 3qfv B 2.65 BS01 NM7 B 1 V90 T137 M153 Y155 Y156 L207 F370 V89 T136 M152 Y154 Y155 L206 F369 D200 K202 N205 D218 T239 D199 K201 N204 D217 T238 2.7.11.1 0004672,0004674,0005524,0006468 Q9Y5S2 21949762 416 SAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDGFSGLHLPFIGFTFTTESCFSDRGSL 7ax4 A 2.12 BS01 NM7 A 1 Q597 V640 K642 T687 E688 Y689 V690 P694 L741 Q19 V37 K39 T84 E85 Y86 V87 P91 L138 N734 R738 N739 D759 N131 R135 N136 D156 2.7.10.2 0004672,0005524,0006468 P29597 33783261 2000 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 7ax4 B 2.12 BS01 NM7 B 1 Q597 V640 K642 T687 E688 Y689 V690 P694 L741 Q19 V37 K39 T84 E85 Y86 V87 P91 L138 N734 R738 N739 D759 N131 R135 N136 D156 2.7.10.2 0004672,0005524,0006468 P29597 33783261 2000 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR